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2021

Journal Article

DP1 prostanoid receptor activation increases the severity of an acute lower respiratory viral infection in mice via TNF-α-induced immunopathology

Ullah, Md Ashik, Rittchen, Sonja, Li, Jia, Hasnain, Sumaira Z. and Phipps, Simon (2021). DP1 prostanoid receptor activation increases the severity of an acute lower respiratory viral infection in mice via TNF-α-induced immunopathology. Mucosal Immunology, 14 (4), 963-972. doi: 10.1038/s41385-021-00405-7

DP1 prostanoid receptor activation increases the severity of an acute lower respiratory viral infection in mice via TNF-α-induced immunopathology

2021

Journal Article

A nucleotide analog prevents colitis associated cancer via Β-catenin independently of inflammation and autophagy

Sheng, Yong Hua, Giri, Rabina, Davies, Julie, Schreiber, Veronika, Alabbas, Saleh, Movva, Ramya, He, Yaowu, Wu, Andy, Hooper, John, McWhinney, Brett, Oancea, Iulia, Kijanka, Gregor, Hasnain, Sumaira, Lucke, Andrew J., Fairlie, David P., McGuckin, Michael A., Florin, Timothy H. and Begun, Jakob (2021). A nucleotide analog prevents colitis associated cancer via Β-catenin independently of inflammation and autophagy. Cellular and Molecular Gastroenterology and Hepatology, 11 (1), 33-53. doi: 10.1016/j.jcmgh.2020.05.012

A nucleotide analog prevents colitis associated cancer via Β-catenin independently of inflammation and autophagy

2021

Journal Article

Gut microbiota shape the inflammatory response in mice with an epithelial defect

Wang, Ran, Moniruzzaman, Md, Wong, Kuan Yau, Wiid, Percival, Harding, Alexa, Giri, Rabina, Tong, Wendy Hui, Creagh, Jackie, Begun, Jakob, McGuckin, Michael A. and Hasnain, Sumaira Z. (2021). Gut microbiota shape the inflammatory response in mice with an epithelial defect. Gut microbes, 13 (1), 1-18. doi: 10.1080/19490976.2021.1887720

Gut microbiota shape the inflammatory response in mice with an epithelial defect

2020

Journal Article

One‐pot synthesis of pH‐responsive eudragit‐mesoporous silica nanocomposites enable colonic delivery of glucocorticoids for the treatment of inflammatory bowel disease

Qu, Zhi, Wong, Kuan Yau, Moniruzzaman, Md., Begun, Jakob, Santos, Hélder A, Hasnain, Sumaira Z., Kumeria, Tushar, McGuckin, Michael A. and Popat, Amirali (2020). One‐pot synthesis of pH‐responsive eudragit‐mesoporous silica nanocomposites enable colonic delivery of glucocorticoids for the treatment of inflammatory bowel disease. Advanced Therapeutics, 4 (2) 2000165, 2000165. doi: 10.1002/adtp.202000165

One‐pot synthesis of pH‐responsive eudragit‐mesoporous silica nanocomposites enable colonic delivery of glucocorticoids for the treatment of inflammatory bowel disease

2020

Journal Article

Influence of the MUC1 cell surface mucin on gastric mucosal gene expression profiles in response to Helicobacter pylori infection in mice

Sheng, Yong H., Ng, Garrett Z., Summers, Kim M., Every, Alison L., Price, Gareth, Hasnain, Sumaira Z., Sutton, Philip and McGuckin, Michael A. (2020). Influence of the MUC1 cell surface mucin on gastric mucosal gene expression profiles in response to Helicobacter pylori infection in mice. Frontiers in Cellular and Infection Microbiology, 10 343, 343. doi: 10.3389/fcimb.2020.00343

Influence of the MUC1 cell surface mucin on gastric mucosal gene expression profiles in response to Helicobacter pylori infection in mice

2020

Journal Article

High glucose levels increase influenza-associated damage to the pulmonary epithelial-endothelial barrier

Hulme, Katina Dee, Yan, Limin, Marshall, Rebecca J., Bloxham, Conor J., Upton, Kyle R., Hasnain, Sumaira Z., Bielefeldt-Ohmann, Helle, Loh, Zhixuan, Ronacher, Katharina, Chew, Keng Yih , Gallo, Linda A. and Short, Kirsty Renfree (2020). High glucose levels increase influenza-associated damage to the pulmonary epithelial-endothelial barrier. eLife, 9 e56907, 1-20. doi: 10.7554/elife.56907

High glucose levels increase influenza-associated damage to the pulmonary epithelial-endothelial barrier

2020

Journal Article

Effect of Different Volumes of Interval Training and Continuous Exercise on Interleukin-22 in Adults with Metabolic Syndrome: A Randomized Trial

Ramos, Joyce S., Dalleck, Lance C., Stennett, Rebecca C., Mielke, Gregore I., Keating, Shelley E., Murray, Lydia S., Hasnain, Sumaira Z., Fassett, Robert G., McGuckin, Michael, Croci, Ilaria and Coombes, Jeff S. (2020). Effect of Different Volumes of Interval Training and Continuous Exercise on Interleukin-22 in Adults with Metabolic Syndrome: A Randomized Trial. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, 13, 2443-2453. doi: 10.2147/dmso.s251567

Effect of Different Volumes of Interval Training and Continuous Exercise on Interleukin-22 in Adults with Metabolic Syndrome: A Randomized Trial

2020

Journal Article

Airway mucus hyperconcentration in non–cystic fibrosis bronchiectasis

Ramsey, Kathryn A., Chen, Alice C. H., Radicioni, Giorgia, Lourie, Rohan, Martin, Megan, Broomfield, Amy, Sheng, Yong H., Hasnain, Sumaira Z., Radford-Smith, Graham, Simms, Lisa A., Burr, Lucy, Thornton, David J., Bowler, Simon D., Livengood, Stephanie, Ceppe, Agathe, Knowles, Michael R., Noone, Peadar G., Donaldson, Scott H., Hill, David B., Ehre, Camille, Button, Brian, Alexis, Neil E., Kesimer, Mehmet, Boucher, Richard C. and McGuckin, Michael A. (2020). Airway mucus hyperconcentration in non–cystic fibrosis bronchiectasis. American Journal of Respiratory and Critical Care Medicine, 201 (6), 661-670. doi: 10.1164/rccm.201906-1219OC

Airway mucus hyperconcentration in non–cystic fibrosis bronchiectasis

2020

Conference Publication

Blocking endogenous IL-22 is associated with reduced viral load and improved lung pathology in respiratory viral infections

Wang, R., Moniruzzaman, M., Wang, K., Upham, J. W., McGuckin, M., Phipps, S. and Hasnain, S. Z. (2020). Blocking endogenous IL-22 is associated with reduced viral load and improved lung pathology in respiratory viral infections. International Conference of the American-Thoracic-Society (ATS), Online, 10 November 2020. New York, NY, United States: American Thoracic Society. doi: 10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a6530

Blocking endogenous IL-22 is associated with reduced viral load and improved lung pathology in respiratory viral infections

2020

Conference Publication

Harnessing the therapeutic potential of interleukin-22 in neonatal respiratory viral infection

Hasnain, S., Wang, R., Taylor, S., Wong, K. Y., Moniruzzaman, M., Upham, J., Spann, K., Mcguckin, M. A., Burr, L. and Phipps, S. (2020). Harnessing the therapeutic potential of interleukin-22 in neonatal respiratory viral infection. TSANZSRS 2020 The Australia & New Zealand Society of Respiratory Science and The Thoracic Society of Australia and New Zealand (ANZSRS/TSANZ) Annual Scientific Meeting for Leaders in Lung Health & Respiratory Science, Melbourne, VIC, Australia, 27–31 March 2020. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/resp.13777

Harnessing the therapeutic potential of interleukin-22 in neonatal respiratory viral infection

2019

Journal Article

A cost-effective three-dimensional culture platform functionally mimics the adipose tissue microenvironment surrounding the kidney

Shen, Kunyu, Vesey, David A., Hasnain, Sumaira Z., Zhao, Kong-Nan, Wang, Haolu, Johnson, David W., Saunders, Nicholas, Burgess, Melinda and Gobe, Glenda C. (2019). A cost-effective three-dimensional culture platform functionally mimics the adipose tissue microenvironment surrounding the kidney. Biochemical and Biophysical Research Communications, 522 (3), 736-742. doi: 10.1016/j.bbrc.2019.11.119

A cost-effective three-dimensional culture platform functionally mimics the adipose tissue microenvironment surrounding the kidney

2019

Journal Article

Rationally designed dendritic silica nanoparticles for oral delivery of exenatide

Abeer, Muhammad Mustafa, Meka, Anand Kumar, Pujara, Naisarg, Kumeria, Tushar, Strounina, Ekaterina, Nunes, Rute, Costa, Ana, Sarmento, Bruno, Hasnain, Sumaira Z., Ross, Benjamin P. and Popat, Amirali (2019). Rationally designed dendritic silica nanoparticles for oral delivery of exenatide. Pharmaceutics, 11 (8) 418, 418. doi: 10.3390/pharmaceutics11080418

Rationally designed dendritic silica nanoparticles for oral delivery of exenatide

2019

Journal Article

MUC13 promotes the development of colitis-associated colorectal tumors via β-catenin activity

Sheng, Yong Hua, Wong, Kuan Yau, Seim, Inge, Wang, Ran, He, Yaowu, Wu, Andy, Patrick, Maya, Lourie, Rohan, Schreiber, Veronika, Giri, Rabina, Ng, Choa Ping, Popat, Amirali, Hooper, John, Kijanka, Gregor, Florin, Timothy H., Begun, Jakob, Radford, Kristen J., Hasnain, Sumaira and McGuckin, Michael A. (2019). MUC13 promotes the development of colitis-associated colorectal tumors via β-catenin activity. Oncogene, 38 (48), 7294-7310. doi: 10.1038/s41388-019-0951-y

MUC13 promotes the development of colitis-associated colorectal tumors via β-catenin activity

2019

Journal Article

Interleukin (IL)-22 from IL-20 Subfamily of cytokines induces colonic epithelial cell proliferation predominantly through ERK1/2 pathway

Moniruzzaman, Md., Wang, Ran, Jeet, Varinder, McGuckin, Michael A. and Hasnain, Sumaira Z. (2019). Interleukin (IL)-22 from IL-20 Subfamily of cytokines induces colonic epithelial cell proliferation predominantly through ERK1/2 pathway. International Journal of Molecular Sciences, 20 (14) 3468, 3468. doi: 10.3390/ijms20143468

Interleukin (IL)-22 from IL-20 Subfamily of cytokines induces colonic epithelial cell proliferation predominantly through ERK1/2 pathway

2019

Journal Article

Fibre intake is independently associated with increased circulating interleukin-22 in individuals with metabolic syndrome

Torquati, Luciana, Coombes, Jeff S., Murray, Lydia, Hasnain, Sumaira Z., Mallard, Alistair R., McGuckin, Michael A., Fassett, Robert G., Croci, Ilaria and Ramos, Joyce S. (2019). Fibre intake is independently associated with increased circulating interleukin-22 in individuals with metabolic syndrome. Nutrients, 11 (4) 815, 815. doi: 10.3390/nu11040815

Fibre intake is independently associated with increased circulating interleukin-22 in individuals with metabolic syndrome

2019

Journal Article

Interleukin-22: friend or foe?

Hasnain, Sumaira Z. and Begun, Jakob (2019). Interleukin-22: friend or foe?. Immunology and Cell Biology, 97 (4), 355-357. doi: 10.1111/imcb.12249

Interleukin-22: friend or foe?

2019

Conference Publication

Interleukin-20 subfamily cytokines in controlling intestinal inflammation and epithelial barrier integrity

Moniruzzaman, M., Wang, R., Wong, K., Tong, H., McGuckin, M. and Hasnain, S. (2019). Interleukin-20 subfamily cytokines in controlling intestinal inflammation and epithelial barrier integrity. Congress of ECCO, Copenhagen, Denmark, 6-9 March 2019. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/ecco-jcc/jjy222.044

Interleukin-20 subfamily cytokines in controlling intestinal inflammation and epithelial barrier integrity

2018

Conference Publication

Enteric microbiota shape the inflammatory response in mice with a Muc2 misfolding mutation

Wang, R., Giri, R., Moniruzzaman, M., Tong, H., Wong, K. Y., Begun, J., McGuckin, M. A. and Hasnain, S. Z. (2018). Enteric microbiota shape the inflammatory response in mice with a Muc2 misfolding mutation. Gastroenterological Society of Australia (GESA) Australian Gastroenterology Week (AGW) “Gut Matters”, Brisbane, QLD, Australia, 8-10 September 2018. Richmond, VIC, Australia: John Wiley & Sons.

Enteric microbiota shape the inflammatory response in mice with a Muc2 misfolding mutation

2018

Conference Publication

Interleukin-22: A potential therapy to control intestinal inflammation

Moniruzzaman, M., Wang, R., Wong, K. Y., Tong, H., McGuckin, M. A. and Hasnain, S. Z. (2018). Interleukin-22: A potential therapy to control intestinal inflammation. Gastroenterological Society of Australia (GESA) Australian Gastroenterology Week (AGW) “Gut Matters”, Brisbane, QLD, Australia, 8-10 September 2018. Richmond, VIC, Australia: John Wiley & Sons.

Interleukin-22: A potential therapy to control intestinal inflammation

2018

Journal Article

PPARγ is reduced in the airways of non-CF bronchiectasis subjects and is inversely correlated with the presence of Pseudomonas aeruginosa

Burr, Lucy D., Rogers, Geraint B., Chen, Alice C.-H., Taylor, Steven L., Bowler, Simon D., Keating, Rebecca L., Martin, Megan L., Hasnain, Sumaira Z. and McGuckin, Michael A. (2018). PPARγ is reduced in the airways of non-CF bronchiectasis subjects and is inversely correlated with the presence of Pseudomonas aeruginosa. PLoS ONE, 13 (8) e0202296, e0202296. doi: 10.1371/journal.pone.0202296

PPARγ is reduced in the airways of non-CF bronchiectasis subjects and is inversely correlated with the presence of Pseudomonas aeruginosa