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2017 Journal Article SCIMP is a transmembrane non-TIR TLR adaptor that promotes proinflammatory cytokine production from macrophagesLuo, Lin, Bokil, Nilesh J., Wall, Adam A., Kapetanovic, Ronan, Lansdaal, Natalie M., Marceline, Faustine, Burgess, Belinda J., Tong, Samuel J., Guo, Zhong, Alexandrov, Kirill, Ross, Ian L., Hibbs, Margaret L., Stow, Jennifer L. and Sweet, Matthew J. (2017). SCIMP is a transmembrane non-TIR TLR adaptor that promotes proinflammatory cytokine production from macrophages. Nature Communications, 8 (1) 14133, 14133. doi: 10.1038/ncomms14133 |
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2005 Journal Article A role for the phagosome in cytokine secretionMurray, R. Z., Kay, J. G., Sangermani, D. G. and Stow, J. L. (2005). A role for the phagosome in cytokine secretion. Science, 310 (5753), 1492-1495. doi: 10.1126/science.1120225 |
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2024 Journal Article Exaptation of an evolutionary constraint enables behavioural control over the composition of secreted venom in a giant centipedeSchendel, Vanessa, Hamilton, Brett R., Robinson, Samuel D., Green, Kathryn, Sayre, Marcel E., Brown, Darren, Stow, Jennifer L., Øyen, Jan Philip, Voje, Kjetil L., Millard, S. Sean, Vetter, Irina, Rash, Lachlan D. and Undheim, Eivind A. B. (2024). Exaptation of an evolutionary constraint enables behavioural control over the composition of secreted venom in a giant centipede. Nature Ecology & Evolution, 9 (1), 1-14. doi: 10.1038/s41559-024-02556-9 |
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2024 Journal Article Golgi-localized Ring Finger Protein 121 is necessary for MYCN-driven neuroblastoma tumorigenesisCheung, Belamy B., Mittra, Ritu, Murray, Jayne, Wang, Qian, Seneviratne, Janith A., Raipuria, Mukesh, Wong, Iris Poh Ling, Restuccia, David, Gifford, Andrew, Salib, Alice, Sutton, Selina, Huang, Libby, Ferdowsi, Parisa Vahidi, Tsang, Joanna, Sekyere, Eric, Mayoh, Chelsea, Luo, Lin, Brown, Darren L., Stow, Jennifer L., Zhu, Shizhen, Young, Richard J., Solomon, Benjamin J., Chappaz, Stephane, Kile, Benjamin, Kueh, Andrew, Herold, Marco J., Hilton, Douglas J., Liu, Tao, Norris, Murray D. ... Marshall, Glenn M. (2024). Golgi-localized Ring Finger Protein 121 is necessary for MYCN-driven neuroblastoma tumorigenesis. Communications Biology, 7 (1) 1322, 1322. doi: 10.1038/s42003-024-06899-8 |
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2024 Journal Article New advances in innate immune endosomal traffickingStocks, Claudia J., Li, Xichun and Stow, Jennifer L. (2024). New advances in innate immune endosomal trafficking. Current Opinion in Cell Biology, 89 102395. doi: 10.1016/j.ceb.2024.102395 |
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2024 Journal Article Azithromycin Augments Bacterial Uptake and Anti-Inflammatory Macrophage Polarization in Cystic FibrosisTarique, Abdullah A., Tuladhar, Neeraj, Kelk, Dean, Begum, Nelufa, Lucas, Richard M., Luo, Lin, Stow, Jennifer L., Wainwright, Claire E., Bell, Scott C., Sly, Peter D. and Fantino, Emmanuelle (2024). Azithromycin Augments Bacterial Uptake and Anti-Inflammatory Macrophage Polarization in Cystic Fibrosis. Cells, 13 (2) 166, 1-13. doi: 10.3390/cells13020166 |
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2023 Journal Article TLR4 phosphorylation at tyrosine 672 activates the ERK/c‐FOS signaling module for LPS‐induced cytokine responses in macrophagesCurson, James E. B., Liu, Liping, Luo, Lin, Muusse, Timothy W., Lucas, Richard M., Gunther, Kimberley S., Vajjhala, Parimala R., Abrol, Rishika, Jones, Alun, Kapetanovic, Ronan, Stacey, Katryn J., Stow, Jennifer L. and Sweet, Matthew J. (2023). TLR4 phosphorylation at tyrosine 672 activates the ERK/c‐FOS signaling module for LPS‐induced cytokine responses in macrophages. European Journal of Immunology, 53 (7) e2250056, e2250056. doi: 10.1002/eji.202250056 |
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2023 Journal Article Macrophage Nrf 2 the rescueStow, Jennifer L. and Sweet, Matthew J. (2023). Macrophage Nrf 2 the rescue. Journal of Cell Biology, 222 (6) e202305036. doi: 10.1083/jcb.202305036 |
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2023 Journal Article HDAC7 is an immunometabolic switch triaging danger signals for engagement of antimicrobial versus inflammatory responses in macrophagesDas Gupta, Kaustav, Ramnath, Divya, von Pein, Jessica B., Curson, James E. B., Wang, Yizhuo, Abrol, Rishika, Kakkanat, Asha, Moradi, Shayli Varasteh, Gunther, Kimberley S., Murthy, Ambika M. V., Stocks, Claudia J., Kapetanovic, Ronan, Reid, Robert C., Iyer, Abishek, Ilka, Zoe C., Nauseef, William M., Plan, Manuel, Luo, Lin, Stow, Jennifer L., Schroder, Kate, Karunakaran, Denuja, Alexandrov, Kirill, Shakespear, Melanie R., Schembri, Mark A., Fairlie, David P. and Sweet, Matthew J. (2023). HDAC7 is an immunometabolic switch triaging danger signals for engagement of antimicrobial versus inflammatory responses in macrophages. Proceedings of the National Academy of Sciences, 120 (4) e2212813120, 1-12. doi: 10.1073/pnas.2212813120 |
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2022 Journal Article ERK1/2 in immune signallingLucas, Richard M., Luo, Lin and Stow, Jennifer L. (2022). ERK1/2 in immune signalling. Biochemical Society Transactions, 50 (5), 1-12. doi: 10.1042/bst20220271 |
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2022 Journal Article Rotational optical tweezers for active microrheometry within living cellsWatson, Mark L., Brown, Darren L., Stilgoe, Alexander B., Stow, Jennifer L. and Rubinsztein-Dunlop, Halina (2022). Rotational optical tweezers for active microrheometry within living cells. Optica, 9 (9), 1066-1072. doi: 10.1364/optica.468713 |
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2022 Journal Article The transmembrane adaptor SCIMP recruits tyrosine kinase Syk to phosphorylate Toll-like receptors to mediate selective inflammatory outputsLiu, Liping, Lucas, Richard M., Nanson, Jeffrey D., Li, Yan, Whitfield, Jason, Curson, James E. B., Tuladhar, Neeraj, Alexandrov, Kirill, Mobli, Mehdi, Sweet, Matthew J., Kobe, Bostjan, Stow, Jennifer and Luo, Lin (2022). The transmembrane adaptor SCIMP recruits tyrosine kinase Syk to phosphorylate Toll-like receptors to mediate selective inflammatory outputs. Journal of Biological Chemistry, 298 (5) 101857, 101857. doi: 10.1016/j.jbc.2022.101857 |
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2022 Journal Article An alternative downstream translation start site in the non‐TIR adaptor Scimp enables selective amplification of CpG DNA responses in mouse macrophagesCurson, James E.B., Luo, Lin, Liu, Liping, Burgess, Belinda J., Bokil, Nilesh J., Wall, Adam A, Brdicka, Tomas, Kapetanovic, Ronan, Stow, Jennifer L and Sweet, Matthew J (2022). An alternative downstream translation start site in the non‐TIR adaptor Scimp enables selective amplification of CpG DNA responses in mouse macrophages. Immunology and Cell Biology, 100 (4), 267-284. doi: 10.1111/imcb.12540 |
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2022 Journal Article Host glycocalyx captures HIV proximal to the cell surface via oligomannose-GlcNAc glycan-glycan interactions to support viral entrySpillings, Belinda L., Day, Christopher J., Garcia-Minambres, Albert, Aggarwal, Anupriya, Condon, Nicholas D., Haselhorst, Thomas, Purcell, Damian F.J., Turville, Stuart G., Stow, Jennifer L., Jennings, Michael P. and Mak, Johnson (2022). Host glycocalyx captures HIV proximal to the cell surface via oligomannose-GlcNAc glycan-glycan interactions to support viral entry. Cell Reports, 38 (5) 110296, 110296. doi: 10.1016/j.celrep.2022.110296 |
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2022 Journal Article Inhibition of the master regulator of Listeria monocytogenes virulence enables bacterial clearance from spacious replication vacuoles in infected macrophagesTran, Thao Thanh, Mathmann, Carmen D., Gatica-Andrades, Marcela, Rollo, Rachel F., Oelker, Melanie, Ljungberg, Johanna K., Nguyen, Tam T. K., Zamoshnikova, Alina, Kummari, Lalith K., Wyer, Orry J. K., Irvine, Katharine M., Melo-Bolívar, Javier, Gross, Annette, Brown, Darren, Mak, Jeffrey Y. W., Fairlie, David P., Hansford, Karl A., Cooper, Matthew A., Giri, Rabina, Schreiber, Veronika, Joseph, Shannon R., Simpson, Fiona, Barnett, Timothy C., Johansson, Jörgen, Dankers, Wendy, Harris, James, Wells, Timothy J., Kapetanovic, Ronan, Sweet, Matthew J. ... Blumenthal, Antje (2022). Inhibition of the master regulator of Listeria monocytogenes virulence enables bacterial clearance from spacious replication vacuoles in infected macrophages. PLoS Pathogens, 18 (1) e1010166, e1010166. doi: 10.1371/journal.ppat.1010166 |
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2021 Journal Article SCIMP is a spatiotemporal transmembrane scaffold for Erk1/2 to direct pro-inflammatory signaling in TLR-activated macrophagesLucas, Richard M., Liu, Liping, Curson, James E. B., Koh, Yvette W. H., Tuladhar, Neeraj, Condon, Nicholas D., Das Gupta, Kaustav, Burgener, Sabrina S., Schroder, Kate, Ingley, Evan, Sweet, Matthew J., Stow, Jennifer L. and Luo, Lin (2021). SCIMP is a spatiotemporal transmembrane scaffold for Erk1/2 to direct pro-inflammatory signaling in TLR-activated macrophages. Cell Reports, 36 (10) 109662, 1-20. doi: 10.1016/j.celrep.2021.109662 |
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2021 Journal Article LLAMA: a robust and scalable machine learning pipeline for analysis of large scale 4D microscopy data: analysis of cell ruffles and filopodiaLefevre, James G., Koh, Yvette W. H., Wall, Adam A., Condon, Nicholas D., Stow, Jennifer L. and Hamilton, Nicholas A. (2021). LLAMA: a robust and scalable machine learning pipeline for analysis of large scale 4D microscopy data: analysis of cell ruffles and filopodia. BMC Bioinformatics, 22 (1) 410, 1-26. doi: 10.1186/s12859-021-04324-z |
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2021 Journal Article Live fluorescence, inverse imaging of cell ruffling, and macropinocytosisKoh, Yvette W. H., Hung, Yu, Tuladhar, Neeraj, Xiao, Zhijian, Brown, Darren L., Condon, Nicholas D. and Stow, Jennifer L. (2021). Live fluorescence, inverse imaging of cell ruffling, and macropinocytosis. Journal of Visualized Experiments (174) e62870. doi: 10.3791/62870 |
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2021 Journal Article A Leep1 into migration and macropinocytosisKoh, Yvette W.H. and Stow, Jennifer L. (2021). A Leep1 into migration and macropinocytosis. Journal of Cell Biology, 220 (7) e202105141, 1-2. doi: 10.1083/jcb.202105141 |
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2021 Journal Article Rab6b localizes to the Golgi complex in murine macrophages and promotes tumor necrosis factor release in response to mycobacterial infectionDomínguez Cadena, Leslie C., Schultz, Thomas E., Zamoshnikova, Alina, Donovan, Meg L., Mathmann, Carmen D., Yu, Chien-Hsiung, Mori, Giorgia, Stow, Jennifer L and Blumenthal, Antje (2021). Rab6b localizes to the Golgi complex in murine macrophages and promotes tumor necrosis factor release in response to mycobacterial infection. Immunology and Cell Biology, 99 (10), 1067-1076. doi: 10.1111/imcb.12503 |
