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2010 Journal Article Fragment-based screening by X-ray crystallography, MS and isothermal titration calorimetry to identify PNMT (phenylethanolamine N-methyltransferase) inhibitorsDrinkwater, Nyssa, Vu, Hoan, Lovell, Kimberly M., Criscione, Kevin R., Collins, Brett M., Prisinzano, Thomas E., Pulsen, Sally‑Ann, McLeish, Michael J., Grunewald, Gary L. and Martin, Jennifer L. (2010). Fragment-based screening by X-ray crystallography, MS and isothermal titration calorimetry to identify PNMT (phenylethanolamine N-methyltransferase) inhibitors. Biochemical Journal, 431 (1), 51-61. doi: 10.1042/BJ20100651 |
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2010 Journal Article Characterization of the DsbA oxidative folding catalyst from pseudomonas aerugionsa reveals a highly oxidizing protein that binds small moleculesShouldice, Stephen R., Heras, Begoña, Jarrott, Russell, Sharma, Pooja, Scanlon, Martin J. and Martin, Jennifer L. (2010). Characterization of the DsbA oxidative folding catalyst from pseudomonas aerugionsa reveals a highly oxidizing protein that binds small molecules. Antioxidants and Redox Signaling, 12 (8), 921-931. doi: 10.1089/ars.2009.2736 |
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2010 Journal Article Backbone and side chain H-1, N-15 and C-13 assignments for the oxidised and reduced forms of the oxidoreductase protein DsbA from Staphylococcus aureusWilliams, Martin L., Chalmers, David K., Martin, Jennifer L. and Scanlon, Martin J. (2010). Backbone and side chain H-1, N-15 and C-13 assignments for the oxidised and reduced forms of the oxidoreductase protein DsbA from Staphylococcus aureus. Biomolecular NMR assignments, 4 (1), 25-28. doi: 10.1007/s12104-009-9199-8 |
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2010 Journal Article Solving the alpha-conotoxin folding problem: Efficient selenium-directed on-resin generation of more potent and stable nicotinic acetylcholine receptor antaqonistsMuttenthaler, Marcus, Nevin, Simon T., Grishin, Anton A., Ngo, Shyuan T., Choy, Peng T., Daly, Norelle L., Hu, Shu-Hong, Armishaw, Christopher J., Wang, Ching-I. A., Lewis, Richard J., Martin, Jennifer L., Noakes, Peter G., Craik, David J., Adams, David J. and Alewood, Paul F. (2010). Solving the alpha-conotoxin folding problem: Efficient selenium-directed on-resin generation of more potent and stable nicotinic acetylcholine receptor antaqonists. Journal of the American Chemical Society, 132 (10), 3514-3522. doi: 10.1021/ja910602h |
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2010 Journal Article In vivo oxidative protein folding can be facilitated by oxidation-reduction cyclingShouldice, S. R., Cho, S. H., Boyd, D, Heras, B, Eser, M, Beckwith, J, Riggs, P, Martin, J. L. and Berkmen, M (2010). In vivo oxidative protein folding can be facilitated by oxidation-reduction cycling. Molecular Microbiology, 75 (1), 13-28. doi: 10.1111/j.1365-2958.2009.06952.x |
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2009 Journal Article Interaction between plate make and protein in protein crystallisation screeningKing, Gordon J., Chen, Kai-En, Robin, Gautier, Forwood, Jade K., Heras, Begoña, Thakur, Anil S., Kobe, Bostjan, Blomberg, Simon P. and Martin, Jennifer L. (2009). Interaction between plate make and protein in protein crystallisation screening. PLoS One, 4 (11) e7851, x-x. doi: 10.1371/journal.pone.0007851 |
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2009 Journal Article Structural and functional characterization of the oxidoreductase alpha-DsbA1 from wolbachia pipientisKurz, Mareike, Iturbe-Ormaetxe, Iñaki, Jarrott, Russell, Shouldice, Stephen R., Wouters, Merridee A., Frei, Patrick, Glockshuber, Rudi, O'Neill, Scott L., Heras, Begoña and Martin, Jennifer L. (2009). Structural and functional characterization of the oxidoreductase alpha-DsbA1 from wolbachia pipientis. Antioxidants and Redox Signaling, 11 (7), 1485-1500. doi: 10.1089/ars.2008.2420 |
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2009 Journal Article Molecular recognition of physiological substrate noradrenaline by the adrenaline-synthesizing enzyme PNMT and factors influencing its methyltransferase activityDrinkwater, N, Gee, C. L., Puri, M, Criscione, K. R., McLeish, M. J., Grunewald, G. L. and Martin, J. L. (2009). Molecular recognition of physiological substrate noradrenaline by the adrenaline-synthesizing enzyme PNMT and factors influencing its methyltransferase activity. Biochemical Journal, 422 (3), 463-471. doi: 10.1042/BJ20090702 |
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2009 Journal Article Combined x-ray and NMR analysis of the stability of the cyclotide cystine knot fold that underpins its insecticidal activity and potential use as a drug scaffoldWang, C. K., Hu, S. H., Martin, J. L., Sjogren, T, Hajdu, J, Bohlin, L, Claeson, P, Goransson, U, Rosengren, K. J., Tang, J, Tan, N. H. and Craik, D. J. (2009). Combined x-ray and NMR analysis of the stability of the cyclotide cystine knot fold that underpins its insecticidal activity and potential use as a drug scaffold. Journal of Biological Chemistry, 284 (16), 10672-10683. doi: 10.1074/jbc.M900021200 |
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2009 Journal Article Properties of the thioredoxin fold superfamily are modulated by a single amino acid residueRen, G. P., Stephan, D., Xu, Z. H., Zheng, Y., Tang, D. M., Harrison, R. S., Kurz, M, Jarrott, R, Shouldice, S. R., Hiniker, A., Martin, J. L., Heras, B. and Bardwell, J. C. A. (2009). Properties of the thioredoxin fold superfamily are modulated by a single amino acid residue. Journal of Biological Chemistry, 284 (15), 10150-10159. doi: 10.1074/jbc.M809509200 |
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2009 Journal Article Expression, purification and preliminary X-ray diffraction studies of VERNALIZATION1208–341 from Arabidopsis thalianaKing, Gordon, Hill, Justine M., Martin, Jennifer L. and Mylne, Joshua S. (2009). Expression, purification and preliminary X-ray diffraction studies of VERNALIZATION1208–341 from Arabidopsis thaliana. Acta Crystallographica Section F-Structural Biology and Crystallization Communications, 65 (3), 291-294. doi: 10.1107/S1744309109004217 |
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2009 Journal Article Structure of West Nile virus NS3 protease: Ligand stabilization of the catalytic conformationRobin, Gautier, Chappell, Keith, Stoermer, Martin J., Hu, Shu-Hong, Young, Paul R., Fairlie, David P. and Martin, Jennifer L. (2009). Structure of West Nile virus NS3 protease: Ligand stabilization of the catalytic conformation. Journal of Molecular Biology, 385 (5), 1568-1577. doi: 10.1016/j.jmb.2008.11.026 |
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2008 Journal Article Crystallography and protein-protein interactions: Biological interfaces and crystal contactsKobe, Bostjan, Guncar, Gregor, Buchholz, Rebecca, Huber, Thomas, Maco, Bohumil, Cowieson, Nathan, Martin, Jennifer L., Marfori, Mary and Forwood, Jade K. (2008). Crystallography and protein-protein interactions: Biological interfaces and crystal contacts. Biochemical Society Transactions, 36 (6), 1438-1441. doi: 10.1042/BST0361438 |
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2008 Journal Article United we stand: combining structural methodsCowieson, Nathan P., Kobe, Bostjan and Martin, Jennifer L. (2008). United we stand: combining structural methods. Current Opinion in Structural Biology, 18 (5), 617-622. doi: 10.1016/j.sbi.2008.07.004 |
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2008 Journal Article Increasing protein crystallization screening success with heterogeneous nucleating agentsThakur, Anil S, Newman, Janet, Martin, Jennifer L and Kobe, Bostjan (2008). Increasing protein crystallization screening success with heterogeneous nucleating agents. Methods in molecular biology (Clifton, N.J.), 426, 403-409. doi: 10.1007/978-1-60327-058-8_26 |
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2008 Journal Article Federated repositories of X-ray diffraction imagesAndroulakis, S., Schmidberger, J., Bate, M. A., DeGori, R., Beitz, A., Keong, C., Cameron, B., McGowan, S., Porter, C. J., Harrison, A., Hunter, J., Martin, J. L., Kobe, B., Dobson, R. C. J., Parker, M. W., Whisstock, J. C., Gray, J., Treloar, A., Groenewegen, D., Dickson, N. and Buckle, A. M. (2008). Federated repositories of X-ray diffraction images. Acta Crystallographica Section D: Biological Crystallography, 64 (7), 810-814. doi: 10.1107/S0907444908015540 |
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2008 Journal Article Cortactin adopts a globular conformation and bundles actin into sheetsCowieson, Nathan P., King, Gordon, Cookson, David, Ross, Ian, Huber, Thomas, Hume, David A., Kobe, Bostjan and Martin, Jennifer L. (2008). Cortactin adopts a globular conformation and bundles actin into sheets. The Journal of Biological Chemistry, 283 (23), 16187-16193. doi: 10.1074/jbc.M708917200 |
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2008 Journal Article Cloning, expression, purification and characterization of a DsbA-like protein from Wolbachia pipientisKurz, Mareike, Iturbe-Ormaetxe, Inaki, Jarrott, Russell, Cowieson, Nathan, Robin, Gautier, Jones, Alun, King, Gordon J., Frei, Patrick, Glockshuber, Rudi, O'Neill, Scott L., Heras, Begona and Martin, Jennifer L. (2008). Cloning, expression, purification and characterization of a DsbA-like protein from Wolbachia pipientis. Protein Expression and Purification, 59 (2), 266-273. doi: 10.1016/j.pep.2008.02.008 |
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2008 Journal Article Evaluating protein: Protein complex formation using synchrotron radiation circular dichroism spectroscopyCowieson, Nathan P., Miles, Andrew J., Robin, Gautier, Forwood, Jade K., Kobe, Bostjan, Martin, Jennifer L. and Wallace, B. A. (2008). Evaluating protein: Protein complex formation using synchrotron radiation circular dichroism spectroscopy. Proteins: Structure Function Bioinformatics, 70 (4), 1142-1146. doi: 10.1002/prot.21631 |
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2008 Journal Article Staphylococcus aureus DsbA does not have a destabilizing disulfide: A new paradigm for bacterial oxidative foldingHeras, Begona, Kurz, Mareike, Jarrott, Russell, Shouldice, Stephen R., Frei, Patrick, Robin, Gautier, Cemazar, Masa, Thony-Meyer, Linda, Glockshuber, Rudi and Martin, Jennifer L. (2008). Staphylococcus aureus DsbA does not have a destabilizing disulfide: A new paradigm for bacterial oxidative folding. The Journal of Biological Chemistry, 283 (7), 4261-4271. doi: 10.1074/jbc.M707838200 |
