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2024

Journal Article

Precision-guided treatment in high-risk pediatric cancers

Lau, Loretta M. S., Khuong-Quang, Dong-Anh, Mayoh, Chelsea, Wong, Marie, Barahona, Paulette, Ajuyah, Pamela, Senapati, Akanksha, Nagabushan, Sumanth, Sherstyuk, Alexandra, Altekoester, Ann-Kristin, Fuentes-Bolanos, Noemi A., Yeung, Veronica, Sullivan, Ashleigh, Omer, Natacha, Diamond, Yonatan, Jessop, Sophie, Battaglia, Lauren, Zhukova, Nataliya, Cui, Louise, Lin, Angela, Gifford, Andrew J., Fleuren, Emmy D. G., Dalla-Pozza, Luciano, Moore, Andrew S., Khaw, Seong-Lin, Eisenstat, David D., Gottardo, Nicholas G., Wood, Paul J., Tapp, Heather ... Ziegler, David S. (2024). Precision-guided treatment in high-risk pediatric cancers. Nature Medicine, 30 (7), 1913-1922. doi: 10.1038/s41591-024-03044-0

Precision-guided treatment in high-risk pediatric cancers

2023

Journal Article

A novel transcriptional signature identifies T-cell infiltration in high-risk paediatric cancer

Mayoh, Chelsea, Gifford, Andrew J., Terry, Rachael, Lau, Loretta M S, Wong, Marie, Rao, Padmashree, Shai-Hee, Tyler, Saletta, Federica, Khuong-Quang, Dong-Anh, Qin, Vicky, Mateos, Marion K., Meyran, Deborah, Miller, Katherine E., Yuksel, Aysen, Mould, Emily V A, Bowen-James, Rachel, Govender, Dinisha, Senapati, Akanksha, Zhukova, Nataliya, Omer, Natacha, Dholaria, Hetal, Alvaro, Frank, Tapp, Heather, Diamond, Yonatan, Pozza, Luciano Dalla, Moore, Andrew S., Nicholls, Wayne, Gottardo, Nicholas G., McCowage, Geoffrey ... Ekert, Paul G. (2023). A novel transcriptional signature identifies T-cell infiltration in high-risk paediatric cancer. Genome Medicine, 15 (1) 20, 20. doi: 10.1186/s13073-023-01170-x

A novel transcriptional signature identifies T-cell infiltration in high-risk paediatric cancer

2023

Journal Article

One Hundred Times Better, at Home in Our Own Beds: Implementation of Home Intravenous Hydration After Chemotherapy in Children With Cancer

Orford, Rebekah, Slater, Penelope, Spencer, Brooke, Giarola, Teghan, Nicholls, Wayne, Walker, Rick, Foresto, Steven and Bradford, Natalie (2023). One Hundred Times Better, at Home in Our Own Beds: Implementation of Home Intravenous Hydration After Chemotherapy in Children With Cancer. Journal of Pediatric Hematology/Oncology Nursing, 40 (4), 265-276. doi: 10.1177/27527530221147880

One Hundred Times Better, at Home in Our Own Beds: Implementation of Home Intravenous Hydration After Chemotherapy in Children With Cancer

2022

Journal Article

COVID-19 vaccination in children and adolescents aged 5 years and older undergoing treatment for cancer and non-malignant haematological conditions: Australian and New Zealand Children’s Haematology/Oncology Group consensus statement

Furlong, Eliska, Kotecha, Rishi S, Conyers, Rachel, O'Brien, Tracey A, Hansford, Jordan R, Super, Leanne, Downie, Peter, Eisenstat, David D, Haeusler, Gabrielle, McMullan, Brendan, Phillips, Marianne B, Padhye, Bhavna, Dalla-Pozza, Luciano, Alvaro, Frank, Fraser, Christopher J, Nicholls, Wayne, Clark, Julia E, O'Connor, Matthew, Saxon, Benjamin R, Tapp, Heather, Heath, John, Hunter, Sarah E, Tsui, Karen, Winstanley, Mark, Lyver, Amanda, Best, Emma J, Wadia, Ushma, Yeoh, Daniel, Blyth, Christopher C and Gottardo, Nicholas G (2022). COVID-19 vaccination in children and adolescents aged 5 years and older undergoing treatment for cancer and non-malignant haematological conditions: Australian and New Zealand Children’s Haematology/Oncology Group consensus statement. Medical Journal of Australia, 216 (6), 312-319. doi: 10.5694/mja2.51444

COVID-19 vaccination in children and adolescents aged 5 years and older undergoing treatment for cancer and non-malignant haematological conditions: Australian and New Zealand Children’s Haematology/Oncology Group consensus statement

2022

Journal Article

Laparoscopic resection of a pediatric intestinal leiomyosarcoma

Brough, Dr David, Miller, Dr Greg, Ross, Dr Ian, Nicholls, Dr Wayne and Cavallucci, A/Prof David (2022). Laparoscopic resection of a pediatric intestinal leiomyosarcoma. Journal of Pediatric Surgery Case Reports, 79 102219, 102219. doi: 10.1016/j.epsc.2022.102219

Laparoscopic resection of a pediatric intestinal leiomyosarcoma

2021

Journal Article

Enhancing natural killer cell targeting of pediatric sarcoma

Omer, Natacha, Nicholls, Wayne, Ruegg, Bronte, Souza-Fonseca-Guimaraes, Fernando and Rossi, Gustavo Rodrigues (2021). Enhancing natural killer cell targeting of pediatric sarcoma. Frontiers in Immunology, 12 791206, 791206. doi: 10.3389/fimmu.2021.791206

Enhancing natural killer cell targeting of pediatric sarcoma

2021

Journal Article

Treatment and Outcomes for Central Nervous System Tumors in Australian Adolescents and Young Adults: A Population-Based National Study

Harrup, Rosemary, White, Victoria M., Coory, Michael, Walker, Rick, Anazodo, Antoinette, Skaczkowski, Gemma, Bibby, Helen, Osborn, Michael, Phillips, Marianne B., Conyers, Rachel, Thompson, Kate, Orme, Lisa M., Pinkerton, Ross and Nicholls, Wayne (2021). Treatment and Outcomes for Central Nervous System Tumors in Australian Adolescents and Young Adults: A Population-Based National Study. Journal of Adolescent and Young Adult Oncology, 10 (2), 202-208. doi: 10.1089/jayao.2020.0074

Treatment and Outcomes for Central Nervous System Tumors in Australian Adolescents and Young Adults: A Population-Based National Study

2021

Journal Article

Outcomes by Clinical and Molecular Features in Children With Medulloblastoma Treated With Risk-Adapted Therapy: Results of an International Phase III Trial (SJMB03)

Gajjar, Amar, Robinson, Giles W., Smith, Kyle S., Lin, Tong, Merchant, Thomas E., Chintagumpala, Murali, Mahajan, Anita, Su, Jack, Bouffet, Eric, Bartels, Ute, Schechter, Tal, Hassall, Tim, Robertson, Thomas, Nicholls, Wayne, Gururangan, Sridharan, Schroeder, Kristin, Sullivan, Michael, Wheeler, Greg, Hansford, Jordan R., Kellie, Stewart J., McCowage, Geoffrey, Cohn, Richard, Fisher, Michael J., Krasin, Matthew J., Stewart, Clinton F., Broniscer, Alberto, Buchhalter, Ivo, Tatevossian, Ruth G., Orr, Brent A. ... Northcott, Paul A. (2021). Outcomes by Clinical and Molecular Features in Children With Medulloblastoma Treated With Risk-Adapted Therapy: Results of an International Phase III Trial (SJMB03). Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 39 (7), 822-835. doi: 10.1200/JCO.20.01372

Outcomes by Clinical and Molecular Features in Children With Medulloblastoma Treated With Risk-Adapted Therapy: Results of an International Phase III Trial (SJMB03)

2020

Journal Article

Prevention of occlusion of cEnTral lInes for children with cancer: an implementation study

Ullman, Amanda J., Condon, Paula, Edwards, Rachel, Gibson, Victoria, Takashima, Mari, Schults, Jessica, Dean, Anna, Cattanach, Paula, Nicholls, Wayne, Osborne, Sonya, Rickard, Claire M., Cooke, Marie and Kleidon, Tricia (2020). Prevention of occlusion of cEnTral lInes for children with cancer: an implementation study. Journal of Paediatrics and Child Health, 56 (12), 1875-1884. doi: 10.1111/jpc.15067

Prevention of occlusion of cEnTral lInes for children with cancer: an implementation study

2020

Journal Article

Primitive myxoid mesenchymal tumor of infancy in the orbit: a new location for a rare tumor

Hayes, Rylan A., Nicholls, Wayne, Davies, Janene and Sullivan, Timothy J. (2020). Primitive myxoid mesenchymal tumor of infancy in the orbit: a new location for a rare tumor. Ophthalmic Plastic and Reconstructive Surgery, 36 (4), e91-e93. doi: 10.1097/iop.0000000000001604

Primitive myxoid mesenchymal tumor of infancy in the orbit: a new location for a rare tumor

2020

Journal Article

Pembrolizumab in paediatric patients with advanced melanoma or a PD-L1-positive, advanced, relapsed, or refractory solid tumour or lymphoma (KEYNOTE-051): interim analysis of an open-label, single-arm, phase 1-2 trial

Geoerger, Birgit, Kang, Hyoung Jin, Yalon-Oren, Michal, Marshall, Lynley V., Vezina, Catherine, Pappo, Alberto, Laetsch, Theodore W., Petrilli, Antonio S., Ebinger, Martin, Toporski, Jacek, Glade-Bender, Julia, Nicholls, Wayne, Fox, Elizabeth, DuBois, Steven G., Macy, Margaret E., Cohn, Susan L., Pathiraja, Kumudu, Diede, Scott J., Ebbinghaus, Scot and Pinto, Navin (2020). Pembrolizumab in paediatric patients with advanced melanoma or a PD-L1-positive, advanced, relapsed, or refractory solid tumour or lymphoma (KEYNOTE-051): interim analysis of an open-label, single-arm, phase 1-2 trial. The Lancet Oncology, 21 (1), 121-133. doi: 10.1016/s1470-2045(19)30671-0

Pembrolizumab in paediatric patients with advanced melanoma or a PD-L1-positive, advanced, relapsed, or refractory solid tumour or lymphoma (KEYNOTE-051): interim analysis of an open-label, single-arm, phase 1-2 trial

2019

Journal Article

Management of sarcoma in adolescents and young adults: an Australian population-based study

White, Victoria M., Orme, Lisa M., Skaczkowski, Gemma, Pinkerton, Ross, Coory, Michael, Osborn, Michael, Bibby, Helen, Nicholls, Wayne, Conyers, Rachel, Phillips, Marianne B., Harrup, Rosemary, Walker, Rick, Thompson, Kate and Anazodo, Antoinette (2019). Management of sarcoma in adolescents and young adults: an Australian population-based study. Journal of Adolescent and Young Adult Oncology, 8 (3), 272-280. doi: 10.1089/jayao.2018.0136

Management of sarcoma in adolescents and young adults: an Australian population-based study

2018

Journal Article

Gender differences in doxorubicin pharmacology for subjects with chemosensitive cancers of young adulthood

Liu, Z., Martin, J., Orme, L., Seddon, B., Desai, J., Nicholls, W., Thomson, D., Porter, D., McCowage, G., Underhill, C., Cranswick, N., Michael, M., Zacharin, M., Herschtal, A., Sivasuthan, J. and Thomas, D. M. (2018). Gender differences in doxorubicin pharmacology for subjects with chemosensitive cancers of young adulthood. Cancer Chemotherapy and Pharmacology, 82 (5), 887-898. doi: 10.1007/s00280-018-3683-8

Gender differences in doxorubicin pharmacology for subjects with chemosensitive cancers of young adulthood

2018

Journal Article

Clinical management of Australian adolescents and young adults with acute lymphoblastic and myeloid leukemias: a national population-based study

White, V. M., Skaczkowski, G., Pinkerton, R., Coory, M., Osborn, M., Bibby, H., Nicholls, W., Orme, L. M., Conyers, R., Phillips, M. B., Harrup, R., Walker, R., Thompson, K. and Anazodo, A. (2018). Clinical management of Australian adolescents and young adults with acute lymphoblastic and myeloid leukemias: a national population-based study. Pediatric Blood & Cancer, 65 (11) e27349. doi: 10.1002/pbc.27349

Clinical management of Australian adolescents and young adults with acute lymphoblastic and myeloid leukemias: a national population-based study

2018

Journal Article

Clinical trial participation by adolescents and young adults with cancer: a continued cause for concern?

White, Victoria, Skaczkowski, Gemma, Anazodo, Antoinette, Bibby, Helen, Nicholls, Wayne, Pinkerton, Ross, Thompson, Kate, Orme, Lisa M., Conyers, Rachel, Osborn, Michael, Phillips, Marianne B., Harrup, Rosemary, Walker, Rick and Coory, Michael (2018). Clinical trial participation by adolescents and young adults with cancer: a continued cause for concern?. Seminars in Oncology, 45 (5-6), 275-283. doi: 10.1053/j.seminoncol.2018.04.002

Clinical trial participation by adolescents and young adults with cancer: a continued cause for concern?

2018

Journal Article

Osteogenic sarcoma in an adolescent with cystic fibrosis: successful treatment despite significant obstacles

Ruffles, Thomas J. C., Black, Ryan, Nicholls, Wayne, Laing, Barbara and Isles, Alan (2018). Osteogenic sarcoma in an adolescent with cystic fibrosis: successful treatment despite significant obstacles. Frontiers in Pediatrics, 6 245. doi: 10.3389/fped.2018.00245

Osteogenic sarcoma in an adolescent with cystic fibrosis: successful treatment despite significant obstacles

2018

Journal Article

Factors influencing the documentation of fertility-related discussions for adolescents and young adults with cancer

Skaczkowski, G., White, V., Thompson, K., Bibby, H., Coory, M., Pinkerton, R., Nicholls, W., Orme, L. M., Conyers, R., Phillips, M. B., Osborn, M., Harrup, R. and Anazodo, A. (2018). Factors influencing the documentation of fertility-related discussions for adolescents and young adults with cancer. European Journal of Oncology Nursing, 34, 42-48. doi: 10.1016/j.ejon.2018.02.007

Factors influencing the documentation of fertility-related discussions for adolescents and young adults with cancer

2018

Journal Article

Experiences of care of adolescents and young adults with cancer in Australia

White, Victoria, Skaczkowski, Gemma, Thompson, Kate, Bibby, Helen, Coory, Michael, Pinkerton, Ross, Nicholls, Wayne, Orme, Lisa M., Conyers, Rachel, Phillips, Marianne B., Osborn, Michael, Harrup, Rosemary and Anazodo, Antoinette (2018). Experiences of care of adolescents and young adults with cancer in Australia. Journal of Adolescent and Young Adult Oncology, 7 (3), 315-325. doi: 10.1089/jayao.2017.0104

Experiences of care of adolescents and young adults with cancer in Australia

2017

Journal Article

Phase 1/2 KEYNOTE-051 study of pembrolizumab (pembro) in pediatric patients (pts) with advanced melanoma or a PD-L1<sup>+</sup> advanced, relapsed, or refractory solid tumor or lymphoma

Geoerger, Birgit, Kang, Hyoung Jin, Yalon-Oren, Michal, Marshall, Lynley V., Vezina, Catherine, Pappo, Alberto S., Laetsch, Theodore Willis, Petrilli, Antonio Sergio, Handgretinger, Rupert, Toporski, Jacek, Glade-Bender, Julia, Nicholls, Wayne, Fox, Elizabeth, DuBois, Steven G., Macy, Margaret, Cohn, Susan Lerner, Pathiraja, Kumudu, Diede, Scott J., Ebbinghaus, Scot and Pinto, Navin R. (2017). Phase 1/2 KEYNOTE-051 study of pembrolizumab (pembro) in pediatric patients (pts) with advanced melanoma or a PD-L1+ advanced, relapsed, or refractory solid tumor or lymphoma. Journal of Clinical Oncology, 35 (S15), 10525-10525. doi: 10.1200/jco.2017.35.15_suppl.10525

Phase 1/2 KEYNOTE-051 study of pembrolizumab (pembro) in pediatric patients (pts) with advanced melanoma or a PD-L1<sup>+</sup> advanced, relapsed, or refractory solid tumor or lymphoma

2016

Journal Article

Inconsistencies and time delays in site-specific research approvals hinder collaborative clinical research in Australia

White, V. M., Bibby, H., Green, M., Anazodo, A., Nicholls, W., Pinkerton, R., Phillips, M., Harrup, R., Osborn, M., Orme, L. M., Conyers, R., Thompson, K. and Coory, M. (2016). Inconsistencies and time delays in site-specific research approvals hinder collaborative clinical research in Australia. Internal Medicine Journal, 46 (9), 1023-1029. doi: 10.1111/imj.13191

Inconsistencies and time delays in site-specific research approvals hinder collaborative clinical research in Australia