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Dr Marina Naval Sanchez
Dr

Marina Naval Sanchez

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Overview

Background

Dr. Marina Naval-Sanchez is a NHMRC Research Fellow at the Institute for Molecular Bioscience at The University of Queensland (Australia). She pursued postdoctoral studies in 2019-2024 in the Institute for Molecular Bioscience, The University of Queensland (Australia) and as an Office Chief Executive (OCE) Fellow in 2015-2019 at the Commonwealth Scientific and Industrial Research Organisation (CSIRO) (Australia). She received her PhD in Molecular Biosciences in 2014 from KULeuven (Belgium). She received her MSc in Applied Bioinformatics in 2009 from Cranfield University (UK) and MSc in Agriculture Engineering in 2008 from the Universitat de Lleida (Spain).

Marina’s research program applies state-of-the-art bioinformatic, machine learning, and genetic and genomic tools to unearth the master regulators and enhancer grammar governing development and ageing across species (mouse and human) and to decipher the genomic (regulatory) impact of evolution, domestication and human selection in farm species (sheep, cattle, salmon). Her research outcomes have been published in high-impact journals such as Cell Metabolism, Nature Communications, Genome Biology, Nucleic Acids Research, Genome Research and Molecular Biology and Evolution.

Her research efforts have been supported by domestic and international fellowships and grants, including the Australian National Health and Medical Research Council (NHMRC, EL1 2024 Recipient), Advance Queensland, UQ Innovation Connections, CSIRO Scientific Investment Projects, CSIRO OCE Fellowships, and Flanders Wetesnchappelijk Onderzoek (FWO) PhD Fellowship.

Availability

Dr Marina Naval Sanchez is:
Available for supervision

Qualifications

  • Doctor of Philosophy, Catholic University of Leuven

Works

Search Professor Marina Naval Sanchez’s works on UQ eSpace

35 works between 2008 and 2024

21 - 35 of 35 works

2018

Journal Article

Amniotic ectoderm expansion in mouse occurs via distinct modes and requires SMAD5-mediated signalling

Dobreva, Mariya P., Escalona, Vanesa Abon, Lawson, Kirstie A., Sanchez, Marina N., Ponomarev, Ljuba C., Pereira, Paulo N. G., Stryjewska, Agata, Criem, Nathan, Huylebroeck, Danny, Lopes, Susana M. Chuva de Sousa, Aerts, Stein and Zwijsen, An (2018). Amniotic ectoderm expansion in mouse occurs via distinct modes and requires SMAD5-mediated signalling. Development, 145 (13) dev157222, dev157222. doi: 10.1242/dev.157222

Amniotic ectoderm expansion in mouse occurs via distinct modes and requires SMAD5-mediated signalling

2018

Journal Article

A haplotype information theory method reveals genes of evolutionary interest in European vs. Asian pigs

Hudson, Nicholas J., Naval-Sánchez, Marina, Porto-Neto, Laercio, Pérez-Enciso, Miguel and Reverter, Antonio (2018). A haplotype information theory method reveals genes of evolutionary interest in European vs. Asian pigs. Journal of Animal Science, 96 (8), 3064-3069. doi: 10.1093/jas/sky225

A haplotype information theory method reveals genes of evolutionary interest in European vs. Asian pigs

2018

Journal Article

Evolution of sex determination loci in Atlantic salmon

Kijas, James, McWilliam, Sean, Sanchez, Marina Naval, Kube, Peter, King, Harry, Evans, Bradley, Nome, Torfinn, Lien, Sigbjorn and Verbyla, Klara (2018). Evolution of sex determination loci in Atlantic salmon. Scientific Reports, 8 (1) 5664, 5664. doi: 10.1038/s41598-018-23984-1

Evolution of sex determination loci in Atlantic salmon

2018

Journal Article

Mammalian genomic regulatory regions predicted by utilizing human genomics, transcriptomics, and epigenetics data

Nguyen, Quan H., Tellam, Ross L., Naval-Sanchez, Marina, Porto-Neto, Laercio R., Barendse, William, Reverter, Antonio, Hayes, Benjamin, Kijas, James and Dalrymple, Brian P. (2018). Mammalian genomic regulatory regions predicted by utilizing human genomics, transcriptomics, and epigenetics data. Gigascience, 7 (3), 1-17. doi: 10.1093/gigascience/gix136

Mammalian genomic regulatory regions predicted by utilizing human genomics, transcriptomics, and epigenetics data

2018

Journal Article

Sheep genome functional annotation reveals proximal regulatory elements contributed to the evolution of modern breeds

Naval-Sanchez, Marina, Nguyen, Quan, McWilliam, Sean, Porto-Neto, Laercio R., Tellam, Ross, Vuocolo, Tony, Reverter, Antonio, Perez-Enciso, Miguel, Brauning, Rudiger, Clarke, Shannon, McCulloch, Alan, Zamani, Wahid, Naderi, Saeid, Rezaei, Hamid Reza, Pompanon, Francois, Taberlet, Pierre, Worley, Kim C., Gibbs, Richard A., Muzny, Donna M., Jhangiani, Shalini N., Cockett, Noelle, Daetwyler, Hans and Kijas, James (2018). Sheep genome functional annotation reveals proximal regulatory elements contributed to the evolution of modern breeds. Nature Communications, 9 (1) 859. doi: 10.1038/s41467-017-02809-1

Sheep genome functional annotation reveals proximal regulatory elements contributed to the evolution of modern breeds

2017

Journal Article

Nuclear receptors connect progenitor transcription factors to cell cycle control

Neto, Marta, Naval-Sanchez, Marina, Potier, Delphine, Pereira, Paulo S., Geerts, Dirk, Aerts, Stein and Casares, Fernando (2017). Nuclear receptors connect progenitor transcription factors to cell cycle control. Scientific Reports, 7 (1) 4845, 4845. doi: 10.1038/s41598-017-04936-7

Nuclear receptors connect progenitor transcription factors to cell cycle control

2016

Journal Article

Genome-wide association reveals the locus responsible for four-horned ruminant

Kijas, James W., Hadfield, Tracy, Naval Sanchez, Marina and Cockett, Noelle (2016). Genome-wide association reveals the locus responsible for four-horned ruminant. Animal Genetics, 47 (2), 258-62. doi: 10.1111/age.12409

Genome-wide association reveals the locus responsible for four-horned ruminant

2015

Journal Article

Identification of lineage-specific Cis-regulatory modules associated with variation in transcription factor binding and chromatin activity using Ornstein-Uhlenbeck models

Naval-Sanchez, Marina, Potier, Delphine, Hulselmans, Gert, Christiaens, Valerie and Aerts, Stein (2015). Identification of lineage-specific Cis-regulatory modules associated with variation in transcription factor binding and chromatin activity using Ornstein-Uhlenbeck models. Molecular Biology and Evolution, 32 (9), 2441-2455. doi: 10.1093/molbev/msv107

Identification of lineage-specific Cis-regulatory modules associated with variation in transcription factor binding and chromatin activity using Ornstein-Uhlenbeck models

2014

Journal Article

Mapping gene regulatory networks in Drosophila eye development by large-scale transcriptome perturbations and motif inference

Potier, Delphine, Davie, Kristofer, Hulselmans, Gert, Sanchez, Marina Naval, Haagen, Lotte, Van Anh Huynh-Thu,, Koldere, Duygu, Celik, Arzu, Geurts, Pierre, Christiaens, Valerie and Aerts, Stein (2014). Mapping gene regulatory networks in Drosophila eye development by large-scale transcriptome perturbations and motif inference. Cell Reports, 9 (6), 2290-2303. doi: 10.1016/j.celrep.2014.11.038

Mapping gene regulatory networks in Drosophila eye development by large-scale transcriptome perturbations and motif inference

2014

Journal Article

iRegulon: From a gene list to a gene regulatory network using large motif and track collections

Janky, Rekin's, Verfaillie, Annelien, Imrichova, Hana, Van de Sande, Bram, Standaert, Laura, Christiaens, Valerie, Hulselmans, Gert, Herten, Koen, Sanchez, Marina Naval, Potier, Delphine, Svetlichnyy, Dmitry, Atak, Zeynep Kalender, Fiers, Mark, Marine, Jean-Christophe and Aerts, Stein (2014). iRegulon: From a gene list to a gene regulatory network using large motif and track collections. PLOS Computational Biology, 10 (7) e1003731, e1003731. doi: 10.1371/journal.pcbi.1003731

iRegulon: From a gene list to a gene regulatory network using large motif and track collections

2013

Journal Article

TDP-43 loss-of-function causes neuronal loss due to defective steroid receptor-mediated gene program switching in Drosophila

Broeck, Lies Vanden, Naval-Sanchez, Marina, Adachi, Yoshitsugu, Diaper, Danielle, Dourlen, Pierre, Chapuis, Julien, Kleinberger, Gernot, Gistelinck, Marc, Van Broeckhoven, Christine, Lambert, Jean-Charles, Hirth, Frank, Aerts, Stein, Callaerts, Patrick and Dermaut, Bart (2013). TDP-43 loss-of-function causes neuronal loss due to defective steroid receptor-mediated gene program switching in Drosophila. Cell Reports, 3 (1), 160-172. doi: 10.1016/j.celrep.2012.12.014

TDP-43 loss-of-function causes neuronal loss due to defective steroid receptor-mediated gene program switching in Drosophila

2013

Journal Article

Comparative motif discovery combined with comparative transcriptomics yields accurate targetome and enhancer predictions

Naval-Sanchez, Marina, Potier, Delphine, Haagen, Lotte, Sanchez, Maximo, Munck, Sebastian, Van de Sande, Bram, Casares, Fernando, Christiaens, Valerie and Aerts, Stein (2013). Comparative motif discovery combined with comparative transcriptomics yields accurate targetome and enhancer predictions. Genome Research, 23 (1), 74-88. doi: 10.1101/gr.140426.112

Comparative motif discovery combined with comparative transcriptomics yields accurate targetome and enhancer predictions

2012

Book Chapter

Using cisTargetX to predict transcriptional targets and networks in Drosophila

Potier, Delphine, Atak, Zeynep Kalender, Sanchez, Marina Naval, Herrmann, Carl and Aerts, Stein (2012). Using cisTargetX to predict transcriptional targets and networks in Drosophila. Gene regulatory networks: methods and protocols. (pp. 291-314) edited by Bart Deplancke and Nele Gheldof. New York, NY, United States: Humana Press. doi: 10.1007/978-1-61779-292-2_18

Using cisTargetX to predict transcriptional targets and networks in Drosophila

2010

Journal Article

Robust target gene discovery through transcriptome perturbations and genome-wide enhancer predictions in drosophila uncovers a regulatory basis for sensory specification

Aerts, Stein, Quan, Xiao-Jiang, Claeys, Annelies, Sanchez, Marina Naval, Tate, Phillip, Yan, Jiekun and Hassan, Bassem A. (2010). Robust target gene discovery through transcriptome perturbations and genome-wide enhancer predictions in drosophila uncovers a regulatory basis for sensory specification. PLoS Biology, 8 (7) e1000435, e1000435. doi: 10.1371/journal.pbio.1000435

Robust target gene discovery through transcriptome perturbations and genome-wide enhancer predictions in drosophila uncovers a regulatory basis for sensory specification

2008

Journal Article

Measurement of free zinc concentration in wine with AGNES

Companys, Encarnacio, Naval-Sanchez, Marina, Martinez-Micaelo, Neus, Puy, Jaume and Galceran, Josep (2008). Measurement of free zinc concentration in wine with AGNES. Journal of Agricultural and Food Chemistry, 56 (18), 8296-8302. doi: 10.1021/jf8013475

Measurement of free zinc concentration in wine with AGNES

Funding

Current funding

  • 2025 - 2029
    Deciphering the gene regulatory code of ageing to set the stage for therapeutic intervention
    NHMRC Investigator Grants
    Open grant

Past funding

  • 2021 - 2022
    Dr Marina Naval Sanchez - AQ WRAP
    Advance Queensland Women's Research Assistance Program
    Open grant

Supervision

Availability

Dr Marina Naval Sanchez is:
Available for supervision

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Available projects

Supervision history

Current supervision

  • Doctor Philosophy

    Development of a multimodal single-cell assay reveals somatic NFI transcription factors as dose-dependent pluripotency mediators

    Associate Advisor

    Other advisors: Professor Matt Sweet, Dr Christian Nefzger

  • Doctor Philosophy

    Deciphering the age-altered transcription factor network and its control over regenerative potential

    Associate Advisor

    Other advisors: Dr Quan Nguyen, Dr Christian Nefzger

  • Doctor Philosophy

    Leveraging integrative multiomic data to enable controlled cell state transition

    Associate Advisor

    Other advisors: Professor Matt Sweet, Dr Christian Nefzger

  • Doctor Philosophy

    Leveraging integrative multiomic data to enable controlled cell state transition

    Associate Advisor

    Other advisors: Professor Matt Sweet, Dr Christian Nefzger

  • Doctor Philosophy

    Network reinforcement to improve the function of aged cells

    Associate Advisor

    Other advisors: Dr Christian Nefzger

Media

Enquiries

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