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Dr Antiopi Varelias
Dr

Antiopi Varelias

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Overview

Background

Dr Antiopi Varelias leads the Transplantation Immunology laboratory at the QIMR Berghofer Medical Research Institute, Brisbane, Australia and is the Coordinator of the Immunology and Infectious diseases seminar series at the Institute. She was awarded her PhD from The University of Adelaide (Faculty of Medicine) in 2002 and held post-doctoral positions within the University of Adelaide’s Department of Surgery (TQEH) and Haematology/Oncology Unit, TQEH before moving to Brisbane to join the Bone Marrow Transplantation laboratory at QIMR Berghofer in 2008, at the time led by Professor Geoff Hill. Under Professor Hill’s mentorship, she has published many original research articles in peer-reviewed high-ranking journals on graft-versus-host disease and has presented her research findings at many international and national scientific meetings. As a chief investigator, she has been the recipient of funding from the NH&MRC and CCQ and is a member of several professional societies (ASTCT, TTS, TSANZ, AAI, ASI, SMI, ICIS).

Dr Varelias’s research interests focus on improving our fundamental understanding of the pathophysiology of graft-versus-host disease using innovative technologies and pre-clinical models, with the view of translating these findings into clinical practice and thereby provide better transplant outcomes for patients. Current research aims to define the immunological basis that underpins graft-versus-host disease, with an emphasis on cellular, cytokine and microbiome interactions that regulate mucosal immunity during stem cell transplantation.

Availability

Dr Antiopi Varelias is:
Available for supervision

Works

Search Professor Antiopi Varelias’s works on UQ eSpace

47 works between 2010 and 2024

41 - 47 of 47 works

2013

Journal Article

Induced regulatory T cells promote tolerance when stabilized by rapamycin and IL-2 in vivo

Zhang, Ping, Tey, Siok-Keen, Koyama, Motoko, Kuns, Rachel D., Olver, Stuart D., Lineburg, Katie E., Lor, Mary, Teal, Bianca E., Raffelt, Neil C., Raju, Jyothy, Leveque, Lucie, Markey, Kate A., Varelias, Antiopi, Clouston, Andrew D., Lane, Steven W., Macdonald, Kelli P. A. and Hill, Geoffrey R. (2013). Induced regulatory T cells promote tolerance when stabilized by rapamycin and IL-2 in vivo. Journal of Immunology, 191 (10), 5291-5303. doi: 10.4049/jimmunol.1301181

Induced regulatory T cells promote tolerance when stabilized by rapamycin and IL-2 in vivo

2013

Journal Article

Promoting regulation via the inhibition of DNAM-1 after transplantation

Koyama, Motoko, Kuns, Rachel D., Olver, Stuart D., Lineburg, Katie E., Lor, Mary, Teal, Bianca E., Raffelt, Neil C., Leveque, Lucie, Chan, Christopher J., Robb, Renee J., Markey, Kate A., Alexander, Kylie A., Varelias, Antiopi, Clouston, Andrew D., Smyth, Mark J., MacDonald, Kelli P.A. and Hill, Geoffrey R. (2013). Promoting regulation via the inhibition of DNAM-1 after transplantation. Blood, 121 (17), 3511-3520. doi: 10.1182/blood-2012-07-444026

Promoting regulation via the inhibition of DNAM-1 after transplantation

2012

Journal Article

Immune insufficiency during GVHD is due to defective antigen presentation within dendritic cell subsets

Markey, Kate A., Koyama, Motoko, Kuns, Rachel D., Lineburg, Katie E., Wilson, Yana A., Olver, Stuart D., Raffelt, Neil C., Don, Alistair L. J., Varelias, Antiopi, Robb, Renee J., Cheong, Melody, Engwerda, Christian R., Steptoe, Raymond J., Ramshaw, Hayley S., Lopez, Angel F., Vega-Ramos, Javier, Lew, Andrew M., Villadangos, Jose A., Hill, Geoffrey R. and MacDonald, Kelli P. A. (2012). Immune insufficiency during GVHD is due to defective antigen presentation within dendritic cell subsets. Blood, 119 (24), 5918-5930. doi: 10.1182/blood-2011-12-398164

Immune insufficiency during GVHD is due to defective antigen presentation within dendritic cell subsets

2012

Journal Article

Identification and expansion of highly suppressive CD8 +FoxP3 + regulatory T cells after experimental allogeneic bone marrow transplantation

Robb, R.J., Lineburg, K.E., Kuns, R.D., Wilson, Y.A., Raffelt, N.C., Olver, S.D., Varelias, A., Alexander, K.A., Teal, B.E., Sparwasser, T., Hammerling, G.J., Markey, K.A., Koyama, M., Clouston, A.D., Engwerda, C.R., Hill, G.R. and MacDonald, K.P.A. (2012). Identification and expansion of highly suppressive CD8 +FoxP3 + regulatory T cells after experimental allogeneic bone marrow transplantation. Blood, 119 (24), 5898-5908. doi: 10.1182/blood-2011-12-396119

Identification and expansion of highly suppressive CD8 +FoxP3 + regulatory T cells after experimental allogeneic bone marrow transplantation

2012

Journal Article

Recipient nonhematopoietic antigen-presenting cells are sufficient to induce lethal acute graft-versus-host disease

Koyama, Motoko, Kuns, Rachel D., Olver, Stuart D., Raffelt, Neil C., Wilson, Yana A., Don, Alistair L. J., Lineburg, Katie E., Cheong, Melody, Robb, Renee J., Markey, Kate A., Varelias, Antiopi, Malissen, Bernard, Hammerling, Gunter J., Clouston, Andrew D., Engwerda, Christian R., Bhat, Purnima, MacDonald, Kelli P. A. and Hill, Geoffrey R. (2012). Recipient nonhematopoietic antigen-presenting cells are sufficient to induce lethal acute graft-versus-host disease. Nature Medicine, 18 (1), 135-142. doi: 10.1038/nm.2597

Recipient nonhematopoietic antigen-presenting cells are sufficient to induce lethal acute graft-versus-host disease

2011

Journal Article

Type I-IFNs control GVHD and GVL responses after transplantation

Robb, Renee J., Kreijveld, Ellen, Kuns, Rachel D., Wilson, Yana A., Olver, Stuart D., Don, Alistair L. J., Raffelt, Neil C., De Weerd, Nicole A., Lineburg, Katie E., Varelias, Antiopi, Markey, Kate A., Koyama, Motoko, Clouston, Andrew D., Hertzog, Paul J., MacDonald, Kelli P. A. and Hill, Geoffrey R. (2011). Type I-IFNs control GVHD and GVL responses after transplantation. Blood, 118 (12), 3399-3409. doi: 10.1182/blood-2010-12-325746

Type I-IFNs control GVHD and GVL responses after transplantation

2010

Journal Article

Stem cell mobilization with G-CSF induces type 17 differentiation and promotes scleroderma

Hill, Geoffrey R., Olver, Stuart D., Kuns, Rachel D., Varelias, Antiopi, Raffelt, Neil C., Don, Alistair L., Markey, Kate A., Wilson, Yana A., Smyth, Mark J., Iwakura, Yoichiro, Tocker, Joel, Clouston, Andrew D. and MacDonald, Kelli P. A. (2010). Stem cell mobilization with G-CSF induces type 17 differentiation and promotes scleroderma. Blood, 116 (5), 819-828. doi: 10.1182/blood-2009-11-256495

Stem cell mobilization with G-CSF induces type 17 differentiation and promotes scleroderma

Supervision

Availability

Dr Antiopi Varelias is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    Defining the critical determinants of viral-mediated pneumonitis after bone marrow transplantation.

    Principal Advisor

    Other advisors: Dr Quan Nguyen, Dr Seweryn Bialasiewicz

  • Doctor Philosophy

    Pathogenic and Protective Cytokine Interactions in Graft-versus-Host Disease

    Associate Advisor

Completed supervision

  • 2021

    Doctor Philosophy

    Classification and functional characterisation of the murine gut bacterial family Muribaculaceae

    Associate Advisor

    Other advisors: Professor Phil Hugenholtz

Media

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