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2026 Journal Article Engineered protein corona by bispecific antibody endows liposome with enhanced tumor targeting ability and mitigated accelerated blood clearance effectWei, Xiaoli, Ding, Tianhao, Xi, Meili, Thurecht, Kristofer J., Howard, Christopher B., Cui, Jiwei, Zhan, Changyou and Zhang, Zui (2026). Engineered protein corona by bispecific antibody endows liposome with enhanced tumor targeting ability and mitigated accelerated blood clearance effect. Nano Today, 66 102923, 102923. doi: 10.1016/j.nantod.2025.102923 |
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2025 Journal Article A modular encapsulation system for precision delivery of proteins, nucleic acids, and small moleculesLuong, Thai D., Martel, Nick, Rae, James, Lo, Harriet P., Lim, Ye-Wheen, Wu, Yeping, McMahon, Kerrie-Ann, Sun, Haolan, Fletcher, Nicholas L., Thurecht, Kristofer J., Johnston, Angus P. R., Ariotti, Nicholas, Hall, Thomas E. and Parton, Robert G. (2025). A modular encapsulation system for precision delivery of proteins, nucleic acids, and small molecules. ACS Nano acsnano.5c11452. doi: 10.1021/acsnano.5c11452 |
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2025 Journal Article Pretargeted polymeric systems for conducting chemo-radiotherapy on glioblastoma: an evaluation of the impact of nanomedicine structure on bioorthogonal chemistry in vivoChu, Weijing, Ediriweera, Gayathri R., Prior, Amber, Huda, Pie, Lum, Benedict, Howard, Christopher B., Fletcher, Nicholas L., Bernhardt, Paul V. and Thurecht, Kristofer J. (2025). Pretargeted polymeric systems for conducting chemo-radiotherapy on glioblastoma: an evaluation of the impact of nanomedicine structure on bioorthogonal chemistry in vivo. Biomacromolecules acs.biomac.5c01157. doi: 10.1021/acs.biomac.5c01157 |
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2025 Journal Article Optimizing 64Cu Production: An Efficient Approach to 64Ni Target Material RecyclingBarkhausen, Christoph, Stimson, Damion, Najdovski, Ljubco, Poniger, Stan and Thurecht, Kristofer (2025). Optimizing 64Cu Production: An Efficient Approach to 64Ni Target Material Recycling. Nuclear Medicine and Biology, 150-151 109243, 109243-150. doi: 10.1016/j.nucmedbio.2025.109243 |
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2025 Journal Article Trifunctional Albumin-Binding Constructs for Optimisation of In Vivo Delivery of Cancer Radio-TheranosticsHe, Xie (Kate), Thurecht, Kristofer, Fletcher, Nicholas, Bell, Craig and Kempe, Kristian (2025). Trifunctional Albumin-Binding Constructs for Optimisation of In Vivo Delivery of Cancer Radio-Theranostics. Nuclear Medicine and Biology, 150-151 109457, 109457. doi: 10.1016/j.nucmedbio.2025.109457 |
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2025 Journal Article Targeting the Oxytocin Receptor for Breast Cancer Imaging and RadiotherapyMuttenthaler, Markus, Perisic, Monika, Liu, Huiping, Kalaba, Predrag, Madge, Harrison, Dighe, Satish, Fletcher, Nicholas, Migotto, Mary-anne, Mardon, Karine, Thurecht, Kristofer, Keimpema, Erik and Gruber, Christian (2025). Targeting the Oxytocin Receptor for Breast Cancer Imaging and Radiotherapy. Nuclear Medicine and Biology, 150-151 109302, 109302. doi: 10.1016/j.nucmedbio.2025.109302 |
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2025 Journal Article D2 – Enabling a theranostic approach with 89Zr/177Lu in a single trifunctional ligand scaffoldWood, James, Ghosh, Saikat, Houston, Zachary, Fletcher, Nicholas, Humphries, James, Mardon, Karine, Akhter, Dewan, Tieu, William, Ivashkevich, Alesia, Wheatcroft, Michael, Thurecht, Kristofer and Codd, Rachel (2025). D2 – Enabling a theranostic approach with 89Zr/177Lu in a single trifunctional ligand scaffold. Nuclear Medicine and Biology, 150-151 109244, 109244. doi: 10.1016/j.nucmedbio.2025.109244 |
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2025 Journal Article Pre-targeting of PEG-based nanomedicines: precise delivery of potent payloadsFletcher, Nicholas, Thurecht, Kristofer, Chu, Weijing, Huda, Pie, Humphries, James and Wood, James (2025). Pre-targeting of PEG-based nanomedicines: precise delivery of potent payloads. Nuclear Medicine and Biology, 150-151 109150, 109150. doi: 10.1016/j.nucmedbio.2025.109150 |
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2025 Journal Article Evaluating mRNA Delivery Using Nuclear MedicineHumphries, James, Witjaksono, Andrea, Poudel, Abishek, Mardon, Karine, Migotto, Mary-anne, Cheetham, Seth, Howard, Christopher and Thurecht, Kristofer (2025). Evaluating mRNA Delivery Using Nuclear Medicine. Nuclear Medicine and Biology, 150-151 109117, 109117. doi: 10.1016/j.nucmedbio.2025.109117 |
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2025 Journal Article Development of novel MnO2-based nanoparticles for PET/MRI-guided Alpha TherapyGulzar, Arif, Wang, Yanan, Balaji, Arunpandian, Fletcher, Nicholas and Thurecht, Kristofer (2025). Development of novel MnO2-based nanoparticles for PET/MRI-guided Alpha Therapy. Nuclear Medicine and Biology, 150-151 109532, 109532. doi: 10.1016/j.nucmedbio.2025.109532 |
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2025 Journal Article Optimising VHH-Based Radiopharmaceuticals: Addressing Pharmacokinetics and Renal Clearance ChallengesHuda, Pie, Owen, David, Bell, Craig, Wood, James, Humphries, James and Thurecht, Kristofer (2025). Optimising VHH-Based Radiopharmaceuticals: Addressing Pharmacokinetics and Renal Clearance Challenges. Nuclear Medicine and Biology, 150-151 109460, 109460. doi: 10.1016/j.nucmedbio.2025.109460 |
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2025 Journal Article Development of Thiosemicarbazonato Technetium-99m Complexes for SPECT ImagingMaclean, Rachel, Fletcher, Nicholas, Alsadig, Ahmed, Chu, Weijing, Sihver, Wiebke, Baraban, Larysa, Thurecht, Kristofer, Kubeil, Manja, Tuck, Kellie and Paterson, Brett (2025). Development of Thiosemicarbazonato Technetium-99m Complexes for SPECT Imaging. Nuclear Medicine and Biology, 150-151 109249, 109249. doi: 10.1016/j.nucmedbio.2025.109249 |
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2025 Journal Article The evolution of nanomedicine: The rise of next-generation nanomaterials in cancer nanomedicineForgham, Helen, Chang, Yixin, Wang, Yao, Zhu, Jiayuan, Liu, Liwei, Biggs, Heather, Kakinen, Aleksandr, Jiang, Yuhao, You, Xinru, Thurecht, Kristofer J., Ma, Shaohua, Ju, Lining Arnold, Tao, Wei, Davis, Thomas P., Wong, Joyce Y. and Qiao, Ruirui (2025). The evolution of nanomedicine: The rise of next-generation nanomaterials in cancer nanomedicine. Science Advances, 11 (43) eadx1576, eadx1576. doi: 10.1126/sciadv.adx1576 |
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2025 Journal Article Preclinical Evaluation of [<sup>212</sup>Pb]Pb-ADVC001: A Prostate-Specific Membrane Antigen–Targeted α-Therapy for Prostate CancerLiu, Feifei, Monterosso, Melissa E., Boucher, Didier, Shakti, Stelle, Li, Kwong Ching, Kim, Chanwoo, Prior, Amber, Sydes, Abby, Soderholm, Amelia T., Fletcher, Nicholas, Akhter, Dewan, Thurecht, Kristofer, Tieu, William, Kuan, Kevin, Horsfall, Aimee, Kumar, Saawan, Koehbach, Johannes, Hammond, Edward, Karmann, Anna, Rose, Stephen, Li, Gary, Puttick, Simon and Kryza, Thomas (2025). Preclinical Evaluation of [212Pb]Pb-ADVC001: A Prostate-Specific Membrane Antigen–Targeted α-Therapy for Prostate Cancer. Journal of Nuclear Medicine, 66 (11), jnumed.125.269707-1713. doi: 10.2967/jnumed.125.269707 |
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2025 Journal Article Development of a novel engineered antibody format for PSMA-targeted radionuclide therapyFletcher, Nicholas L., Houston, Zachary H., Chandler, Peter G., Yan, Eddie, Holgate, Rob, Wheatcroft, Michael and Thurecht, Kristofer J. (2025). Development of a novel engineered antibody format for PSMA-targeted radionuclide therapy. Molecular Pharmaceutics, 22 (7), 3666-3678. doi: 10.1021/acs.molpharmaceut.4c01193 |
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2025 Journal Article Targeted mRNA delivery with bispecific antibodies that tether LNPs to cell-surface markersDietmair, Bettina, Humphries, James, Mercer, Timothy R., Thurecht, Kristofer J., Howard, Christopher B. and Cheetham, Seth W. (2025). Targeted mRNA delivery with bispecific antibodies that tether LNPs to cell-surface markers. Molecular Therapy Nucleic Acids, 36 (2) 102520, 1-7. doi: 10.1016/j.omtn.2025.102520 |
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2025 Journal Article Immune-modulating nanomedicines for enhanced drug delivery to non-small-cell lung cancerLiu, Feifei, Howard, Christopher B., Huda, Pie, Fletcher, Nicholas L., Bell, Craig A., Blakey, Idriss, Agrez, Michael and Thurecht, Kristofer J. (2025). Immune-modulating nanomedicines for enhanced drug delivery to non-small-cell lung cancer. Biomaterials, 317 123089, 1-14. doi: 10.1016/j.biomaterials.2025.123089 |
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2025 Journal Article Receptor CDCP1 is a potential target for personalized imaging and treatment of poor outcome HER2+, triple negative and metastatic ER+/HER2- breast cancersGough, Madeline, Kwah, Kayden KX., Khan, Tashbib, Ghosh, Saikat, Sun, Biao, Lee, Catherine YJ., Sokolowski, Kamil A., Tse, Brian WC., Wickramasuriya, Lashith, Ferguson, Kaltin, Rogers, Rebecca, Goh, Justin B., Fletcher, Nicholas L., Houston, Zachary H., Thurecht, Kristofer J., Bray, Laura J., Liu, Cheng, Pyke, Christopher, Lim, Elgene, Snell, Cameron E., He, Yaowu, Hooper, John D. and Kryza, Thomas (2025). Receptor CDCP1 is a potential target for personalized imaging and treatment of poor outcome HER2+, triple negative and metastatic ER+/HER2- breast cancers. Clinical Cancer Research, 31 (8), 1504-1519. doi: 10.1158/1078-0432.ccr-24-2865 |
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2025 Journal Article Harnessing nanoparticles and bioorthogonal chemistries for improving precision of nuclear medicineEdiriweera, Gayathri R., Li, Mengdie, Fletcher, Nicholas L., Houston, Zachary H., Ahamed, Muneer, Blakey, Idriss and Thurecht, Kristofer J. (2025). Harnessing nanoparticles and bioorthogonal chemistries for improving precision of nuclear medicine. Biomaterials Science, 13 (9), 2297-2319. doi: 10.1039/d4bm01387e |
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2025 Journal Article Lipid nanoparticles and transcranial focused ultrasound enhance the delivery of SOD1 antisense oligonucleotides to the murine brain for ALS therapyEdiriweera, Gayathri R., Sivaram, Amal J., Cowin, Gary, Brown, Mikayla L., McAlary, Luke, Lum, Jeremy S., Fletcher, Nicholas L., Robinson, Liam, Simpson, Joshua D., Chen, Liyu, Wasielewska, Joanna M., Byrne, Ella, Finnie, John W., Manavis, Jim, White, Anthony R., Yerbury, Justin J., Thurecht, Kristofer J. and Vine, Kara L. (2025). Lipid nanoparticles and transcranial focused ultrasound enhance the delivery of SOD1 antisense oligonucleotides to the murine brain for ALS therapy. Journal of Controlled Release, 378, 221-235. doi: 10.1016/j.jconrel.2024.11.074 |
