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2018

Journal Article

A mathematical model of CO2, O2 and N2 exchange during venovenous extracorporeal membrane oxygenation

Joyce, Christopher John, Shekar, Kiran and Cook, David Andrew (2018). A mathematical model of CO2, O2 and N2 exchange during venovenous extracorporeal membrane oxygenation. Intensive Care Medicine Experimental, 6 (1) 25, 25. doi: 10.1186/s40635-018-0183-4

A mathematical model of CO2, O2 and N2 exchange during venovenous extracorporeal membrane oxygenation

2018

Journal Article

Patient selection for VV ECMO: have we found the crystal ball?

Ahuja, Abhilasha and Shekar, Kiran (2018). Patient selection for VV ECMO: have we found the crystal ball?. Journal of Thoracic Disease, 10 (Suppl 17), S1979-S1981. doi: 10.21037/jtd.2018.05.83

Patient selection for VV ECMO: have we found the crystal ball?

2018

Journal Article

MitoQ improves mitochondrial dysfunction in heart failure induced by pressure overload

Ribeiro Junior, Rogério Faustino, Dabkowski, Erinne Rose, Shekar, Kadambari Chandra, O Connell, Kelly A., Hecker, Peter A. and Murphy, Michael P. (2018). MitoQ improves mitochondrial dysfunction in heart failure induced by pressure overload. Free Radical Biology and Medicine, 117, 18-29. doi: 10.1016/j.freeradbiomed.2018.01.012

MitoQ improves mitochondrial dysfunction in heart failure induced by pressure overload

2018

Journal Article

Optimising drug dosing in patients receiving extracorporeal membrane oxygenation

Cheng, Vesa, Abdul-Aziz, Mohd-Hafiz, Roberts, Jason A. and Shekar, Kiran (2018). Optimising drug dosing in patients receiving extracorporeal membrane oxygenation. Journal of Thoracic Disease, 10 (Suppl 5), S629-S641. doi: 10.21037/jtd.2017.09.154

Optimising drug dosing in patients receiving extracorporeal membrane oxygenation

2018

Journal Article

An improved liquid chromatography tandem mass spectrometry (LC-MS/MS) method for quantification of dexmedetomidine concentrations in samples of human plasma

Moosavi, Seyed Mojtaba, Shekar, Kiran, Fraser, John F., Smith, Maree T. and Ghassabian, Sussan (2018). An improved liquid chromatography tandem mass spectrometry (LC-MS/MS) method for quantification of dexmedetomidine concentrations in samples of human plasma. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 1073, 118-122. doi: 10.1016/j.jchromb.2017.12.006

An improved liquid chromatography tandem mass spectrometry (LC-MS/MS) method for quantification of dexmedetomidine concentrations in samples of human plasma

2018

Journal Article

An ovine model of hyperdynamic endotoxemia and vital organ metabolism

Byrne, Liam, Obonyo, Nchafatso G., Diab, Sara, Dunster, Kimble, Passmore, Margaret, Boon, Ai Ching, Hoe, Louise See, Hay, Karen, Van Haren, Frank, Tung, John-Paul, Cullen, Louise, Shekar, Kiran, Maitland, Kathryn and Fraser, John F. (2018). An ovine model of hyperdynamic endotoxemia and vital organ metabolism. Shock, 49 (1), 99-107. doi: 10.1097/SHK.0000000000000904

An ovine model of hyperdynamic endotoxemia and vital organ metabolism

2018

Journal Article

Unplanned autotransplantation for complex multi-valve replacement in a super morbid obese female: the challenge of intraoperative decision making

McDonald, Charles, Dallimore, Daniel, Oates, Mathew, Shekar, Kiran and Thomson, Bruce (2018). Unplanned autotransplantation for complex multi-valve replacement in a super morbid obese female: the challenge of intraoperative decision making. Journal of Extra-Corporeal Technology, 50 (4), 248-251.

Unplanned autotransplantation for complex multi-valve replacement in a super morbid obese female: the challenge of intraoperative decision making

2017

Journal Article

Effect of cardiopulmonary bypass on cytochrome P450 enzyme activity: implications for pharmacotherapy

Adiraju, Santosh Kumar Sreevatsav, Shekar, Kiran, Fraser, John F, Smith, Maree T and Ghassabian, Sussan (2017). Effect of cardiopulmonary bypass on cytochrome P450 enzyme activity: implications for pharmacotherapy. Drug metabolism reviews, 50 (2), 1-16. doi: 10.1080/03602532.2017.1417423

Effect of cardiopulmonary bypass on cytochrome P450 enzyme activity: implications for pharmacotherapy

2017

Journal Article

Appraising extracorporeal life support — current and future roles in adult intensive care

Shekar, Kiran, Brodie, Daniel, Fraser, John and MacLaren, Graeme (2017). Appraising extracorporeal life support — current and future roles in adult intensive care. Critical Care and Resuscitation, 19, 5-7.

Appraising extracorporeal life support — current and future roles in adult intensive care

2017

Journal Article

Incremental research approach to describing the pharmacokinetics of ciprofloxacin during extracorporeal membrane oxygenation

Sinnah, Fabrice, Shekar, Kiran, Abdul-Aziz, Mohd H, Buscher, Hergen, Diab, Sara D., Fisquet, Stephanie, Fung, Yoke L., McDonald, Charles I., Reynolds, Claire, Rudham, Sam, Wallis, Steven C., Welch, Susan, Xie, Jiao, Fraser, John F., Roberts, Jason A. and ASAP ECMO investigators (2017). Incremental research approach to describing the pharmacokinetics of ciprofloxacin during extracorporeal membrane oxygenation. Critical Care and Resuscitation, 19 (Suppl 1), 8-14.

Incremental research approach to describing the pharmacokinetics of ciprofloxacin during extracorporeal membrane oxygenation

2017

Journal Article

Evidence of altered haemostasis in an ovine model of venovenous extracorporeal membrane oxygenation support

Passmore, Margaret R., Fung, Yoke L., Simonova, Gabriela, Foley, Samuel R., Diab, Sara D., Dunster, Kimble R., Spanevello, Michelle M., McDonald, Charles I., Tung, John-Paul, Pecheniuk, Natalie M., Hay, Karen, Shekar, Kiran and Fraser, John F. (2017). Evidence of altered haemostasis in an ovine model of venovenous extracorporeal membrane oxygenation support. Critical Care, 21 (1) 191, 1-9. doi: 10.1186/s13054-017-1788-9

Evidence of altered haemostasis in an ovine model of venovenous extracorporeal membrane oxygenation support

2017

Journal Article

Successful provision of inter-hospital extracorporeal cardiopulmonary resuscitation for acute post-partum pulmonary embolism

McDonald, C., Laurie, J., Janssens, S., Zazulak, C., Kotze, P. and Shekar, K. (2017). Successful provision of inter-hospital extracorporeal cardiopulmonary resuscitation for acute post-partum pulmonary embolism. International Journal of Obstetric Anesthesia, 30, 65-68. doi: 10.1016/j.ijoa.2017.01.003

Successful provision of inter-hospital extracorporeal cardiopulmonary resuscitation for acute post-partum pulmonary embolism

2017

Journal Article

The effects of the introduction of an adult ECMO program on statewide referral patterns, casemix and outcomes in patients with acute respiratory distress syndrome or pneumonia

Mullany, Dan, Shekar, Kiran, Ziegenfuss, Marc, Joyce, Christopher, Pilcher, David, Dobson, Annette and Fraser, John F. (2017). The effects of the introduction of an adult ECMO program on statewide referral patterns, casemix and outcomes in patients with acute respiratory distress syndrome or pneumonia. Intensive Care Medicine, 43 (7), 1065-1066. doi: 10.1007/s00134-017-4771-7

The effects of the introduction of an adult ECMO program on statewide referral patterns, casemix and outcomes in patients with acute respiratory distress syndrome or pneumonia

2016

Journal Article

Inflammation and lung injury in an ovine model of extracorporeal membrane oxygenation support

Passmore, Margaret R., Fung, Yoke L., Simonova, Gabriela, Foley, Samuel R., Dunster, Kimble R., Diab, Sara D., Tung, John-Paul, Minchinton, Robyn M., McDonald, Charles I., Anstey, Chris M., Shekar, Kiran and Fraser, John F. (2016). Inflammation and lung injury in an ovine model of extracorporeal membrane oxygenation support. AJP - Lung Cellular and Molecular Physiology, 311 (6), L1202-L1212. doi: 10.1152/ajplung.00296.2016

Inflammation and lung injury in an ovine model of extracorporeal membrane oxygenation support

2016

Journal Article

Quantification of perflutren microsphere contrast destruction during transit through an ex vivo extracorporeal membrane oxygenation circuit

Platts, David G., McDonald, Charles, Shekar, Kiran, Burstow, Darryl J., Mullany, Daniel, Ziegenfuss, Marc, Diab, Sara and Fraser, John F. (2016). Quantification of perflutren microsphere contrast destruction during transit through an ex vivo extracorporeal membrane oxygenation circuit. Intensive Care Medicine Experimental, 4 (1) 7, 7. doi: 10.1186/s40635-016-0079-0

Quantification of perflutren microsphere contrast destruction during transit through an ex vivo extracorporeal membrane oxygenation circuit

2016

Journal Article

High-throughput assay for quantification of the plasma concentrations of thiopental using automated solid phase extraction (SPE) directly coupled to LC–MS/MS instrumentation

Moosavi, Seyed Mojtaba, Shekar, Kiran, Fraser, John, Smith, Maree T. and Ghassabian, Sussan (2016). High-throughput assay for quantification of the plasma concentrations of thiopental using automated solid phase extraction (SPE) directly coupled to LC–MS/MS instrumentation. Journal of Chromatography B, 1038, 80-87. doi: 10.1016/j.jchromb.2016.10.038

High-throughput assay for quantification of the plasma concentrations of thiopental using automated solid phase extraction (SPE) directly coupled to LC–MS/MS instrumentation

2016

Journal Article

Association between post-sternotomy tracheostomy and deep sternal wound infection: a retrospective analysis

Tsai, Yi-Chin, Phan, Kevin, Stroebel, Andrie, Williams, Livia, Nicotra, Lisa, Drake, Lesley, Ryan, Elizabeth, McGree, James, Tesar, Peter and Shekar, Kiran (2016). Association between post-sternotomy tracheostomy and deep sternal wound infection: a retrospective analysis. Journal of Thoracic Disease, 8 (11), 3294-3300. doi: 10.21037/jtd.2016.11.70

Association between post-sternotomy tracheostomy and deep sternal wound infection: a retrospective analysis

2016

Journal Article

Low preoperative selenium is associated with post-operative atrial fibrillation in patients having intermediate-risk coronary artery surgery

McDonald, C., Fraser, J., Shekar, K., Clarke, A., Coombes, J., Barnett, A., Pearse, B. and Fung, L. (2016). Low preoperative selenium is associated with post-operative atrial fibrillation in patients having intermediate-risk coronary artery surgery. European Journal of Clinical Nutrition, 70 (10), 1138-1143. doi: 10.1038/ejcn.2016.125

Low preoperative selenium is associated with post-operative atrial fibrillation in patients having intermediate-risk coronary artery surgery

2016

Journal Article

Mechanical circulatory support in the new era: an overview

Shekar, Kiran, Gregory, Shaun D. and Fraser, John F. (2016). Mechanical circulatory support in the new era: an overview. Critical Care, 20 (1) 66, 66.1-66.12. doi: 10.1186/s13054-016-1235-3

Mechanical circulatory support in the new era: an overview

2016

Journal Article

Effects of volume resuscitation on the microcirculation in animal models of lipopolysaccharide sepsis: a systematic review

Obonyo, Nchafatso G., Fanning, Jonathon P., Ng, Angela S. Y., Pimenta, Leticia P., Shekar, Kiran, Platts, David G., Maitland, Kathryn and Fraser, John F. (2016). Effects of volume resuscitation on the microcirculation in animal models of lipopolysaccharide sepsis: a systematic review. Intensive Care Medicine Experimental, 4 (1) 38, 1-16. doi: 10.1186/s40635-016-0112-3

Effects of volume resuscitation on the microcirculation in animal models of lipopolysaccharide sepsis: a systematic review