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2017 Journal Article Recent Developments in Mendelian Randomization StudiesZheng, Jie, Baird, Denis, Borges, Maria-Carolina, Bowden, Jack, Hemani, Gibran, Haycock, Philip, Evans, David M and Smith, George Davey (2017). Recent Developments in Mendelian Randomization Studies. Current epidemiology reports, 4 (4), 330-345. doi: 10.1007/s40471-017-0128-6 |
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2017 Journal Article Hair Cortisol in Twins: Heritability and Genetic Overlap with Psychological Variables and Stress-System GenesRietschel, Liz, Streit, Fabian, Zhu, Gu, McAloney, Kerrie, Frank, Josef, Couvy-Duchesne, Baptiste, Witt, Stephanie H., Binz, Tina M., Bolton, Jennifer L., Hayward, Caroline, Direk, Nese, Anderson, Anna, Huffman, Jennifer, Wilson, James F., Campbell, Harry, Rudan, Igor, Wright, Alan, Hastie, Nicholas, Wild, Sarah H., Velders, Fleur P., Hofman, Albert, Uitterlinden, Andre G., Lahti, Jari, Räikkönen, Katri, Kajantie, Eero, Widen, Elisabeth, Palotie, Aarno, Eriksson, Johan G., Kaakinen, Marika ... Rietschel, Marcella (2017). Hair Cortisol in Twins: Heritability and Genetic Overlap with Psychological Variables and Stress-System Genes. Scientific Reports, 7 (1) 15351, 15351. doi: 10.1038/s41598-017-11852-3 |
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2017 Journal Article Identification of atopic dermatitis subgroups in children from 2 longitudinal birth cohortsPaternoster, Lavinia, Savenije, Olga E.M., Heron, Jon, Evans, David M., Vonk, Judith M., Brunekreef, Bert, Wijga, Alet H., Henderson, A. John, Koppelman, Gerard H. and Brown, Sara J. (2017). Identification of atopic dermatitis subgroups in children from 2 longitudinal birth cohorts. Journal of Allergy and Clinical Immunology, 141 (3), 964-971. doi: 10.1016/j.jaci.2017.09.044 |
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2017 Journal Article Partitioning phenotypic variance due to parent-of-origin effects using genomic relatedness matricesLaurin, Charles, Cuellar-Partida, Gabriel, Hemani, Gibran, Smith, George Davey, Yang, Jian and Evans, David M. (2017). Partitioning phenotypic variance due to parent-of-origin effects using genomic relatedness matrices. Behavior Genetics, 48 (1), 67-79. doi: 10.1007/s10519-017-9880-0 |
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2017 Journal Article Maternal and fetal genetic contribution to gestational weight gainWarrington, N. M., Richmond, R., Fenstra, B., Myhre, R., Gaillard, R., Paternoster, L., Wang, C. A., Beaumont, R. N., Das, S., Murcia, M., Barton, S. J., Espinosa, A., Thiering, E., Atalay, M., Pitkänen, N., Ntalla, I., Jonsson, A. E., Freathy, R., Karhunen, V., Tiesler, C. M. T., Allard, C., Crawford, A., Ring, S. M., Melbye, M., Magnus, P., Rivadeneira, F., Skotte, L., Hansen, T., Marsh, J. ... Lawlor, D. A. (2017). Maternal and fetal genetic contribution to gestational weight gain. International Journal of Obesity (2005), 42 (4), 775-784. doi: 10.1038/ijo.2017.248 |
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2017 Journal Article Evaluation of shared genetic aetiology between osteoarthritis and bone mineral density identifies SMAD3 as a novel osteoarthritis risk locusHackinger, Sophie, Trajanoska, Katerina, Styrkarsdottir, Unnur, Zengini, Eleni, Steinberg, Julia, Ritchie, Graham R.S., Hatzikotoulas, Konstantinos, Gilly, Arthur, Evangelou, Evangelos, Kemp, John P., Evans, David, Ingvarsson, Thorvaldur, Jonsson, Helgi, Thorsteinsdottir, Unnur, Stefansson, Kari, McCaskie, Andrew W., Brooks, Roger A., Wilkinson, Jeremy M., Rivadeneira, Fernando and Zeggini, Eleftheria (2017). Evaluation of shared genetic aetiology between osteoarthritis and bone mineral density identifies SMAD3 as a novel osteoarthritis risk locus. Human Molecular Genetics, 26 (19), 3850-3858. doi: 10.1093/hmg/ddx285 |
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2017 Journal Article Developmental Changes Within the Genetic Architecture of Social Communication Behavior: A Multivariate Study of Genetic Variance in Unrelated IndividualsSt Pourcain, Beate, Eaves, Lindon J, Ring, Susan M, Fisher, Simon E, Medland, Sarah, Evans, David M and Davey Smith, George (2017). Developmental Changes Within the Genetic Architecture of Social Communication Behavior: A Multivariate Study of Genetic Variance in Unrelated Individuals. Biological psychiatry, 83 (7), 598-606. doi: 10.1016/j.biopsych.2017.09.020 |
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2017 Journal Article Collider scope: when selection bias can substantially influence observed associationsMunafò, Marcus R, Tilling, Kate, Taylor, Amy E, Evans, David M and Davey Smith, George (2017). Collider scope: when selection bias can substantially influence observed associations. International journal of epidemiology, 47 (1) dyx217, 226-235. doi: 10.1093/ije/dyx206 |
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2017 Journal Article Identification of 153 new loci associated with heel bone mineral density and functional involvement of GPC6 in osteoporosisKemp, John P., Morris, John A., Medina-Gomez, Carolina, Forgetta, Vincenzo, Warrington, Nicole M., Youlten, Scott E., Zheng, Jie, Gregson, Celia L., Grundberg, Elin, Trajanoska, Katerina, Logan, John G., Pollard, Andrea S., Sparkes, Penny C., Ghirardello, Elena J., Allen, Rebecca, Leitch, Victoria D., Butterfield, Natalie C., Komla-Ebri, Davide, Adoum, Anne-Tounsia, Curry, Katharine F., White, Jacqueline K., Kussy, Fiona, Greenlaw, Keelin M., Xu, Changjiang, Harvey, Nicholas C., Cooper, Cyrus, Adams, David J., Greenwood, Celia M. T., Maurano, Matthew T. ... Evans, David M. (2017). Identification of 153 new loci associated with heel bone mineral density and functional involvement of GPC6 in osteoporosis. Nature Genetics, 49 (10), 1468-1475. doi: 10.1038/ng.3949 |
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2017 Journal Article Back to school to protect against coronary heart disease?Richards, J. Brent and Evans, David M. (2017). Back to school to protect against coronary heart disease?. BMJ, 358 j3849, j3849. doi: 10.1136/bmj.j3849 |
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2017 Journal Article Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitnessWillems, Sara M., Wright, Daniel J., Day, Felix R., Trajanoska, Katerina, Joshi, Peter K., Morris, John A., Matteini, Amy M., Garton, Fleur C., Grarup, Niels, Oskolkov, Nikolay, Thalamuthu, Anbupalam, Mangino, Massimo, Liu, Jun, Demirkan, Ayse, Lek, Monkol, Xu, Liwen, Wang, Guan, Oldmeadow, Christopher, Gaulton, Kyle J., Lotta, Luca A., Miyamoto-Mikami, Eri, Rivas, Manuel A., White, Tom, Loh, Po-Ru, Aadahl, Mette, Amin, Najaf, Attia, John R., Austin, Krista, Benyamin, Beben ... Ohlsson, Claes (2017). Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness. Nature Communications, 8 (1) 16015, 16015. doi: 10.1038/ncomms16015 |
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2017 Journal Article Single Nucleotide Polymorphisms Associated with Reading Ability Show Connection to Socio-Economic OutcomesLuciano, Michelle, Hagenaars, Saskia P. , Cox, Simon R. , Hill, William David , Davies, Gail , Harris, Sarah E. , Deary, Ian J. , Evans, David M. , Martin, Nicholas G. , Wright, Margaret J. and Bates, Timothy C. (2017). Single Nucleotide Polymorphisms Associated with Reading Ability Show Connection to Socio-Economic Outcomes. Behavior Genetics, 47 (5), 469-479. doi: 10.1007/s10519-017-9859-x |
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2017 Journal Article Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locusMedina-Gomez, Carolina, Kemp, John P., Dimou, Niki L., Kreiner, Eskil, Chesi, Alessandra, Zemel, Babette S., Bonnelykke, Klaus, Boer, Cindy G., Ahluwalia, Tarunveer S., Bisgaard, Hans, Evangelou, Evangelos, Heppe, Denise H. M., Bonewald, Lynda F., Gorski, Jeffrey P., Ghanbari, Mohsen, Demissie, Serkalem, Duque, Gustavo, Maurano, Matthew T., Kiel, Douglas P., Hsu, Yi-Hsiang, Van Der Eerden, Bram C. J., Ackert-Bicknell, Cheryl, Reppe, Sjur, Gautvik, Kaare M., Raastad, Truls, Karasik, David, Van De Peppel, Jeroen, Jaddoe, Vincent W. V., Uitterlinden, André G. ... Rivadeneira, Fernando (2017). Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus. Nature Communications, 8 (1) 121, 121. doi: 10.1038/s41467-017-00108-3 |
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2017 Journal Article Association between telomere length and risk of cancer and non-neoplastic diseases a Mendelian randomization studyHaycock, Philip C., Burgess, Stephen, Nounu, Aayah, Zheng, Jie, Okoli, George N., Bowden, Jack, Wade, Kaitlin Hazel, Timpson, Nicholas J., Evans, David M., Willeit, Peter, Aviv, Abraham, Gaunt, Tomr., Hemani, Gibran, Mangino, Massimo, Ellis, Hayley Patricia, Kurian, Kathreena M., Pooley, Karen A., Eeles, Rosalind A., Lee, Jeffrey E., Fang, Shenying, Chen, Wei V., Law, Matthew H., Bowdler, Lisa M., Iles, Mark M., Yang, Qiong, Worrall, Bradford B., Markus, Hugh Stephen, Hung, Rayjean J., Amos, Chris I. ... Smith, George Davey (2017). Association between telomere length and risk of cancer and non-neoplastic diseases a Mendelian randomization study. JAMA Oncology, 3 (5), 636-651. doi: 10.1001/jamaoncol.2016.5945 |
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2017 Journal Article Epigenome-wide association of DNA methylation in whole blood with bone mineral densityMorris, John A., Tsai, Pei-Chien, Joehanes, Roby, Zeng, Jie, Trajanoska, Katerina, Soerensen, Mette, Forgetta, Vincenzo, Castillo-Fernandez, Juan Edgar, Frost, Morten, Spector, Tim D., Christensen, Kaare, Christiansen, Lene, Rivadeneira, Fernando, Tobias, Jonathan H., Evans, David M., Kiel, Douglas P., Hsu, Yi-Hsiang, Richards, J. Brent and Bell, Jordana T. (2017). Epigenome-wide association of DNA methylation in whole blood with bone mineral density. Journal of Bone and Mineral Research, 32 (8), 1644-1650. doi: 10.1002/jbmr.3148 |
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2017 Journal Article Pharmacogenetics of antidepressant response: a polygenic approachGarcía-González, Judit, Tansey, Katherine E., Hauser, Joanna, Henigsberg, Neven, Maier, Wolfgang, Mors, Ole, Placentino, Anna, Rietschel, Marcella, Souery, Daniel, Žagar, Tina, Czerski, Piotr M., Jerman, Borut, Buttenschøn, Henriette N., Schulze, Thomas G., Zobel, Astrid, Farmer, Anne, Aitchison, Katherine J., Craig, Ian, McGuffin, Peter, Giupponi, Michel, Perroud, Nader, Bondolfi, Guido, Evans, David, O'Donovan, Michael, Peters, Tim J., Wendland, Jens R., Lewis, Glyn, Kapur, Shitij, Perlis, Roy ... Fabbri, Chiara (2017). Pharmacogenetics of antidepressant response: a polygenic approach. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 75, 128-134. doi: 10.1016/j.pnpbp.2017.01.011 |
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2017 Journal Article Shared genetic influences between dimensional ASD and ADHD symptoms during child and adolescent developmentStergiakouli, Evie, Davey Smith, George, Martin, Joanna, Skuse, David H., Viechtbauer, Wolfgang, Ring, Susan M., Ronald, Angelica, Evans, David E., Fisher, Simon E., Thapar, Anita and St Pourcain, Beate (2017). Shared genetic influences between dimensional ASD and ADHD symptoms during child and adolescent development. Molecular Autism, 8 (1) 18, 18. doi: 10.1186/s13229-017-0131-2 |
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2017 Journal Article Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targetsWain, Louise V., Shrine, Nick, Artigas, María Soler, Erzurumluoglu, A. Mesut, Noyvert, Boris, Bossini-Castillo, Lara, Obeidat, Ma’en, Henry, Amanda P., Portelli, Michael A., Hall, Robert J., Billington, Charlotte K., Rimington, Tracy L., Fenech, Anthony G., John, Catherine, Blake, Tineka, Jackson, Victoria E., Allen, Richard J., Prins, Bram P., Campbell, Archie, Porteous, David J., Jarvelin, Marjo-Riitta, Wielscher, Matthias, James, Alan L., Hui, Jennie, Wareham, Nicholas J., Zhao, Jing Hua, Wilson, James F., Joshi, Peter K., Stubbe, Beate ... Tobin, Martin D. (2017). Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets. Nature Genetics, 49 (3), 416-425. doi: 10.1038/ng.3787 |
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2017 Journal Article Using Mendelian randomization to determine causal effects of maternal pregnancy (intrauterine) exposures on offspring outcomes: Sources of bias and methods for assessing themLawlor, Deborah, Richmond, Rebecca, Warrington, Nicole , McMahon, George, Davery Smith, George, Bowden, Jack and Evans, David M. (2017). Using Mendelian randomization to determine causal effects of maternal pregnancy (intrauterine) exposures on offspring outcomes: Sources of bias and methods for assessing them. Wellcome Open Research, 2 (11) 11, 11. doi: 10.12688/wellcomeopenres.10567.1 |
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2017 Journal Article LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysisZheng, Jie, Erzurumluoglu, A. Mesut, Elsworth, Benjamin L., Kemp, John P., Howe, Laurence, Haycock, Philip C., Hemani, Gibran, Tansey, Katherine, Laurin, Charles, St Pourcain, Beate, Warrington, Nicole M., Finucane, Hilary K., Price, Alkes L., Bulik-Sullivan, Brendan K., Anttila, Verneri, Paternoster, Lavinia, Gaunt, Tom R., Evans, David M. and Neale, Benjamin M. (2017). LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis. Bioinformatics, 33 (2), 272-279. doi: 10.1093/bioinformatics/btw613 |
