
Overview
Background
I am a genetic epidemiologist specialising in the genetics of neurodegenerative diseases, with a particular focus on Parkinson’s disease, chronic pain, and other age-related conditions. I lead a dynamic team of scientists dedicated to understanding how genetic and environmental factors influence neurodegeneration, brain health, and related health outcomes. My research is interdisciplinary, integrating advanced statistical genetics, bioinformatics, and data science to unravel disease mechanisms, improve patient stratification, and identify potential therapeutic targets.
In 2020, I founded the Australian Parkinson’s Genetics Study (APGS), now the largest Parkinson’s cohort in Australia with over 10,000 participants. This landmark study has positioned Australia as a key contributor to global Parkinson’s genetics research. I am also actively involved in the Global Parkinson’s Genetics Program (GP2), where I contribute to large-scale data analysis and work within the underrepresented populations working group to enhance diversity in genetic research worldwide.
Committed to training the next generation of researchers, I have supervised over 16 students, including several PhD candidates who have gone on to successful careers in academia and industry. Two of my recent PhD graduates received the Outstanding Thesis Award, and another received the AIPS Florey Next Generation Award.
I have published consistently in prominent journals, including Nature, Nature Genetics, Nature Communications, BRAIN, Biological Psychiatry, and SLEEP. To date, I have authored over 100 academic articles, which have been widely cited, and I have secured competitive funding from NHMRC, MRFF, The Michael J. Fox Foundation for Parkinson’s Research, Shake It Up Australia Foundation, the US National Institutes of Health, and the Alzheimer’s Association. My work has been recognised with several prestigious awards, including the 2023 Al & Val Rosenstrauss Fellowship from the Rebecca L Cooper Medical Research Foundation, the 2021 Enrico Greppi International Migraine Research Award, and the 2024 Adele Green Emerging Leader Award from QIMR Berghofer Medical Research Institute. I am also a Global Atlantic Fellow for Equity in Brain Health, a program by the University of California San Francisco and Trinity College Dublin, which supports my commitment to promoting brain health equity worldwide.
Availability
- Associate Professor Miguel Rentería is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Bachelor (Honours) of Genomics, Universidad Nacional Autónoma de México (UNAM)
- Doctor of Philosophy of Genetics, The University of Queensland
- Masters (Coursework) of Public Policy, University of Oxford
Works
Search Professor Miguel Rentería’s works on UQ eSpace
2022
Journal Article
Systematic Review: microRNAs as Potential Biomarkers in Mild Cognitive Impairment Diagnosis
Ogonowski, Natalia, Salcidua, Stefanny, Leon, Tomas, Chamorro-Veloso, Nayaret, Valls, Cristian, Avalos, Constanza, Bisquertt, Alejandro, Rentería, Miguel E., Orellana, Paulina and Duran-Aniotz, Claudia (2022). Systematic Review: microRNAs as Potential Biomarkers in Mild Cognitive Impairment Diagnosis. Frontiers in Aging Neuroscience, 13 807764, 807764. doi: 10.3389/fnagi.2021.807764
2021
Journal Article
Genetic basis to structural grey matter associations with chronic pain
Farrell, Scott F, Campos, Adrián I, Kho, Pik-Fang, de Zoete, Rutger M J, Sterling, Michele, Rentería, Miguel E, Ngo, Trung Thanh and Cuéllar-Partida, Gabriel (2021). Genetic basis to structural grey matter associations with chronic pain. Brain, 144 (12), 3611-3622. doi: 10.1093/brain/awab334
2021
Journal Article
Phenome-wide analysis highlights putative causal relationships between self-reported migraine and other complex traits
García-Marín, Luis M., Campos, Adrián I., Martin, Nicholas G., Cuéllar-Partida, Gabriel and Rentería, Miguel E. (2021). Phenome-wide analysis highlights putative causal relationships between self-reported migraine and other complex traits. Journal of Headache and Pain, 22 (1) 66, 66. doi: 10.1186/s10194-021-01284-w
2021
Journal Article
Large-scale genetic investigation reveals genetic liability to multiple complex traits influencing a higher risk of ADHD
García-Marín, Luis M., Campos, Adrián I., Cuéllar-Partida, Gabriel, Medland, Sarah E., Kollins, Scott H. and Rentería, Miguel E. (2021). Large-scale genetic investigation reveals genetic liability to multiple complex traits influencing a higher risk of ADHD. Scientific Reports, 11 (1) 22628, 22628. doi: 10.1038/s41598-021-01517-7
2021
Journal Article
Suicidal ideation and planning among Mexican adolescents are associated with depression polygenic risk scores
Martinez‐Levy, Gabriela A., Campos, Adrian I., Rabinowitz, Jill A., García‐Marín, Luis M., Benjet, Corina, Méndez, Enrique, Rentería, Miguel E. and Cruz‐Fuentes, Carlos S. (2021). Suicidal ideation and planning among Mexican adolescents are associated with depression polygenic risk scores. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 186 (8) ajmg.b.32864, 476-484. doi: 10.1002/ajmg.b.32864
2021
Journal Article
Understanding the effect of smoking and drinking behavior on Parkinson's disease risk: a Mendelian randomization study
Domínguez-Baleón, Carmen, Ong, Jue-Sheng, Scherzer, Clemens R., Rentería, Miguel E. and Dong, Xianjun (2021). Understanding the effect of smoking and drinking behavior on Parkinson's disease risk: a Mendelian randomization study. Scientific Reports, 11 (1) 13980. doi: 10.1038/s41598-021-93105-y
2021
Journal Article
Understanding genetic risk factors for common side effects of antidepressant medications
Campos, Adrian I., Mulcahy, Aoibhe, Thorp, Jackson G., Wray, Naomi R., Byrne, Enda M., Lind, Penelope A., Medland, Sarah E., Martin, Nicholas G., Hickie, Ian B. and Rentería, Miguel E. (2021). Understanding genetic risk factors for common side effects of antidepressant medications. Communications Medicine, 1 (1) 45, 1-10. doi: 10.1038/s43856-021-00046-8
2021
Journal Article
Identifying complex lncRNA/Pseudogene–miRNA–mRNA crosstalk in hormone-dependent cancers
Jayarathna, Dulari K., Rentería, Miguel E., Sauret, Emilie, Batra, Jyotsna and Gandhi, Neha S. (2021). Identifying complex lncRNA/Pseudogene–miRNA–mRNA crosstalk in hormone-dependent cancers. Biology, 10 (10) 1014, 1014. doi: 10.3390/biology10101014
2021
Journal Article
Factors that affect patient attrition in buprenorphine treatment for opioid use disorder: a retrospective real-world study using electronic health records
Ker, Sheryl, Hsu, Jennifer, Balani, Anisha, Mukherjee, Sankha Subhra, Rush, A John, Khan, Mehreen, Elchehabi, Sara, Huffhines, Seth, DeMoss, Dustin, Rentería, Miguel E and Sarkar, Joydeep (2021). Factors that affect patient attrition in buprenorphine treatment for opioid use disorder: a retrospective real-world study using electronic health records. Neuropsychiatric Disease and Treatment, 17, 3229-3244. doi: 10.2147/ndt.s331442
2021
Other Outputs
Structural brain alterations associated with suicidal thoughts and behaviors in young people: results across 21 international studies from the ENIGMA Suicidal Thoughts and Behaviours consortium
van Velzen, Laura S., Dauvermann, Maria R., Colic, Lejla, Villa, Luca M., Savage, Hannah S., Toenders, Yara J., Zhu, Alyssa H., Bright, Joanna K., Campos, Adrián I., Salminen, Lauren, Ambrogi, Sonia, Ayesa-Arriola, Rosa, Banaj, Nerisa, Başgöze, Zeynep, Bauer, Jochen, Blair, Karina, Blair, Robert James, Brosch, Katharina, Cheng, Yuqi, Colle, Romain, Connolly, Colm G., Corruble, Emmanuelle, Couvy-Duchesne, Baptiste, Crespo-Facorro, Benedicto, Cullen, Kathryn R., Dannlowski, Udo, Davey, Christopher G., Dohm, Katharina, Fullerton, Janice M. ... Schmaal, Lianne (2021). Structural brain alterations associated with suicidal thoughts and behaviors in young people: results across 21 international studies from the ENIGMA Suicidal Thoughts and Behaviours consortium. doi: 10.1101/2021.09.27.21264068
2021
Journal Article
Transcriptome-based polygenic score links depression-related corticolimbic gene expression changes to sex-specific brain morphology and depression risk
Miles, Amy E., Dos Santos, Fernanda C., Byrne, Enda M., Renteria, Miguel E., McIntosh, Andrew M., Adams, Mark J., Pistis, Giorgio, Castelao, Enrique, Preisig, Martin, Baune, Bernhard T., Schubert, K. Oliver, Lewis, Cathryn M., Jones, Lisa A., Jones, Ian, Uher, Rudolf, Smoller, Jordan W., Perlis, Roy H., Levinson, Douglas F., Potash, James B., Weissman, Myrna M., Shi, Jianxin, Lewis, Glyn, Penninx, Brenda W. J. H., Boomsma, Dorret I., Hamilton, Steven P., Sibille, Etienne, Hariri, Ahmad R., Nikolova, Yuliya S. and Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (2021). Transcriptome-based polygenic score links depression-related corticolimbic gene expression changes to sex-specific brain morphology and depression risk. Neuropsychopharmacology, 46 (13), 2304-2311. doi: 10.1038/s41386-021-01189-x
2021
Journal Article
Integrative transcriptome-wide analyses uncover novel risk-associated MicroRNAs in hormone-dependent cancers
Jayarathna, Dulari K., Rentería, Miguel E., Malik, Adil, Sauret, Emilie, Batra, Jyotsna and Gandhi, Neha S. (2021). Integrative transcriptome-wide analyses uncover novel risk-associated MicroRNAs in hormone-dependent cancers. Frontiers in Genetics, 12 716236. doi: 10.3389/fgene.2021.716236
2021
Journal Article
Genetic susceptibility to pneumonia: a GWAS meta-analysis between the UK Biobank and FinnGen
Campos, Adrian I., Kho, Pik, Vazquez-Prada, Karla X., García-Marín, Luis M., Martin, Nicholas G., Cuéllar-Partida, Gabriel and Rentería, Miguel E. (2021). Genetic susceptibility to pneumonia: a GWAS meta-analysis between the UK Biobank and FinnGen. Twin Research and Human Genetics, 24 (3) PII S183242742100027X, 145-154. doi: 10.1017/thg.2021.27
2021
Other Outputs
Understanding genetic risk factors for common side effects of antidepressant medications
Campos, Adrian I., Mulcahy, Aoibhe, Thorp, Jackson G., Wray, Naomi R., Byrne, Enda M., Lind, Penelope A., Medland, Sarah E., Martin, Nicholas G., Hickie, Ian B. and Rentería, Miguel E. (2021). Understanding genetic risk factors for common side effects of antidepressant medications. doi: 10.1101/2021.07.12.21260397
2021
Journal Article
Genetic risk for chronic pain is associated with lower antidepressant effectiveness: converging evidence for a depression subtype
Campos, Adrián I., Ngo, Trung Thanh, Medland, Sarah E., Wray, Naomi R., Hickie, Ian B., Byrne, Enda M., Martin, Nicholas G. and Rentería, Miguel E. (2021). Genetic risk for chronic pain is associated with lower antidepressant effectiveness: converging evidence for a depression subtype. Australian and New Zealand Journal of Psychiatry, 56 (9) 00048674211031491, 1-10. doi: 10.1177/00048674211031491
2021
Journal Article
Genetic propensity for risky behavior and depression and risk of lifetime suicide attempt among urban African Americans in adolescence and young adulthood
Rabinowitz, Jill A., Jin, Jin, Kahn, Geoffrey, Kuo, Sally I.‐Chun, Campos, Adrian, Renteria, Miguel, Benke, Kelly, Wilcox, Holly, Ialongo, Nicholas S., Maher, Brion S., Kertes, Darlene, Eaton, William, Uhl, George, Wagner, Barry M. and Cohen, Daniel (2021). Genetic propensity for risky behavior and depression and risk of lifetime suicide attempt among urban African Americans in adolescence and young adulthood. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 186 (8) ajmg.b.32866, 456-468. doi: 10.1002/ajmg.b.32866
2021
Journal Article
Phenome-wide screening of GWAS data reveals the complex causal architecture of obesity
García-Marín, Luis M., Campos, Adrián I., Kho, Pik-Fang, Martin, Nicholas G., Cuéllar-Partida, Gabriel and Rentería, Miguel E. (2021). Phenome-wide screening of GWAS data reveals the complex causal architecture of obesity. Human Genetics, 140 (8), 1253-1265. doi: 10.1007/s00439-021-02298-9
2021
Conference Publication
Structural Brain Alterations Associated With Suicidal Ideation and Attempt: Mega-Analytic Results Across 37 International Studies
van Velzen, Laura, Jahanshad, Neda, Campos, Adrian, Salminen, Lauren, Renteria, Miguel and Schmaal, Lianne (2021). Structural Brain Alterations Associated With Suicidal Ideation and Attempt: Mega-Analytic Results Across 37 International Studies. Society of Biological Psychiatry’s 2021 Annual Scientific Convention and Meeting, New Orleans, LA United States, 28-30 April 2022. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.biopsych.2021.02.072
2021
Journal Article
Comorbid chronic pain and depression: shared risk factors and differential antidepressant effectiveness
Roughan, William H., Campos, Adrián I., García-Marín, Luis M., Cuéllar-Partida, Gabriel, Lupton, Michelle K., Hickie, Ian B., Medland, Sarah E., Wray, Naomi R., Byrne, Enda M., Ngo, Trung Thanh, Martin, Nicholas G. and Rentería, Miguel E. (2021). Comorbid chronic pain and depression: shared risk factors and differential antidepressant effectiveness. Frontiers in Psychiatry, 12 643609, 1-13. doi: 10.3389/fpsyt.2021.643609
2021
Other Outputs
Shared genetic etiology between cortical brain morphology and tobacco, alcohol, and cannabis use
Rabinowitz, Jill A., Campos, Adrian I., Ong, Jue-Sheng, García-Marín, Luis M., Alcauter, Sarael, Mitchell, Brittany L., Grasby, Katrina S., Cuéllar-Partida, Gabriel, Gillespie, Nathan A., Huhn, Andrew S., Martin, Nicholas G., Thompson, Paul M., Medland, Sarah E., Maher, Brion S. and Rentería, Miguel E. (2021). Shared genetic etiology between cortical brain morphology and tobacco, alcohol, and cannabis use. doi: 10.1101/2021.03.28.21254282
Supervision
Availability
- Associate Professor Miguel Rentería is:
- Available for supervision
Before you email them, read our advice on how to contact a supervisor.
Supervision history
Current supervision
-
Doctor Philosophy
Monogenic Parkinson's disease among individuals from underrepresented backgrounds in Australia and Mexico
Principal Advisor
-
Doctor Philosophy
Elucidating the genetic architecture of neuropsychiatric phenotypes and other complex human traits
Principal Advisor
Other advisors: Professor Nick Martin
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Doctor Philosophy
Elucidating the genetic architecture of neuropsychiatric phenotypes and other complex human traits
Principal Advisor
Other advisors: Professor Nick Martin
-
Doctor Philosophy
Elucidating the genetic architecture of neuropsychiatric phenotypes and other complex human traits
Principal Advisor
Other advisors: Professor Nick Martin
-
Doctor Philosophy
Genetic Aetiology of Cognitive and Speech-Related Features in Parkinson's Disease
Principal Advisor
-
Doctor Philosophy
From Genes to Brain Networks: AI Approaches to Understanding the Genetic Foundations of Brain Functionality in Health and Disease
Associate Advisor
-
Doctor Philosophy
Understanding the genetic aetiology of age-related diseases in diverse populations
Associate Advisor
-
Master Philosophy
Application of machine learning techniques on longitudinal fitness tracker data to augment disease risk prediction.
Associate Advisor
Other advisors: Dr Quan Nguyen
-
Doctor Philosophy
Bridging gaps on the genetics of age-related disorder among under-represented populations
Associate Advisor
-
Doctor Philosophy
Genetic architecture of differences in symptomatology and treatment response in major depressive disorder
Associate Advisor
Other advisors: Professor Nick Martin, Honorary Professor Sarah Medland
Completed supervision
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2024
Doctor Philosophy
Elucidating the genetic architecture of neuropsychiatric phenotypes and other complex human traits
Principal Advisor
Other advisors: Professor Nick Martin
-
2022
Doctor Philosophy
Understanding psychiatric disease: From aetiology to outcomes and treatment response
Principal Advisor
Other advisors: Professor Nick Martin
Media
Enquiries
Contact Associate Professor Miguel Rentería directly for media enquiries about:
- Human genetics
- Parkinson's disease
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