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2020

Journal Article

Ciliopathies and the kidney: a review

McConnachie, Dominique J., Stow, Jennifer L. and Mallett, Andrew J. (2020). Ciliopathies and the kidney: a review. American Journal of Kidney Diseases, 77 (3), 410-419. doi: 10.1053/j.ajkd.2020.08.012

Ciliopathies and the kidney: a review

2020

Journal Article

Neurotoxic peptides from the venom of the giant Australian stinging tree

Gilding, Edward K., Jami, Sina, Deuis, Jennifer R., Israel, Mathilde R., Harvey, Peta J., Poth, Aaron G., Rehm, Fabian B. H., Stow, Jennifer L., Robinson, Samuel D., Yap, Kuok, Brown, Darren L., Hamilton, Brett R., Andersson, David, Craik, David J., Vetter, Irina and Durek, Thomas (2020). Neurotoxic peptides from the venom of the giant Australian stinging tree. Science Advances, 6 (38) eabb8828, 1-10. doi: 10.1126/sciadv.abb8828

Neurotoxic peptides from the venom of the giant Australian stinging tree

2020

Journal Article

Macropinocytosis: insights from immunology and cancer

Stow, Jennifer L., Hung, Yu and Wall, Adam A. (2020). Macropinocytosis: insights from immunology and cancer. Current Opinion in Cell Biology, 65, 131-140. doi: 10.1016/j.ceb.2020.06.005

Macropinocytosis: insights from immunology and cancer

2020

Journal Article

Editorial overview: Membrane traffic in the time of COVID-19

Brodsky, Frances M. and Stow, Jennifer L. (2020). Editorial overview: Membrane traffic in the time of COVID-19. Current Opinion in Cell Biology, 65, iii-v. doi: 10.1016/j.ceb.2020.09.003

Editorial overview: Membrane traffic in the time of COVID-19

2020

Journal Article

High‐speed squeeze: light‐sheet imaging of zebrafish neutrophils

Stow, Jennifer L. and Condon, Nicholas D. (2020). High‐speed squeeze: light‐sheet imaging of zebrafish neutrophils. Journal of Leukocyte Biology, 108 (2), 447-449. doi: 10.1002/jlb.1ce0320-082

High‐speed squeeze: light‐sheet imaging of zebrafish neutrophils

2020

Journal Article

Toll-like receptor 4 stimulates gene expression via Smad2 linker region phosphorylation in vascular smooth muscle cells

Afroz, Rizwana, Zhou, Ying, Little, Peter J., Xu, Suowen, Mohamed, Raafat, Stow, Jennifer and Kamato, Danielle (2020). Toll-like receptor 4 stimulates gene expression via Smad2 linker region phosphorylation in vascular smooth muscle cells. ACS Pharmacology and Translational Science, 3 (3) acsptsci.9b00113, 524-534. doi: 10.1021/acsptsci.9b00113

Toll-like receptor 4 stimulates gene expression via Smad2 linker region phosphorylation in vascular smooth muscle cells

2020

Journal Article

Class IIa histone deacetylases drive toll-like receptor-inducible glycolysis and macrophage inflammatory responses via pyruvate kinase M2

Das Gupta, Kaustav, Shakespear, Melanie R., Curson, James E.B., Murthy, Ambika M.V., Iyer, Abishek, Hodson, Mark P., Ramnath, Divya, Tillu, Vikas A., von Pein, Jessica B., Reid, Robert C., Tunny, Kathryn, Hohenhaus, Daniel M., Moradi, Shayli Varasteh, Kelly, Gregory M., Kobayashi, Takumi, Gunter, Jennifer H., Stevenson, Alexander J., Xu, Weijun, Luo, Lin, Jones, Alun, Johnston, Wayne A., Blumenthal, Antje, Alexandrov, Kirill, Collins, Brett M., Stow, Jennifer L., Fairlie, David P. and Sweet, Matthew J. (2020). Class IIa histone deacetylases drive toll-like receptor-inducible glycolysis and macrophage inflammatory responses via pyruvate kinase M2. Cell Reports, 30 (8), 2712-2728.e8. doi: 10.1016/j.celrep.2020.02.007

Class IIa histone deacetylases drive toll-like receptor-inducible glycolysis and macrophage inflammatory responses via pyruvate kinase M2

2020

Journal Article

A life in pictures—Marilyn Gist Farquhar

Stow, Jennifer L., Saraste, Jaakko and Brown, William J. (2020). A life in pictures—Marilyn Gist Farquhar. Journal of Cell Biology, 219 (2). doi: 10.1083/jcb.202001010

A life in pictures—Marilyn Gist Farquhar

2020

Journal Article

Automated analysis of cell surface ruffling: ruffle quantification macro

Condon, Nicholas D., Stow, Jennifer L. and Wall, Adam A. (2020). Automated analysis of cell surface ruffling: ruffle quantification macro. Bio-Protocol, 10 (2) e3494, e3494. doi: 10.21769/BioProtoc.3494

Automated analysis of cell surface ruffling: ruffle quantification macro

2019

Journal Article

Signalling, sorting and scaffolding adaptors for Toll-like receptors

Luo, Lin, Lucas, Richard M., Liu, Liping and Stow, Jennifer L. (2019). Signalling, sorting and scaffolding adaptors for Toll-like receptors. Journal of Cell Science, 133 (5) jcs239194, jcs239194. doi: 10.1242/jcs.239194

Signalling, sorting and scaffolding adaptors for Toll-like receptors

2019

Journal Article

SCIMP is a universal Toll‐like receptor adaptor in macrophages

Luo, Lin, Curson, James E. B., Liu, Liping, Wall, Adam A., Tuladhar, Neeraj, Lucas, Richard M., Sweet, Matthew J. and Stow, Jennifer L. (2019). SCIMP is a universal Toll‐like receptor adaptor in macrophages. Journal of Leukocyte Biology, 107 (2) JLB.2MA0819-138RR, 251-262. doi: 10.1002/jlb.2ma0819-138rr

SCIMP is a universal Toll‐like receptor adaptor in macrophages

2019

Journal Article

Inhibitors of class I histone deacetylases attenuate thioacetamide-induced liver fibrosis in mice by suppressing hepatic Type 2 inflammation

Loh, Zhixuan, Fitzsimmons, Rebecca L., Reid, Robert C., Ramnath, Divya, Clouston, Andrew, Gupta, Praveer K., Irvine, Katharine M., Powell, Elizabeth E., Schroder, Kate, Stow, Jennifer L., Sweet, Matthew J., Fairlie, David P. and Iyer, Abishek (2019). Inhibitors of class I histone deacetylases attenuate thioacetamide-induced liver fibrosis in mice by suppressing hepatic Type 2 inflammation. British Journal of Pharmacology, 176 (19) bph.14768, 3775-3790. doi: 10.1111/bph.14768

Inhibitors of class I histone deacetylases attenuate thioacetamide-induced liver fibrosis in mice by suppressing hepatic Type 2 inflammation

2019

Journal Article

RAB27A promotes melanoma cell invasion and metastasis via regulation of pro-invasive exosomes

Guo, Dajiang, Lui, Goldie Y. L., Lai, Siew Li, Wilmott, James S., Tikoo, Shweta, Jackett, Louise A., Quek, Camelia, Brown, Darren L., Sharp, Danae M., Kwan, Rain Y. Q., Chacon, Diego, Wong, Jason H., Beck, Dominik, van Geldermalsen, Michelle, Holst, Jeff, Thompson, John F., Mann, Graham J., Scolyer, Richard A., Stow, Jennifer L., Weninger, Wolfgang, Haass, Nikolas K. and Beaumont, Kimberley A. (2019). RAB27A promotes melanoma cell invasion and metastasis via regulation of pro-invasive exosomes. International Journal of Cancer, 144 (12), 3070-3085. doi: 10.1002/ijc.32064

RAB27A promotes melanoma cell invasion and metastasis via regulation of pro-invasive exosomes

2019

Journal Article

Guanine nucleotide exchange factors activate Rab8a for Toll-like receptor signalling

Tong, Samuel J., Wall, Adam A., Hung, Yu, Luo, Lin and Stow, Jennifer L. (2019). Guanine nucleotide exchange factors activate Rab8a for Toll-like receptor signalling. Small GTPases, 12 (1), 1-17. doi: 10.1080/21541248.2019.1587278

Guanine nucleotide exchange factors activate Rab8a for Toll-like receptor signalling

2019

Journal Article

Rab8a localisation and activation by Toll-like receptors on macrophage macropinosomes

Wall, Adam A., Condon, Nicholas D., Luo, Lin and Stow, Jennifer L. (2019). Rab8a localisation and activation by Toll-like receptors on macrophage macropinosomes. Philosophical Transactions of the Royal Society B: Biological Sciences, 374 (1765) 20180151, 20180151. doi: 10.1098/rstb.2018.0151

Rab8a localisation and activation by Toll-like receptors on macrophage macropinosomes

2019

Journal Article

Individual Smad2 linker region phosphorylation sites determine the expression of proteoglycan and glycosaminoglycan synthesizing genes

Kamato, Danielle, Burch, Micah, Yang, Zhou, Mohamed, Raafat, Stow, Jennifer L., Osman, Narin and Little, Peter J. (2019). Individual Smad2 linker region phosphorylation sites determine the expression of proteoglycan and glycosaminoglycan synthesizing genes. Cellular Signalling, 53, 365-373. doi: 10.1016/j.cellsig.2018.11.005

Individual Smad2 linker region phosphorylation sites determine the expression of proteoglycan and glycosaminoglycan synthesizing genes

2018

Journal Article

Elongator mutation in mice induces neurodegeneration and ataxia-like behavior

Kojic, Marija, Gaik, Monika, Kiska, Bence, Salerno-Kochan, Anna, Hunt, Sarah, Tedoldi, Angelo, Mureev, Sergey, Jones, Alun, Whittle, Belinda, Genovesi, Laura A., Adolphe, Christelle, Brown, Darren L., Stow, Jennifer L., Alexandrov, Kirill, Sah, Pankaj, Glatt, Sebastian and Wainwright, Brandon J. (2018). Elongator mutation in mice induces neurodegeneration and ataxia-like behavior. Nature Communications, 9 (1) 3195, 3195. doi: 10.1038/s41467-018-05765-6

Elongator mutation in mice induces neurodegeneration and ataxia-like behavior

2018

Journal Article

TLR crosstalk activates LRP1 to recruit Rab8a and PI3Kγ for suppression of inflammatory responses

Luo, Lin, Wall, Adam A., Tong, Samuel J., Hung, Yu, Xiao, Zhijian, Tarique, Abdullah A., Sly, Peter D., Fantino, Emmanuelle, Marzolo, María-Paz and Stow, Jennifer L. (2018). TLR crosstalk activates LRP1 to recruit Rab8a and PI3Kγ for suppression of inflammatory responses. Cell Reports, 24 (11), 3033-3044. doi: 10.1016/j.celrep.2018.08.028

TLR crosstalk activates LRP1 to recruit Rab8a and PI3Kγ for suppression of inflammatory responses

2018

Journal Article

Macropinosome formation by tent pole ruffling in macrophages

Condon, Nicholas D., Heddleston, John M., Chew, Teng-Leong, Luo, Lin, McPherson, Peter S., Ioannou, Maria S., Hodgson, Louis, Stow, Jennifer L. and Wall, Adam A. (2018). Macropinosome formation by tent pole ruffling in macrophages. The Journal of Cell Biology, 217 (11), 3873-3885. doi: 10.1083/jcb.201804137

Macropinosome formation by tent pole ruffling in macrophages

2018

Journal Article

Interleukin-1β maturation triggers its relocation to the plasma membrane for gasdermin-D-dependent and -independent secretion

Monteleone, Mercedes, Stanley, Amanda C., Chen, Kaiwen W., Brown, Darren L., Bezbradica, Jelena S., von Pein, Jessica B., Holley, Caroline L., Boucher, Dave, Shakespear, Melanie R., Kapetanovic, Ronan, Rolfes, Verena, Sweet, Matthew J., Stow, Jennifer L. and Schroder, Kate (2018). Interleukin-1β maturation triggers its relocation to the plasma membrane for gasdermin-D-dependent and -independent secretion. Cell Reports, 24 (6), 1425-1433. doi: 10.1016/j.celrep.2018.07.027

Interleukin-1β maturation triggers its relocation to the plasma membrane for gasdermin-D-dependent and -independent secretion