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Featured 2014 Journal Article ZAP-70 genotype disrupts the relationship between microbiota and host leading to spondyloarthritis and ileitis in SKG MiceRehaume, Linda, Mondot, Stanislas, Aguirre de Cárcer, Daniel, Velasco, Jared, Benham, Helen, Hasnain, Sumaira Zia, Bowman, Jaclyn, Ruutu, Merja, Hansbro, Philip M., McGuckin, Michael, Morrison, Mark and Thomas, Ranjeny (2014). ZAP-70 genotype disrupts the relationship between microbiota and host leading to spondyloarthritis and ileitis in SKG Mice. Arthritis and Rheumatology, 66 (10), 2780-2792. doi: 10.1002/art.38773 |
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2014 Journal Article Interleukin-23 mediates the intestinal response to microbial beta-glucan and the development of spondyloarthritis pathology in SKG miceBenham, Helen, Rehaume, Linda M., Hasnain, Sumaira Z., Velasco, Jared, Baillet, Athan C., Ruutu, Merja, Kikly, Kristine, Wang, Ran, Tseng, Hsu-Wen, Thomas, Gethin P., Brown, Matthew A., Strutton, Geoffrey, McGuckin, Michael A. and Thomas, Ranjeny (2014). Interleukin-23 mediates the intestinal response to microbial beta-glucan and the development of spondyloarthritis pathology in SKG mice. Arthritis and Rheumatology, 66 (7), 1755-1767. doi: 10.1002/art.38638 |
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2014 Conference Publication Human Neutrophil Elastase Activity and Matrix Metalloproteinase Activity Are Markers of Disease Severity in Non-Cf BronchiectasisChen, A., Lourie, R., Martin, M., Burr, L., Hasnain, S., Fantino, E., Bowler, S., Mcguckin, M. and Serisier, D. (2014). Human Neutrophil Elastase Activity and Matrix Metalloproteinase Activity Are Markers of Disease Severity in Non-Cf Bronchiectasis. Thoracic Society of Australia & New Zealand and the Australian & New Zealand Society of Respiratory Science 2014 Annual Scientific Meetings, Adelaide Australia, 4-9 April 2014. Richmond, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/resp.12263_6 |
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2014 Conference Publication Direct Adverse Effects of IL-23 on Epithelial Cells Underline Greater Efficacy of Neutralizing IL-23 in Suppressing Murine ColitisWang, Ran, Hasnain, Sumaira Z., Tong, Hui, Lourie, Rohan, Florin, Timothy H. and McGuckin, Michael A. (2014). Direct Adverse Effects of IL-23 on Epithelial Cells Underline Greater Efficacy of Neutralizing IL-23 in Suppressing Murine Colitis. 55th Annual Meeting of the Society for Surgery of the Alimentary Tract (SSAT) / Digestive Disease Week (DDW), Chicago, Il, United States, May 03-06, 2014. Maryland Heights, MO, United States: W.B. Saunders Co.. doi: 10.1016/S0016-5085(14)62987-5 |
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2014 Conference Publication IL-23 and IL-24 Upregulate Pro-Inflammatory Chemokine Genes in Colonic Epithelial CellsLourie, R., Hasnain, S. Z., McGuckin, M. A. and Florin, T. H. (2014). IL-23 and IL-24 Upregulate Pro-Inflammatory Chemokine Genes in Colonic Epithelial Cells. 103rd Annual Meeting of the United States and Canadian Academy of Pathology (USCAP), San Diego, California, 1-7 March 2014. London, United Kingdom: Nature Publishing Group. |
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2014 Conference Publication Clinical Benefits of Long-Term, Low-Dose Erythromycin in Bronchiectasis Are Not Due to Modulation of Sputum Mucin ContentChen, A., Martin, M., Lourie, R., Burr, L., Hasnain, S., Bowler, S., Mcguckin, M. and Serisier, D. (2014). Clinical Benefits of Long-Term, Low-Dose Erythromycin in Bronchiectasis Are Not Due to Modulation of Sputum Mucin Content. Annual Scientific Meeting of the Thoracic Society of Australia and New Zealand and the Australian and New Zealand Society of Respiratory Science 2014, Adelaide, SA Australia, 4-9 April 2014. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/resp.12263_6 |
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2014 Conference Publication IL-22 May Maintain Colonic Mucosal Barrier Function by Overriding ROS-Induced ER Stress and Chemokine Production in Colonic Epithelial CellsLourie, Rohan, Hasnain, Sumaira Z., McGuckin, Michael A. and Florin, Timothy H. (2014). IL-22 May Maintain Colonic Mucosal Barrier Function by Overriding ROS-Induced ER Stress and Chemokine Production in Colonic Epithelial Cells. Digestive Disease Week 2014, Chicago, Illinois, 3-6 May 2014. Maryland Heights, MO, United States: W.B. Saunders Co.. |
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2013 Conference Publication Administration Of E-Selectin Antagonist GMI-1271 Improves Survival After High-Dose Chemotherapy By Alleviating Mucositis and Accelerating Neutrophil RecoveryWinkler, Ingrid G., Barbier, Valerie, Nutt, Heather L., Hasnain, Sumaira Z., Levesque, Jean-Pierre, Magnani, John L. and McGuckin, Michael A. (2013). Administration Of E-Selectin Antagonist GMI-1271 Improves Survival After High-Dose Chemotherapy By Alleviating Mucositis and Accelerating Neutrophil Recovery. 55th Annual Meeting of the American-Society-of-Hematology, New Orleans La, Dec 07-10, 2013. WASHINGTON: AMER SOC HEMATOLOGY. |
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2013 Journal Article Glucocorticoids alleviate intestinal ER stress by enhancing protein folding and degradation of misfolded proteinsDas, Indrajit, Png, Chin Wen, Oancea, Iulia, Hasnain, Sumaira Z., Lourie, Rohan, Proctor, Martina, Eri, Rajaraman D., Sheng, Yong, Crane, Denis I., Florin, Timothy H. and McGuckin, Michael A. (2013). Glucocorticoids alleviate intestinal ER stress by enhancing protein folding and degradation of misfolded proteins. Journal of Experimental Medicine, 210 (6), 1201-1216. doi: 10.1084/jem.20121268 |
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2013 Journal Article IL-10 promotes production of intestinal mucus by suppressing protein misfolding and endoplasmic reticulum stress in goblet cellsHasnain, Sumaira Z., Tauro, Sharyn, Das, Indrajit, Tong, Hui, Chen, Alice C. -H., Jeffery, Penny L., McDonald, Victoria, Florin, Timothy H. and McGuckin, Michael A. (2013). IL-10 promotes production of intestinal mucus by suppressing protein misfolding and endoplasmic reticulum stress in goblet cells. Gastroenterology, 144 (2), 357-368. doi: 10.1053/j.gastro.2012.10.043 |
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2013 Journal Article There is a 'uc' in mucus, but is there mucus in UC?McGuckin, Michael A. and Hasnain, Sumaira Z. (2013). There is a 'uc' in mucus, but is there mucus in UC?. Gut, 63 (2), 216-217. doi: 10.1136/gutjnl-2013-304602 |
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2013 Journal Article A new role for mucins in immunity: insights from gastrointestinal nematode infectionHasnain, Sumaira Z., Gaagher, Amanda L., Grencis, Richard K. and Thornton, David J. (2013). A new role for mucins in immunity: insights from gastrointestinal nematode infection. International Journal of Biochemistry and Cell Biology, 45 (2), 364-374. doi: 10.1016/j.biocel.2012.10.011 |
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2013 Conference Publication Host Genetic Background Disrupts The Relationship Between Microbiota and Gut Mucosal Tolerance Leading To Spondyloarthritis and Ileitis After a Dectin-1 Trigger.Rehaume, Linda, Mondot, Stanislas, Aguirre de Cárcer, D., Velasco, Jared, Benham, Helen, Hasnain, Sumaira, Bowman, Jaclyn, Ruutu, Merja, Hansbro, Philip, McGuckin, Michael, Morrison, Mark and Thomas, Ranjeny (2013). Host Genetic Background Disrupts The Relationship Between Microbiota and Gut Mucosal Tolerance Leading To Spondyloarthritis and Ileitis After a Dectin-1 Trigger.. 77th Annual Meeting of the American College of Rheumatology / 48th Annual Meeting of the Association of Rheumatology Health Professionals, San Diego Ca, 25-30 October 2013. Hoboken, NJ United States: John Wiley and Sons Inc.. doi: 10.1002/art.38216 |
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2013 Conference Publication Incidence and Severity of Spondyloarthritis and Ileitis Are Determined by Interaction Between the Microbiota and Genetic Susceptibility in Beta-Glucan-Treated Skg MiceRehaume, L., Mondot, S., Aguirre de Cárcer, D., Velasco, J., Benham, H., Hasnain, S., Ruutu, M., McGuckin, M. and Morrison, M. (2013). Incidence and Severity of Spondyloarthritis and Ileitis Are Determined by Interaction Between the Microbiota and Genetic Susceptibility in Beta-Glucan-Treated Skg Mice. 54th Annual Scientific Meeting of the Australian Rheumatology Association in conjunction with the Rheumatology Health Professionals Association, Perth, WA Australia, 18 -22 May 2013. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/imj.12139 |
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2013 Conference Publication Innate defences at mucosal barriers: the anti-parasitic potential of the purified gastric mucin MUC5ACGallagher, A. L., Gonzalez, F. Melo, Rousseau, K., Hasnain, S. Z., Thornton, D. J. and Grencis, R. K. (2013). Innate defences at mucosal barriers: the anti-parasitic potential of the purified gastric mucin MUC5AC. Annual Congress of the British-Society-for-Immunology, Liverpool England, Dec 02-05, 2013. HOBOKEN: WILEY-BLACKWELL. |
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2013 Conference Publication Clinical Benefits Of Long-Term, Low-Dose Erythromycin In Bronchiectasis Are Not Due To Anti-Inflammatory EffectsChen, A. C., Martin, M. M., Burr, L., Hasnain, S. Z., Lourie, R., Bowler, S. D., McGuckin, M. A. and Serisier, D. J. (2013). Clinical Benefits Of Long-Term, Low-Dose Erythromycin In Bronchiectasis Are Not Due To Anti-Inflammatory Effects. American Thoracic Society 2013 International Conference, Philadelphia, Pennsylvania, 17-22 May 2013. New York, NY, United States: American Thoracic Society. |
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2012 Journal Article Serine protease(s) secreted by the nematode Trichuris muris degrade the mucus barrierHasnain, Sumaira Z., McGuckin, Michael A., Grencis, Richard K. and Thornton, David J. (2012). Serine protease(s) secreted by the nematode Trichuris muris degrade the mucus barrier. PLoS Neglected Tropical Diseases, 6 (10) e1856, e1856.1-e1856.13. doi: 10.1371/journal.pntd.0001856 |
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2012 Conference Publication Intestinal Endoplasmic Reticulum Stress is Modulated by Inflammatory CytokinesHasnain, Sumaira Z., Tauro, Sharyn, Jeffery, Penny, Das, Indrajit, Tran, Thu V., Florin, Timothy H. and McGuckin, Michael A. (2012). Intestinal Endoplasmic Reticulum Stress is Modulated by Inflammatory Cytokines. Digestive Disease Week (DDW), San Diego Ca, May 19-22, 2012. PHILADELPHIA: W B SAUNDERS CO-ELSEVIER INC. |
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2012 Journal Article The interplay between endoplasmic reticulum stress and inflammationHasnain, Sumaira Z ., Lourie, Rohan, Das, Indrajit, Chen, Alice C-H. and McGuckin, Michael A. (2012). The interplay between endoplasmic reticulum stress and inflammation. Immunology and Cell Biology, 90 (3), 260-270. doi: 10.1038/icb.2011.112 |
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2012 Book Chapter Techniques for assessment of interactions of mucins with microbes and parasites in vitro and in vivoSheng, Yong H., Hasnain, Sumaira Z, Png, Chin Wen, McGuckin, Michael A. and Lindén, Sara K. (2012). Techniques for assessment of interactions of mucins with microbes and parasites in vitro and in vivo. Mucins: Methods and Protocols. (pp. 297-312) edited by Michael A. McGuckin and David J. Thornton. New York, NY, United States: Humana Press. doi: 10.1007/978-1-61779-513-8_18 |
