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2015 Journal Article Large screen approaches to identify novel malaria vaccine candidatesDavies, D Huw, Duffy, Patrick, Bodmer, Jean-Luc, Felgner, Philip L. and Doolan, Denise L. (2015). Large screen approaches to identify novel malaria vaccine candidates. Vaccine, 33 (52), 7496-7505. doi: 10.1016/j.vaccine.2015.09.059 |
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2015 Journal Article Synthesis and characterisation of self-assembled and self-adjuvanting asymmetric multi-epitope lipopeptides of ovalbuminEskandari, Sharareh, Stephenson, Rachel J., Fuaad, Abdullah Ahmad, Apte, Simon H., Doolan, Denise L. and Toth, Istvan (2015). Synthesis and characterisation of self-assembled and self-adjuvanting asymmetric multi-epitope lipopeptides of ovalbumin. Chemistry - A European Journal, 21 (3), 1251-1261. doi: 10.1002/chem.201404997 |
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2015 Journal Article Development of a cytokine-secreting-based assay for the identification, sorting and transcriptomic analysis of polyfunctional human T cellsBurel, Julie G., Apte, Simon H. and Doolan, Denise L. (2015). Development of a cytokine-secreting-based assay for the identification, sorting and transcriptomic analysis of polyfunctional human T cells. European Cytokine Network, 26 (4), 67-72. doi: 10.1684/ecn.2015.0369 |
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2015 Journal Article Of monkeys and men: immunomic profiling of sera from humans and non-human primates resistant to schistosomiasis reveals novel potential vaccine candidatesPearson, Mark S, Becker, Luke, Driguez, Patrick, Young, Neil D, Gaze, Soraya, Mendes, Tiago, Li, Xiao-Hong, Doolan, Denise L, Midzi, Nicholas, Mduluza, Takafira, McManus, Donald P, Wilson, R Alan, Bethony, Jeffrey M, Nausch, Norman, Mutapi, Francisca, Felgner, Philip L and Loukas, Alex (2015). Of monkeys and men: immunomic profiling of sera from humans and non-human primates resistant to schistosomiasis reveals novel potential vaccine candidates. Frontiers in immunology, 6 (MAY) 213, 1-13. doi: 10.3389/fimmu.2015.00213 |
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2015 Journal Article Probing of a human proteome microarray with a recombinant pathogen protein reveals a novel mechanism by which hookworms suppress B-cell receptor signalingTribolet, Leon, Cantacessi, Cinzia, Pickering, Darren A., Navarro, Severine, Doolan, Denise L., Trieu, Angela, Fei, Huang, Chao, Yang, Hofmann, Andreas, Gasser, Robin B., Giacomin, Paul R. and Loukas, Alex (2015). Probing of a human proteome microarray with a recombinant pathogen protein reveals a novel mechanism by which hookworms suppress B-cell receptor signaling. The Journal of Infectious Diseases, 211 (3), 416-425. doi: 10.1093/infdis/jiu451 |
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2015 Journal Article The case for a rational genome-based vaccine against malariaProietti, Carla and Doolan, Denise L. (2015). The case for a rational genome-based vaccine against malaria. Frontiers in Microbiology, 5 (DEC) 741, 1-19. doi: 10.3389/fmicb.2014.00741 |
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2015 Journal Article Synthesis and characterisation of self-assembled and self-adjuvanting asymmetric multi-epitope lipopeptides of ovalbuminEskandari, Sharareh, Stephenson, Rachel J., Fuaad, Abdullah Ahmad, Apte, Simon H., Doolan, Denise L. and Toth, Istvan (2015). Synthesis and characterisation of self-assembled and self-adjuvanting asymmetric multi-epitope lipopeptides of ovalbumin. Chemistry: A European Journal, 21 (3), 1251-1261. doi: 10.1002/chem.201404997 |
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2015 Journal Article Specific humoral response of hosts with variable schistosomiasis susceptibilityDriguez, Patrick, McWilliam, Hamish E. G., Gaze, Soraya, Piedrafita, David, Pearson, Mark S., Nakajima, Rie, Duke, Mary, Trieu, Angela, Doolan, Denise L., Cardoso, Fernanda C., Jasinskas, Algis, Gobert, Geoffrey N., Felgner, Philip L., Loukas, Alex, Meeusen, Els and McManus, Donald P. (2015). Specific humoral response of hosts with variable schistosomiasis susceptibility. Immunology and Cell Biology, 94 (1), 52-65. doi: 10.1038/icb.2015.61 |
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2015 Journal Article Antibody signatures reflect different disease pathologies in schistosomiasis japonicaDriguez, Patrick, Li, Yuesheng, Gaze, Soraya, Pearson, Mark S., Nakajima, Rie, Trieu, Angela, Doolan, Denise L., Felgner, Philip L., Hou, Xunya, Cardoso, Fernanda C., Jasinskas, Algis, Gobert, Geoffrey, Loukas, Alexander C. and McManus, Donald P. (2015). Antibody signatures reflect different disease pathologies in schistosomiasis japonica. Journal of Infectious Diseases, 213 (1), 122-130. doi: 10.1093/infdis/jiv356 |
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2015 Book Chapter Protein microarrays for parasite antigen discoveryDriguez, Patrick, Doolan, Denise L., Molina, Douglas M., Loukas, Alex, Trieu, Angela, Felgner, Phil L. and McManus, Donald P. (2015). Protein microarrays for parasite antigen discovery. Parasite genomics protocols . (pp. 221-33) edited by Christopher Peacock. Cham, Switzerland: Springer. doi: 10.1007/978-1-4939-1438-8_13 |
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2014 Journal Article An immunomics approach to schistosome antigen discovery: antibody signatures of naturally resistant and chronically infected individuals from endemic areasGaze, Soraya, Driguez, Patrick, Pearson, Mark S., Mendes, Tiago, Doolan, Denise L., Trieu, Angela, McManus, Donald P., Gobert, Geoffrey N., Periago, Maria Victoria, Correa Oliveira, Rodrigo, Cardoso, Fernanda C., Oliveira, Guilherme, Nakajima, Rie, Jasinskas, Al, Hung, Chris, Liang, Li, Pablo, Jozelyn, Bethony, Jeffrey M., Felgner, Philip L. and Loukas, Alex (2014). An immunomics approach to schistosome antigen discovery: antibody signatures of naturally resistant and chronically infected individuals from endemic areas. PLoS Pathogens, 10 (3) e1004033, e1004033.1-e1004033.16. doi: 10.1371/journal.ppat.1004033 |
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2014 Journal Article Genome- and proteome-wide screening strategies for antigen discovery and immunogen designSchussek, Sophie, Trieu, Angela and Doolan, Denise L. (2014). Genome- and proteome-wide screening strategies for antigen discovery and immunogen design. Biotechnology Advances, 32 (2), 403-414. doi: 10.1016/j.biotechadv.2013.12.006 |
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2014 Journal Article Genome-based vaccine design: The promise for malaria and other infectious diseasesDoolan, Denise L., Apte, Simon H. and Proietti, Carla (2014). Genome-based vaccine design: The promise for malaria and other infectious diseases. International Journal for Parasitology, 44 (12), 901-913. doi: 10.1016/j.ijpara.2014.07.010 |
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2013 Journal Article Correction: a novel candidate vaccine for Cytauxzoonosis inferred from comparative apicomplexan genomicsTarigo, Jaime L., Scholl, Elizabeth H., Bird, David McK., Brown, Corrie C., Cohn, Leah A., Dean, Gregg A., Levy, Michael G., Doolan, Denise L., Trieu, Angela, Nordone, Shila K., Felgner, Philip L., Vigil, Adam and Birkenheuer, Adam J. (2013). Correction: a novel candidate vaccine for Cytauxzoonosis inferred from comparative apicomplexan genomics. PLoS One, 8 (10) e71233, 1-9. doi: 10.1371/annotation/943b121e-343b-4df1-a06b-7f8a205a057d |
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2013 Journal Article Highly sensitive quantitative real-time PCR for the detection of Plasmodium liver-stage parasite burden following low-dose sporozoite challengeSchussek, Sophie, Groves, Penny L., Apte, Simon H. and Doolan, Denise L. (2013). Highly sensitive quantitative real-time PCR for the detection of Plasmodium liver-stage parasite burden following low-dose sporozoite challenge. PLoS One, 8 (10) e77811, e77811.1-e77811.10. doi: 10.1371/journal.pone.0077811 |
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2013 Journal Article Immunization with apical membrane antigen 1 confers sterile infection-blocking immunity against Plasmodium sporozoite challenge in a rodent modelSchussek, Sophie, Trieu, Angela, Apte, Simon H., Sidney, John, Sette, Alessandro and Doolan, Denise L. (2013). Immunization with apical membrane antigen 1 confers sterile infection-blocking immunity against Plasmodium sporozoite challenge in a rodent model. Infection and Immunity, 81 (10), 3586-3599. doi: 10.1128/IAI.00544-13 |
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2013 Journal Article Subcutaneous cholera toxin exposure induces potent CD103+ dermal dendritic cell activation and migrationApte, Simon H., Redmond, Andrew M., Groves, Penny L., Schussek, Sophie, Pattinson, David J. and Doolan, Denise L. (2013). Subcutaneous cholera toxin exposure induces potent CD103+ dermal dendritic cell activation and migration. European Journal of Immunology, 43 (10), 2707-2717. doi: 10.1002/eji.201343475 |
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2013 Journal Article A novel candidate vaccine for Cytauxzoonosis inferred from comparative apicomplexan genomicsTarigo, Jaime L., Scholl, Elizabeth H., Bird, David McK, Brown, Corrie C., Cohn, Leah A., Dean, Gregg A., Levy, Michael G., Doolan, Denise L., Trieu, Angela, Nordone, Shila K., Felgner, Philip L., Vigil, Adam and Birkenheuer, Adam J. (2013). A novel candidate vaccine for Cytauxzoonosis inferred from comparative apicomplexan genomics. PLoS One, 8 (8) e71233, 1-9. doi: 10.1371/journal.pone.0071233 |
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2013 Journal Article Identification of minimal human MHC-restricted CD8+ T-cell epitopes within the Plasmodium falciparum circumsporozoite protein (CSP)Sedegah, Martha, Kim, Yohan, Ganeshan, Harini, Huang, Jun, Belmonte, Maria, Abot, Esteban, Banania, Jo Glenna, Farooq, Fouzia, McGrath, Shannon, Peters, Bjoern, Sette, Alessandro, Soisson, Lorraine, Diggs, Carter, Doolan, Denise L, Tamminga, Cindy, Villasante, Eileen, Hollingdale, Michael R and Richie, Thomas L. (2013). Identification of minimal human MHC-restricted CD8+ T-cell epitopes within the Plasmodium falciparum circumsporozoite protein (CSP). Malaria Journal, 12 (1) 185. doi: 10.1186/1475-2875-12-185 |
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2013 Journal Article DNA prime/Adenovirus boost malaria vaccine encoding P. falciparum CSP and AMA1 induces sterile protection associated with cell-mediated immunityChuang, Ilin, Sedegah, Martha, Cicatelli, Susan, Spring, Michele, Polhemus, Mark, Tamminga, Cindy, Patterson, Noelle, Guerrero, Melanie, Bennett, Jason W, McGrath, Shannon, Ganeshan, Harini, Belmonte, Maria, Farooq, Fouzia, Abot, Esteban, Banania, Jo Glenna, Huang, Jun, Newcomer, Rhonda, Rein, Lisa, Litilit, Dianne, Richie, Nancy O, Wood, Chloe, Murphy, Jittawadee, Sauerwein, Robert, Hermsen, Cornelus C, McCoy, Andrea J, Kamau, Edwin, Cummings, James, Komisar, Jack, Sutamihardja, Awalludin ... Richie, Thomas L (2013). DNA prime/Adenovirus boost malaria vaccine encoding P. falciparum CSP and AMA1 induces sterile protection associated with cell-mediated immunity. PLoS One, 8 (2) e55571, 1-15. doi: 10.1371/journal.pone.0055571 |
