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2015 Journal Article Genetic variants in adult bone mineral density and fracture risk genes are associated with the rate of bone mineral density acquisition in adolescenceWarrington, Nicole M., Kemp, John P., Tilling, Kate, Tobias, Jonathan H. and Evans, David M. (2015). Genetic variants in adult bone mineral density and fracture risk genes are associated with the rate of bone mineral density acquisition in adolescence. Human Molecular Genetics, 24 (14) ddv143, 4158-4166. doi: 10.1093/hmg/ddv143 |
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2015 Journal Article A genome-wide association study of body mass index across early life and childhoodWarrington, Nicole M., Howe, Laura D., Paternoster, Lavinia, Kaakinen, Marika, Herrala, Sauli, Huikari, Ville, Wu, Yan Yan, Kemp, John P., Timpson, Nicholas J., Pourcain, Beate St, Smith, George Davey, Tilling, Kate, Jarvelin, Marjo-Riitta, Pennell, Craig E., Evans, David M., Lawlor, Debbie A., Briollais, Laurent and Palmer, Lyle J. (2015). A genome-wide association study of body mass index across early life and childhood. International Journal of Epidemiology, 44 (2) dyv077, 700-712. doi: 10.1093/ije/dyv077 |
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2015 Journal Article Shared genetic influences between attention-deficit/hyperactivity disorder (ADHD) traits in children and clinical ADHDStergiakouli, Evie, Martin, Joanna, Hamshere, Marian L., Langley, Kate, Evans, David M., St Pourcain, Beate, Timpson, Nicholas J., Owen, Michael J., O'Donovan, Michael, Thapar, Anita and Davey Smith, George (2015). Shared genetic influences between attention-deficit/hyperactivity disorder (ADHD) traits in children and clinical ADHD. Journal of the American Academy of Child and Adolescent Psychiatry, 54 (4), 322-327. doi: 10.1016/j.jaac.2015.01.010 |
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2015 Journal Article Cardiometabolic effects of genetic upregulation of the interleukin 1 receptor antagonist: A Mendelian randomisation analysisFreitag, Daniel, Butterworth, Adam S, Willeit, Peter, Howson, Joanna M M, Burgess, Stephen, Kaptoge, Stephen, Young, Robin, Ho, Weang Kee, Wood, Angela M, Sweeting, Michael, Spackman, Sarah, Staley, James R, Ramond, Anna, Harshfield, Eric, Nielsen, Sune F, Grande, Peer, Lange, Leslie A, Bown, Matthew J, Jones, Gregory T, Scott, Robert A, Bevan, Steve, Porcu, Eleonora, Thorleifsson, Gudmar, Zeng, Lingyao, Kessler, Thorsten, Nikpay, Majid, Do, Ron, Zhang, Weihua, Hopewell, Jemma C ... Houlston, Richard S (2015). Cardiometabolic effects of genetic upregulation of the interleukin 1 receptor antagonist: A Mendelian randomisation analysis. The Lancet Diabetes and Endocrinology, 3 (4), 243-253. doi: 10.1016/S2213-8587(15)00034-0 |
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2015 Journal Article Genome-wide association study of blood lead shows multiple associations near ALADWarrington, Nicole M., Zhu, Gu, Dy, Veronica, Heath, Andrew C., Madden, Pamela A. F., Hemani, Gibran, Kemp, John P., Mcmahon, George, St Pourcain, Beate, Timpson, Nicholas J., Taylor, Caroline M., Golding, Jean, Lawlor, Debbie A., Steer, Colin, Montgomery, Grant W., Martin, Nicholas G., Smith, George Davey, Evans, David M. and Whitfield, John B. (2015). Genome-wide association study of blood lead shows multiple associations near ALAD. Human Molecular Genetics, 24 (13) ddv112, 3871-3879. doi: 10.1093/hmg/ddv112 |
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2015 Journal Article Whole-genome sequence-based analysis of thyroid functionTaylor, Peter N., Porcu, Eleonora, Chew, Shelby, Campbell, Purdey J., Traglia, Michela, Brown, Suzanne J., Mullin, Benjamin H., Shihab, Hashem A., Min, Josine, Walter, Klaudia, Memari, Yasin, Huang, Jie, Barnes, Michael R., Beilby, John P., Charoen, Pimphen, Danecek, Petr, Dudbridge, Frank, Forgetta, Vincenzo, Greenwood, Celia, Grundberg, Elin, Johnson, Andrew D., Hui, Jennie, Lim, Ee M., McCarthy, Shane, Muddyman, Dawn, Panicker, Vijay, Perry, John R. B., Bell, Jordana T., Yuan, Wei ... Yang, Jian (2015). Whole-genome sequence-based analysis of thyroid function. Nature Communications, 6 (1) 5681, 5681.1-5681.10. doi: 10.1038/ncomms6681 |
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2015 Journal Article Genomic influences on alcohol problems in a population-based sample of young adultsEdwards, Alexis C., Aliev, Fazil, Wolen, Aaron R., Salvatore, Jessica E., Gardner, Charles O., McMahon, George, Evans, David M., Macleod, John, Hickman, Matthew, Dick, Danielle M. and Kendler, Kenneth S. (2015). Genomic influences on alcohol problems in a population-based sample of young adults. Addiction, 110 (3), 461-470. doi: 10.1111/add.12822 |
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2015 Journal Article A novel common variant in DCST2 is associated with length in early life and height in adulthoodvan der Valk, Ralf J. P., Kreiner-Moller, Eskil, Kooijman, Marjolein N., Guxens, Monica, Stergiakouli, Evangelia, Saaf, Annika, Bradfield, Jonathan P., Geller, Frank, Hayes, M. Geoffrey, Cousminer, Diana L., Koerner, Antje, Thiering, Elisabeth, Curtin, John A., Myhre, Ronny, Huikari, Ville, Joro, Raimo, Kerkhof, Marjan, Warrington, Nicole M., Pitkanen, Niina, Ntalla, Ioanna, Horikoshi, Momoko, Veijola, Riitta, Freathy, Rachel M., Teo, Yik-Ying, Barton, Sheila J., Evans, David M., Kemp, John P., St Pourcain, Beate, Ring, Susan M. ... for the Early Growth Genetics (EGG) Consortium (2015). A novel common variant in DCST2 is associated with length in early life and height in adulthood. Human Molecular Genetics, 24 (4) ddu510, 1155-1168. doi: 10.1093/hmg/ddu510 |
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2015 Journal Article Associations of vitamin D pathway genes with circulating 25-hydroxyvitamin-D, 1,25-dihydroxyvitamin-D, and prostate cancer: a nested case–control studyGilbert, Rebecca, Bonilla, Carolina, Metcalfe, Chris, Lewis, Sarah, Evans, David M., Fraser, William D., Kemp, John P., Donovan, Jenny L., Hamdy, Freddie C., Neal, David E., Lane, J. Athene, Smith, George Davey, Lathrop, Mark and Martin, Richard M. (2015). Associations of vitamin D pathway genes with circulating 25-hydroxyvitamin-D, 1,25-dihydroxyvitamin-D, and prostate cancer: a nested case–control study. Cancer Causes and Control, 26 (2), 205-218. doi: 10.1007/s10552-014-0500-5 |
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2015 Journal Article Assumption-free estimation of the genetic contribution to refractive error across childhoodGuggenheim, Jeremy A., St Pourcain, Beate, McMahon, George, Timpson, Nicholas J., Evans, David M. and Williams, Cathy (2015). Assumption-free estimation of the genetic contribution to refractive error across childhood. Molecular Vision, 21, 621-632. |
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2015 Journal Article Genetic dissection of acute anterior uveitis reveals similarities and differences in associations observed with ankylosing spondylitisRobinson, Philip C., Claushuis, Theodora A. M., Cortes, Adrian, Martin, Tammy M., Evans, David M., Leo, Paul, Mukhopadhyay, Pamela, Bradbury, Linda A., Cremin, Katie, Harris, Jessica, Maksymowych, Walter P., Inman, Robert D., Rahman, Proton, Haroon, Nigil, Gensler, Lianne, Powell, Joseph E., Van Der Horst-Bruinsma, Irene E., Hewitt, Alex W., Craig, Jamie E., Lim, Lyndell L., Wakefield, Denis, McCluskey, Peter, Voigt, Valentina, Fleming, Peter, Spondyloarthritis Research Consortium of Canada, Australio-Anglo-American Spondylitis Consortium, International Genetics of Ankylosing Spondylitis Consortium, Wellcome Trust Case Control Study 2, Degli-Esposti, Mariapia ... Brown, Matthew A. (2015). Genetic dissection of acute anterior uveitis reveals similarities and differences in associations observed with ankylosing spondylitis. Arthritis and Rheumatology, 67 (1), 140-151. doi: 10.1002/art.38873 |
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2015 Journal Article Mendelian randomization: new applications in the coming age of hypothesis free causalityEvans, David M. and Smith, George Davey (2015). Mendelian randomization: new applications in the coming age of hypothesis free causality. Annual Review of Genomics and Human Genetics, 16 (1), 327-350. doi: 10.1146/annurev-genom-090314-050016 |
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2014 Journal Article Heritability and genome-wide analyses of problematic peer relationships during childhood and adolescenceSt Pourcain, Beate, Haworth, C. M. A., Davis, O. S. P., Wang, Kai, Timpson, Nicholas J., Evans, David M., Kemp, John P., Ronald, Angelica, Price, Tom, Meaburn, Emma, Ring, Susan M., Golding, Jean, Hakonarson, Hakon, Plomin, R. and Smith, George Davey (2014). Heritability and genome-wide analyses of problematic peer relationships during childhood and adolescence. Human Genetics, 134 (6), 539-551. doi: 10.1007/s00439-014-1514-5 |
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2014 Journal Article Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: the CREAM consortiumLi, Qing, Wojciechowski, Robert, Simpson, Claire L., Hysi, Pirro G., Verhoeven, Virginie J. M., Ikram, Mohammad Kamran, Hohn, Rene, Vitart, Veronique, Hewitt, Alex W., Oexle, Konrad, Makela, Kari-Matti, MacGregor, Stuart, Pirastu, Mario, Fan, Qiao, Cheng, Ching-Yu, St Pourcain, Beate, McMahon, George, Kemp, John P., Northstone, Kate, Rahi, Jugnoo S., Cumberland, Phillippa M., Martin, Nicholas G., Sanfilippo, Paul G., Lu, Yi, Wang, Ya Xing, Hayward, Caroline, Polasek, Ozren, Campbell, Harry, Bencic, Goran ... Guggenheim, Jeremy A. (2014). Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: the CREAM consortium. Human Genetics, 134 (2), 131-146. doi: 10.1007/s00439-014-1500-y |
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2014 Journal Article Ankylosing spondylitis is associated with the anthrax toxin receptor 2 gene (ANTXR2)Karaderi, T., Keidel, S. M., Pointon, J. J., Appleton, L. H., Brown, M. A., Evans, D. M. and Wordsworth, B. P. (2014). Ankylosing spondylitis is associated with the anthrax toxin receptor 2 gene (ANTXR2). Annals of the Rheumatic Diseases, 73 (11), 2054-2058. doi: 10.1136/annrheumdis-2014-205643 |
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2014 Journal Article Genome-wide association study of height-adjusted BMI in childhood identifies functional variant in ADCY3Stergiakouli, Evangelia, Gaillard, Romy, Tavare, Jeremy M., Balthasar, Nina, Loos, Ruth J., Taal, Hendrik R., Evans, David M., Rivadeneira, Fernando, St Pourcain, Beate, Uitterlinden, Andre G., Kemp, John P., Hofman, Albert, Ring, Susan M., Cole, Tim J., Jaddoe, Vincent W.V., Smith, George Davey and Timpson, Nicholas J. (2014). Genome-wide association study of height-adjusted BMI in childhood identifies functional variant in ADCY3. Obesity, 22 (10), 2252-2259. doi: 10.1002/oby.20840 |
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2014 Journal Article A rare variant in APOC3 is associated with plasma triglyceride and VLDL levels in EuropeansTimpson, Nicholas J., Walter, Klaudia, Min, Josine L., Tachmazidou, Ioanna, Malerba, Giovanni, Shin, So-Youn, Chen, Lu, Futema, Marta, Southam, Lorraine, Iotchkova, Valentina, Cocca, Massimiliano, Huang, Jie, Memari, Yasin, McCarthy, Shane, Danecek, Petr, Muddyman, Dawn, Mangino, Massimo, Menni, Cristina, Perry, John R. B., Ring, Susan M., Gaye, Amadou, Dedoussis, George, Farmaki, Aliki-Eleni, Burton, Paul, Talmud, Philippa J., Gambaro, Giovanni, Spector, Tim D., Smith, George Davey, Durbin, Richard ... Yang, Jian (2014). A rare variant in APOC3 is associated with plasma triglyceride and VLDL levels in Europeans. Nature Communications, 5 (1) 4871, 1-10. doi: 10.1038/ncomms5871 |
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2014 Journal Article Common variation near ROBO2 is associated with expressive vocabulary in infancySt Pourcain, Beate, Cents, Rolieke A. M., Whitehouse, Andrew J. O., Haworth, Claire M. A., Davis, Oliver S. P., O'Reilly, Paul F., Roulstone, Susan, Wren, Yvonne, Ang, Qi W., Velders, Fleur P., Evans, David M., Kemp, John P., Warrington, Nicole M., Miller, Laura, Timpson, Nicholas J., Ring, Susan M., Verhulst, Frank C., Hofman, Albert, Rivadeneira, Fernando, Meaburn, Emma L., Price, Thomas S., Dale, Philip S., Pillas, Demetris, Yliherva, Anneli, Rodriguez, Alina, Golding, Jean, Jaddoe, Vincent W. V., Jarvelin, Marjo-Riitta, Plomin, Robert ... Smith, George Davey (2014). Common variation near ROBO2 is associated with expressive vocabulary in infancy. Nature Communications, 5 (1) A4831, 1-9. doi: 10.1038/ncomms5831 |
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2014 Journal Article Resolving the effects of maternal and offspring genotype on dyadic outcomes in genome wide complex trait analysis ("M-GCTA")Eaves, Lindon J., Pourcain, Beate St., Smith, George Davey, York, Timothy P. and Evans, David M. (2014). Resolving the effects of maternal and offspring genotype on dyadic outcomes in genome wide complex trait analysis ("M-GCTA"). Behavior Genetics, 44 (5), 445-455. doi: 10.1007/s10519-014-9666-6 |
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2014 Journal Article Genome-wide screening for DNA variants associated with reading and language traitsGialluisi, A., Newbury, D. F., Wilcutt, E. G., Olson, R. K., Defries, J. C., Brandler, W. M., Pennington, B. F., Smith, S. D., Scerri, T. S., Simpson, N. H., Luciano, M., Evans, D. M., Bates, T. C., Stein, J. F., Talcott, J. B., Monaco, A. P., Paracchini, S., Francks, C. and Fisher, S. E. (2014). Genome-wide screening for DNA variants associated with reading and language traits. Genes, Brain and Behavior, 13 (7), 686-701. doi: 10.1111/gbb.12158 |
