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2009 Journal Article Thiosemicarbazones from the old to new: Iron chelators that are more than just ribonucleotide reductase inhibitorsYu, Yu, Kalinowski, Danuta S., Kovacevic, Zaklina, Siafakas, Aritee R., Jansson, Patric J., Stefani, Christian, Lovejoy, David B., Sharpe, Philip C., Bernhardt, Paul V. and Richardson, Des R. (2009). Thiosemicarbazones from the old to new: Iron chelators that are more than just ribonucleotide reductase inhibitors. Journal of Medicinal Chemistry, 52 (17), 5271-5294. doi: 10.1021/jm900552r |
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2009 Journal Article 2-acetylpyridine thiosemicarbazones are potent iron chelators and antiproliferative agents: Redox activity, iron complexation and characterization of their antitumor activityRichardson, Des R., Kalinowski, Danuta S., Richardson, Vera, Sharpe, Philip C., Lovejoy, David B., Islam, Mohammad and Bernhardt, Paul V. (2009). 2-acetylpyridine thiosemicarbazones are potent iron chelators and antiproliferative agents: Redox activity, iron complexation and characterization of their antitumor activity. Journal of Medicinal Chemistry, 52 (5), 1459-1470. doi: 10.1021/jm801585u |
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2009 Journal Article Iron chelators of the dipyridylketone thiosemicarbazone class: Precomplexation and transmetalation effects on anticancer activityBernhardt, Paul V., Sharpe, Philip C., Islam, Mohammed, Lovejoy, David B., Kalinowski, Danuta S. and Richardson, Des R. (2009). Iron chelators of the dipyridylketone thiosemicarbazone class: Precomplexation and transmetalation effects on anticancer activity. Journal of Medicinal Chemistry, 52 (2), 407-415. doi: 10.1021/jm801012z |
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2008 Journal Article Structure-activity relationships of novel iron chelators for the treatment of iron overload disease: The methyl pyrazinylketone isonicotinoyl hydrazone seriesKalinowski, Danuta S., Sharpe, Philip C., Bernhardt, Paul V. and Richardson, Des R. (2008). Structure-activity relationships of novel iron chelators for the treatment of iron overload disease: The methyl pyrazinylketone isonicotinoyl hydrazone series. Journal of Medicinal Chemistry, 51 (2), 331-344. doi: 10.1021/jm7012562 |
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2008 Journal Article Tuning the antiproliferative activity of biologically active iron chelators: characterization of the coordination chemistry and biological efficacy of 2-acetylpyridine and 2-benzoylpyridine hydrazone ligandsBernhardt, P.V., Wilson, G.J., Sharpe, P.C., Kalinowski, D.S. and Richardson, D.R. (2008). Tuning the antiproliferative activity of biologically active iron chelators: characterization of the coordination chemistry and biological efficacy of 2-acetylpyridine and 2-benzoylpyridine hydrazone ligands. Journal of Biological Inorganic Chemistry, 13 (1), 107-119. doi: 10.1007/s00775-007-0300-4 |
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2008 Conference Publication Chelators as Medicinal Agents: Iron and BeyondSharpe, Philip (2008). Chelators as Medicinal Agents: Iron and Beyond. Inorganic Chemistry Conference IC08, Christchurch, New Zealand, 14-18 December 2008. |
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2007 Journal Article Design, synthesis, and characterization of new iron chelators with anti-proliferative activity: Structure-activity relationships of novel thiohydrazone analoguesKalinowski, DS, Sharpe, PC, Bernhardt, PV and Richardson, DR (2007). Design, synthesis, and characterization of new iron chelators with anti-proliferative activity: Structure-activity relationships of novel thiohydrazone analogues. Journal of Medicinal Chemistry, 50 (24), 6212-6225. doi: 10.1021/jm070839q |
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2007 Journal Article Design, synthesis, and characterization of novel iron chelators: Structure-activity relationships of the 2-benzoylpyridine thiosemicarbazone series and their 3-nitrobenzoyl analogues as potent antitumor agentsKalinowski, D. S., Yu, Y., Sharpe, P. C., Islam, M., Liao, Y. T., Lovejoy, D. B., Kumar, N., Bernhardt, P. V. and Richardson, D. R. (2007). Design, synthesis, and characterization of novel iron chelators: Structure-activity relationships of the 2-benzoylpyridine thiosemicarbazone series and their 3-nitrobenzoyl analogues as potent antitumor agents. Journal of Medicinal Chemistry, 50 (15), 3716-3729. doi: 10.1021/jm070445z |
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2007 Journal Article Hydrazone chelators for the treatment of iron overload disorders: iron coordination chemistry and biological activityBernhardt, Paul V., Chin, Piao, Sharpe, Philip C. and Richardson, Des R. (2007). Hydrazone chelators for the treatment of iron overload disorders: iron coordination chemistry and biological activity. Dalton Transactions, 2007 (30), 3232-3244. doi: 10.1039/b704102k |
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2007 Book Chapter Amyloid peptides and proteins in reviewHarrison, R. S., Sharpe, P. C., Singh, Y. and Fairlie, D. P. (2007). Amyloid peptides and proteins in review. Reviews of physiology, biochemistry and pharmacology. (pp. 1-77) edited by S. G. Amara, B. Bamberg, T. Fleischmann, S. C. Gudermann, S. C. Hebert, R. Jahn, W. J. Lederer, R. Lill, A. Miyajima, S. Offermanns and R. Zechner. Berlin, Germany: Springer. doi: 10.1007/112_2007_0701 |
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2006 Journal Article Dipyridyl thiosemicarbazone chelators with potent and selective antitumor activity form iron complexes with redox activityRichardson, D. R., Sharpe, P. C., Lovejoy, D. B., Senaratne, D., Kalinowski, D. S., Islam, M. and Bernhardt, P. V. (2006). Dipyridyl thiosemicarbazone chelators with potent and selective antitumor activity form iron complexes with redox activity. Journal of Medicinal Chemistry, 49 (22), 6510-6521. doi: 10.1021/jm0606342 |
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2006 Conference Publication Peptide bundles: Loops, helices, strands and sheetsFairlie, D., Singh, Y. and Sharpe, P. C. (2006). Peptide bundles: Loops, helices, strands and sheets. The American Chemical Society Meeting 2006, Atlanta, GA, USA, 26 -30 March, 2006. Washington: American Chemical Society. |
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2006 Journal Article Transition metal complexes as mediator-titrants in protein redox potentiometryBernhardt, P. V., Chen, K. I. and Sharpe, P. C. (2006). Transition metal complexes as mediator-titrants in protein redox potentiometry. Journal of Biological Inorganic Chemistry, 11 (7), 930-936. doi: 10.1007/s00775-006-0148-z |
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2005 Journal Article Novel diaroylhydrazine ligands as iron chelators: coordination chemistry and biological activityBernhardt, Paul V., Chin, Piao, Sharpe, Philip C., Wang, Jing-Yan C. and Richardson, Des R. (2005). Novel diaroylhydrazine ligands as iron chelators: coordination chemistry and biological activity. Journal of Biological Inorganic Chemistry, 10 (7), 761-777. doi: 10.1007/s00775-005-0018-0 |
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2003 Conference Publication Template-assembled peptide loops, helices, sheets and nanofibresFairlie, DP, Singh, Y, Sharpe, P and Stoermer, M (2003). Template-assembled peptide loops, helices, sheets and nanofibres. 225th National Meeting of the American-Chemical-Society, New Orleans Louisiana, Mar 23-27, 2003. WASHINGTON: AMER CHEMICAL SOC. |
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2003 Conference Publication Template-assembled peptide loops, helices, sheets, and nanofibersFairlie, David P ., Singh, Yogendra, Sharpe, Philip and Stoermer, Martin (2003). Template-assembled peptide loops, helices, sheets, and nanofibers. 225th ACS National Meeting, New Orleans, LA, United States, 23-27 March 2003. |
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2002 Journal Article Copper(II) nitrite complexes of tripodal ligands derived from 1,1,1-tris(2-pyridyl)methylamineArnold, Phillip J., Davies, Sian C., Durrant, Marcus C., Griffiths, D. Vaughan, Hughes, David L. and Sharpe, Phillip C. (2002). Copper(II) nitrite complexes of tripodal ligands derived from 1,1,1-tris(2-pyridyl)methylamine. Inorganica Chimica Acta, 348 (5), 143-149. doi: 10.1016/S0020-1693(02)01487-1 |
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2001 Journal Article Copper complexes of the functionalised tripodal ligand tris(2-pyridyl)methylamine and its derivativesArnold, PJ, Davies, SC, Dilworth, , Durrant, MC, Griffiths, DV, Hughes, DL, Richards, RL and Sharpe, PC (2001). Copper complexes of the functionalised tripodal ligand tris(2-pyridyl)methylamine and its derivatives. Journal of the Chemical Society-Dalton Transactions (5), 736-746. doi: 10.1039/b008476j |
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2000 Journal Article Structurally reinforced tetraazamacrocyclic complexesBernhardt, PV and Sharpe, PC (2000). Structurally reinforced tetraazamacrocyclic complexes. Inorganic Chemistry, 39 (10), 2020-2025. doi: 10.1021/ic9906353 |
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2000 Journal Article C-substituted macrocycles as candidates for radioimmunotherapyBernhardt, PV and Sharpe, PC (2000). C-substituted macrocycles as candidates for radioimmunotherapy. Inorganic Chemistry, 39 (18), 4123-4129. doi: 10.1021/ic000315f |
