|
2017 Journal Article A Plasmodium vivax plasmid DNA- and adenovirus-vectored malaria vaccine encoding blood-stage antigens AMA1 and MSP142 in a prime/boost heterologous immunization regimen partially protects Aotus monkeys against blood-stage challengeObaldia, Nicanor, Stockelman, Michael G., Otero, William, Cockrill, Jennifer A., Ganeshan, Harini, Abot, Esteban N., Zhang, Jianfeng, Limbach, Keith, Charoenvit, Yupin, Doolan, Denise L., Tang, De-Chu C and Richie, Thomas L (2017). A Plasmodium vivax plasmid DNA- and adenovirus-vectored malaria vaccine encoding blood-stage antigens AMA1 and MSP142 in a prime/boost heterologous immunization regimen partially protects Aotus monkeys against blood-stage challenge. Clinical and Vaccine Immunology, 24 (4) e00539, 1-16. doi: 10.1128/CVI.00539-16 |
|
2017 Journal Article Polyfunctional and IFN- monofunctional human CD4 T cell populations are molecularly distinctBurel, Julie G., Apte, Simon H., Groves, Penny L., McCarthy, James S. and Doolan, Denise L. (2017). Polyfunctional and IFN- monofunctional human CD4 T cell populations are molecularly distinct. JCI Insight, 2 (3) e87499, e87499. doi: 10.1172/jci.insight.87499 |
|
2017 Journal Article Recent advances in proteomic applications for schistosomiasis research: potential clinical impactSotillo, Javier, Doolan, Denise and Loukas, Alex (2017). Recent advances in proteomic applications for schistosomiasis research: potential clinical impact. Expert Review of Proteomics, 14 (2), 171-183. doi: 10.1080/14789450.2017.1271327 |
|
2016 Journal Article Plasmodium vivax but not Plasmodium falciparum blood-stage infection in humans is associated with the expansion of a CD8+T cell population with cytotoxic potentialBurel, Julie G., Apte, Simon H., McCarthy, James S. and Doolan, Denise L. (2016). Plasmodium vivax but not Plasmodium falciparum blood-stage infection in humans is associated with the expansion of a CD8+T cell population with cytotoxic potential. PLoS Neglected Tropical Diseases, 10 (12) e0005031, e0005031. doi: 10.1371/journal.pntd.0005031 |
|
2016 Journal Article Mining, visualizing and comparing multidimensional biomolecular data using the Genomics Data Miner (GMine) web-serverProietti, Carla, Zakrzewski, Martha, Watkins, Thomas S., Berger, Bernard, Hasan, Shihab, Ratnatunga, Champa N., Brion, Marie-Jo, Crompton, Peter D., Miles, John J., Doolan, Denise L. and Krause, Lutz (2016). Mining, visualizing and comparing multidimensional biomolecular data using the Genomics Data Miner (GMine) web-server. Scientific Reports, 6 (1) 38178. doi: 10.1038/srep38178 |
|
2016 Journal Article Type I interferons regulate immune responses in humans with blood-stage Plasmodium falciparum infectionde Oca, Marcela Montes, Kumar, Rajiv, Rivera, Fabian de Labastida, Amante, Fiona H., Sheel, Meru, Faleiro, Rebecca J., Bunn, Patrick T., Best, Shannon E., Beattie, Lynette, Ng, Susanna S., Edwards, Chelsea L., Boyle, Glen M., Price, Ric N., Anstey, Nicholas M., Loughland, Jessica R., Burel, Julie, Doolan, Denise L., Haque, Ashraful, McCarthy, James S. and Engwerda, Christian R. (2016). Type I interferons regulate immune responses in humans with blood-stage Plasmodium falciparum infection. Cell Reports, 17 (2), 399-412. doi: 10.1016/j.celrep.2016.09.015 |
|
2016 Journal Article Reduced Plasmodium parasite burden associates with CD38+ CD4+ T cells displaying cytolytic potential and impaired IFN-γ productionBurel, Julie G., Apte, Simon H., Groves, Penny L., Klein, Kerenaftali, McCarthy, James S. and Doolan, Denise L. (2016). Reduced Plasmodium parasite burden associates with CD38+ CD4+ T cells displaying cytolytic potential and impaired IFN-γ production. PLoS Pathogens, 12 (9) e1005839, e1005839. doi: 10.1371/journal.ppat.1005839 |
|
2016 Journal Article Chemically attenuated blood-stage Plasmodium yoelii parasites induce long-lived and strain-transcending protectionRaja, Amber I., Cai, Yeping, Reiman, Jennifer M., Groves, Penny, Chakravarty, Sumana, McPhun, Virginia, Doolan, Denise L., Cockburn, Ian, Hoffman, Stephen L., Stanisic, Danielle I. and Good, Michael F. (2016). Chemically attenuated blood-stage Plasmodium yoelii parasites induce long-lived and strain-transcending protection. Infection and Immunity, 84 (8), 2274-2288. doi: 10.1128/IAI.00157-16 |
|
2016 Journal Article Mosquito bite immunization with radiation-attenuated Plasmodium falciparum sporozoites: safety, tolerability, protective efficacy and humoral immunogenicityHickey, Bradley W, Lumsden, Joanne M, Reyes, Sharina, Sedegah, Martha, Hollingdale, Michael R, Freilich, Daniel A, Luke, Thomas C, Charoenvit, Yupin, Goh, Lucy M, Berzins, Mara P, Bebris, Lolita, Sacci, John B, De La Vega, Patricia, Wang, Ruobing, Ganeshan, Harini, Abot, Esteban N, Carucci, Daniel J, Doolan, Denise L, Brice, Gary T, Kumar, Anita, Aguiar, Joao, Nutman, Thomas B, Leitman, Susan F, Hoffman, Stephen L, Epstein, Judith E and Richie, Thomas L (2016). Mosquito bite immunization with radiation-attenuated Plasmodium falciparum sporozoites: safety, tolerability, protective efficacy and humoral immunogenicity. Malaria Journal, 15 (1) 377, 1-18. doi: 10.1186/s12936-016-1435-y |
|
2016 Journal Article Profoundly reduced CD1c+ myeloid dendritic cell HLA-DR and CD86 expression and increased tumor necrosis factor production in experimental human blood-stage malaria infectionLoughland, Jessica R., Minigo, Gabriela, Burel, Julie, Tipping, Peta E., Piera, Kim A., Amante, Fiona H., Engwerda, Christian R., Good, Michael F., Doolan, Denise L., Anstey, Nicholas M., McCarthy, James S. and Woodberry, Tonia (2016). Profoundly reduced CD1c+ myeloid dendritic cell HLA-DR and CD86 expression and increased tumor necrosis factor production in experimental human blood-stage malaria infection. Infection and Immunity, 84 (5), 1403-1412. doi: 10.1128/IAI.01522-15 |
|
2016 Journal Article Defining the targets of antiparasitic compoundsSkinner-Adams, Tina S., Sumanadasa, Subathdrage D.M., Fisher, Gillian M., Davis, Rohan A., Doolan, Denise L. and Andrews, Katherine T. (2016). Defining the targets of antiparasitic compounds. Drug Discovery Today, 21 (5), 725-39. doi: 10.1016/j.drudis.2016.01.002 |
|
2016 Journal Article Proceedings of the 7th Biannual International Symposium on Nasopharyngeal Carcinoma 2015 : Yogyakarta, Indonesia. 4-6 June 2015Tan, IB, Chang, Ellen T., Chen, Chien-Jen, Hsu, Wan-Lun, Chien, Yin-Chu, Hildesheim, Allan, McKay, James D., Gaborieau, Valerie, Kaderi, Mohamed Arifin Bin, Purnomosari, Dewajani, Voegele, Catherine, LeCalvez-Kelm, Florence, Byrnes, Graham, Brennan, Paul, Devi, Beena, Li, L., Zhang, Y., Fan, Y., Sun, K., Du, Z., Sun, H., Chan, A. T., Tsao, S. W., Zeng, Y. X., Tao, Q., Busson, Pierre, Lhuillier, Claire, Morales, Olivier, Mrizak, Dhafer ... Haryana, Sofia Mubarika (2016). Proceedings of the 7th Biannual International Symposium on Nasopharyngeal Carcinoma 2015 : Yogyakarta, Indonesia. 4-6 June 2015. BMC Proceedings, 10 (S1) 1. doi: 10.1186/s12919-016-0001-5 |
|
2016 Journal Article Immunomics: a 21st century approach to vaccine development for complex pathogensde Sousa, Karina P. and Doolan, Denise L. (2016). Immunomics: a 21st century approach to vaccine development for complex pathogens. Parasitology, 143 (2), 236-244. doi: 10.1017/S0031182015001079 |
|
2016 Journal Article Synthesis of mannosylated lipopeptides with receptor targeting propertiesSedaghat, Bita, Stephenson, Rachel J., Giddam, Ashwini Kumar, Eskandari, Sharareh, Apte, Simon H., Pattinson, David J., Doolan, Denise L. and Toth, Istvan (2016). Synthesis of mannosylated lipopeptides with receptor targeting properties. Bioconjugate Chemistry, 27 (3), 533-548. doi: 10.1021/acs.bioconjchem.5b00547 |
|
2016 Journal Article Systematic evaluation of self-adjuvanting lipopeptide nano-vaccine platforms for the induction of potent CD8+ T-cell responsesApte, Simon H., Stephenson, Rachel J., Simerska, Pavla, Groves, Penny L., Aljohani, Salwa, Eskandari, Sharareh, Toth, Istvan and Doolan, Denise L. (2016). Systematic evaluation of self-adjuvanting lipopeptide nano-vaccine platforms for the induction of potent CD8+ T-cell responses. Nanomedicine, 11 (2), 137-152. doi: 10.2217/nnm.15.184 |
|
2016 Journal Article Synthesis and immunological evaluation of peptide-based vaccine candidates against malariaChandrudu, Saranya, Skwarczynski, Mariusz, Pattinson, David, Apte, Simon H., Doolan, Denise L. and Toth, Istvan (2016). Synthesis and immunological evaluation of peptide-based vaccine candidates against malaria. Biochemical Compounds, 4 (1). doi: 10.7243/2052-9341-4-1 |
|
2016 Journal Article Systems approaches towards molecular profiling of human immunityBurel, Julie G., Apte, Simon H. and Doolan, Denise L. (2016). Systems approaches towards molecular profiling of human immunity. Trends in Immunology, 37 (1), 53-67. doi: 10.1016/j.it.2015.11.006 |
|
2015 Journal Article Large screen approaches to identify novel malaria vaccine candidatesDavies, D Huw, Duffy, Patrick, Bodmer, Jean-Luc, Felgner, Philip L. and Doolan, Denise L. (2015). Large screen approaches to identify novel malaria vaccine candidates. Vaccine, 33 (52), 7496-7505. doi: 10.1016/j.vaccine.2015.09.059 |
|
2015 Journal Article Synthesis and characterisation of self-assembled and self-adjuvanting asymmetric multi-epitope lipopeptides of ovalbuminEskandari, Sharareh, Stephenson, Rachel J., Fuaad, Abdullah Ahmad, Apte, Simon H., Doolan, Denise L. and Toth, Istvan (2015). Synthesis and characterisation of self-assembled and self-adjuvanting asymmetric multi-epitope lipopeptides of ovalbumin. Chemistry - A European Journal, 21 (3), 1251-1261. doi: 10.1002/chem.201404997 |
|
2015 Journal Article Development of a cytokine-secreting-based assay for the identification, sorting and transcriptomic analysis of polyfunctional human T cellsBurel, Julie G., Apte, Simon H. and Doolan, Denise L. (2015). Development of a cytokine-secreting-based assay for the identification, sorting and transcriptomic analysis of polyfunctional human T cells. European Cytokine Network, 26 (4), 67-72. doi: 10.1684/ecn.2015.0369 |
