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2016 Journal Article New loci for body fat percentage reveal link between adiposity and cardiometabolic disease riskLu, Yingchang, Day, Felix R., Gustafsson, Stefan, Buchkovich, Martin L., Na, Jianbo, Bataille, Veronique, Cousminer, Diana L., Dastani, Zari, Drong, Alexander W., Esko, Tonu, Evans, David M., Falchi, Mario, Feitosa, Mary F., Ferreira, Teresa, Hedman, Asa K., Haring, Robin, Hysi, Pirro G., Iles, Mark M., Justice, Anne E., Kanoni, Stavroula, Lagou, Vasiliki, Li, Rui, Li, Xin, Locke, Adam, Lu, Chen, Magi, Reedik, Perry, John R. B., Pers, Tune H., Qi, Qibin ... Loos, Ruth J. F. (2016). New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk. Nature Communications, 7 (1) 10495, 10495-10495. doi: 10.1038/ncomms10495 |
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2016 Journal Article Genome-Wide Meta-Analysis of Cotinine Levels in Cigarette Smokers Identifies Locus at 4q13.2Ware, Jennifer J., Chen, Xiangning, Vink, Jacqueline, Loukola, Anu, Minica, Camelia, Pool, Rene, Milaneschi, Yuri, Mangino, Massimo, Menni, Cristina, Chen, Jingchun, Peterson, Roseann E., Auro, Kirsi, Lyytikainen, Leo-Pekka, Wedenoja, Juho, Stiby, Alexander I., Hemani, Gibran, Willemsen, Gonneke, Hottenga, Jouke Jan, Korhonen, Tellervo, Heliovaara, Markku, Perola, Markus, Rose, Richard J., Paternoster, Lavinia, Timpson, Nic, Wassenaar, Catherine A., Zhu, Andy Z. X., Smith, George Davey, Raitakari, Olli T., Lehtimaki, Terho ... Munafo, Marcus R. (2016). Genome-Wide Meta-Analysis of Cotinine Levels in Cigarette Smokers Identifies Locus at 4q13.2. Scientific Reports, 6 20092. doi: 10.1038/srep20092 |
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2016 Journal Article Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levelsKilpelainen, Tuomas O., Carli, Jayne F. Martin, Skowronski, Alicja A., Sun, Qi, Kriebel, Jennifer, Feitosa, Mary F., Hedman, Asa K., Drong, Alexander W., Hayes, James E., Zhao, Jinghua, Pers, Tune H., Schick, Ursula, Grarup, Niels, Kutalik, Zoltan, Trompet, Stella, Mangino, Massimo, Kristiansson, Kati, Beekman, Marian, Lyytikainen, Leo-Pekka, Eriksson, Joel, Henneman, Peter, Lahti, Jari, Tanaka, Toshiko, Luan, Jian'an, Del Greco M, Fabiola, Pasko, Dorota, Renstrom, Frida, Willems, Sara M., Mahajan, Anubha ... Loos, Ruth J. F. (2016). Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels. Nature Communications, 7 10494. doi: 10.1038/ncomms10494 |
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2016 Journal Article The Combined Effect of Common Genetic Risk Variants on Circulating Lipoproteins Is Evident in Childhood: A Longitudinal Analysis of the Cardiovascular Risk in Young Finns StudyBuscot, Marie-jeanne, Magnussen, Costan G., Juonala, Markus, Pitkanen, Niina, Lehtimaki, Terho, Viikari, Jorma S. A., Kahonen, Mika, Hutri-Kahonen, Nina, Schork, Nicholas J., Raitakari, Olli T. and Thomson, Russell J. (2016). The Combined Effect of Common Genetic Risk Variants on Circulating Lipoproteins Is Evident in Childhood: A Longitudinal Analysis of the Cardiovascular Risk in Young Finns Study. Plos One, 11 (1) e0146081. doi: 10.1371/journal.pone.0146081 |
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2016 Journal Article Genome-wide association analysis identifies three new susceptibility loci for childhood body mass indexFelix, Janine F., Bradfield, Jonathan P., Monnereau, Claire, van der Valk, Ralf J. P., Stergiakouli, Evie, Chesi, Alessandra, Gaillard, Romy, Feenstra, Bjarke, Thiering, Elisabeth, Kreiner-Moller, Eskil, Mahajan, Anubha, Pitkanen, Niina, Joro, Raimo, Cavadino, Alana, Huikari, Ville, Franks, Steve, Groen-Blokhuis, Maria M., Cousminer, Diana L., Marsh, Julie A., Lehtimaki, Terho, Curtin, John A., Vioque, Jesus, Ahluwalia, Tarunveer S., Myhre, Ronny, Price, Thomas S., Vilor-Tejedor, Natalia, Yengo, Loic, Grarup, Niels, Ntalla, Ioanna ... Jaddoe, Vincent W. V. (2016). Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index. Human Molecular Genetics, 25 (2), 389-403. doi: 10.1093/hmg/ddv472 |
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2015 Journal Article Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputationArtigas, Maria Soler, Wain, Louise V., Miller, Suzanne, Kheirallah, Abdul Kader, Huffman, Jennifer E., Ntalla, Ioanna, Shrine, Nick, Obeidat, Ma'en, Trochet, Holly, McArdle, Wendy L., Alves, Alexessander Couto, Hui, Jennie, Zhao, Jing Hua, Joshi, Peter K., Teumer, Alexander, Albrecht, Eva, Imboden, Medea, Rawal, Rajesh, Lopez, Lorna M., Marten, Jonathan, Enroth, Stefan, Surakka, Ida, Polasek, Ozren, Lyytikainen, Leo-Pekka, Granell, Raquel, Hysi, Pirro G., Flexeder, Claudia, Mahajan, Anubha, Beilby, John ... Zeggini, Eleftheria (2015). Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation. Nature Communications, 6 (8658) 89658, 1-12. doi: 10.1038/ncomms9658 |
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2015 Journal Article Increased Body Mass Index in Parent-Child Dyads Predicts the Offspring Risk of Meeting Bariatric Surgery CriteriaJuonala, Markus, Sabin, Matthew A., Burgner, David, Cheung, Michael, Kahonen, Mika, Hutri-Kahonen, Nina, Lehtimaki, Terho, Jokinen, Eero, Koskinen, Juha, Tossavainen, Paivi, Laitinen, Tomi, Viikari, Jorma S. A., Raitakari, Olli T. and Magnussen, Costan G. (2015). Increased Body Mass Index in Parent-Child Dyads Predicts the Offspring Risk of Meeting Bariatric Surgery Criteria. Journal of Clinical Endocrinology & Metabolism, 100 (11), 4257-4263. doi: 10.1210/jc.2015-2524 |
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2015 Journal Article Coronary heart disease risk factors, coronary artery calcification and epicardial fat volume in the Young Finns StudyHartiala, Olli, Magnussen, Costan G., Bucci, Marco, Kajander, Sami, Knuuti, Juhani, Ukkonen, Heikki, Saraste, Antti, Rinta-Kiikka, Irina, Kainulainen, Sakari, Kahonen, Mika, Hutri-Kahonen, Nina, Laitinen, Tomi, Lehtimaki, Terho, Viikari, Jorma S. A., Hartiala, Jaakko, Juonala, Markus and Raitakari, Olli T. (2015). Coronary heart disease risk factors, coronary artery calcification and epicardial fat volume in the Young Finns Study. European Heart Journal-Cardiovascular Imaging, 16 (11), 1256-1263. doi: 10.1093/ehjci/jev085 |
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2015 Journal Article Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylationKato, Norihiro, Loh, Marie, Takeuchi, Fumihiko, Verweij, Niek, Wang, Xu, Zhang, Weihua, Kelly, Tanika N., Saleheen, Danish, Lehne, Benjamin, Leach, Irene Mateo, Drong, Alexander W., Abbott, James, Wahl, Simone, Tan, Sian-Tsung, Scott, William R., Campanella, Gianluca, Chadeau-Hyam, Marc, Afzal, Uzma, Ahluwalia, Tarunveer S., Bonder, Marc Jan, Chen, Peng, Dehghan, Abbas, Edwards, Todd L., Esko, Tonu, Go, Min Jin, Harris, Sarah E., Hartiala, Jaana, Kasela, Silva, Kasturiratne, Anuradhani ... Chambers, John C. (2015). Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation. Nature Genetics, 47 (11), 1282-+. doi: 10.1038/ng.3405 |
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2015 Journal Article The Biomarker GlycA Is Associated with Chronic Inflammation and Predicts Long-Term Risk of Severe InfectionRitchie, Scott C., Wurtz, Peter, Nath, Artika P., Abraham, Gad, Havulinna, Aki S., Fearnley, Liam G., Sarin, Antti-Pekka, Kangas, Antti J., Soininen, Pasi, Aalto, Kristiina, Seppala, Ilkka, Raitoharju, Emma, Salmi, Marko, Maksimow, Mikael, Mannisto, Satu, Kahonen, Mika, Juonala, Markus, Ripatti, Samuli, Lehtimaki, Terho, Jalkanen, Sirpa, Perola, Markus, Raitakari, Olli, Salomaa, Veikko, Ala-Korpela, Mika, Kettunen, Johannes and Inouye, Michael (2015). The Biomarker GlycA Is Associated with Chronic Inflammation and Predicts Long-Term Risk of Severe Infection. Cell Systems, 1 (4), 293-301. doi: 10.1016/j.cels.2015.09.007 |
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2015 Journal Article The influence of age and sex on genetic associations with adult body size and shape: a large-scale genome-wide interaction studyWinkler, Thomas W., Justice, Anne E., Graff, Mariaelisa, Barata, Llilda, Feitosa, Mary F., Chu, Su, Czajkowski, Jacek, Esko, Tonu, Fall, Tove, Kilpelainen, Tuomas O., Lu, Yingchang, Magi, Reedik, Mihailov, Evelin, Pers, Tune H., Rueeger, Sina, Teumer, Alexander, Ehret, Georg B., Ferreira, Teresa, Heard-Costa, Nancy L., Karjalainen, Juha, Lagou, Vasiliki, Mahajan, Anubha, Neinast, Michael D., Prokopenko, Inga, Simino, Jeannette, Teslovich, Tanya M., Jansen, Rick, Westra, Harm-Jan, White, Charles C. ... Loos, Ruth J. F. (2015). The influence of age and sex on genetic associations with adult body size and shape: a large-scale genome-wide interaction study. PL o S Genetics, 11 (10) e1005378, 1-42. doi: 10.1371/journal.pgen.1005378 |
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2015 Journal Article Subtle increases in heart size persist into adulthood in growth restricted babies: the Cardiovascular Risk in Young Finns StudyArnott, Clare, Skilton, Michael R., Ruohonen, Saku, Juonala, Markus, Viikari, Jorma S. A., Kahonen, Mika, Lehtimaki, Terho, Laitinen, Tomi, Celermajer, David S. and Raitakari, Olli T. (2015). Subtle increases in heart size persist into adulthood in growth restricted babies: the Cardiovascular Risk in Young Finns Study. Open Heart, 2 (1) UNSP e000265, e000265. doi: 10.1136/openhrt-2015-000265 |
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2015 Journal Article Molecular mechanisms underlying variations in lung function: a systems genetics analysisObeidat, Ma'en, Hao, Ke, Bosse, Yohan, Nickle, David C., Nie, Yunlong, Postma, Dirkje S., Laviolette, Michel, Sandford, Andrew J., Daley, Denise D., Hogg, James C., Elliott, W. Mark, Fishbane, Nick, Timens, Wim, Hysi, Pirro G., Kaprio, Jaakko, Wilson, James F., Hui, Jennie, Rawal, Rajesh, Schulz, Holger, Stubbe, Beate, Hayward, Caroline, Polasek, Ozren, Jarvelin, Marjo-Riitta, Zhao, Jing Hua, Jarvis, Deborah, Kahonen, Mika, Franceschini, Nora, North, Kari E., Loth, Daan W. ... Pare, Peter D. (2015). Molecular mechanisms underlying variations in lung function: a systems genetics analysis. Lancet Respiratory Medicine, 3 (10), 782-795. doi: 10.1016/S2213-2600(15)00380-X |
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2015 Journal Article Effect of fermented milk product containing lactotripeptides and plant sterol esters on haemodynamics in subjects with the metabolic syndrome - a randomised, double-blind, placebo-controlled studyHautaniemi, Elina J., Tikkakoski, Antti J., Tahvanainen, Anna, Nordhausen, Klaus, Kahonen, Mika, Mattsson, Tiina, Luhtala, Satu, Turpeinen, Anu M., Niemela, Onni, Vapaatalo, Heikki, Korpela, Riitta and Porsti, Ilkka H. (2015). Effect of fermented milk product containing lactotripeptides and plant sterol esters on haemodynamics in subjects with the metabolic syndrome - a randomised, double-blind, placebo-controlled study. British Journal of Nutrition, 114 (3), 376-386. doi: 10.1017/S0007114515002032 |
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2015 Journal Article Effect of birth weight on life-course blood pressure levels among children born premature: the Cardiovascular Risk in Young Finns StudyJuonala, Markus, Cheung, Michael M. H., Sabin, Matthew A., Burgner, David, Skilton, Michael R., Kahonen, Mika, Hutri-Kahonen, Nina, Lehtimaki, Terho, Jula, Antti, Laitinen, Tomi, Jokinen, Eero, Taittonen, Leena, Tossavainen, Paivi, Viikari, Jorma S. A., Magnussen, Costan G. and Raitakari, Olli T. (2015). Effect of birth weight on life-course blood pressure levels among children born premature: the Cardiovascular Risk in Young Finns Study. Journal of Hypertension, 33 (8), 1542-1548. doi: 10.1097/HJH.0000000000000612 |
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2015 Journal Article Vigorous physical activity and carotid distensibility in young and mid-aged adultsHuynh, Quan L., Blizzard, Christopher L., Raitakari, Olli, Sharman, James E., Magnussen, Costan G., Dwyer, Terence, Juonala, Markus, Kahonen, Mika and Venn, Alison J. (2015). Vigorous physical activity and carotid distensibility in young and mid-aged adults. Hypertension Research, 38 (5), 355-360. doi: 10.1038/hr.2015.9 |
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2015 Journal Article Lifetime measures of ideal cardiovascular health and their association with subclinical atherosclerosis: The Cardiovascular Risk in Young Finns StudyLaitinen, Tomi T., Pahkala, Katja, Magnussen, Costan G., Oikonen, Mervi, Viikari, Jorma S. A., Sabin, Matthew A., Daniels, Stephen R., Heinonen, Olli J., Taittonen, Leena, Hartiala, Olli, Mikkila, Vera, Hutri-Kahonen, Nina, Laitinen, Tomi, Kahonen, Mika, Raitakari, Olli T. and Juonala, Markus (2015). Lifetime measures of ideal cardiovascular health and their association with subclinical atherosclerosis: The Cardiovascular Risk in Young Finns Study. International Journal of Cardiology, 185, 186-191. doi: 10.1016/j.ijcard.2015.03.051 |
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2015 Journal Article Exposure to Parental Smoking in Childhood Is Associated With Increased Risk of Carotid Atherosclerotic Plaque in Adulthood The Cardiovascular Risk in Young Finns StudyWest, Henry W., Juonala, Markus, Gall, Seana L., Kahonen, Mika, Laitinen, Tomi, Taittonen, Leena, Viikari, Jorma S. A., Raitakari, Olli T. and Magnussen, Costan G. (2015). Exposure to Parental Smoking in Childhood Is Associated With Increased Risk of Carotid Atherosclerotic Plaque in Adulthood The Cardiovascular Risk in Young Finns Study. Circulation, 131 (14), 1239-1246. doi: 10.1161/CIRCULATIONAHA.114.013485 |
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2015 Journal Article Early childhood hospitalisation with infection and subclinical atherosclerosis in adulthood: The Cardiovascular Risk in Young Finns StudyBurgner, David P., Sabin, Matthew A., Magnussen, Costan G., Cheung, Michael, Sun, Cong, Kahonen, Mika, Hutri-Kahonen, Nina, Lehtimaki, Terho, Jokinen, Eero, Laitinen, Tomi, Viikari, Jorma S. A., Raitakari, Olli T. and Juonala, Markus (2015). Early childhood hospitalisation with infection and subclinical atherosclerosis in adulthood: The Cardiovascular Risk in Young Finns Study. Atherosclerosis, 239 (2), 496-502. doi: 10.1016/j.atherosclerosis.2015.02.024 |
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2015 Journal Article Childhood 25-OH Vitamin D Levels and Carotid Intima-Media Thickness in Adulthood: The Cardiovascular Risk in Young Finns StudyJuonala, Markus, Voipio, Atte, Pahkala, Katja, Viikari, Jorma S. A., Mikkila, Vera, Kahonen, Mika, Hutri-Kahonen, Nina, Jula, Antti, Burgner, David, Sabin, Matthew A., Marniemi, Jukka, Loo, Britt-Marie, Laitinen, Tomi, Jokinen, Eero, Taittonen, Leena, Magnussen, Costan G. and Raitakari, Olli T. (2015). Childhood 25-OH Vitamin D Levels and Carotid Intima-Media Thickness in Adulthood: The Cardiovascular Risk in Young Finns Study. Journal of Clinical Endocrinology & Metabolism, 100 (4), 1469-1476. doi: 10.1210/jc.2014-3944 |
