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2018 Journal Article Extracorporeal carbon dioxide removal for lowering the risk of mechanical ventilation: research questions and clinical potential for the futureBoyle, Andrew J., Sklar, Michael C., McNamee, James J., Brodie, Daniel, Slutsky, Arthur S., Brochard, Laurent, McAuley, Daniel F., International ECMO Network (ECMONet) and Shekar, Kiran (2018). Extracorporeal carbon dioxide removal for lowering the risk of mechanical ventilation: research questions and clinical potential for the future. The Lancet. Respiratory medicine, 6 (11), 874-884. doi: 10.1016/S2213-2600(18)30326-6 |
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2018 Journal Article Unintended consequences: fluid resuscitation worsens shock in an ovine model of endotoxemiaByrne, Liam, Obonyo, Nchafatso G., Diab, Sara D., Dunster, Kimble R., Passmore, Margaret R., Boon, Ai-Ching, See Hoe, Louise, Pedersen, Sanne, Hashairi Fauzi, Mohd, Pretti Pimenta, Leticia, Van Haren, Frank, Anstey, Christopher M., Cullen, Louise, Tung, John-Paul, Shekar, Kiran, Maitland, Kathryn and Fraser, John F. (2018). Unintended consequences: fluid resuscitation worsens shock in an ovine model of endotoxemia. American Journal of Respiratory and Critical Care Medicine, 198 (8), 1043-1054. doi: 10.1164/rccm.201801-0064OC |
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2018 Journal Article An improved LC-MS/MS method for simultaneous evaluation of CYP2C9, CYP2C19, CYP2D6 and CYP3A4 activitySreevatsav Adiraju, Santosh Kumar, Shekar, Kiran, Fraser, John F., Smith, Maree T. and Ghassabian, Sussan (2018). An improved LC-MS/MS method for simultaneous evaluation of CYP2C9, CYP2C19, CYP2D6 and CYP3A4 activity. Bioanalysis, 10 (19), 1577-1590. doi: 10.4155/bio-2018-0102 |
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2018 Journal Article A mathematical model of CO2, O2 and N2 exchange during venovenous extracorporeal membrane oxygenationJoyce, Christopher John, Shekar, Kiran and Cook, David Andrew (2018). A mathematical model of CO2, O2 and N2 exchange during venovenous extracorporeal membrane oxygenation. Intensive Care Medicine Experimental, 6 (1) 25, 25. doi: 10.1186/s40635-018-0183-4 |
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2018 Journal Article Patient selection for VV ECMO: have we found the crystal ball?Ahuja, Abhilasha and Shekar, Kiran (2018). Patient selection for VV ECMO: have we found the crystal ball?. Journal of Thoracic Disease, 10 (Suppl 17), S1979-S1981. doi: 10.21037/jtd.2018.05.83 |
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2018 Journal Article MitoQ improves mitochondrial dysfunction in heart failure induced by pressure overloadRibeiro Junior, Rogério Faustino, Dabkowski, Erinne Rose, Shekar, Kadambari Chandra, O Connell, Kelly A., Hecker, Peter A. and Murphy, Michael P. (2018). MitoQ improves mitochondrial dysfunction in heart failure induced by pressure overload. Free Radical Biology and Medicine, 117, 18-29. doi: 10.1016/j.freeradbiomed.2018.01.012 |
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2018 Journal Article Optimising drug dosing in patients receiving extracorporeal membrane oxygenationCheng, Vesa, Abdul-Aziz, Mohd-Hafiz, Roberts, Jason A. and Shekar, Kiran (2018). Optimising drug dosing in patients receiving extracorporeal membrane oxygenation. Journal of Thoracic Disease, 10 (Suppl 5), S629-S641. doi: 10.21037/jtd.2017.09.154 |
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2018 Journal Article An improved liquid chromatography tandem mass spectrometry (LC-MS/MS) method for quantification of dexmedetomidine concentrations in samples of human plasmaMoosavi, Seyed Mojtaba, Shekar, Kiran, Fraser, John F., Smith, Maree T. and Ghassabian, Sussan (2018). An improved liquid chromatography tandem mass spectrometry (LC-MS/MS) method for quantification of dexmedetomidine concentrations in samples of human plasma. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 1073, 118-122. doi: 10.1016/j.jchromb.2017.12.006 |
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2018 Journal Article An ovine model of hyperdynamic endotoxemia and vital organ metabolismByrne, Liam, Obonyo, Nchafatso G., Diab, Sara, Dunster, Kimble, Passmore, Margaret, Boon, Ai Ching, Hoe, Louise See, Hay, Karen, Van Haren, Frank, Tung, John-Paul, Cullen, Louise, Shekar, Kiran, Maitland, Kathryn and Fraser, John F. (2018). An ovine model of hyperdynamic endotoxemia and vital organ metabolism. Shock, 49 (1), 99-107. doi: 10.1097/SHK.0000000000000904 |
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2018 Journal Article Unplanned autotransplantation for complex multi-valve replacement in a super morbid obese female: the challenge of intraoperative decision makingMcDonald, Charles, Dallimore, Daniel, Oates, Mathew, Shekar, Kiran and Thomson, Bruce (2018). Unplanned autotransplantation for complex multi-valve replacement in a super morbid obese female: the challenge of intraoperative decision making. Journal of Extra-Corporeal Technology, 50 (4), 248-251. |
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2017 Journal Article Effect of cardiopulmonary bypass on cytochrome P450 enzyme activity: implications for pharmacotherapyAdiraju, Santosh Kumar Sreevatsav, Shekar, Kiran, Fraser, John F, Smith, Maree T and Ghassabian, Sussan (2017). Effect of cardiopulmonary bypass on cytochrome P450 enzyme activity: implications for pharmacotherapy. Drug metabolism reviews, 50 (2), 1-16. doi: 10.1080/03602532.2017.1417423 |
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2017 Journal Article Incremental research approach to describing the pharmacokinetics of ciprofloxacin during extracorporeal membrane oxygenationSinnah, Fabrice, Shekar, Kiran, Abdul-Aziz, Mohd H, Buscher, Hergen, Diab, Sara D., Fisquet, Stephanie, Fung, Yoke L., McDonald, Charles I., Reynolds, Claire, Rudham, Sam, Wallis, Steven C., Welch, Susan, Xie, Jiao, Fraser, John F., Roberts, Jason A. and ASAP ECMO investigators (2017). Incremental research approach to describing the pharmacokinetics of ciprofloxacin during extracorporeal membrane oxygenation. Critical Care and Resuscitation, 19 (Suppl 1), 8-14. |
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2017 Journal Article Appraising extracorporeal life support — current and future roles in adult intensive careShekar, Kiran, Brodie, Daniel, Fraser, John and MacLaren, Graeme (2017). Appraising extracorporeal life support — current and future roles in adult intensive care. Critical Care and Resuscitation, 19, 5-7. |
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2017 Journal Article Evidence of altered haemostasis in an ovine model of venovenous extracorporeal membrane oxygenation supportPassmore, Margaret R., Fung, Yoke L., Simonova, Gabriela, Foley, Samuel R., Diab, Sara D., Dunster, Kimble R., Spanevello, Michelle M., McDonald, Charles I., Tung, John-Paul, Pecheniuk, Natalie M., Hay, Karen, Shekar, Kiran and Fraser, John F. (2017). Evidence of altered haemostasis in an ovine model of venovenous extracorporeal membrane oxygenation support. Critical Care, 21 (1) 191, 1-9. doi: 10.1186/s13054-017-1788-9 |
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2017 Journal Article Successful provision of inter-hospital extracorporeal cardiopulmonary resuscitation for acute post-partum pulmonary embolismMcDonald, C., Laurie, J., Janssens, S., Zazulak, C., Kotze, P. and Shekar, K. (2017). Successful provision of inter-hospital extracorporeal cardiopulmonary resuscitation for acute post-partum pulmonary embolism. International Journal of Obstetric Anesthesia, 30, 65-68. doi: 10.1016/j.ijoa.2017.01.003 |
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2017 Journal Article The effects of the introduction of an adult ECMO program on statewide referral patterns, casemix and outcomes in patients with acute respiratory distress syndrome or pneumoniaMullany, Dan, Shekar, Kiran, Ziegenfuss, Marc, Joyce, Christopher, Pilcher, David, Dobson, Annette and Fraser, John F. (2017). The effects of the introduction of an adult ECMO program on statewide referral patterns, casemix and outcomes in patients with acute respiratory distress syndrome or pneumonia. Intensive Care Medicine, 43 (7), 1065-1066. doi: 10.1007/s00134-017-4771-7 |
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2016 Journal Article Inflammation and lung injury in an ovine model of extracorporeal membrane oxygenation supportPassmore, Margaret R., Fung, Yoke L., Simonova, Gabriela, Foley, Samuel R., Dunster, Kimble R., Diab, Sara D., Tung, John-Paul, Minchinton, Robyn M., McDonald, Charles I., Anstey, Chris M., Shekar, Kiran and Fraser, John F. (2016). Inflammation and lung injury in an ovine model of extracorporeal membrane oxygenation support. AJP - Lung Cellular and Molecular Physiology, 311 (6), L1202-L1212. doi: 10.1152/ajplung.00296.2016 |
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2016 Journal Article High-throughput assay for quantification of the plasma concentrations of thiopental using automated solid phase extraction (SPE) directly coupled to LC–MS/MS instrumentationMoosavi, Seyed Mojtaba, Shekar, Kiran, Fraser, John, Smith, Maree T. and Ghassabian, Sussan (2016). High-throughput assay for quantification of the plasma concentrations of thiopental using automated solid phase extraction (SPE) directly coupled to LC–MS/MS instrumentation. Journal of Chromatography B, 1038, 80-87. doi: 10.1016/j.jchromb.2016.10.038 |
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2016 Journal Article Quantification of perflutren microsphere contrast destruction during transit through an ex vivo extracorporeal membrane oxygenation circuitPlatts, David G., McDonald, Charles, Shekar, Kiran, Burstow, Darryl J., Mullany, Daniel, Ziegenfuss, Marc, Diab, Sara and Fraser, John F. (2016). Quantification of perflutren microsphere contrast destruction during transit through an ex vivo extracorporeal membrane oxygenation circuit. Intensive Care Medicine Experimental, 4 (1) 7, 7. doi: 10.1186/s40635-016-0079-0 |
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2016 Journal Article Association between post-sternotomy tracheostomy and deep sternal wound infection: a retrospective analysisTsai, Yi-Chin, Phan, Kevin, Stroebel, Andrie, Williams, Livia, Nicotra, Lisa, Drake, Lesley, Ryan, Elizabeth, McGree, James, Tesar, Peter and Shekar, Kiran (2016). Association between post-sternotomy tracheostomy and deep sternal wound infection: a retrospective analysis. Journal of Thoracic Disease, 8 (11), 3294-3300. doi: 10.21037/jtd.2016.11.70 |
