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2008

Journal Article

Re-engineering of CYP2C9 to probe acid-base substrate selectivity

Tai, Guoying, Dickmann, Leslie J., Matovic, Nicholas, DeVoss, James J., Gillam, Elizabeth M. J. and Rettie, Allan E. (2008). Re-engineering of CYP2C9 to probe acid-base substrate selectivity. Drug Metabolism and Disposition, 36 (10), 1992-1997. doi: 10.1124/dmd.108.022186

Re-engineering of CYP2C9 to probe acid-base substrate selectivity

2008

Journal Article

The critical role of substrate-protein hydrogen bonding in the control of regioselective hydroxylation in P450cin

Meharenna, YT, Slessor, KE, Cavaignac, SM, Poulos, TL and De Voss, JJ (2008). The critical role of substrate-protein hydrogen bonding in the control of regioselective hydroxylation in P450cin. Journal of Biological Chemistry, 283 (16), 10804-10812. doi: 10.1074/jbc.M709722200

The critical role of substrate-protein hydrogen bonding in the control of regioselective hydroxylation in P450cin

2008

Journal Article

Steroidal saponins from the roots of Asparagus racemosus

Hayes, P., Jahidin, A., Lehmann, R., Penman, K., Kitching, W. and De Voss, J. (2008). Steroidal saponins from the roots of Asparagus racemosus. Phytochemistry, 69 (3), 796-804. doi: 10.1016/j.phytochem.2007.09.001

Steroidal saponins from the roots of Asparagus racemosus

2008

Journal Article

Quantitative whole-cell cytochrome P450 measurement suitable for high-throughput application

Johnston, Wayne A., Huang, Weiliang, De Voss, James J., Hayes, Martin A. and Gillam, Elizabeth M.J. (2008). Quantitative whole-cell cytochrome P450 measurement suitable for high-throughput application. Journal of Biomolecular Screening, 13 (2), 135-141. doi: 10.1177/1087057107312780

Quantitative whole-cell cytochrome P450 measurement suitable for high-throughput application

2008

Journal Article

The role of the conserved threonine in P450BM3 oxygen activation: Substrate-determined hydroxylation activity of the Thr268Ala mutant

Cryle, Max J. and De Voss, James J. (2008). The role of the conserved threonine in P450BM3 oxygen activation: Substrate-determined hydroxylation activity of the Thr268Ala mutant. ChemBioChem, 9 (2), 261-266. doi: 10.1002/cbic.200700537

The role of the conserved threonine in P450BM3 oxygen activation: Substrate-determined hydroxylation activity of the Thr268Ala mutant

2007

Journal Article

Complete 1H and 13C assignments of the four major saponins from Dioscorea villosa (wild yam)

Hayes, Patricia Y., Lambert, Lynette K., Lehmann, Reg, Penman, Kerry, Kitching, William and De Voss, James J. (2007). Complete 1H and 13C assignments of the four major saponins from Dioscorea villosa (wild yam). Magnetic Resonance in Chemistry, 45 (11), 1001-1005. doi: 10.1002/mrc.2071

Complete 1H and 13C assignments of the four major saponins from Dioscorea villosa (wild yam)

2007

Journal Article

A shuffled CYP1A library shows both structural integrity and functional diversity

Johnston, Wayne A., Huang, Weiliang, De Voss, James J., Hayes, Martin A. and Gillam, Elizabeth M.J. (2007). A shuffled CYP1A library shows both structural integrity and functional diversity. Drug Metabolism And Disposition, 35 (12), 2177-2185. doi: 10.1124/dmd.107.017939

A shuffled CYP1A library shows both structural integrity and functional diversity

2007

Journal Article

A shuffled CYP2C library with a high degree of structural integrity and functional versatility

Huang, Weiliang, Johnston, Wayne A., Hayes, Martin A., De Voss, James J. and Gillam, Elizabeth M.J. (2007). A shuffled CYP2C library with a high degree of structural integrity and functional versatility. Archives of Biochemistry And Biophysics, 467 (2), 193-205. doi: 10.1016/j.abb.2007.08.023

A shuffled CYP2C library with a high degree of structural integrity and functional versatility

2007

Journal Article

Functional expression and characterization of cytochrome P450 52A21 from Candida albicans

Kim, Donghak, Cryle, Max J., De Voss, James J. and de Montellano, Paul R. Ortiz (2007). Functional expression and characterization of cytochrome P450 52A21 from Candida albicans. Archives of Biochemistry And Biophysics, 464 (2), 213-220. doi: 10.1016/j.abb.2007.02.032

Functional expression and characterization of cytochrome P450 52A21 from Candida albicans

2007

Journal Article

Facile determination of the absolute stereochemistry of hydroxy fatty acids by GC: application to the analysis of fatty acid oxidation by a P450(BM3) mutant

Cryle, Max J. and De Voss, James J. (2007). Facile determination of the absolute stereochemistry of hydroxy fatty acids by GC: application to the analysis of fatty acid oxidation by a P450(BM3) mutant. Tetrahedron: Asymmetry, 18 (4), 547-551. doi: 10.1016/j.tetasy.2007.01.034

Facile determination of the absolute stereochemistry of hydroxy fatty acids by GC: application to the analysis of fatty acid oxidation by a P450(BM3) mutant

2007

Journal Article

Synthesis and absolute configuration of a constitutionally-new [5.6] spiroacetal from B. tryoni (Queensland fruit fly)

Booth, Yvonne K., Hayes, Patricia Y., Moore, Christopher J., Lambert, Lynette K., Kitching, William and De Voss, James J. (2007). Synthesis and absolute configuration of a constitutionally-new [5.6] spiroacetal from B. tryoni (Queensland fruit fly). Organic & Biomolecular Chemistry, 5 (7), 1111-1117. doi: 10.1039/b701833a

Synthesis and absolute configuration of a constitutionally-new [5.6] spiroacetal from B. tryoni (Queensland fruit fly)

2007

Journal Article

Extending the diversity of cytochrome P450 enzymes by DNA family shuffling

Rosic, Nedeljka N., Huang, Weiliang, Johnston, Wayne A., DeVoss, James J. and Gillam, Elizabeth M.J. (2007). Extending the diversity of cytochrome P450 enzymes by DNA family shuffling. Gene, 395 (1-2), 40-48. doi: 10.1016/j.gene.2007.01.031

Extending the diversity of cytochrome P450 enzymes by DNA family shuffling

2007

Journal Article

The stereochemistry of fatty acid hydroxylation by cytochrome P450(BM3)

Cryle, Max J., Matovic, Nick J. and De Voss, James J. (2007). The stereochemistry of fatty acid hydroxylation by cytochrome P450(BM3). Tetrahedron Letters, 48 (1), 133-136. doi: 10.1016/j.tetlet.2006.10.136

The stereochemistry of fatty acid hydroxylation by cytochrome P450(BM3)

2007

Journal Article

Stereoselective synthesis, natural occurrence and CB2 receptor binding affinities of alkylamides from herbal medicines such as Echinacea sp.

Matovic, N., Matthias, A., Gertsch, J., Raduner, S., Bone, K. M., Lehmann, R. P. and DeVoss, J. J. (2007). Stereoselective synthesis, natural occurrence and CB2 receptor binding affinities of alkylamides from herbal medicines such as Echinacea sp.. Organic & Biomolecular Chemistry, 5 (1), 169-174. doi: 10.1039/b615487e

Stereoselective synthesis, natural occurrence and CB2 receptor binding affinities of alkylamides from herbal medicines such as Echinacea sp.

2006

Journal Article

Is the ferric hydroperoxy species responsible for sulfur oxidation in cytochrome P450s?

Cryle, Max J. and De Voss, James J. (2006). Is the ferric hydroperoxy species responsible for sulfur oxidation in cytochrome P450s?. Angewandte Chemie International Edition, 45 (48), 8221-8223. doi: 10.1002/anie.200603411

Is the ferric hydroperoxy species responsible for sulfur oxidation in cytochrome P450s?

2006

Journal Article

RP-HPLC detection of a sulphiting-induced artefact from paeoniflorin in dried roots of Paeonia lactiflora

Hayes, P. Y., Lehmann, R., Penman, K., Bone, K. M., Kitching, W. and De Voss, J. J. (2006). RP-HPLC detection of a sulphiting-induced artefact from paeoniflorin in dried roots of Paeonia lactiflora. Phytochemical Analysis, 17 (4), 251-254. doi: 10.1002/pca.911

RP-HPLC detection of a sulphiting-induced artefact from paeoniflorin in dried roots of Paeonia lactiflora

2006

Journal Article

Bilberry adulteration using the food dye amaranth

Penman, K. G., Halstead, C. W., Matthias, A., De Voss, J. J., Stuthe, J. M. U., Bone, K. M. and Lehmann, R. P. (2006). Bilberry adulteration using the food dye amaranth. Journal of Agricultural and Food Chemistry, 54 (19), 7378-7382. doi: 10.1021/jf061387d

Bilberry adulteration using the food dye amaranth

2006

Journal Article

Asparinins, asparosides, curillins, curillosides and shavatarins: structural clarification with the isolation of shatavarin V, a new steroidal saponin from the root of Asparagus racemosus

Hayes, P. Y., Jahidin, A. H., Lehmann, R., Penman, K., Kitching, W. and De Voss, J. J. (2006). Asparinins, asparosides, curillins, curillosides and shavatarins: structural clarification with the isolation of shatavarin V, a new steroidal saponin from the root of Asparagus racemosus. Tetrahedron Letters, 47 (-), 8683-8687. doi: 10.1016/j.tetlet.2006.10.030

Asparinins, asparosides, curillins, curillosides and shavatarins: structural clarification with the isolation of shatavarin V, a new steroidal saponin from the root of Asparagus racemosus

2006

Journal Article

Structural revision of shatavarins I and IV, the major components from the roots of Asparagus racemosus

Hayes, P. Y., Jahidin, A. H., Lehmann, R., Penman, K., Kitching, W. and De Voss, J. J. (2006). Structural revision of shatavarins I and IV, the major components from the roots of Asparagus racemosus. Tetrahedron Letters, 47 (39), 6965-6969. doi: 10.1016/j.tetlet.2006.07.121

Structural revision of shatavarins I and IV, the major components from the roots of Asparagus racemosus

2006

Journal Article

Cytochrome P450-mediated metabolism of haloperidol and reduced haloperidol to pyridinium metabolites

Avent, Kathryn M., DeVoss, J. J. and Gillam, Elizabeth M. J. (2006). Cytochrome P450-mediated metabolism of haloperidol and reduced haloperidol to pyridinium metabolites. Chemical Research In Toxicology, 19 (7), 914-920. doi: 10.1021/tx0600090

Cytochrome P450-mediated metabolism of haloperidol and reduced haloperidol to pyridinium metabolites