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2014

Journal Article

Ventilator-induced lung injury

Shekar, Kiran and Fraser, John F. (2014). Ventilator-induced lung injury. New England Journal of Medicine, 370 (10), 979-979. doi: 10.1056/NEJMc1400293

Ventilator-induced lung injury

2014

Journal Article

Extracorporeal respiratory support: breaking conventions?

Shekar, K (2014). Extracorporeal respiratory support: breaking conventions?. Anaesthesia and intensive care, 42 (2), 175-7. doi: 10.1177/0310057X1404200202

Extracorporeal respiratory support: breaking conventions?

2014

Journal Article

A novel echocardiographic imaging technique, intracatheter echocardiography, to guide veno-venous extracorporeal membrane oxygenation cannulae placement in a validated ovine model

Platts, David G., Hilton, Andrew, Diab, Sara, McDonald, Charles, Tunbridge, Matthew, Chemonges, Saul, Dunster, Kimble R., Shekar, Kiran, Burstow, Darryl J. and Fraser, John F. (2014). A novel echocardiographic imaging technique, intracatheter echocardiography, to guide veno-venous extracorporeal membrane oxygenation cannulae placement in a validated ovine model. Intensive Care Medicine Experimental, 2 (2) 2, 1-13. doi: 10.1186/2197-425X-2-2

A novel echocardiographic imaging technique, intracatheter echocardiography, to guide veno-venous extracorporeal membrane oxygenation cannulae placement in a validated ovine model

2014

Journal Article

Transfusion of packed red blood cells reduces selenium levels and increases lipid peroxidation in an in vivo ovine model

McDonald, C. I., Fraser, J. F., Shekar, K., Dunster, K. R., Thom, O. and Fung, Y. L. (2014). Transfusion of packed red blood cells reduces selenium levels and increases lipid peroxidation in an in vivo ovine model. Transfusion Medicine, 24 (1), 50-54. doi: 10.1111/tme.12087

Transfusion of packed red blood cells reduces selenium levels and increases lipid peroxidation in an in vivo ovine model

2014

Journal Article

Methyl-CpG-binding protein 2 (MECP2) mutation type is associated with disease severity in rett syndrome

Cuddapah, Vishnu Anand, Pillai, Rajesh B., Shekar, Kiran V., Lane, Jane B., Motil, Kathleen J., Skinner, Steven A., Tarquinio, Daniel Charles, Glaze, Daniel G., McGwin, Gerald, Kaufmann, Walter E., Percy, Alan K., Neul, Jeffrey L. and Olsen, Michelle L. (2014). Methyl-CpG-binding protein 2 (MECP2) mutation type is associated with disease severity in rett syndrome. Journal of Medical Genetics, 51 (3), 152-158. doi: 10.1136/jmedgenet-2013-102113

Methyl-CpG-binding protein 2 (MECP2) mutation type is associated with disease severity in rett syndrome

2014

Journal Article

A preliminary investigation into adrenal responsiveness and outcomes in patients with cardiogenic shock after acute myocardial infarction

Tol, Maneesha M., Shekar, Kiran, Barnett, Adrian G., McGree, James, McWhinney, Brett C., Ziegenfuss, Marc, Ungerer, Jacobus P. and Fraser, John F. (2014). A preliminary investigation into adrenal responsiveness and outcomes in patients with cardiogenic shock after acute myocardial infarction. Journal of Critical Care, 29 (3), 470.e1-470.e6. doi: 10.1016/j.jcrc.2014.01.020

A preliminary investigation into adrenal responsiveness and outcomes in patients with cardiogenic shock after acute myocardial infarction

2013

Journal Article

Can optimal drug dosing during ECMO improve outcomes?

Shekar, Kiran, Fraser, John F. and Roberts, Jason A. (2013). Can optimal drug dosing during ECMO improve outcomes?. Intensive Care Medicine, 39 (12), 2237-2237. doi: 10.1007/s00134-013-3080-z

Can optimal drug dosing during ECMO improve outcomes?

2013

Journal Article

To ventilate, oscillate, or cannulate?

Shekar, Kiran, Davies, Andrew R., Mullany, Daniel V., Tiruvoipati, Ravindranath and Fraser, John F. (2013). To ventilate, oscillate, or cannulate?. Journal of Critical Care, 28 (5), 655-662. doi: 10.1016/j.jcrc.2013.04.009

To ventilate, oscillate, or cannulate?

2013

Journal Article

Stored blood transfusion induces transient pulmonary arterial hypertension without impairing coagulation in an ovine model of nontraumatic haemorrhage

Fung, Y. L., Tung, J. P., Foley, S. R., Simonova, G., Thom, O., Staib, A., Collier, J., Dunster, K. R., Solano, C., Shekar, K., Chew, M. S. and Fraser, J. F. (2013). Stored blood transfusion induces transient pulmonary arterial hypertension without impairing coagulation in an ovine model of nontraumatic haemorrhage. Vox Sanguinis, 105 (2), 150-158. doi: 10.1111/vox.12032

Stored blood transfusion induces transient pulmonary arterial hypertension without impairing coagulation in an ovine model of nontraumatic haemorrhage

2013

Journal Article

Depletion of myocardial glucose is observed during endotoxaemic but not haemorrhagic shock in a porcine model

Chew M. S., Shekar K., Brand B. A., Norin C. and Barnett A. G. (2013). Depletion of myocardial glucose is observed during endotoxaemic but not haemorrhagic shock in a porcine model. Critical Care, 17 (4) R164. doi: 10.1186/cc12843

Depletion of myocardial glucose is observed during endotoxaemic but not haemorrhagic shock in a porcine model

2013

Journal Article

Is hyperoxaemia helping or hurting patients during extracorporeal membrane oxygenation? Review of a complex problem

Hayes, R. A., Shekar, K. and Fraser, J. F. (2013). Is hyperoxaemia helping or hurting patients during extracorporeal membrane oxygenation? Review of a complex problem. Perfusion, 28 (3), 184-193. doi: 10.1177/0267659112473172

Is hyperoxaemia helping or hurting patients during extracorporeal membrane oxygenation? Review of a complex problem

2013

Journal Article

The ECMO PK Project: an incremental research approach to advance understanding of the pharmacokinetic alterations and improve patient outcomes during extracorporeal membrane oxygenation

Shekar, Kiran, Roberts, Jason A., Smith, Maree T., Fung, Yoke L. and Fraser, John F. (2013). The ECMO PK Project: an incremental research approach to advance understanding of the pharmacokinetic alterations and improve patient outcomes during extracorporeal membrane oxygenation. BMC Anesthesiology, 13 (1) 7, 7.1-7.10. doi: 10.1186/1471-2253-13-7

The ECMO PK Project: an incremental research approach to advance understanding of the pharmacokinetic alterations and improve patient outcomes during extracorporeal membrane oxygenation

2013

Journal Article

Single-centre experience of donation after cardiac death

Kumar, Raj, Shekar, Kiran and Fraser, John F. (2013). Single-centre experience of donation after cardiac death. Medical Journal of Australia, 198 (2), 87-88. doi: 10.5694/mja12.11502

Single-centre experience of donation after cardiac death

2013

Journal Article

Hyperoxic damage and the need for optimised oxygenation practices

Hayes, Rylan A., Shekar, Kiran and Fraser, John F. (2013). Hyperoxic damage and the need for optimised oxygenation practices. Critical Care, 17 (4) 441, 441. doi: 10.1186/cc12802

Hyperoxic damage and the need for optimised oxygenation practices

2012

Journal Article

Massive bilateral pulmonary emboli, paradoxical embolus and the knot of life

Platts, David, Shekar, Kiran, Senz, Ainslie and Thomson, Bruce (2012). Massive bilateral pulmonary emboli, paradoxical embolus and the knot of life. European Heart Journal, 33 (24), 3077-3077. doi: 10.1093/eurheart/ehs256

Massive bilateral pulmonary emboli, paradoxical embolus and the knot of life

2012

Journal Article

Drotrecogin alfa (activated) falls amid continuing enthusiasm to normalise physiology in ICU patients

Shekar, Kiran and Fraser, John F. (2012). Drotrecogin alfa (activated) falls amid continuing enthusiasm to normalise physiology in ICU patients. Critical Care and Resuscitation, 14 (4), 324-324. doi: 10.1016/s1441-2772(23)01775-1

Drotrecogin alfa (activated) falls amid continuing enthusiasm to normalise physiology in ICU patients

2012

Journal Article

ASAP ECMO: antibiotic, sedative and analgesic pharmacokinetics during extracorporeal membrane oxygenation: a multi-centre study to optimise drug therapy during ECMO

Shekar, Kiran, Roberts, Jason A., Welsh, Susan, Buscher, Hergen, Rudham, Sam, Burrows, Fay, Ghassabian, Sussan, Wallis, Steven C., Levkovich, Bianca, Pellegrino, Vin, McGuiness, Shay, Parke, Rachael, Gilder, Eileen, Barnett, Adrian G., Walsham, James, Mullany, Daniel V., Fung, Yoke L., Smith, Maree T. and Fraser, John F. (2012). ASAP ECMO: antibiotic, sedative and analgesic pharmacokinetics during extracorporeal membrane oxygenation: a multi-centre study to optimise drug therapy during ECMO. BMC Anesthesiology, 12 (1) 29, 29.1-29.9. doi: 10.1186/1471-2253-12-29

ASAP ECMO: antibiotic, sedative and analgesic pharmacokinetics during extracorporeal membrane oxygenation: a multi-centre study to optimise drug therapy during ECMO

2012

Journal Article

Sedation during extracorporeal membrane oxygenation-why more is less

Shekar, K., Roberts, J. A., Ghassabian, S., Mullany, D. V., Ziegenfuss, M., Smith, M. T., Fung, Y. L. and Fraser, J. F. (2012). Sedation during extracorporeal membrane oxygenation-why more is less. Anaesthesia and Intensive Care, 40 (6), 1067-1069.

Sedation during extracorporeal membrane oxygenation-why more is less

2012

Journal Article

Altered antibiotic pharmacokinetics during extracorporeal membrane oxygenation: cause for concern?

Shekar, Kiran, Roberts, Jason A., Ghassabian, Sussan, Mullany, Daniel V., Wallis, Steven C., Smith, Maree T. and Fraser, John F. (2012). Altered antibiotic pharmacokinetics during extracorporeal membrane oxygenation: cause for concern?. Journal of Antimicrobial Chemotherapy, 68 (3), 726-727. doi: 10.1093/jac/dks435

Altered antibiotic pharmacokinetics during extracorporeal membrane oxygenation: cause for concern?

2012

Journal Article

Sequestration of drugs in the circuit may lead to therapeutic failure during extracorporeal membrane oxygenation

Shekar, Kiran, Roberts, Jason A., McDonald, Charles I., Fisquet, Stephanie, Barnett, Adrian G., Mullany, Daniel V., Ghassabian, Sussan, Wallis, Steven C., Fung, Yoke L., Smith, Maree T. and Fraser, John F. (2012). Sequestration of drugs in the circuit may lead to therapeutic failure during extracorporeal membrane oxygenation. Critical Care, 16 (5) R194, R194.1-R194.7. doi: 10.1186/cc11679

Sequestration of drugs in the circuit may lead to therapeutic failure during extracorporeal membrane oxygenation