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2013

Journal Article

Transthyretin-thyroid hormone internalization by trophoblasts

Landers, K. A., Li, H., Subramaniam, V. N., Mortimer, R. H. and Richard, K. (2013). Transthyretin-thyroid hormone internalization by trophoblasts. Placenta, 34 (8), 716-718. doi: 10.1016/j.placenta.2013.05.005

Transthyretin-thyroid hormone internalization by trophoblasts

2013

Journal Article

Iron storage disease in Asia-Pacific populations: the importance of non-HFE mutations

McDonald, Cameron J., Wallace, Daniel F., Crawford, Darrell H. G. and Subramaniam, V. Nathan (2013). Iron storage disease in Asia-Pacific populations: the importance of non-HFE mutations. Journal of Gastroenterology and Hepatology, 28 (7), 1087-1094. doi: 10.1111/jgh.12222

Iron storage disease in Asia-Pacific populations: the importance of non-HFE mutations

2013

Conference Publication

PROXIMITY LIGATION ASSAYS INDICATE THAT HEMOCHROMATOSIS PROTEINS HFE AND TRANSFERRIN RECEPTOR 2 (TFR2) DO NOT INTERACT

Rishi, Gautam, Wallace, Daniel and Subramaniam, V. Nathan (2013). PROXIMITY LIGATION ASSAYS INDICATE THAT HEMOCHROMATOSIS PROTEINS HFE AND TRANSFERRIN RECEPTOR 2 (TFR2) DO NOT INTERACT. HOBOKEN: WILEY-BLACKWELL.

PROXIMITY LIGATION ASSAYS INDICATE THAT HEMOCHROMATOSIS PROTEINS HFE AND TRANSFERRIN RECEPTOR 2 (TFR2) DO NOT INTERACT

2013

Conference Publication

IDENTIFICATION OF GENES AND VARIANT ALLELES ASSOCIATED WITH IRON OVERLOAD IN HEMOCHROMATOSIS HFE C282Y HOMOZYGOTES

McLaren, Christine E., Phatak, Pradyumna D., Adams, Paul C., Subramaniam, V. Nathan, Barton, James C., Garner, Chad P., Powell, Lawrie W., Gurrin, Lyle C., Allen, Katrina J., Nickerson, Deborah A., Ramm, Grant A., Anderson, Gregory J. and McLaren, Gordon D. (2013). IDENTIFICATION OF GENES AND VARIANT ALLELES ASSOCIATED WITH IRON OVERLOAD IN HEMOCHROMATOSIS HFE C282Y HOMOZYGOTES. HOBOKEN: WILEY-BLACKWELL.

IDENTIFICATION OF GENES AND VARIANT ALLELES ASSOCIATED WITH IRON OVERLOAD IN HEMOCHROMATOSIS HFE C282Y HOMOZYGOTES

2013

Conference Publication

Differential Response of the Hepcidin Regulatory Pathway to Oral Versus Perenteral Iron in Mice Lacking Hfe and Tfr2

McDonald, Cameron, Wallace, Daniel, Ostini, Lesa and Subramaniam, Nathan (2013). Differential Response of the Hepcidin Regulatory Pathway to Oral Versus Perenteral Iron in Mice Lacking Hfe and Tfr2. HOBOKEN: WILEY-BLACKWELL.

Differential Response of the Hepcidin Regulatory Pathway to Oral Versus Perenteral Iron in Mice Lacking Hfe and Tfr2

2013

Journal Article

A novel mouse model of veno-occlusive disease provides strategies to prevent thioguanine-induced hepatic toxicity

Oancea, Iulia, Png, Chin Wen, Das, Indrajit, Lourie, Rohan, Winkler, Ingrid G., Eri, Rajaraman, Subramaniam, Nathan, Jinnah, H. A., McWhinney, Brett C., Levesque, Jean-Pierre, McGuckin, Michael A., Duley, John A. and Florin, Timothy H. J. (2013). A novel mouse model of veno-occlusive disease provides strategies to prevent thioguanine-induced hepatic toxicity. Gut, 62 (4), 594-605. doi: 10.1136/gutjnl-2012-302274

A novel mouse model of veno-occlusive disease provides strategies to prevent thioguanine-induced hepatic toxicity

2013

Journal Article

Centrobin regulates centrosome function in interphase cells by limiting pericentriolar matrix recruitment

Jeffery, Jessie M., Grigoriev, Ilya, Poser, Ina, van der Horst, Armando, Hamilton, Nicholas, Waterhouse, Nigel, Bleier, Jonathan, Subramaniam, V. Nathan, Maly, Ivan V., Akhmanova, Anna and Khanna, Kum Kum (2013). Centrobin regulates centrosome function in interphase cells by limiting pericentriolar matrix recruitment. Cell Cycle, 12 (6), 899-906. doi: 10.4161/cc.23879

Centrobin regulates centrosome function in interphase cells by limiting pericentriolar matrix recruitment

2013

Conference Publication

An iron-deficient diet attenuates diet-induced hepatic steatosis in HFE-associated non-alcoholic fatty liver disease using Hfe(-/-) mice

Wilkinson, A. S., Bridle, K. R., Britton, L. J., Jaskowski, L. A., Fletcher, L. M., Subramaniam, V. N. and Crawford, D. H. G. (2013). An iron-deficient diet attenuates diet-induced hepatic steatosis in HFE-associated non-alcoholic fatty liver disease using Hfe(-/-) mice. The Australian Gastroenterology Week 2013, Melbourne, VIC Australia, 7 - 9 October 2013. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/jgh.12365

An iron-deficient diet attenuates diet-induced hepatic steatosis in HFE-associated non-alcoholic fatty liver disease using Hfe(-/-) mice

2013

Conference Publication

Heterozygous Hfe (haemochromatosis) gene deletion contributes to hepatic iron loading but not steatosis in mice fed a high fat diet

Britton, L., Jaskowski, L., Wilkinson, A., Bridle, K., Subramaniam, N. and Crawford, D. (2013). Heterozygous Hfe (haemochromatosis) gene deletion contributes to hepatic iron loading but not steatosis in mice fed a high fat diet. The Australian Gastroenterology Week 2013, Melbourne, VIC Australia, 7 - 9 October 2013. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/jgh.12365

Heterozygous Hfe (haemochromatosis) gene deletion contributes to hepatic iron loading but not steatosis in mice fed a high fat diet

2013

Conference Publication

Isolated Hepatic Iron Deficiency Despite Abundant Systemic Iron in Mdr2-/- Mice: Integrity of the Biliary Transport System Is Important in Liver Iron Homeostasis

Sobbe, Amy, Frazer, David, Bridle, Kim, Jaskowski, Lesley, Ostini, Lesa, de Guzman, Erika, Santrampurwala, Nishreen, Anderson, Gregory, Subramaniam, V. Nathan and Crawford, Darrell (2013). Isolated Hepatic Iron Deficiency Despite Abundant Systemic Iron in Mdr2-/- Mice: Integrity of the Biliary Transport System Is Important in Liver Iron Homeostasis. 5th Meeting of the International BioIron Society, University College London UK, 14 - 18 May 2013. Hoboken, NJ United States: John Wiley and Sons, Inc. doi: 10.1002/ajh.23453

Isolated Hepatic Iron Deficiency Despite Abundant Systemic Iron in Mdr2-/- Mice: Integrity of the Biliary Transport System Is Important in Liver Iron Homeostasis

2013

Journal Article

Excess iron modulates endoplasmic reticulum stress-associated pathways in a mouse model of alcohol and high-fat diet-induced liver injury

Tan, Terrence C. H., Crawford, Darrell H. G., Jaskowski, Lesley A., Subramaniam,V. Nathan, Clouston, Andrew D., Crane, Denis I., Bridle, Kim R., Anderson, Gregory J. and Fletcher, Linda M. (2013). Excess iron modulates endoplasmic reticulum stress-associated pathways in a mouse model of alcohol and high-fat diet-induced liver injury. Laboratory Investigation, 93 (12), 1295-1312. doi: 10.1038/labinvest.2013.121

Excess iron modulates endoplasmic reticulum stress-associated pathways in a mouse model of alcohol and high-fat diet-induced liver injury

2013

Conference Publication

Impaired iron uptake in Mdr2(-/-) mice results in hepatic iron deficiency: implications for patients with cholestatic liver injury

Sobbe, A. L., Frazer, D. M., Bridle, K. R., Jaskowski, L. A., Anderson, G. J., Subramaniam, V. N. and Crawford, D. H. (2013). Impaired iron uptake in Mdr2(-/-) mice results in hepatic iron deficiency: implications for patients with cholestatic liver injury. The Australian Gastroenterology Week 2013, Melbourne, VIC Australia, 7 - 9 October 2013. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/jgh.12365

Impaired iron uptake in Mdr2(-/-) mice results in hepatic iron deficiency: implications for patients with cholestatic liver injury

2013

Conference Publication

Heterozygous Deletion of the Hfe Gene Contributes to Hepatic Iron Loading But Not Steatosis in Mice Fed a High Fat Diet

Britton, Laurence, Jaskowski, Lesley, Wilkinson, Ashley, Bridle, Kim, Subramaniam, Nathan and Crawford, Darrell (2013). Heterozygous Deletion of the Hfe Gene Contributes to Hepatic Iron Loading But Not Steatosis in Mice Fed a High Fat Diet. 5th Meeting of the International BioIron Society, University College London UK, 14 - 18 May 2013. Hoboken, NJ United States: John Wiley and Sons, Inc. doi: 10.1002/ajh.23453

Heterozygous Deletion of the Hfe Gene Contributes to Hepatic Iron Loading But Not Steatosis in Mice Fed a High Fat Diet

2013

Conference Publication

Hfe-associated steatohepatitis: Expression profiling and identifying the molecular basis of liver injury

Santrampurwala, N., Bridle, K. R., Heritage, M. L., Jaskowski, L. A., Wilkinson, A. S., Subramaniam, V. N. and Crawford, D. H. G. (2013). Hfe-associated steatohepatitis: Expression profiling and identifying the molecular basis of liver injury. The Australian Gastroenterology Week 2013, Melbourne, VIC Australia, 7 - 9 October 2013. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/jgh.12365

Hfe-associated steatohepatitis: Expression profiling and identifying the molecular basis of liver injury

2013

Conference Publication

Clinically Identified Tmprss6 Mutations Result in Either Trafficking Defects or Inability to Cleave Hemojuvelin

Bennett, Nigel C., McDonald, Cameron J., Wallace, Daniel F., Hooper, John D., Lopez-Otin, Carlos and Subramaniam, V. Nathan (2013). Clinically Identified Tmprss6 Mutations Result in Either Trafficking Defects or Inability to Cleave Hemojuvelin. BioIron 2013: 5th Meeting of the International BioIron Society, University College London UK, April 14 – 18, 2013. Hoboken, United States: Jossey Bass, Ed. & Pub.. doi: 10.1002/ajh.23453

Clinically Identified Tmprss6 Mutations Result in Either Trafficking Defects or Inability to Cleave Hemojuvelin

2013

Conference Publication

New genetic complexity underlying atypical iron disorders

McDonald, C. J., Wallace, D. F., Crawford, D. H. and Subramaniam, V. N. (2013). New genetic complexity underlying atypical iron disorders. Australian Gastroenterology Week 2013, Melbourne, Australia, 7-9 October 2013. Richmond Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/jgh.12365

New genetic complexity underlying atypical iron disorders

2013

Conference Publication

Administration of an iron-deficient diet attenuates diet-induced hepatic steatosis in HFE-associated non-alcoholic fatty liver disease using Hfe-/- mice

Wilkinson, Ashley S., Bridle, Kim, Britton, Laurence, Jaskowski, Lesley, Fletcher, Linda M., Subramaniam, V. Nathan and Crawford, Darrell H. (2013). Administration of an iron-deficient diet attenuates diet-induced hepatic steatosis in HFE-associated non-alcoholic fatty liver disease using Hfe-/- mice. 64th Annual Meeting and Postgraduate Course of the American Association for the Study of Liver Diseases, Washington, DC, United States, 1 - 5 November 2013. Hoboken, NJ, United States: John Wiley & Sons.

Administration of an iron-deficient diet attenuates diet-induced hepatic steatosis in HFE-associated non-alcoholic fatty liver disease using Hfe-/- mice

2012

Journal Article

Hepatic Iron Deposition Does Not Predict Extrahepatic Iron Loading in Mouse Models of Hereditary Hemochromatosis

Subramaniam, V. Nathan, McDonald, Cameron J., Ostini, Lesa, Lusby, Patricia E., Wockner, Leesa F., Ramm, Grant A. and Wallace, Daniel F. (2012). Hepatic Iron Deposition Does Not Predict Extrahepatic Iron Loading in Mouse Models of Hereditary Hemochromatosis. American Journal of Pathology, 181 (4), 1173-1179. doi: 10.1016/j.ajpath.2012.06.025

Hepatic Iron Deposition Does Not Predict Extrahepatic Iron Loading in Mouse Models of Hereditary Hemochromatosis

2012

Conference Publication

The progression of NAFLD to NASH in a mouse model of Hfe(-/-)- associated steatohepatitis is attenuated by co-administration of curcumin and vitamin E

Heritage, Mandy, Jaskowski, Lesley, Wilkinson, Ashley S., Britton, Laurence, Tan, Terrence C., Clouston, Andrew D., Bridle, Kim, Anderson, Gregory J., Macdonald, Graeme A., Fletcher, Linda M., Subramaniam, V. Nathan and Crawford, Darrell H. (2012). The progression of NAFLD to NASH in a mouse model of Hfe(-/-)- associated steatohepatitis is attenuated by co-administration of curcumin and vitamin E. 63rd Annual Meeting of the American Association for the Study of Liver Diseases (AASLD), Boston MA., United States, 9-13 November 2012. Hoboken, NJ United States: John Wiley and Sons. doi: 10.1002/hep.26040

The progression of NAFLD to NASH in a mouse model of Hfe(-/-)- associated steatohepatitis is attenuated by co-administration of curcumin and vitamin E

2012

Conference Publication

The progression of NAFLD to NASH in a mouse model of Hfe(-/-)-associated steatohepatitis is attenuated by co-administration of curcumin and vitamin E

Heritage, Mandy L., Wilkinson, Ashley S., Jaskowski, Lesley A., Britton, Laurence J., Tan, Terrence C., Bridle, Kim, Clouston, Andrew, Anderson, Gregory, Fletcher, Linda M., Macdonald, Graeme A., Subramaniam, Nathan and Crawford, Darrell H. (2012). The progression of NAFLD to NASH in a mouse model of Hfe(-/-)-associated steatohepatitis is attenuated by co-administration of curcumin and vitamin E. Abstracts of the Australian Gastroenterology Week 2012, Adelaide, SA, Australia, 16-19 October 2012. Richmond, VIC, Australia: Wiley-Blackwell. doi: 10.1111/j.1440-1746.2011.07251.x

The progression of NAFLD to NASH in a mouse model of Hfe(-/-)-associated steatohepatitis is attenuated by co-administration of curcumin and vitamin E