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2024 Journal Article Effects of iron overload in human joint tissue explant cultures and animal modelsPrasadam, Indira, Schrobback, Karsten, Kranz-Rudolph, Bastian, Fischer, Nadine, Sonar, Yogita, Sun, Antonia RuJia, Secondes, Eriza, Klein, Travis, Crawford, Ross, Subramaniam, V. Nathan and Rishi, Gautam (2024). Effects of iron overload in human joint tissue explant cultures and animal models. Journal of Molecular Medicine, 103 (1) 102616, 1-14. doi: 10.1007/s00109-024-02495-9 |
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2023 Journal Article Gene variants implicated in steatotic liver disease: opportunities for diagnostics and therapeuticsHuang, Gary, Wallace, Daniel F., Powell, Elizabeth E., Rahman, Tony, Clark, Paul J. and Subramaniam, V. Nathan (2023). Gene variants implicated in steatotic liver disease: opportunities for diagnostics and therapeutics. Biomedicines, 11 (10) 2809, 1-15. doi: 10.3390/biomedicines11102809 |
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2022 Journal Article Engineering peptide inhibitors of the HFE–transferrin receptor 1 complexGoncalves Monteiro, Daniela Goncalves, Rishi, Gautam, Gorman, Declan M., Burnet, Guillaume, Aliyanto, Randy, Rosengren, K. Johan, Frazer, David M., Subramaniam, V. Nathan and Clark, Richard J. (2022). Engineering peptide inhibitors of the HFE–transferrin receptor 1 complex. Molecules, 27 (19) 6581, 1-13. doi: 10.3390/molecules27196581 |
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2021 Journal Article Cancer: The role of iron and ferroptosisRishi, Gautam, Huang, Gary and Subramaniam, V. Nathan (2021). Cancer: The role of iron and ferroptosis. International Journal of Biochemistry and Cell Biology, 141 106094, 106094. doi: 10.1016/j.biocel.2021.106094 |
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2021 Journal Article Genetic diagnosis in hereditary hemochromatosis: discovering and understanding the biological relevance of variantsBaas, Floor S., Rishi, Gautam, Swinkels, Dorine W. and Subramaniam, V. Nathan (2021). Genetic diagnosis in hereditary hemochromatosis: discovering and understanding the biological relevance of variants. Clinical Chemistry, 67 (10), 1324-1341. doi: 10.1093/clinchem/hvab130 |
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2021 Journal Article In vitro identification and characterisation of iron chelating catechol-containing natural products and derivativesHawula, Zachary J., Davis, Rohan A., Wallace, Daniel F., Rishi, Gautam and Subramaniam, V. Nathan (2021). In vitro identification and characterisation of iron chelating catechol-containing natural products and derivatives. BioMetals, 34 (4), 855-866. doi: 10.1007/s10534-021-00312-1 |
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2021 Journal Article Iron depletion attenuates steatosis in a mouse model of non-alcoholic fatty liver disease: Role of iron-dependent pathwaysCrawford, Darrell H.G., Ross, Diana G.F., Jaskowski, Lesley-Anne, Burke, Leslie J., Britton, Laurence J., Musgrave, Nick, Briskey, David, Rishi, Gautam, Bridle, Kim R. and Subramaniam, V. Nathan (2021). Iron depletion attenuates steatosis in a mouse model of non-alcoholic fatty liver disease: Role of iron-dependent pathways. Biochimica et Biophysica Acta - Molecular Basis of Disease, 1867 (7) 166142, 166142. doi: 10.1016/j.bbadis.2021.166142 |
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2021 Journal Article The effect of the flavonol rutin on serum and liver iron content in a genetic mouse model of iron overloadHawula, Zachary J., Secondes, Eriza S., Wallace, Daniel F., Rishi, Gautam and Subramaniam, V. Nathan (2021). The effect of the flavonol rutin on serum and liver iron content in a genetic mouse model of iron overload. Bioscience Reports, 41 (7) BSR20210720. doi: 10.1042/BSR20210720 |
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2021 Journal Article Gender biased neuroprotective effect of Transferrin Receptor 2 deletion in multiple models of Parkinson’s diseaseMilanese, Chiara, Gabriels, Sylvia, Barnhoorn, Sander, Cerri, Silvia, Ulusoy, Ayse, Gornati, S. V., Wallace, Daniel F., Blandini, Fabio, Di Monte, Donato A., Subramaniam, V. Nathan and Mastroberardino, Pier G. (2021). Gender biased neuroprotective effect of Transferrin Receptor 2 deletion in multiple models of Parkinson’s disease. Cell Death and Differentiation, 28 (5), 1720-1732. doi: 10.1038/s41418-020-00698-4 |
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2020 Journal Article Increased frequency of GNPAT p.D519G in compound HFE p.C282Y/p.H63D heterozygotes with elevated serum ferritin levelsSecondes, Eriza S., Wallace, Daniel F., Rishi, Gautam, McLaren, Gordon D., McLaren, Christine E., Chen, Wen-Pin, Ramm, Louise E., Powell, Lawrie W., Ramm, Grant A., Barton, James C. and Subramaniam, V. Nathan (2020). Increased frequency of GNPAT p.D519G in compound HFE p.C282Y/p.H63D heterozygotes with elevated serum ferritin levels. Blood Cells, Molecules, and Diseases, 85 102463, 1-5. doi: 10.1016/j.bcmd.2020.102463 |
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2020 Journal Article Hepatocyte-specific deletion of peroxisomal protein PEX13 results in disrupted iron homeostasisRishi, Gautam, Bhatia, Maneet, Secondes, Eriza S., Melino, Michelle, Crane, Denis and Subramaniam, V. Nathan (2020). Hepatocyte-specific deletion of peroxisomal protein PEX13 results in disrupted iron homeostasis. Biochimica Et Biophysica Acta-Molecular Basis of Disease, 1866 (10) 165882. doi: 10.1016/j.bbadis.2020.165882 |
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2020 Journal Article Dysregulated hepcidin response to dietary iron in male mice with reduced Gnpat expressionRishi, Gautam, Secondes, Eriza S., Asplett, Kiran, Wallace, Daniel F., Ostini, Lesa, Berger, Johannes and Subramaniam, V. Nathan (2020). Dysregulated hepcidin response to dietary iron in male mice with reduced Gnpat expression. Bioscience Reports, 40 (8) BSR20201508. doi: 10.1042/bsr20201508 |
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2020 Journal Article Evidence for dimerization of ferroportin in a human hepatic cell line using proximity ligation assaysRishi, Gautam, Secondes, Eriza S., Wallace, Daniel F. and Subramaniam, V. Nathan (2020). Evidence for dimerization of ferroportin in a human hepatic cell line using proximity ligation assays. Bioscience Reports, 40 (5) BSR20191499. doi: 10.1042/bsr20191499 |
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2019 Journal Article Correction to: The potential prognostic utility of salivary galectin-3 concentrations in heart failure (Clinical Research in Cardiology, (2019), 10.1007/s00392-019-01557-0)Zhang, Xi, Karunathilaka, Nuwan, Senanayake, Sameera, Subramaniam, V. Nathan, Chan, Wandy, Kostner, Karam, Fraser, John, Atherton, John J. and Punyadeera, Chamindie (2019). Correction to: The potential prognostic utility of salivary galectin-3 concentrations in heart failure (Clinical Research in Cardiology, (2019), 10.1007/s00392-019-01557-0). Clinical Research in Cardiology, 109 (6), 693-693. doi: 10.1007/s00392-019-01583-y |
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2019 Journal Article Therapeutic advances in regulating the hepcidin/ferroportin axisHawula, Zachary J., Wallace, Daniel F., Subramaniam, V. Nathan and Rishi, Gautam (2019). Therapeutic advances in regulating the hepcidin/ferroportin axis. Pharmaceuticals, 12 (4) 170, 170. doi: 10.3390/ph12040170 |
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2019 Journal Article The potential prognostic utility of salivary galectin-3 concentrations in heart failureZhang, Xi, Karunathilaka, Nuwan, Senanayake, Sameera, Subramaniam, V. Nathan, Chan, Wandy, Kostner, Karam, Fraser, John, Atherton, John J. and Punyadeera, Chamindie (2019). The potential prognostic utility of salivary galectin-3 concentrations in heart failure. Clinical Research in Cardiology, 109 (6), 685-692. doi: 10.1007/s00392-019-01557-0 |
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2018 Journal Article Cirrhosis in hemochromatosis: independent risk factors in 368 HFE p.C282Y homozygotesBarton, James C., McLaren, Christine E., Chen, Wen-Pin, Ramm, Grant A., Anderson, Gregory J., Powell, Lawrie W., Subramaniam, V. Nathan, Adams, Paul C., Phatak, Pradyumna D., Gurrin, Lyle C., Phillips, John D., Parker, Charles J., Emond, Mary J. and McLaren, Gordon D. (2018). Cirrhosis in hemochromatosis: independent risk factors in 368 HFE p.C282Y homozygotes. Annals of Hepatology, 17 (5), 871-879. doi: 10.5604/01.3001.0012.3169 |
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2018 Journal Article Hemochromatosis: Evaluation of the dietary iron model and regulation of hepcidinRishi, Gautam, Secondes, Eriza S. and Subramaniam, V. Nathan (2018). Hemochromatosis: Evaluation of the dietary iron model and regulation of hepcidin. Biochimica et Biophysica Acta - Molecular Basis of Disease, 1864 (8), 2550-2556. doi: 10.1016/j.bbadis.2018.05.005 |
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2018 Journal Article Phenotypic analysis of hemochromatosis subtypes reveals variations in severity of iron overload and clinical diseaseSandhu, Kam, Flintoff, Kaledas, Chatfield, Mark D., Dixon, Jeannette L., Ramm, Louise E., Ramm, Grant A., Powell, Lawrie W., Subramaniam, V. Nathan and Wallace, Daniel F. (2018). Phenotypic analysis of hemochromatosis subtypes reveals variations in severity of iron overload and clinical disease. Blood, 132 (1), 101-110. doi: 10.1182/blood-2018-02-830562 |
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2018 Journal Article Hepatic iron concentration correlates with insulin sensitivity in nonalcoholic fatty liver diseaseBritton, Laurence, Bridle, Kim, Reiling, Janske, Santrampurwala, Nishreen, Wockner, Leesa, Ching, Helena, Stuart, Katherine, Subramaniam, V Nathan, Jeffrey, Gary, St Pierre, Tim, House, Michael, Gummer, Joel, Trengove, Robert, Olynyk, John, Crawford, Darrell and Adams, Leon (2018). Hepatic iron concentration correlates with insulin sensitivity in nonalcoholic fatty liver disease. Hepatology Communications, 2 (6), 644-653. doi: 10.1002/hep4.1190 |
