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2016

Journal Article

The complex relationship of extracorporeal membrane oxygenation and acute kidney injury: causation or association?

Kilburn, Daniel J., Shekar, Kiran and Fraser, John F. (2016). The complex relationship of extracorporeal membrane oxygenation and acute kidney injury: causation or association?. BioMed Research International, 2016 1094296, 1094296-14. doi: 10.1155/2016/1094296

The complex relationship of extracorporeal membrane oxygenation and acute kidney injury: causation or association?

2015

Journal Article

Can physicochemical properties of antimicrobials be used to predict their pharmacokinetics during extracorporeal membrane oxygenation? Illustrative data from ovine models

Shekar, Kiran, Roberts, Jason A., Barnett, Adrian G., Diab, Sara, Wallis, Steven C., Fung, Yoke L. and Fraser, John F. (2015). Can physicochemical properties of antimicrobials be used to predict their pharmacokinetics during extracorporeal membrane oxygenation? Illustrative data from ovine models. Critical Care, 19 (1) 437, 1-11. doi: 10.1186/s13054-015-1151-y

Can physicochemical properties of antimicrobials be used to predict their pharmacokinetics during extracorporeal membrane oxygenation? Illustrative data from ovine models

2015

Journal Article

Ovine platelet function is unaffected by extracorporeal membrane oxygenation within the first 24 h

Hayes, Rylan A., Foley, Samuel, Shekar, Kiran, Diab, Sara, Dunster, Kimble R., McDonald, Charles and Fraser, John F. (2015). Ovine platelet function is unaffected by extracorporeal membrane oxygenation within the first 24 h. Blood Coagulation and Fibrinolysis, 26 (7), 816-822. doi: 10.1097/MBC.0000000000000360

Ovine platelet function is unaffected by extracorporeal membrane oxygenation within the first 24 h

2015

Journal Article

Successful conservative management of an iatrogenic ECMO cannula--related inferior vena cava injury

Bhaskar, B., Mullany, D., Parmar, D., Ziengenfuss, M. and Shekar, K. (2015). Successful conservative management of an iatrogenic ECMO cannula--related inferior vena cava injury. Anaesthesia and Intensive Care, 43 (3), 418-419.

Successful conservative management of an iatrogenic ECMO cannula--related inferior vena cava injury

2015

Journal Article

Protein-bound drugs are prone to sequestration in the extracorporeal membrane oxygenation circuit: Results from an ex vivo study

Shekar, Kiran, Roberts, Jason A, Mcdonald, Charles I, Ghassabian, Sussan, Anstey, Chris, Wallis, Steven C, Mullany, Daniel V, Fung, Yoke L and Fraser, John F (2015). Protein-bound drugs are prone to sequestration in the extracorporeal membrane oxygenation circuit: Results from an ex vivo study. Critical Care, 19 (164) 164, 164. doi: 10.1186/s13054-015-0891-z

Protein-bound drugs are prone to sequestration in the extracorporeal membrane oxygenation circuit: Results from an ex vivo study

2015

Journal Article

The impact of acute lung injury, ECMO and transfusion on oxidative stress and plasma selenium levels in an ovine model

McDonald, Charles I, Fung, Yoke Lin, Shekar, Kiran, Diab, Sara D, Dunster, Kimble R, Passmore, Margaret R, Foley, Samuel R, Simonova, Gabriela, Platts, David and Fraser, John F (2015). The impact of acute lung injury, ECMO and transfusion on oxidative stress and plasma selenium levels in an ovine model. Journal of Trace Elements in Medicine and Biology, 30, 4-10. doi: 10.1016/j.jtemb.2015.01.004

The impact of acute lung injury, ECMO and transfusion on oxidative stress and plasma selenium levels in an ovine model

2015

Journal Article

Feasibility of perflutren microsphere contrast transthoracic echocardiography in the visualization of ventricular endocardium during venovenous extracorporeal membrane oxygenation in a validated ovine model

Platts, David G., Diab, Sara, Dunster, Kimble R., Shekar, Kiran, Burstow, Darryl J., Sim, Beatrice, Tunbridge, Matthew, McDonald, Charles, Chemonges, Saul, Chan, Jonathan and Fraser, John F. (2015). Feasibility of perflutren microsphere contrast transthoracic echocardiography in the visualization of ventricular endocardium during venovenous extracorporeal membrane oxygenation in a validated ovine model. Echocardiography, 32 (3), 548-556. doi: 10.1111/echo.12695

Feasibility of perflutren microsphere contrast transthoracic echocardiography in the visualization of ventricular endocardium during venovenous extracorporeal membrane oxygenation in a validated ovine model

2015

Journal Article

Use of extracorporeal membrane oxygenation for mechanical circulatory support in a patient with 5-fluorouracil induced acute heart failure

Rateesh, Shruti, Shekar, Kiran, Naidoo, Rishendran, Mittal, Dolly and Bhaskar, Balu (2015). Use of extracorporeal membrane oxygenation for mechanical circulatory support in a patient with 5-fluorouracil induced acute heart failure. Circulation: Heart Failure, 8 (2), 381-383. doi: 10.1161/CIRCHEARTFAILURE.115.002080

Use of extracorporeal membrane oxygenation for mechanical circulatory support in a patient with 5-fluorouracil induced acute heart failure

2014

Journal Article

The combined effects of extracorporeal membrane oxygenation and renal replacement therapy on meropenem pharmacokinetics: a matched cohort study

Shekar, Kiran, Fraser, John F., Taccone, Fabio Silvio, Welch, Susan, Wallis, Steven C., Mullany, Daniel V., Lipman, Jeffrey and Roberts, Jason A. (2014). The combined effects of extracorporeal membrane oxygenation and renal replacement therapy on meropenem pharmacokinetics: a matched cohort study. Critical Care, 18 (6) 565, 1-9. doi: 10.1186/s13054-014-0565-2

The combined effects of extracorporeal membrane oxygenation and renal replacement therapy on meropenem pharmacokinetics: a matched cohort study

2014

Journal Article

Reduced radiation tolerance of penile structures associated with dose-escalated hypofractionated prostate radiotherapy

McDonald, Andrew M., Baker, Christopher B., Shekar, Kiran, Popple, Richard A., Clark, Grant M., Yang, Eddy S., Jacob, Rojymon, Kim, Robert Y. and Fiveash, John B. (2014). Reduced radiation tolerance of penile structures associated with dose-escalated hypofractionated prostate radiotherapy. Urology, 84 (6), 1383-1388. doi: 10.1016/j.urology.2014.07.060

Reduced radiation tolerance of penile structures associated with dose-escalated hypofractionated prostate radiotherapy

2014

Journal Article

Vancomycin population pharmacokinetics during extracorporeal membrane oxygenation therapy: a matched cohort study

Donadello, Katia, Roberts, Jason A., Cristallini, Stefano, Beumier, Marjorie, Shekar, Kiran, Jacobs, Frederique, Belhaj, Asmae, Vincent, Jean-Louis, de Backer, Daniel and Taccone, Fabio Silvio (2014). Vancomycin population pharmacokinetics during extracorporeal membrane oxygenation therapy: a matched cohort study. Critical Care, 18 (632) 632, 1-10. doi: 10.1186/s13054-014-0632-8

Vancomycin population pharmacokinetics during extracorporeal membrane oxygenation therapy: a matched cohort study

2014

Journal Article

Macro- and micronutrient disposition in an ex vivo model of extracorporeal membrane oxygenation

Estensen, Kristine, Shekar, Kiran, Robins, Elissa, McDonald, Charles, Barnett, Adrian G. and Fraser, John F. (2014). Macro- and micronutrient disposition in an ex vivo model of extracorporeal membrane oxygenation. Intensive Care Medicine Experimental, 2 (1) 29, 29. doi: 10.1186/s40635-014-0029-7

Macro- and micronutrient disposition in an ex vivo model of extracorporeal membrane oxygenation

2014

Journal Article

PC6 acupoint stimulation for the prevention of postcardiac surgery nausea and vomiting: a protocol for a two-group, parallel, superiority randomised clinical trial

Cooke, Marie, Rickard, Claire, Rapchuk, Ivan, Shekar, Kiran, Marshall, Andrea P., Comans, Tracy, Doi, Suhail, McDonald, John and Spooner, Amy (2014). PC6 acupoint stimulation for the prevention of postcardiac surgery nausea and vomiting: a protocol for a two-group, parallel, superiority randomised clinical trial. BMJ Open, 4 (11) 006179, 1-6. doi: 10.1136/bmjopen-2014-006179

PC6 acupoint stimulation for the prevention of postcardiac surgery nausea and vomiting: a protocol for a two-group, parallel, superiority randomised clinical trial

2014

Journal Article

The rapidly evolving use of extracorporeal life support (ECLS) in adults

Mullany, Dan, Shekar, Kiran, Platts, David and Fraser, John (2014). The rapidly evolving use of extracorporeal life support (ECLS) in adults. Heart, Lung and Circulation, 23 (11), 1091-1092. doi: 10.1016/j.hlc.2014.04.009

The rapidly evolving use of extracorporeal life support (ECLS) in adults

2014

Journal Article

Can timely ECMO initiation mitigate pre-ECMO risk factors for acute kidney injury?

Shekar, Kiran and Fraser, John F. (2014). Can timely ECMO initiation mitigate pre-ECMO risk factors for acute kidney injury?. Annals of Thoracic Surgery, 98 (4), 1523-1523. doi: 10.1016/j.athoracsur.2014.05.055

Can timely ECMO initiation mitigate pre-ECMO risk factors for acute kidney injury?

2014

Journal Article

ARDS: rest the lungs or the ventilator?

Shekar, Kiran (2014). ARDS: rest the lungs or the ventilator?. Intensive Care Medicine, 40 (8), 1184-1184. doi: 10.1007/s00134-014-3386-5

ARDS: rest the lungs or the ventilator?

2014

Journal Article

Different rectal toxicity tolerance with and without simultaneous conventionally-fractionated pelvic lymph node treatment in patients receiving hypofractionated prostate radiotherapy

McDonald, Andrew M, Baker, Christopher B, Popple, Richard A, Shekar, Kiran, Yang, Eddy S, Jacob, Rojymon, Cardan, Rex, Kim, Robert Y and Fiveash, John B (2014). Different rectal toxicity tolerance with and without simultaneous conventionally-fractionated pelvic lymph node treatment in patients receiving hypofractionated prostate radiotherapy. Radiation oncology (London, England), 9 (1) 129, 129. doi: 10.1186/1748-717X-9-129

Different rectal toxicity tolerance with and without simultaneous conventionally-fractionated pelvic lymph node treatment in patients receiving hypofractionated prostate radiotherapy

2014

Journal Article

An age-of-blood transfusion trial in the trauma setting is crucial and animal models may help inform trial design

Milford, Elissa M., Reade, Michael C., Colone, Lieutenant, Shekar, Kiran, Tung, John-Paul and Fraser, John F. (2014). An age-of-blood transfusion trial in the trauma setting is crucial and animal models may help inform trial design. Critical Care and Resuscitation, 16 (2), 149-150.

An age-of-blood transfusion trial in the trauma setting is crucial and animal models may help inform trial design

2014

Journal Article

Extracorporeal life support devices and strategies for management of acute cardiorespiratory failure in adult patients: A comprehensive review

Shekar, Kiran, Mullany, Daniel V., Thomson, Bruce, Ziegenfuss, Marc, Platts, David G. and Fraser, John F. (2014). Extracorporeal life support devices and strategies for management of acute cardiorespiratory failure in adult patients: A comprehensive review. Critical Care, 18 (2) 219. doi: 10.1186/cc13865

Extracorporeal life support devices and strategies for management of acute cardiorespiratory failure in adult patients: A comprehensive review

2014

Journal Article

Optimal management of the critically ill: anaesthesia, monitoring, data capture, and point-of-care technological practices in ovine models of critical care

Chemonges, Saul, Shekar, Kiran, Tung, John-Paul, Dunster, Kimble R., Diab, Sara, Platts, David, Watts, Ryan P., Gregory, Shaun D., Foley, Samuel, Simonova, Gabriela, McDonald, Charles, Hayes, Rylan, Bellpart, Judith, Timms, Daniel, Chew, Michelle, Fung, Yoke L., Toon, Michael, Maybauer, Marc O. and Fraser, John F. (2014). Optimal management of the critically ill: anaesthesia, monitoring, data capture, and point-of-care technological practices in ovine models of critical care. BioMed Research International, 2014 (468309) 468309, 1-17. doi: 10.1155/2014/468309

Optimal management of the critically ill: anaesthesia, monitoring, data capture, and point-of-care technological practices in ovine models of critical care