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2016 Journal Article Effects of hormonal contraception on systemic metabolism: cross-sectional and longitudinal evidenceWang, Qin, Wurtz, Peter, Auro, Kirsi, Morin-Papunen, Laure, Kangas, Antti J., Soininen, Pasi, Tiainen, Mika, Tynkkynen, Tuulia, Joensuu, Anni, Havulinna, Aki S., Aalto, Kristiina, Salmi, Marko, Blankenberg, Stefan, Zeller, Tanja, Viikari, Jorma, Kahonen, Mika, Lehtimaki, Terho, Salomaa, Veikko, Jalkanen, Sirpa, Jarvelin, Marjo-Riitta, Perola, Markus, Raitakari, Olli T., Lawlor, Debbie A., Kettunen, Johannes and Ala-Korpela, Mika (2016). Effects of hormonal contraception on systemic metabolism: cross-sectional and longitudinal evidence. International Journal of Epidemiology, 45 (5), 1445-1457. doi: 10.1093/ije/dyw147 |
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2016 Journal Article Metabolic signatures of birthweight in 18 288 adolescents and adultsWurtz, Peter, Wang, Qin, Niironen, Marjo, Tynkkynen, Tuulia, Tiainen, Mika, Drenos, Fotios, Kangas, Antti J., Soininen, Pasi, Skilton, Michael R., Heikkila, Kauko, Pouta, Anneli, Kahonen, Mika, Lehtimaki, Terho, Rose, Richard J., Kajantie, Eero, Perola, Markus, Kaprio, Jaakko, Eriksson, Johan G., Raitakari, Olli T., Lawlor, Debbie A., Smith, George Davey, Jarvelin, Marjo-Riitta, Ala-Korpela, Mika and Auro, Kirsi (2016). Metabolic signatures of birthweight in 18 288 adolescents and adults. International Journal of Epidemiology, 45 (5), 1539-1550. doi: 10.1093/ije/dyw255 |
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2016 Journal Article Metabolic profiling of alcohol consumption in 9778 young adultsWurtz, Peter, Cook, Sarah, Wang, Qin, Tiainen, Mika, Tynkkynen, Tuulia, Kangas, Antti J., Soininen, Pasi, Laitinen, Jaana, Viikari, Jorma, Kahonen, Mika, Lehtimaki, Terho, Perola, Markus, Blankenberg, Stefan, Zeller, Tanja, Mannisto, Satu, Salomaa, Veikko, Jarvelin, Marjo-Riitta, Raitakari, Olli T., Ala-Korpela, Mika and Leon, David A. (2016). Metabolic profiling of alcohol consumption in 9778 young adults. International Journal of Epidemiology, 45 (5), 1493-1506. doi: 10.1093/ije/dyw175 |
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2016 Journal Article Whole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative <i>GFI1B</i> Splice Variants in Human HematopoiesisPolfus, Linda M., Khajuria, Rajiv K., Schick, Ursula M., Pankratz, Nathan, Pazoki, Raha, Brody, Jennifer A., Chen, Ming-Huei, Auer, Paul L., Floyd, James S., Huang, Jie, Lange, Leslie, van Rooij, Frank J. A., Gibbs, Richard A., Metcalf, Ginger, Muzny, Donna, Veeraraghavan, Narayanan, Walter, Klaudia, Chen, Lu, Yanek, Lisa, Becker, Lewis C., Peloso, Gina M., Wakabayashi, Aoi, Kals, Mart, Metspalu, Andres, Esko, Tonu, Fox, Keolu, Wallace, Robert, Franceschini, Nora, Matijevic, Nena ... Sankaran, Vijay G. (2016). Whole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative GFI1B Splice Variants in Human Hematopoiesis. American Journal of Human Genetics, 99 (2), 481-488. doi: 10.1016/j.ajhg.2016.06.016 |
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2016 Journal Article Predicting gene targets from integrative analyses of summary data from GWAS and eQTL studies for 28 human complex traitsPavlides, Jennifer M. Whitehead, Zhu, Zhihong, Gratten, Jacob, Mcrae, Allan F., Wray, Naomi R. and Yang, Jian (2016). Predicting gene targets from integrative analyses of summary data from GWAS and eQTL studies for 28 human complex traits. Genome Medicine, 8 (1) 84, 84. doi: 10.1186/s13073-016-0338-4 |
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2016 Journal Article Genetic pleiotropy in complex traits and diseases: implications for genomic medicineGratten, Jacob and Visscher, Peter M. (2016). Genetic pleiotropy in complex traits and diseases: implications for genomic medicine. Genome Medicine, 8 (78) 78, 1-3. doi: 10.1186/s13073-016-0332-x |
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2016 Journal Article Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in <i>ANGPTL4</i> determining fasting TG levelsvan Leeuwen, Elisabeth M., Sabo, Aniko, Bis, Joshua C., Huffman, Jennifer E., Manichaikul, Ani, Smith, Albert V., Feitosa, Mary F., Demissie, Serkalem, Joshi, Peter K., Duan, Qing, Marten, Jonathan, van Klinken, Jan B., Surakka, Ida, Nolte, Ilja M., Zhang, Weihua, Mbarek, Hamdi, Li-Gao, Ruifang, Trompet, Stella, Verweij, Niek, Evangelou, Evangelos, Lyytikainen, Leo-Pekka, Tayo, Bamidele O., Deelen, Joris, van der Most, Peter J., van der Laan, Sander W., Arking, Dan E., Morrison, Alanna, Dehghan, Abbas, Franco, Oscar H. ... van Duijn, Cornelia M. (2016). Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels. Journal of Medical Genetics, 53 (7), 441-449. doi: 10.1136/jmedgenet-2015-103439 |
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2016 Journal Article Childhood Infections, Socioeconomic Status, and Adult Cardiometabolic RiskLiu, Richard S., Burgner, David P., Sabin, Matthew A., Magnussen, Costan G., Cheung, Michael, Hutri-Kahonen, Nina, Kahonen, Mika, Lehtimaki, Terho, Jokinen, Eero, Laitinen, Tomi, Taittonen, Leena, Dwyer, Terence, Viikari, Jorma S. A., Kivimaki, Mika, Raitakari, Olli T. and Juonala, Markus (2016). Childhood Infections, Socioeconomic Status, and Adult Cardiometabolic Risk. Pediatrics, 137 (6) e20160236. doi: 10.1542/peds.2016-0236 |
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2016 Journal Article Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analysesOkbay, Aysu, Baselmans, Bart M. L., De Neve, Jan-Emmanuel, Turley, Patrick, Nivard, Michel G., Fontana, Mark Alan, Meddens, S. Fleur W., Linner, Richard Karlsson, Rietveld, Cornelius A., Derringer, Jaime, Gratten, Jacob, Lee, James J., Liu, Jimmy Z., de Vlaming, Ronald, Ahluwalia, Tarunveer S., Buchwald, Jadwiga, Cavadino, Alana, Frazier-Wood, Alexis C., Furlotte, Nicholas A., Garfield, Victoria, Geisel, Marie Henrike, Gonzalez, Juan R., Haitjema, Saskia, Karlsson, Robert, van der Laan, Sander W., Ladwig, Karl-Heinz, Lahti, Jari, van der Lee, Sven J., Lind, Penelope A. ... Cesarini, David (2016). Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses. Nature Genetics, 48 (6), 624-633. doi: 10.1038/ng.3552 |
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2016 Journal Article International genome-wide association study consortium identifies novel loci associated with blood pressure in children and adolescentsParmar, Priyakumari Ganesh, Taal, H. Rob, Timpson, Nicholas J., Thiering, Elisabeth, Lehtimaki, Terho, Marinelli, Marcella, Lind, Penelope A., Howe, Laura D., Verwoert, Germaine, Aalto, Ville, Uitterlinden, Andre G., Briollais, Laurent, Evans, Dave M., Wright, Margie J., Newnham, John P., Whitfield, John B., Lyytikainen, Leo-Pekka, Rivadeneira, Fernando, Boomsma, Dorrett I., Viikari, Jorma, Gillman, Matthew W., St Pourcain, Beate, Hottenga, Jouke-Jan, Montgomery, Grant W., Hofman, Albert, Kahonen, Mika, Martin, Nicholas G., Tobin, Martin D., Raitakari, Ollie ... Palmer, Lyle J. (2016). International genome-wide association study consortium identifies novel loci associated with blood pressure in children and adolescents. Circulation: Cardiovascular Genetics, 9 (3), 266-278. doi: 10.1161/CIRCGENETICS.115.001190 |
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2016 Journal Article Genome-wide association study identifies 74 loci associated with educational attainmentOkbay, Aysu, Beauchamp, Jonathan P., Fontana, Mark Alan, Lee, James J., Pers, Tune H., Rietveld, Cornelius A., Turley, Patrick, Chen, Guo-Bo, Emilsson, Valur, Meddens, S. Fleur W., Oskarsson, Sven, Pickrell, Joseph K., Thom, Kevin, Timshel, Pascal, de Vlaming, Ronald, Abdellaoui, Abdel, Ahluwalia, Tarunveer S., Bacelis, Jonas, Baumbach, Clemens, Bjornsdottir, Gyda, Brandsma, Johannes H., Concas, Maria Pina, Derringer, Jaime, Furlotte, Nicholas A., Galesloot, Tessel E., Girotto, Giorgia, Gupta, Richa, Hall, Leanne M., Harris, Sarah E. ... Benjamin, Daniel J. (2016). Genome-wide association study identifies 74 loci associated with educational attainment. Nature, 533 (7604), 539-542. doi: 10.1038/nature17671 |
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2016 Journal Article Evidence for genetic overlap between schizophrenia and age at first birth in womenMehta, Divya, Tropf, Felix C., Gratten, Jacob, Bakshi, Andrew, Zhu, Zhihong, Bacanu, Silviu-Alin, Hemani, Gibran, Magnusson, Patrik K. E., Barban, Nicola, Esko, Tonu, Metspalu, Andres, Snieder, Harold, Mowry, Bryan J., Kendler, Kenneth S., Yang, Jian, Visscher, Peter M., McGrath, John J., Mills, Melinda C., Wray, Naomi R. and Lee, S. Hong (2016). Evidence for genetic overlap between schizophrenia and age at first birth in women. Jama Psychiatry, 73 (5), 497-505. doi: 10.1001/jamapsychiatry.2016.0129 |
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2016 Journal Article Small non-coding RNA expression from anterior cingulate cortex in schizophrenia shows sex specific regulationRagan, Chikako, Patel, Kalpana, Edson, Janette, Zhang, Zong-Hong, Gratten, Jacob and Mowry, Bryan (2016). Small non-coding RNA expression from anterior cingulate cortex in schizophrenia shows sex specific regulation. Schizophrenia Research, 183, 82-87. doi: 10.1016/j.schres.2016.11.024 |
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2016 Journal Article Childhood Psychosocial Factors and Coronary Artery Calcification in Adulthood The Cardiovascular Risk in Young Finns StudyJuonala, Markus, Pulkki-Raback, Laura, Elovainio, Marko, Hakulinen, Christian, Magnussen, Costan G., Sabin, Matthew A., Burgner, David P., Hare, David L., Hartiala, Olli, Ukkonen, Heikki, Saraste, Antti, Kajander, Sami, Hutri-Kahonen, Nina, Kahonen, Mika, Rinta-Kiikka, Irina, Laitinen, Tomi, Kainulainen, Sakari, Viikari, Jorma S. A. and Raitakari, Olli T. (2016). Childhood Psychosocial Factors and Coronary Artery Calcification in Adulthood The Cardiovascular Risk in Young Finns Study. Jama Pediatrics, 170 (5), 466-472. doi: 10.1001/jamapediatrics.2015.4121 |
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2016 Journal Article Prolonged sleep restriction induces changes in pathways involved in cholesterol metabolism and inflammatory responsesAho, Vilma, Ollila, Hanna M., Kronholm, Erkki, Bondia-Pons, Isabel, Soininen, Pasi, Kangas, Antti J., Hilvo, Mika, Seppala, Ilkka, Kettunen, Johannes, Oikonen, Mervi, Raitoharju, Emma, Hyotylainen, Tuulia, Kahonen, Mika, Viikari, Jorma S. A., Harma, Mikko, Sallinen, Mikael, Olkkonen, Vesa M., Alenius, Harri, Jauhiainen, Matti, Paunio, Tiina, Lehtimaki, Terho, Salomaa, Veikko, Oresic, Matej, Raitakari, Olli T., Ala-Korpela, Mika and Porkka-Heiskanen, Tarja (2016). Prolonged sleep restriction induces changes in pathways involved in cholesterol metabolism and inflammatory responses. Scientific Reports, 6 (1) 24828. doi: 10.1038/srep24828 |
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2016 Journal Article Longitudinal study of circulating oxidized LDL and HDL and fatty liver: the Cardiovascular Risk in Young Finns StudyKaikkonen, Jari E., Kresanov, Petri, Ahotupa, Markku, Jula, Antti, Mikkila, Vera, Viikari, Jorma S. A., Juonala, Markus, Hutri-Kahonen, Nina, Kahonen, Mika, Lehtimaki, Terho, Kangas, Antti J., Soininen, Pasi, Ala-Korpela, Mika and Raitakari, Olli T. (2016). Longitudinal study of circulating oxidized LDL and HDL and fatty liver: the Cardiovascular Risk in Young Finns Study. Free Radical Research, 50 (4), 396-404. doi: 10.3109/10715762.2015.1133906 |
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2016 Journal Article Continuous and Dichotomous Metabolic Syndrome Definitions in Youth Predict Adult Type 2 Diabetes and Carotid Artery Intima Media Thickness: The Cardiovascular Risk in Young Finns StudyMagnussen, Costan G., Cheriyan, Sanith, Sabin, Matthew A., Juonala, Markus, Koskinen, Juha, Thomson, Russell, Skilton, Michael R., Kahonen, Mika, Laitinen, Tomi, Taittonen, Leena, Hutri-Kahonen, Nina, Viikari, Jorma S. A. and Raitakari, Olli T. (2016). Continuous and Dichotomous Metabolic Syndrome Definitions in Youth Predict Adult Type 2 Diabetes and Carotid Artery Intima Media Thickness: The Cardiovascular Risk in Young Finns Study. Journal of Pediatrics, 171, 97-+. doi: 10.1016/j.jpeds.2015.10.093 |
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2016 Journal Article Associations of functional alanine-glyoxylate aminotransferase 2 gene variants with atrial fibrillation and ischemic strokeSeppala, Ilkka, Kleber, Marcus E., Bevan, Steve, Lyytikainen, Leo-Pekka, Oksala, Niku, Hernesniemi, Jussi A., Makela, Kari-Matti, Rothwell, Peter M., Sudlow, Cathie, Dichgans, Martin, Mononen, Nina, Vlachopoulou, Efthymia, Sinisalo, Juha, Delgado, Graciela E., Laaksonen, Reijo, Koskinen, Tuomas, Scharnagl, Hubert, Kahonen, Mika, Markus, Hugh S., Marz, Winfried and Lehtimaki, Terho (2016). Associations of functional alanine-glyoxylate aminotransferase 2 gene variants with atrial fibrillation and ischemic stroke. Scientific Reports, 6 23207. doi: 10.1038/srep23207 |
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2016 Journal Article Metabolomic Profiling of Statin Use and Genetic Inhibition of HMG-CoA ReductaseWurtz, Peter, Wang, Qin, Soininen, Pasi, Kangas, Antti J., Fatemifar, Ghazaleh, Tynkkynen, Tuulia, Tiainen, Mika, Perola, Markus, Tillin, Therese, Hughes, Alun D., Mantyselka, Pekka, Kahonen, Mika, Lehtimaki, Terho, Sattar, Naveed, Hingorani, Aroon D., Casas, Juan-Pablo, Salomaa, Veikko, Kivimaki, Mika, Jarvelin, Marjo-Riitta, Smith, George Davey, Vanhala, Mauno, Lawlor, Debbie A., Raitakari, Olli T., Chaturvedi, Nish, Kettunen, Johannes and Ala-Korpela, Mika (2016). Metabolomic Profiling of Statin Use and Genetic Inhibition of HMG-CoA Reductase. Journal of the American College of Cardiology, 67 (10), 1200-1210. doi: 10.1016/j.jacc.2015.12.060 |
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2016 Journal Article Mapping and differential expression analysis from short-read RNA-Seq data in model organismsZhao, Qiong-Yi, Gratten, Jacob, Restaudi, Restuadi and Li, Xuan (2016). Mapping and differential expression analysis from short-read RNA-Seq data in model organisms. Quantitative Biology, 4 (1), 22-35. doi: 10.1007/s40484-016-0060-7 |
