2018 Journal Article Confinement of therapeutic enzymes in selectively permeable polymer vesicles by Polymerization-Induced Self-Assembly (PISA) reduces antibody binding and proteolytic susceptibilityBlackman, Lewis D., Varlas, Spyridon, Arno, Maria C., Houston, Zachary H., Fletcher, Nicholas L., Thurecht, Kristofer J., Hasan, Muhammad, Gibson, Matthew I. and O’Reilly, Rachel K. (2018). Confinement of therapeutic enzymes in selectively permeable polymer vesicles by Polymerization-Induced Self-Assembly (PISA) reduces antibody binding and proteolytic susceptibility. ACS Central Science, 4 (6), 718-723. doi: 10.1021/acscentsci.8b00168 |
2018 Journal Article Towards clinical translation of ligand-functionalized liposomes in targeted cancer therapy: challenges and opportunitiesBelfiore, Lisa, Saunders, Darren N., Ranson, Marie, Thurecht, Kristofer J., Storm, Gert and Vine, Kara L. (2018). Towards clinical translation of ligand-functionalized liposomes in targeted cancer therapy: challenges and opportunities. Journal of Controlled Release, 277, 1-13. doi: 10.1016/j.jconrel.2018.02.040 |
2018 Journal Article Modified organosilica core-shell nanoparticles for stable pH sensing in biological solutionsRobinson, Kye J., Huynh, Gabriel T., Kouskousis, Betty P., Fletcher, Nicholas L., Houston, Zachary H., Thurecht, Kristofer J. and Corrie, Simon R. (2018). Modified organosilica core-shell nanoparticles for stable pH sensing in biological solutions. ACS Sensors, 3 (5), 967-975. doi: 10.1021/acssensors.8b00034 |
2018 Journal Article Enhanced delivery of siRNA to triple negative breast cancer cells in vitro and in vivo through functionalizing lipid-coated calcium phosphate nanoparticles with dual target ligandsTang, Jie, Howard, Christopher B., Mahler, Stephen M., Thurecht, Kristofer J., Huang, Leaf and Xu, Zhi Ping (2018). Enhanced delivery of siRNA to triple negative breast cancer cells in vitro and in vivo through functionalizing lipid-coated calcium phosphate nanoparticles with dual target ligands. Nanoscale, 10 (9), 4258-4266. doi: 10.1039/c7nr08644j |
2018 Journal Article Bispecific antibody-functionalized upconversion nanoprobeHe, Hao, Howard, Christopher B., Chen, Yinghui, Wen, Shihui, Lin, Gungun, Zhou, Jiajia, Thurecht, Kristofer J. and Jin, Dayong (2018). Bispecific antibody-functionalized upconversion nanoprobe. Analytical Chemistry, 90 (5), 3024-3029. doi: 10.1021/acs.analchem.7b05341 |
2018 Journal Article Designed multifunctional polymeric nanomedicines: long-term biodistribution and tumour accumulation of aptamer-targeted nanomaterialsFletcher, N. L., Houston, Z. H., Simpson, J. D., Veedu, R. N. and Thurecht, K. J. (2018). Designed multifunctional polymeric nanomedicines: long-term biodistribution and tumour accumulation of aptamer-targeted nanomaterials. Chemical Communications, 54 (82), 11538-11541. doi: 10.1039/c8cc05831h |
2018 Journal Article Recent advances in the generation of antibody-nanomaterial conjugatesSivaram, Amal J, Wardiana, Andri, Howard, Christopher B, Mahler, Stephen M and Thurecht, Kristofer J (2018). Recent advances in the generation of antibody-nanomaterial conjugates. Advanced Healthcare Materials, 7 (1) 1700607. doi: 10.1002/adhm.201700607 |
2017 Journal Article Effects of Surface Charge of Hyperbranched Polymers on Cytotoxicity, Dynamic Cellular Uptake and Localization, Hemotoxicity, and Pharmacokinetics in MiceChen, Liyu, Simpson, Joshua D, Fuchs, Adrian V, Rolfe, Barbara E and Thurecht, Kristofer J (2017). Effects of Surface Charge of Hyperbranched Polymers on Cytotoxicity, Dynamic Cellular Uptake and Localization, Hemotoxicity, and Pharmacokinetics in Mice. Molecular pharmaceutics, 14 (12), 4485-4497. doi: 10.1021/acs.molpharmaceut.7b00611 |
2017 Journal Article Gold Nanocluster-Mediated Cellular Death under Electromagnetic RadiationCifuentes-Rius, Anna, Ivask, Angela, Das, Shreya, Penya-Auladell, Nuria, Fabregas, Laura, Fletcher, Nicholas L., Houston, Zachary H., Thurecht, Kristofer J. and Voelcker, Nicolas H. (2017). Gold Nanocluster-Mediated Cellular Death under Electromagnetic Radiation. Acs Applied Materials & Interfaces, 9 (47), 41159-41167. doi: 10.1021/acsami.7b13100 |
2017 Journal Article Localised delivery of doxorubicin to prostate cancer cells through a PSMA-targeted hyperbranched polymer theranosticPearce, Amanda K., Simpson, Joshua D., Fletcher, Nicholas L., Houston, Zachary H., Fuchs, Adrian V., Russell, Pamela J., Whittaker, Andrew K. and Thurecht, Kristofer J. (2017). Localised delivery of doxorubicin to prostate cancer cells through a PSMA-targeted hyperbranched polymer theranostic. Biomaterials, 141, 330-339. doi: 10.1016/j.biomaterials.2017.07.004 |
2017 Journal Article Bridging Bio-Nano Science and Cancer NanomedicineBjörnmalm, Mattias, Thurecht, Kristofer J., Michael, Michael, Scott, Andrew M. and Caruso, Frank (2017). Bridging Bio-Nano Science and Cancer Nanomedicine. Acs Nano, 11 (10), 9594-9613. doi: 10.1021/acsnano.7b04855 |
2017 Journal Article Using peptide aptamer targeted polymers as a model nanomedicine for investigating drug distribution in cancer nanotheranosticsZhao, Yongmei, Houston, Zachary H., Simpson, Joshua D., Chen, Liyu, Fletcher, Nicholas L., Fuchs, Adrian V., Blakey, Idriss and Thurecht, Kristofer J. (2017). Using peptide aptamer targeted polymers as a model nanomedicine for investigating drug distribution in cancer nanotheranostics. Molecular Pharmaceutics, 14 (10), 3539-3549. doi: 10.1021/acs.molpharmaceut.7b00560 |
2017 Journal Article Switchable 19F MRI polymer theranostics: towards in situ quantifiable drug releaseFuchs, A. V., Bapat, A. P., Cowin, G. J. and Thurecht, K. J. (2017). Switchable 19F MRI polymer theranostics: towards in situ quantifiable drug release. Polymer Chemistry, 8 (34), 5157-5166. doi: 10.1039/c7py00345e |
2017 Journal Article Charge has a marked influence on hyperbranched polymer nanoparticle association in whole human bloodGlass, Joshua J., Chen, Liyu, Alcantara, Sheilajen, Crampin, Edmund J., Thurecht, Kristofer J., De Rose, Robert and Kent, Stephen J. (2017). Charge has a marked influence on hyperbranched polymer nanoparticle association in whole human blood. ACS Macro Letters, 6 (6), 586-592. doi: 10.1021/acsmacrolett.7b00229 |
2017 Journal Article Synthesis and post-polymerisation ligations of PEG-based hyperbranched polymers for RNA conjugation via reversible disulfide linkageArdana, Aditya, Whittaker, Andrew K. and Thurecht, Kristofer J. (2017). Synthesis and post-polymerisation ligations of PEG-based hyperbranched polymers for RNA conjugation via reversible disulfide linkage. Macromolecular Research, 25 (6), 599-614. doi: 10.1007/s13233-017-5111-z |
2017 Journal Article In vivo fate of carbon nanotubes with different physicochemical properties for gene delivery applicationsCifuentes-Rius, Anna, Boase, Nathan R. B., Font, Ines, Coronas, Nuria, Ramos-Perez, Victor, Thurecht, Kristofer J. and Borros, Salvador (2017). In vivo fate of carbon nanotubes with different physicochemical properties for gene delivery applications. ACS Applied Materials and Interfaces, 9 (13), 11461-11471. doi: 10.1021/acsami.7b00677 |
2017 Journal Article Stability of trithiocarbonate RAFT agents containing both a cyano and a carboxylic acid functional groupFuchs, Adrian V. and Thurecht, Kristofer J. (2017). Stability of trithiocarbonate RAFT agents containing both a cyano and a carboxylic acid functional group. ACS Macro Letters, 6 (3), 287-291. doi: 10.1021/acsmacrolett.7b00100 |
2016 Journal Article Nano-bio interactions: guiding the development of nanoparticle therapeutics, diagnostics, and imaging agentsCorrie, Simon R. and Thurecht, Kristofer J. (2016). Nano-bio interactions: guiding the development of nanoparticle therapeutics, diagnostics, and imaging agents. Pharmaceutical Research, 33 (10), 2311-2313. doi: 10.1007/s11095-016-2009-y |
2016 Journal Article Preclinical imaging of siRNA deliveryFletcher, Nicholas, Ardana, Aditya and Thurecht, Kristofer J. (2016). Preclinical imaging of siRNA delivery. Australian Journal of Chemistry, 69 (10), 1073-1077. doi: 10.1071/CH16079 |
2016 Journal Article Nanoparticle-based medicines: a review of FDA-approved materials and clinical trials to dateBobo, Daniel, Robinson, Kye J., Islam, Jiaul, Thurecht, Kristofer J. and Corrie, Simon R. (2016). Nanoparticle-based medicines: a review of FDA-approved materials and clinical trials to date. Pharmaceutical Research, 33 (10), 2373-2387. doi: 10.1007/s11095-016-1958-5 |