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2026 Journal Article Utilizing biorecognition to prime tumors for enhanced nanomedicine delivery of alpha therapiesFletcher, Nicholas L., Chu, Weijing, Huda, Pie, Prior, Amber, S., Gayathri, Humphries, James, Howard, Christopher, Wood, James L., Zhang, Xiaoyan, Silva, Marina Silveira E., Lum, Benedict, Lim, Malcolm, Simpson, Fiona and Thurecht, Kristofer J. (2026). Utilizing biorecognition to prime tumors for enhanced nanomedicine delivery of alpha therapies. Journal of Controlled Release, 392 114708, 114708. doi: 10.1016/j.jconrel.2026.114708 |
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2026 Journal Article Engineered protein corona by bispecific antibody endows liposome with enhanced tumor targeting ability and mitigated accelerated blood clearance effectWei, Xiaoli, Ding, Tianhao, Xi, Meili, Thurecht, Kristofer J., Howard, Christopher B., Cui, Jiwei, Zhan, Changyou and Zhang, Zui (2026). Engineered protein corona by bispecific antibody endows liposome with enhanced tumor targeting ability and mitigated accelerated blood clearance effect. Nano Today, 66 102923, 102923. doi: 10.1016/j.nantod.2025.102923 |
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2026 Journal Article Trans-endothelial trafficking in zebrafish: nanobio interactions of polyethylene glycol-based nanoparticles in live vasculatureLim, Ye-Wheen, Bell, Craig A., Fletcher, Nicholas L., Condon, Nicholas D., Akhter, Dewan T., Rae, James, Ferguson, Charles, Martel, Nick, Humphries, James, Lo, Harriet P., Wu, Yeping, Houston, Zachary H., Lagendijk, Anne K., Hall, Thomas E., Thurecht, Kristofer J. and Parton, Robert G. (2026). Trans-endothelial trafficking in zebrafish: nanobio interactions of polyethylene glycol-based nanoparticles in live vasculature. ACS Nano, 20 (3), 3132-3155. doi: 10.1021/acsnano.5c21042 |
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2026 Journal Article Synthesis and Evaluation of D8W, an Octadentate Desferrioxamine Analogue with Enhanced Water Solubility Designed for 89 Zr-ImmunoPET ImagingWood, James L., Ghosh, Saikat, Rosser, Callum A., Feeney, Samuel V., Brown, Christopher J. M., Fletcher, Nicholas L., Wheatcroft, Michael P., Thurecht, Kristofer J. and Codd, Rachel (2026). Synthesis and Evaluation of D8W, an Octadentate Desferrioxamine Analogue with Enhanced Water Solubility Designed for 89 Zr-ImmunoPET Imaging. Molecular Pharmaceutics, 23 (3) acs.molpharmaceut.5c01947, 1-14. doi: 10.1021/acs.molpharmaceut.5c01947 |
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2026 Journal Article Pretargeted polymeric systems for conducting chemo-radiotherapy on glioblastoma: an evaluation of the impact of nanomedicine structure on bioorthogonal chemistry in vivoChu, Weijing, Ediriweera, Gayathri R., Prior, Amber, Huda, Pie, Lum, Benedict, Howard, Christopher B., Fletcher, Nicholas L., Bernhardt, Paul V. and Thurecht, Kristofer J. (2026). Pretargeted polymeric systems for conducting chemo-radiotherapy on glioblastoma: an evaluation of the impact of nanomedicine structure on bioorthogonal chemistry in vivo. Biomacromolecules, 27 (1), 205-216. doi: 10.1021/acs.biomac.5c01157 |
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2025 Journal Article A modular encapsulation system for precision delivery of proteins, nucleic acids, and small moleculesLuong, Thai D., Martel, Nick, Rae, James, Lo, Harriet P., Lim, Ye-Wheen, Wu, Yeping, McMahon, Kerrie-Ann, Sun, Haolan, Fletcher, Nicholas L., Thurecht, Kristofer J., Johnston, Angus P. R., Ariotti, Nicholas, Hall, Thomas E. and Parton, Robert G. (2025). A modular encapsulation system for precision delivery of proteins, nucleic acids, and small molecules. ACS Nano, 19 (50), 42079-42096. doi: 10.1021/acsnano.5c11452 |
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2025 Conference Publication Optimizing 64Cu production: an efficient approach to 64Ni target material recyclingBarkhausen, Christoph, Stimson, Damion, Najdovski, Ljubco, Poniger, Stan and Thurecht, Kristofer (2025). Optimizing 64Cu production: an efficient approach to 64Ni target material recycling. International Symposium on Radiopharmaceutical Sciences iSRS 2025, Gold Coast, QLD, Australia, 11-15 May 2025. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.nucmedbio.2025.109243 |
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2025 Conference Publication Trifunctional albumin-binding constructs for optimisation of in vivo delivery of cancer radio-theranosticsHe, Xie (Kate), Thurecht, Kristofer, Fletcher, Nicholas, Bell, Craig and Kempe, Kristian (2025). Trifunctional albumin-binding constructs for optimisation of in vivo delivery of cancer radio-theranostics. International Symposium on Radiopharmaceutical Sciences iSRS 2025, Gold Coast, QLD, Australia, 11-15 May 2025. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.nucmedbio.2025.109457 |
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2025 Conference Publication Targeting the oxytocin receptor for breast cancer imaging and radiotherapyMuttenthaler, Markus, Perisic, Monika, Liu, Huiping, Kalaba, Predrag, Madge, Harrison, Dighe, Satish, Fletcher, Nicholas, Migotto, Mary-Anne, Mardon, Karine, Thurecht, Kristofer, Keimpema, Erik and Gruber, Christian (2025). Targeting the oxytocin receptor for breast cancer imaging and radiotherapy. International Symposium on Radiopharmaceutical Sciences iSRS 2025, Gold Coast, QLD, Australia, 11-15 May 2025. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.nucmedbio.2025.109302 |
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2025 Conference Publication D2 – Enabling a theranostic approach with 89Zr/177Lu in a single trifunctional ligand scaffoldWood, James, Ghosh, Saikat, Houston, Zachary, Fletcher, Nicholas, Humphries, James, Mardon, Karine, Akhter, Dewan, Tieu, William, Ivashkevich, Alesia, Wheatcroft, Michael, Thurecht, Kristofer and Codd, Rachel (2025). D2 – Enabling a theranostic approach with 89Zr/177Lu in a single trifunctional ligand scaffold. International Symposium on Radiopharmaceutical Sciences iSRS 2025, Gold Coast, QLD, Australia, 11-15 May 2025. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.nucmedbio.2025.109244 |
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2025 Conference Publication Pre-targeting of PEG-based nanomedicines: precise delivery of potent payloadsFletcher, Nicholas, Thurecht, Kristofer, Chu, Weijing, Huda, Pie, Humphries, James and Wood, James (2025). Pre-targeting of PEG-based nanomedicines: precise delivery of potent payloads. International Symposium on Radiopharmaceutical Sciences iSRS 2025, Gold Coast, QLD, Australia, 11-15 May 2025. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.nucmedbio.2025.109150 |
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2025 Conference Publication Evaluating mRNA delivery using nuclear medicineHumphries, James, Witjaksono, Andrea, Poudel, Abishek, Mardon, Karine, Migotto, Mary-Anne, Cheetham, Seth, Howard, Christopher and Thurecht, Kristofer (2025). Evaluating mRNA delivery using nuclear medicine. International Symposium on Radiopharmaceutical Sciences iSRS 2025, Gold Coast, QLD, Australia, 11-15 May 2025. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.nucmedbio.2025.109117 |
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2025 Journal Article Preclinical evaluation of [212Pb]Pb-ADVC001: a prostate-specific membrane antigen–targeted α-therapy for prostate cancerLiu, Feifei, Monterosso, Melissa E., Boucher, Didier, Shakti, Stelle, Li, Kwong Ching, Kim, Chanwoo, Prior, Amber, Sydes, Abby, Soderholm, Amelia T., Fletcher, Nicholas, Akhter, Dewan, Thurecht, Kristofer, Tieu, William, Kuan, Kevin, Horsfall, Aimee, Kumar, Saawan, Koehbach, Johannes, Hammond, Edward, Karmann, Anna, Rose, Stephen, Li, Gary, Puttick, Simon and Kryza, Thomas (2025). Preclinical Evaluation of [212Pb]Pb-ADVC001: A Prostate-Specific Membrane Antigen–Targeted α-Therapy for Prostate Cancer. Journal of Nuclear Medicine, 66 (11), jnumed.125.269707-1713. doi: 10.2967/jnumed.125.269707 |
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2025 Journal Article Development of novel MnO2-based nanoparticles for PET/MRI-guided Alpha TherapyGulzar, Arif, Wang, Yanan, Balaji, Arunpandian, Fletcher, Nicholas and Thurecht, Kristofer (2025). Development of novel MnO2-based nanoparticles for PET/MRI-guided Alpha Therapy. Nuclear Medicine and Biology, 150-151 109532, 109532. doi: 10.1016/j.nucmedbio.2025.109532 |
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2025 Conference Publication Optimising VHH-based radiopharmaceuticals: addressing pharmacokinetics and renal clearance challengesHuda, Pie, Owen, David, Bell, Craig, Wood, James, Humphries, James and Thurecht, Kristofer (2025). Optimising VHH-based radiopharmaceuticals: addressing pharmacokinetics and renal clearance challenges. International Symposium on Radiopharmaceutical Sciences iSRS 2025, Gold Coast, QLD, Australia, 11-15 May 2025. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.nucmedbio.2025.109460 |
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2025 Conference Publication Development of thiosemicarbazonato technetium-99m complexes for SPECT imagingMaclean, Rachel, Fletcher, Nicholas, Alsadig, Ahmed, Chu, Weijing, Sihver, Wiebke, Baraban, Larysa, Thurecht, Kristofer, Kubeil, Manja, Tuck, Kellie and Paterson, Brett (2025). Development of thiosemicarbazonato technetium-99m complexes for SPECT imaging. International Symposium on Radiopharmaceutical Sciences iSRS 2025, Gold Coast, QLD, Australia, 11-15 May 2025. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.nucmedbio.2025.109249 |
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2025 Journal Article The evolution of nanomedicine: the rise of next-generation nanomaterials in cancer nanomedicineForgham, Helen, Chang, Yixin, Wang, Yao, Zhu, Jiayuan, Liu, Liwei, Biggs, Heather, Kakinen, Aleksandr, Jiang, Yuhao, You, Xinru, Thurecht, Kristofer J., Ma, Shaohua, Ju, Lining Arnold, Tao, Wei, Davis, Thomas P., Wong, Joyce Y. and Qiao, Ruirui (2025). The evolution of nanomedicine: the rise of next-generation nanomaterials in cancer nanomedicine. Science Advances, 11 (43) eadx1576, 1-18. doi: 10.1126/sciadv.adx1576 |
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2025 Conference Publication The glycogen synthase kinase-3β inhibitor 9-ING-41 in combination with chemoimmunotherapy provides long-term survival in the Th-MYCN mouse modelMurray, Jayne, Somers, Klaartje, Mak, Crystal, Alfred, Stephanie, Brand, Jennifer, Poon, Evon, Fletcher, Nicholas, Li, Pei, Thurecht, Kristofer, Gray, Juliet, Pearson, Andrew Dj., Chesler, Louis, Hogarty, Michael D., Giles, Francis, Fletcher, Jamie, Ziegler, David S., Norris, Murray D. and Haber, Michelle (2025). The glycogen synthase kinase-3β inhibitor 9-ING-41 in combination with chemoimmunotherapy provides long-term survival in the Th-MYCN mouse model. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. doi: 10.1158/1535-7163.TARG-25-B079 |
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2025 Journal Article Development of a novel engineered antibody format for PSMA-targeted radionuclide therapyFletcher, Nicholas L., Houston, Zachary H., Chandler, Peter G., Yan, Eddie, Holgate, Rob, Wheatcroft, Michael and Thurecht, Kristofer J. (2025). Development of a novel engineered antibody format for PSMA-targeted radionuclide therapy. Molecular Pharmaceutics, 22 (7), 3666-3678. doi: 10.1021/acs.molpharmaceut.4c01193 |
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2025 Conference Publication Retrofitting a cyclotron solid target processing system for radiometal production at AIBN, cyclotron and radiochemistry capabilityStimson, Damion, Barkhausen, Christoph, Najdovski, Ljubco, Gulza, Arif, Dixon, Carl, Maillet, Donald and Thurecht, Kristofer (2025). Retrofitting a cyclotron solid target processing system for radiometal production at AIBN, cyclotron and radiochemistry capability. ANZSNM ASM 2025, Melbourne, VIC Australia, 23-25 May 2025. Hoboken, NJ, United States: Wiley. doi: 10.1111/imj.70120 |
