
Overview
Background
I am a genetic epidemiologist specialising in the genetics of neurodegenerative diseases, with a particular focus on Parkinson’s disease, chronic pain, and other age-related conditions. I lead a dynamic team of scientists dedicated to understanding how genetic and environmental factors influence neurodegeneration, brain health, and related health outcomes. My research is interdisciplinary, integrating advanced statistical genetics, bioinformatics, and data science to unravel disease mechanisms, improve patient stratification, and identify potential therapeutic targets.
In 2020, I founded the Australian Parkinson’s Genetics Study (APGS), now the largest Parkinson’s cohort in Australia with over 10,000 participants. This landmark study has positioned Australia as a key contributor to global Parkinson’s genetics research. I am also actively involved in the Global Parkinson’s Genetics Program (GP2), where I contribute to large-scale data analysis and work within the underrepresented populations working group to enhance diversity in genetic research worldwide.
Committed to training the next generation of researchers, I have supervised over 16 students, including several PhD candidates who have gone on to successful careers in academia and industry. Two of my recent PhD graduates received the Outstanding Thesis Award, and another received the AIPS Florey Next Generation Award.
I have published consistently in prominent journals, including Nature, Nature Genetics, Nature Communications, BRAIN, Biological Psychiatry, and SLEEP. To date, I have authored over 100 academic articles, which have been widely cited, and I have secured competitive funding from NHMRC, MRFF, The Michael J. Fox Foundation for Parkinson’s Research, Shake It Up Australia Foundation, the US National Institutes of Health, and the Alzheimer’s Association. My work has been recognised with several prestigious awards, including the 2023 Al & Val Rosenstrauss Fellowship from the Rebecca L Cooper Medical Research Foundation, the 2021 Enrico Greppi International Migraine Research Award, and the 2024 Adele Green Emerging Leader Award from QIMR Berghofer Medical Research Institute. I am also a Global Atlantic Fellow for Equity in Brain Health, a program by the University of California San Francisco and Trinity College Dublin, which supports my commitment to promoting brain health equity worldwide.
Availability
- Associate Professor Miguel Rentería is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Bachelor (Honours) of Genomics, Universidad Nacional Autónoma de México (UNAM)
- Doctor of Philosophy of Genetics, The University of Queensland
- Masters (Coursework) of Public Policy, University of Oxford
Works
Search Professor Miguel Rentería’s works on UQ eSpace
2022
Journal Article
Editorial: Data Mining and Statistical Methods for Knowledge Discovery in Diseases Based on Multimodal Omics
Wang, Tao, Rentería, Miguel E. and Peng, Jiajie (2022). Editorial: Data Mining and Statistical Methods for Knowledge Discovery in Diseases Based on Multimodal Omics. Frontiers in Genetics, 13 895796. doi: 10.3389/fgene.2022.895796
2022
Journal Article
NeuroBlu, an electronic health record (EHR) trusted research environment (TRE) to support mental healthcare analytics with real-world data
Patel, Rashmi, Wee, Soon Nan, Ramaswamy, Rajagopalan, Thadani, Simran, Tandi, Jesisca, Garg, Ruchir, Calvanese, Nathan, Valko, Matthew, Rush, A. John, Rentería, Miguel E., Sarkar, Joydeep and Kollins, Scott H. (2022). NeuroBlu, an electronic health record (EHR) trusted research environment (TRE) to support mental healthcare analytics with real-world data. BMJ Open, 12 (4) e057227, 1-11. doi: 10.1136/bmjopen-2021-057227
2022
Journal Article
Genomics-driven screening for causal determinants of suicide attempt
Campos, Adrian I., Garcia-Marin, Luis M., Christensen, Helen, Batterham, Philip J., van Velzen, Laura S., Schmaal, Lianne, Rabinowitz, Jill A., Jahanshad, Neda, Martin, Nicholas G., Cuellar-Partida, Gabriel, Ruderfer, Douglas, Mullins, Niamh, Rentería, Miguel E. and The International Suicide Genetics Consortium (2022). Genomics-driven screening for causal determinants of suicide attempt. Australian and New Zealand Journal of Psychiatry, 57 (3) 00048674221091499, 48674221091499-431. doi: 10.1177/00048674221091499
2022
Journal Article
Positive associations between cannabis and alcohol use polygenic risk scores and phenotypic opioid misuse among African-Americans
Rabinowitz, Jill A., Jin, Jin, Kuo, Sally I-Chun, Campos, Adrian I., Rentería, Miguel E., Huhn, Andrew S., Thrul, Johannes, Reboussin, Beth A., Benke, Kelly, Domingue, Benjamin, Ialongo, Nicholas S., Maher, Brion S., Kertes, Darlene, Troiani, Vanessa and Uhl, George (2022). Positive associations between cannabis and alcohol use polygenic risk scores and phenotypic opioid misuse among African-Americans. PloS One, 17 (4) e0266384, e0266384. doi: 10.1371/journal.pone.0266384
2022
Journal Article
Identifying the Common Genetic Basis of Antidepressant Response
Pain, Oliver, Hodgson, Karen, Trubetskoy, Vassily, Ripke, Stephan, Marshe, Victoria S., Adams, Mark J., Byrne, Enda M., Campos, Adrian I., Carrillo-Roa, Tania, Cattaneo, Annamaria, Als, Thomas D., Souery, Daniel, Dernovsek, Mojca Z., Fabbri, Chiara, Hayward, Caroline, Henigsberg, Neven, Hauser, Joanna, Kennedy, James L., Lenze, Eric J., Lewis, Glyn, Müller, Daniel J., Martin, Nicholas G., Mulsant, Benoit H., Mors, Ole, Perroud, Nader, Porteous, David J., Rentería, Miguel E., Reynolds, Charles F., Rietschel, Marcella ... Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (2022). Identifying the Common Genetic Basis of Antidepressant Response. Biological Psychiatry Global Open Science, 2 (2), 115-126. doi: 10.1016/j.bpsgos.2021.07.008
2022
Journal Article
Shared genetic etiology between cortical brain morphology and tobacco, alcohol, and cannabis use
Rabinowitz, Jill A., Campos, Adrian I., Ong, Jue-Sheng, García-Marín, Luis M., Alcauter, Sarael, Mitchell, Brittany L, Grasby, Katrina L, Cuéllar-Partida, Gabriel, Gillespie, Nathan A, Huhn, Andrew S, Martin, Nicholas G, Thompson, Paul M, Medland, Sarah E, Maher, Brion S and Rentería, Miguel E (2022). Shared genetic etiology between cortical brain morphology and tobacco, alcohol, and cannabis use. Cerebral Cortex, 32 (4), 796-807. doi: 10.1093/cercor/bhab243
2022
Journal Article
Classification of suicidal thoughts and behaviour in children: results from penalised logistic regression analyses in the Adolescent Brain Cognitive Development study
van Velzen, Laura S., Toenders, Yara J., Avila-Parcet, Aina, Dinga, Richard, Rabinowitz, Jill A., Campos, Adrián I., Jahanshad, Neda, Rentería, Miguel E. and Schmaal, Lianne (2022). Classification of suicidal thoughts and behaviour in children: results from penalised logistic regression analyses in the Adolescent Brain Cognitive Development study. The British Journal of Psychiatry, 220 (4), 1-9. doi: 10.1192/bjp.2022.7
2022
Journal Article
Genome-wide association meta-analysis identifies 29 new acne susceptibility loci
Mitchell, Brittany L., Saklatvala, Jake R., Dand, Nick, Hagenbeek, Fiona A., Li, Xin, Min, Josine L., Thomas, Laurent, Bartels, Meike, Jan Hottenga, Jouke, Lupton, Michelle K., Boomsma, Dorret I., Dong, Xianjun, Hveem, Kristian, Løset, Mari, Martin, Nicholas G., Barker, Jonathan N., Han, Jiali, Smith, Catherine H., Rentería, Miguel E. and Simpson, Michael A. (2022). Genome-wide association meta-analysis identifies 29 new acne susceptibility loci. Nature Communications, 13 (1) 702, 702. doi: 10.1038/s41467-022-28252-5
2022
Journal Article
Australian Parkinson’s Genetics Study (APGS): pilot (n=1532)
Bivol, Svetlana, Mellick, George D., Gratten, Jacob, Parker, Richard, Mulcahy, Aoibhe, Mosley, Philip E., Poortvliet, Peter C., Campos, Adrian I., Mitchell, Brittany L., Garcia-Marin, Luis M., Cross, Simone, Ferguson, Mary, Lind, Penelope A., Loesch, Danuta Z., Visscher, Peter M., Medland, Sarah E., Scherzer, Clemens R., Martin, Nicholas G. and Rentería, Miguel E. (2022). Australian Parkinson’s Genetics Study (APGS): pilot (n=1532). BMJ Open, 12 (2) e052032, e052032. doi: 10.1136/bmjopen-2021-052032
2022
Journal Article
Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders, and known risk factors
Mullins, Niamh, Kang, JooEun, Campos, Adrian I., Coleman, Jonathan R I, Edwards, Alexis C., Galfalvy, Hanga, Levey, Daniel F., Lori, Adriana, Shabalin, Andrey, Starnawska, Anna, Su, Mei-Hsin, Watson, Hunna J., Adams, Mark, Awasthi, Swapnil, Gandal, Michael, Hafferty, Jonathan D., Hishimoto, Akitoyo, Kim, Minsoo, Okazaki, Satoshi, Otsuka, Ikuo, Ripke, Stephan, Ware, Erin B., Bergen, Andrew W., Berrettini, Wade H., Bohus, Martin, Brandt, Harry, Chang, Xiao, Chen, Wei J., Chen, Hsi-Chung ... Ruderfer, Douglas M. (2022). Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders, and known risk factors. Biological Psychiatry, 91 (3), 313-327. doi: 10.1016/j.biopsych.2021.05.029
2022
Journal Article
Impact of CYP2C19 metaboliser status on SSRI response: a retrospective study of 9500 participants of the Australian Genetics of Depression Study
Campos, Adrian I., Byrne, Enda M., Mitchell, Brittany L., Wray, Naomi R., Lind, Penelope A., Licinio, Julio, Medland, Sarah E., Martin, Nicholas G., Hickie, Ian B. and Rentería, Miguel E. (2022). Impact of CYP2C19 metaboliser status on SSRI response: a retrospective study of 9500 participants of the Australian Genetics of Depression Study. The Pharmacogenomics Journal, 22 (2), 130-135. doi: 10.1038/s41397-022-00267-7
2022
Journal Article
Is genetic risk for sleep apnea causally linked With glaucoma susceptibility?
Ingold, Nathan, Campos, Adrian I., Han, Xikun, Ong, Jue-Sheng, Gharahkhani, Puya, Mackey, David A., Rentería, Miguel E., Law, Matthew H. and MacGregor, Stuart (2022). Is genetic risk for sleep apnea causally linked With glaucoma susceptibility?. Investigative ophthalmology & visual science, 63 (1) 25, 25. doi: 10.1167/iovs.63.1.25
2022
Journal Article
Systematic Review: microRNAs as Potential Biomarkers in Mild Cognitive Impairment Diagnosis
Ogonowski, Natalia, Salcidua, Stefanny, Leon, Tomas, Chamorro-Veloso, Nayaret, Valls, Cristian, Avalos, Constanza, Bisquertt, Alejandro, Rentería, Miguel E., Orellana, Paulina and Duran-Aniotz, Claudia (2022). Systematic Review: microRNAs as Potential Biomarkers in Mild Cognitive Impairment Diagnosis. Frontiers in Aging Neuroscience, 13 807764, 807764. doi: 10.3389/fnagi.2021.807764
2021
Journal Article
Genetic basis to structural grey matter associations with chronic pain
Farrell, Scott F, Campos, Adrián I, Kho, Pik-Fang, de Zoete, Rutger M J, Sterling, Michele, Rentería, Miguel E, Ngo, Trung Thanh and Cuéllar-Partida, Gabriel (2021). Genetic basis to structural grey matter associations with chronic pain. Brain, 144 (12), 3611-3622. doi: 10.1093/brain/awab334
2021
Journal Article
Phenome-wide analysis highlights putative causal relationships between self-reported migraine and other complex traits
García-Marín, Luis M., Campos, Adrián I., Martin, Nicholas G., Cuéllar-Partida, Gabriel and Rentería, Miguel E. (2021). Phenome-wide analysis highlights putative causal relationships between self-reported migraine and other complex traits. Journal of Headache and Pain, 22 (1) 66, 66. doi: 10.1186/s10194-021-01284-w
2021
Journal Article
Large-scale genetic investigation reveals genetic liability to multiple complex traits influencing a higher risk of ADHD
García-Marín, Luis M., Campos, Adrián I., Cuéllar-Partida, Gabriel, Medland, Sarah E., Kollins, Scott H. and Rentería, Miguel E. (2021). Large-scale genetic investigation reveals genetic liability to multiple complex traits influencing a higher risk of ADHD. Scientific Reports, 11 (1) 22628, 22628. doi: 10.1038/s41598-021-01517-7
2021
Journal Article
Suicidal ideation and planning among Mexican adolescents are associated with depression polygenic risk scores
Martinez‐Levy, Gabriela A., Campos, Adrian I., Rabinowitz, Jill A., García‐Marín, Luis M., Benjet, Corina, Méndez, Enrique, Rentería, Miguel E. and Cruz‐Fuentes, Carlos S. (2021). Suicidal ideation and planning among Mexican adolescents are associated with depression polygenic risk scores. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 186 (8) ajmg.b.32864, 476-484. doi: 10.1002/ajmg.b.32864
2021
Journal Article
Understanding the effect of smoking and drinking behavior on Parkinson's disease risk: a Mendelian randomization study
Domínguez-Baleón, Carmen, Ong, Jue-Sheng, Scherzer, Clemens R., Rentería, Miguel E. and Dong, Xianjun (2021). Understanding the effect of smoking and drinking behavior on Parkinson's disease risk: a Mendelian randomization study. Scientific Reports, 11 (1) 13980. doi: 10.1038/s41598-021-93105-y
2021
Journal Article
Understanding genetic risk factors for common side effects of antidepressant medications
Campos, Adrian I., Mulcahy, Aoibhe, Thorp, Jackson G., Wray, Naomi R., Byrne, Enda M., Lind, Penelope A., Medland, Sarah E., Martin, Nicholas G., Hickie, Ian B. and Rentería, Miguel E. (2021). Understanding genetic risk factors for common side effects of antidepressant medications. Communications Medicine, 1 (1) 45, 1-10. doi: 10.1038/s43856-021-00046-8
2021
Journal Article
Identifying complex lncRNA/Pseudogene–miRNA–mRNA crosstalk in hormone-dependent cancers
Jayarathna, Dulari K., Rentería, Miguel E., Sauret, Emilie, Batra, Jyotsna and Gandhi, Neha S. (2021). Identifying complex lncRNA/Pseudogene–miRNA–mRNA crosstalk in hormone-dependent cancers. Biology, 10 (10) 1014, 1014. doi: 10.3390/biology10101014
Supervision
Availability
- Associate Professor Miguel Rentería is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
Genetic Aetiology of Cognitive and Speech-Related Features in Parkinson's Disease
Principal Advisor
-
Doctor Philosophy
Monogenic Parkinson's disease among individuals from underrepresented backgrounds in Australia and Mexico
Principal Advisor
-
Doctor Philosophy
From Genes to Brain Networks: AI Approaches to Understanding the Genetic Foundations of Brain Functionality in Health and Disease
Associate Advisor
-
Doctor Philosophy
Understanding the genetic aetiology of age-related diseases in diverse populations
Associate Advisor
-
Doctor Philosophy
Genetic architecture of differences in symptomatology and treatment response in major depressive disorder
Associate Advisor
Other advisors: Professor Nick Martin, Honorary Professor Sarah Medland
-
Master Philosophy
Application of machine learning techniques on longitudinal fitness tracker data to augment disease risk prediction.
Associate Advisor
Other advisors: Dr Quan Nguyen
-
Doctor Philosophy
Bridging gaps on the genetics of age-related disorder among under-represented populations
Associate Advisor
Completed supervision
-
2024
Doctor Philosophy
Elucidating the genetic architecture of neuropsychiatric phenotypes and other complex human traits
Principal Advisor
Other advisors: Professor Nick Martin
-
2022
Doctor Philosophy
Understanding psychiatric disease: From aetiology to outcomes and treatment response
Principal Advisor
Other advisors: Professor Nick Martin
Media
Enquiries
Contact Associate Professor Miguel Rentería directly for media enquiries about:
- Human genetics
- Parkinson's disease
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