
Overview
Background
Dr. Marina Naval-Sanchez is a NHMRC Research Fellow at the Institute for Molecular Bioscience at The University of Queensland (Australia). She pursued postdoctoral studies in 2019-2024 in the Institute for Molecular Bioscience, The University of Queensland (Australia) and as an Office Chief Executive (OCE) Fellow in 2015-2019 at the Commonwealth Scientific and Industrial Research Organisation (CSIRO) (Australia). She received her PhD in Molecular Biosciences in 2014 from KULeuven (Belgium). She received her MSc in Applied Bioinformatics in 2009 from Cranfield University (UK) and MSc in Agriculture Engineering in 2008 from the Universitat de Lleida (Spain).
Marina’s research program applies state-of-the-art bioinformatic, machine learning, and genetic and genomic tools to unearth the master regulators and enhancer grammar governing development and ageing across species (mouse and human) and to decipher the genomic (regulatory) impact of evolution, domestication and human selection in farm species (sheep, cattle, salmon). Her research outcomes have been published in high-impact journals such as Cell Metabolism, Nature Communications, Genome Biology, Nucleic Acids Research, Genome Research and Molecular Biology and Evolution.
Her research efforts have been supported by domestic and international fellowships and grants, including the Australian National Health and Medical Research Council (NHMRC, EL1 2024 Recipient), Advance Queensland, UQ Innovation Connections, CSIRO Scientific Investment Projects, CSIRO OCE Fellowships, and Flanders Wetesnchappelijk Onderzoek (FWO) PhD Fellowship.
Availability
- Dr Marina Naval Sanchez is:
- Available for supervision
Qualifications
- Doctor of Philosophy, Catholic University of Leuven
Works
Search Professor Marina Naval Sanchez’s works on UQ eSpace
2018
Journal Article
Amniotic ectoderm expansion in mouse occurs via distinct modes and requires SMAD5-mediated signalling
Dobreva, Mariya P., Escalona, Vanesa Abon, Lawson, Kirstie A., Sanchez, Marina N., Ponomarev, Ljuba C., Pereira, Paulo N. G., Stryjewska, Agata, Criem, Nathan, Huylebroeck, Danny, Lopes, Susana M. Chuva de Sousa, Aerts, Stein and Zwijsen, An (2018). Amniotic ectoderm expansion in mouse occurs via distinct modes and requires SMAD5-mediated signalling. Development, 145 (13) dev157222, dev157222. doi: 10.1242/dev.157222
2018
Journal Article
A haplotype information theory method reveals genes of evolutionary interest in European vs. Asian pigs
Hudson, Nicholas J., Naval-Sánchez, Marina, Porto-Neto, Laercio, Pérez-Enciso, Miguel and Reverter, Antonio (2018). A haplotype information theory method reveals genes of evolutionary interest in European vs. Asian pigs. Journal of Animal Science, 96 (8), 3064-3069. doi: 10.1093/jas/sky225
2018
Journal Article
Evolution of sex determination loci in Atlantic salmon
Kijas, James, McWilliam, Sean, Sanchez, Marina Naval, Kube, Peter, King, Harry, Evans, Bradley, Nome, Torfinn, Lien, Sigbjorn and Verbyla, Klara (2018). Evolution of sex determination loci in Atlantic salmon. Scientific Reports, 8 (1) 5664, 5664. doi: 10.1038/s41598-018-23984-1
2018
Journal Article
Mammalian genomic regulatory regions predicted by utilizing human genomics, transcriptomics, and epigenetics data
Nguyen, Quan H., Tellam, Ross L., Naval-Sanchez, Marina, Porto-Neto, Laercio R., Barendse, William, Reverter, Antonio, Hayes, Benjamin, Kijas, James and Dalrymple, Brian P. (2018). Mammalian genomic regulatory regions predicted by utilizing human genomics, transcriptomics, and epigenetics data. Gigascience, 7 (3), 1-17. doi: 10.1093/gigascience/gix136
2018
Journal Article
Sheep genome functional annotation reveals proximal regulatory elements contributed to the evolution of modern breeds
Naval-Sanchez, Marina, Nguyen, Quan, McWilliam, Sean, Porto-Neto, Laercio R., Tellam, Ross, Vuocolo, Tony, Reverter, Antonio, Perez-Enciso, Miguel, Brauning, Rudiger, Clarke, Shannon, McCulloch, Alan, Zamani, Wahid, Naderi, Saeid, Rezaei, Hamid Reza, Pompanon, Francois, Taberlet, Pierre, Worley, Kim C., Gibbs, Richard A., Muzny, Donna M., Jhangiani, Shalini N., Cockett, Noelle, Daetwyler, Hans and Kijas, James (2018). Sheep genome functional annotation reveals proximal regulatory elements contributed to the evolution of modern breeds. Nature Communications, 9 (1) 859. doi: 10.1038/s41467-017-02809-1
2017
Journal Article
Nuclear receptors connect progenitor transcription factors to cell cycle control
Neto, Marta, Naval-Sanchez, Marina, Potier, Delphine, Pereira, Paulo S., Geerts, Dirk, Aerts, Stein and Casares, Fernando (2017). Nuclear receptors connect progenitor transcription factors to cell cycle control. Scientific Reports, 7 (1) 4845, 4845. doi: 10.1038/s41598-017-04936-7
2016
Journal Article
Genome-wide association reveals the locus responsible for four-horned ruminant
Kijas, James W., Hadfield, Tracy, Naval Sanchez, Marina and Cockett, Noelle (2016). Genome-wide association reveals the locus responsible for four-horned ruminant. Animal Genetics, 47 (2), 258-62. doi: 10.1111/age.12409
2015
Journal Article
Identification of lineage-specific Cis-regulatory modules associated with variation in transcription factor binding and chromatin activity using Ornstein-Uhlenbeck models
Naval-Sanchez, Marina, Potier, Delphine, Hulselmans, Gert, Christiaens, Valerie and Aerts, Stein (2015). Identification of lineage-specific Cis-regulatory modules associated with variation in transcription factor binding and chromatin activity using Ornstein-Uhlenbeck models. Molecular Biology and Evolution, 32 (9), 2441-2455. doi: 10.1093/molbev/msv107
2014
Journal Article
Mapping gene regulatory networks in Drosophila eye development by large-scale transcriptome perturbations and motif inference
Potier, Delphine, Davie, Kristofer, Hulselmans, Gert, Sanchez, Marina Naval, Haagen, Lotte, Van Anh Huynh-Thu,, Koldere, Duygu, Celik, Arzu, Geurts, Pierre, Christiaens, Valerie and Aerts, Stein (2014). Mapping gene regulatory networks in Drosophila eye development by large-scale transcriptome perturbations and motif inference. Cell Reports, 9 (6), 2290-2303. doi: 10.1016/j.celrep.2014.11.038
2014
Journal Article
iRegulon: From a gene list to a gene regulatory network using large motif and track collections
Janky, Rekin's, Verfaillie, Annelien, Imrichova, Hana, Van de Sande, Bram, Standaert, Laura, Christiaens, Valerie, Hulselmans, Gert, Herten, Koen, Sanchez, Marina Naval, Potier, Delphine, Svetlichnyy, Dmitry, Atak, Zeynep Kalender, Fiers, Mark, Marine, Jean-Christophe and Aerts, Stein (2014). iRegulon: From a gene list to a gene regulatory network using large motif and track collections. PLOS Computational Biology, 10 (7) e1003731, e1003731. doi: 10.1371/journal.pcbi.1003731
2013
Journal Article
TDP-43 loss-of-function causes neuronal loss due to defective steroid receptor-mediated gene program switching in Drosophila
Broeck, Lies Vanden, Naval-Sanchez, Marina, Adachi, Yoshitsugu, Diaper, Danielle, Dourlen, Pierre, Chapuis, Julien, Kleinberger, Gernot, Gistelinck, Marc, Van Broeckhoven, Christine, Lambert, Jean-Charles, Hirth, Frank, Aerts, Stein, Callaerts, Patrick and Dermaut, Bart (2013). TDP-43 loss-of-function causes neuronal loss due to defective steroid receptor-mediated gene program switching in Drosophila. Cell Reports, 3 (1), 160-172. doi: 10.1016/j.celrep.2012.12.014
2013
Journal Article
Comparative motif discovery combined with comparative transcriptomics yields accurate targetome and enhancer predictions
Naval-Sanchez, Marina, Potier, Delphine, Haagen, Lotte, Sanchez, Maximo, Munck, Sebastian, Van de Sande, Bram, Casares, Fernando, Christiaens, Valerie and Aerts, Stein (2013). Comparative motif discovery combined with comparative transcriptomics yields accurate targetome and enhancer predictions. Genome Research, 23 (1), 74-88. doi: 10.1101/gr.140426.112
2012
Book Chapter
Using cisTargetX to predict transcriptional targets and networks in Drosophila
Potier, Delphine, Atak, Zeynep Kalender, Sanchez, Marina Naval, Herrmann, Carl and Aerts, Stein (2012). Using cisTargetX to predict transcriptional targets and networks in Drosophila. Gene regulatory networks: methods and protocols. (pp. 291-314) edited by Bart Deplancke and Nele Gheldof. New York, NY, United States: Humana Press. doi: 10.1007/978-1-61779-292-2_18
2010
Journal Article
Robust target gene discovery through transcriptome perturbations and genome-wide enhancer predictions in drosophila uncovers a regulatory basis for sensory specification
Aerts, Stein, Quan, Xiao-Jiang, Claeys, Annelies, Sanchez, Marina Naval, Tate, Phillip, Yan, Jiekun and Hassan, Bassem A. (2010). Robust target gene discovery through transcriptome perturbations and genome-wide enhancer predictions in drosophila uncovers a regulatory basis for sensory specification. PLoS Biology, 8 (7) e1000435, e1000435. doi: 10.1371/journal.pbio.1000435
2008
Journal Article
Measurement of free zinc concentration in wine with AGNES
Companys, Encarnacio, Naval-Sanchez, Marina, Martinez-Micaelo, Neus, Puy, Jaume and Galceran, Josep (2008). Measurement of free zinc concentration in wine with AGNES. Journal of Agricultural and Food Chemistry, 56 (18), 8296-8302. doi: 10.1021/jf8013475
Supervision
Availability
- Dr Marina Naval Sanchez is:
- Available for supervision
Before you email them, read our advice on how to contact a supervisor.
Available projects
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Deciphering the gene regulatory code of ageing to set the stage for therapeutic interventions
Decipher the gene regulatory code and epigenetic mechanisms governing developmental processes and aging, and their links to disease.
Supervision history
Current supervision
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Doctor Philosophy
Development of a multimodal single-cell assay reveals somatic NFI transcription factors as dose-dependent pluripotency mediators
Associate Advisor
Other advisors: Professor Matt Sweet, Dr Christian Nefzger
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Doctor Philosophy
Deciphering the age-altered transcription factor network and its control over regenerative potential
Associate Advisor
Other advisors: Dr Quan Nguyen, Dr Christian Nefzger
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Doctor Philosophy
Leveraging integrative multiomic data to enable controlled cell state transition
Associate Advisor
Other advisors: Professor Matt Sweet, Dr Christian Nefzger
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Doctor Philosophy
Leveraging integrative multiomic data to enable controlled cell state transition
Associate Advisor
Other advisors: Professor Matt Sweet, Dr Christian Nefzger
-
Doctor Philosophy
Network reinforcement to improve the function of aged cells
Associate Advisor
Other advisors: Dr Christian Nefzger
Media
Enquiries
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