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2026

Journal Article

Alpha-particle therapy with an actinium-225 labeled bivalent inhibitor of prostate-specific membrane antigen is therapeutically efficacious in a mouse model of prostate cancer

Morgan, Katherine A., Grieve, Melyssa L., Akhter, Dewan T., Lange, Jaclyn L., Harris, Matthew J., Thurecht, Kristofer J., Paterson, Brett M. and Donnelly, Paul S. (2026). Alpha-Particle Therapy with an Actinium-225 Labeled Bivalent Inhibitor of Prostate-Specific Membrane Antigen is Therapeutically Efficacious in a Mouse Model of Prostate Cancer. Journal of Medicinal Chemistry acs.jmedchem.6c01378. doi: 10.1021/acs.jmedchem.6c01378

Alpha-particle therapy with an actinium-225 labeled bivalent inhibitor of prostate-specific membrane antigen is therapeutically efficacious in a mouse model of prostate cancer

2026

Journal Article

Affinity-Tuned Albumin Hitchhiking Extends the Bioorthogonal Capture Window in Pretargeting Radiotheranostics

He, Xie, Fletcher, Nicholas L., Ediriweera, Gayathri R., Zhu, Yifei, Humphries, James, Howard, Christopher B., Wang, Jiazheng, Bell, Craig A., Kempe, Kristian and Thurecht, Kristofer J. (2026). Affinity-Tuned Albumin Hitchhiking Extends the Bioorthogonal Capture Window in Pretargeting Radiotheranostics. Advanced Healthcare Materials e71385, e71385-e71385. doi: 10.1002/adhm.71385

Affinity-Tuned Albumin Hitchhiking Extends the Bioorthogonal Capture Window in Pretargeting Radiotheranostics

2026

Journal Article

A modular, accessible, and low‐cost photoreactor with precision light and temperature control for small‐scale reactions

Vermeijlen, Irma G., Anderson, Will, Ediriweera, Gayathri R., Fletcher, Nicholas L., Bell, Craig A. and Thurecht, Kristofer J. (2026). A modular, accessible, and low‐cost photoreactor with precision light and temperature control for small‐scale reactions. Chemistry–Methods, 6 (6) e70122, 1-11. doi: 10.1002/cmtd.70122

A modular, accessible, and low‐cost photoreactor with precision light and temperature control for small‐scale reactions

2026

Journal Article

Cell-Mimetic Antifouling Poly(ethylene glycol) Interface Enables Selective Capture and Viable Release of Circulating Tumor Cells

Li, Mengqi, Pan, Haoyuan, Zuo, Liping, Howard, Christopher B., Thurecht, Kristofer J., Yu, Qun, Gao, Zhiliang, Cui, Jiwei and Hao, Jingcheng (2026). Cell-Mimetic Antifouling Poly(ethylene glycol) Interface Enables Selective Capture and Viable Release of Circulating Tumor Cells. The Journal of Physical Chemistry B, 130 (22) acs.jpcb.6c01974, 5811-5818. doi: 10.1021/acs.jpcb.6c01974

Cell-Mimetic Antifouling Poly(ethylene glycol) Interface Enables Selective Capture and Viable Release of Circulating Tumor Cells

2026

Journal Article

Assessing Value for Money in Theranostic Nuclear Medicine: A Systematic Review

Wang, Yufan, Wood, James L., Thurecht, Kristofer J., Yeoh, Su Yu and Tuffaha, Haitham (2026). Assessing Value for Money in Theranostic Nuclear Medicine: A Systematic Review. Journal of Nuclear Medicine, jnumed.125.271469-jnumed.125.271469. doi: 10.2967/jnumed.125.271469

Assessing Value for Money in Theranostic Nuclear Medicine: A Systematic Review

2026

Journal Article

Utilizing biorecognition to prime tumors for enhanced nanomedicine delivery of alpha therapies

Fletcher, Nicholas L., Chu, Weijing, Huda, Pie, Prior, Amber, S., Gayathri, Humphries, James, Howard, Christopher, Wood, James L., Zhang, Xiaoyan, Silva, Marina Silveira E., Lum, Benedict, Lim, Malcolm, Simpson, Fiona and Thurecht, Kristofer J. (2026). Utilizing biorecognition to prime tumors for enhanced nanomedicine delivery of alpha therapies. Journal of Controlled Release, 392 114708, 114708. doi: 10.1016/j.jconrel.2026.114708

Utilizing biorecognition to prime tumors for enhanced nanomedicine delivery of alpha therapies

2026

Journal Article

Poly(2-oxazoline) and poly(2-oxazine)-based nanomedicines: advancements, opportunities and challenges

Humphries, James, Warne, Nicole M., Feeney, Orlagh M., Thurecht, Kristofer J. and Kempe, Kristian (2026). Poly(2-oxazoline) and poly(2-oxazine)-based nanomedicines: advancements, opportunities and challenges. Journal of Controlled Release, 394 114838. doi: 10.1016/j.jconrel.2026.114838

Poly(2-oxazoline) and poly(2-oxazine)-based nanomedicines: advancements, opportunities and challenges

2026

Journal Article

Engineered protein corona by bispecific antibody endows liposome with enhanced tumor targeting ability and mitigated accelerated blood clearance effect

Wei, Xiaoli, Ding, Tianhao, Xi, Meili, Thurecht, Kristofer J., Howard, Christopher B., Cui, Jiwei, Zhan, Changyou and Zhang, Zui (2026). Engineered protein corona by bispecific antibody endows liposome with enhanced tumor targeting ability and mitigated accelerated blood clearance effect. Nano Today, 66 102923, 102923. doi: 10.1016/j.nantod.2025.102923

Engineered protein corona by bispecific antibody endows liposome with enhanced tumor targeting ability and mitigated accelerated blood clearance effect

2026

Journal Article

Trans-endothelial trafficking in zebrafish: nanobio interactions of polyethylene glycol-based nanoparticles in live vasculature

Lim, Ye-Wheen, Bell, Craig A., Fletcher, Nicholas L., Condon, Nicholas D., Akhter, Dewan T., Rae, James, Ferguson, Charles, Martel, Nick, Humphries, James, Lo, Harriet P., Wu, Yeping, Houston, Zachary H., Lagendijk, Anne K., Hall, Thomas E., Thurecht, Kristofer J. and Parton, Robert G. (2026). Trans-endothelial trafficking in zebrafish: nanobio interactions of polyethylene glycol-based nanoparticles in live vasculature. ACS Nano, 20 (3), 3132-3155. doi: 10.1021/acsnano.5c21042

Trans-endothelial trafficking in zebrafish: nanobio interactions of polyethylene glycol-based nanoparticles in live vasculature

2026

Journal Article

Synthesis and Evaluation of D8W, an Octadentate Desferrioxamine Analogue with Enhanced Water Solubility Designed for 89 Zr-ImmunoPET Imaging

Wood, James L., Ghosh, Saikat, Rosser, Callum A., Feeney, Samuel V., Brown, Christopher J. M., Fletcher, Nicholas L., Wheatcroft, Michael P., Thurecht, Kristofer J. and Codd, Rachel (2026). Synthesis and Evaluation of D8W, an Octadentate Desferrioxamine Analogue with Enhanced Water Solubility Designed for 89 Zr-ImmunoPET Imaging. Molecular Pharmaceutics, 23 (3) acs.molpharmaceut.5c01947, 1-14. doi: 10.1021/acs.molpharmaceut.5c01947

Synthesis and Evaluation of D8W, an Octadentate Desferrioxamine Analogue with Enhanced Water Solubility Designed for 89 Zr-ImmunoPET Imaging

2026

Journal Article

Pretargeted polymeric systems for conducting chemo-radiotherapy on glioblastoma: an evaluation of the impact of nanomedicine structure on bioorthogonal chemistry in vivo

Chu, Weijing, Ediriweera, Gayathri R., Prior, Amber, Huda, Pie, Lum, Benedict, Howard, Christopher B., Fletcher, Nicholas L., Bernhardt, Paul V. and Thurecht, Kristofer J. (2026). Pretargeted polymeric systems for conducting chemo-radiotherapy on glioblastoma: an evaluation of the impact of nanomedicine structure on bioorthogonal chemistry in vivo. Biomacromolecules, 27 (1), 205-216. doi: 10.1021/acs.biomac.5c01157

Pretargeted polymeric systems for conducting chemo-radiotherapy on glioblastoma: an evaluation of the impact of nanomedicine structure on bioorthogonal chemistry in vivo

2025

Journal Article

A modular encapsulation system for precision delivery of proteins, nucleic acids, and small molecules

Luong, Thai D., Martel, Nick, Rae, James, Lo, Harriet P., Lim, Ye-Wheen, Wu, Yeping, McMahon, Kerrie-Ann, Sun, Haolan, Fletcher, Nicholas L., Thurecht, Kristofer J., Johnston, Angus P. R., Ariotti, Nicholas, Hall, Thomas E. and Parton, Robert G. (2025). A modular encapsulation system for precision delivery of proteins, nucleic acids, and small molecules. ACS Nano, 19 (50), 42079-42096. doi: 10.1021/acsnano.5c11452

A modular encapsulation system for precision delivery of proteins, nucleic acids, and small molecules

2025

Conference Publication

Pre-targeting of PEG-based nanomedicines: precise delivery of potent payloads

Fletcher, Nicholas, Thurecht, Kristofer, Chu, Weijing, Huda, Pie, Humphries, James and Wood, James (2025). Pre-targeting of PEG-based nanomedicines: precise delivery of potent payloads. International Symposium on Radiopharmaceutical Sciences iSRS 2025, Gold Coast, QLD, Australia, 11-15 May 2025. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.nucmedbio.2025.109150

Pre-targeting of PEG-based nanomedicines: precise delivery of potent payloads

2025

Conference Publication

Evaluating mRNA delivery using nuclear medicine

Humphries, James, Witjaksono, Andrea, Poudel, Abishek, Mardon, Karine, Migotto, Mary-Anne, Cheetham, Seth, Howard, Christopher and Thurecht, Kristofer (2025). Evaluating mRNA delivery using nuclear medicine. International Symposium on Radiopharmaceutical Sciences iSRS 2025, Gold Coast, QLD, Australia, 11-15 May 2025. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.nucmedbio.2025.109117

Evaluating mRNA delivery using nuclear medicine

2025

Journal Article

Preclinical evaluation of [212Pb]Pb-ADVC001: a prostate-specific membrane antigen–targeted α-therapy for prostate cancer

Liu, Feifei, Monterosso, Melissa E., Boucher, Didier, Shakti, Stelle, Li, Kwong Ching, Kim, Chanwoo, Prior, Amber, Sydes, Abby, Soderholm, Amelia T., Fletcher, Nicholas, Akhter, Dewan, Thurecht, Kristofer, Tieu, William, Kuan, Kevin, Horsfall, Aimee, Kumar, Saawan, Koehbach, Johannes, Hammond, Edward, Karmann, Anna, Rose, Stephen, Li, Gary, Puttick, Simon and Kryza, Thomas (2025). Preclinical evaluation of [212Pb]Pb-ADVC001: a prostate-specific membrane antigen–targeted α-therapy for prostate cancer. Journal of Nuclear Medicine, 66 (11), 1-11. doi: 10.2967/jnumed.125.269707

Preclinical evaluation of [212Pb]Pb-ADVC001: a prostate-specific membrane antigen–targeted α-therapy for prostate cancer

2025

Conference Publication

Development of novel MnO2-based nanoparticles for PET/MRI-guided Alpha Therapy

Gulzar, Arif, Wang, Yanan, Balaji, Arunpandian, Fletcher, Nicholas and Thurecht, Kristofer (2025). Development of novel MnO2-based nanoparticles for PET/MRI-guided Alpha Therapy. International Symposium on Radiopharmaceutical Sciences iSRS 2025, Gold Coast, QLD Australia, 11-15 May 2025. Elsevier BV. doi: 10.1016/j.nucmedbio.2025.109532

Development of novel MnO2-based nanoparticles for PET/MRI-guided Alpha Therapy

2025

Conference Publication

Optimising VHH-based radiopharmaceuticals: addressing pharmacokinetics and renal clearance challenges

Huda, Pie, Owen, David, Bell, Craig, Wood, James, Humphries, James and Thurecht, Kristofer (2025). Optimising VHH-based radiopharmaceuticals: addressing pharmacokinetics and renal clearance challenges. International Symposium on Radiopharmaceutical Sciences iSRS 2025, Gold Coast, QLD, Australia, 11-15 May 2025. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.nucmedbio.2025.109460

Optimising VHH-based radiopharmaceuticals: addressing pharmacokinetics and renal clearance challenges

2025

Conference Publication

Development of thiosemicarbazonato technetium-99m complexes for SPECT imaging

Maclean, Rachel, Fletcher, Nicholas, Alsadig, Ahmed, Chu, Weijing, Sihver, Wiebke, Baraban, Larysa, Thurecht, Kristofer, Kubeil, Manja, Tuck, Kellie and Paterson, Brett (2025). Development of thiosemicarbazonato technetium-99m complexes for SPECT imaging. International Symposium on Radiopharmaceutical Sciences iSRS 2025, Gold Coast, QLD, Australia, 11-15 May 2025. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.nucmedbio.2025.109249

Development of thiosemicarbazonato technetium-99m complexes for SPECT imaging

2025

Conference Publication

Optimizing 64Cu production: an efficient approach to 64Ni target material recycling

Barkhausen, Christoph, Stimson, Damion, Najdovski, Ljubco, Poniger, Stan and Thurecht, Kristofer (2025). Optimizing 64Cu production: an efficient approach to 64Ni target material recycling. International Symposium on Radiopharmaceutical Sciences iSRS 2025, Gold Coast, QLD, Australia, 11-15 May 2025. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.nucmedbio.2025.109243

Optimizing 64Cu production: an efficient approach to 64Ni target material recycling

2025

Conference Publication

Trifunctional albumin-binding constructs for optimisation of in vivo delivery of cancer radio-theranostics

He, Xie (Kate), Thurecht, Kristofer, Fletcher, Nicholas, Bell, Craig and Kempe, Kristian (2025). Trifunctional albumin-binding constructs for optimisation of in vivo delivery of cancer radio-theranostics. International Symposium on Radiopharmaceutical Sciences iSRS 2025, Gold Coast, QLD, Australia, 11-15 May 2025. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.nucmedbio.2025.109457

Trifunctional albumin-binding constructs for optimisation of in vivo delivery of cancer radio-theranostics