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2023 Journal Article Efficient delivery of Temozolomide using ultrasmall large-pore silica nanoparticles for glioblastomaJanjua, Taskeen Iqbal, Cao, Yuxue, Ahmed-Cox, Aria, Raza, Aun, Moniruzzaman, Md, Akhter, Dewan Taslima, Fletcher, Nicholas L., Kavallaris, Maria, Thurecht, Kristofer J. and Popat, Amirali (2023). Efficient delivery of Temozolomide using ultrasmall large-pore silica nanoparticles for glioblastoma. Journal of Controlled Release, 357, 161-174. doi: 10.1016/j.jconrel.2023.03.040 |
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2023 Journal Article Combination of chemotherapy and mild hyperthermia using targeted nanoparticles: a potential treatment modality for breast cancerKaur, Ishdeep, Tieu, Terence, Deepagan, Veerasikku G., Ali, Muhammad A., Alsunaydih, Fahad, Rudd, David, Moghaddam, Maliheh A., Bourgeois, Laure, Adams, Timothy E., Thurecht, Kristofer J., Yuce, Mehmet, Cifuentes-Rius, Anna and Voelcker, Nicolas H. (2023). Combination of chemotherapy and mild hyperthermia using targeted nanoparticles: a potential treatment modality for breast cancer. Pharmaceutics, 15 (5) 1389, 1-23. doi: 10.3390/pharmaceutics15051389 |
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2023 Journal Article Homochiral poly(2‐oxazoline)‐based membrane for efficient enantioselective separationWang, Fanmengjing, Pizzi, David, Lu, Yizhihao, He, Kaiqiang, Thurecht, Kristofer J., Hill, Matthew R., Marriott, Philip, Holl, Mark M. Banaszak, Kempe, Kristian and Wang, Huanting (2023). Homochiral poly(2‐oxazoline)‐based membrane for efficient enantioselective separation. Angewandte Chemie International Edition, 62 (8) e202212139, 1-6. doi: 10.1002/anie.202212139 |
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2023 Journal Article Pharmacokinetics and Biodistribution of Zr-Miltuximab and Its Antibody Fragments as Glypican-1 Targeting Immuno-PET Agents in GlioblastomaGhosh, Saikat, Fletcher, Nicholas L., Huda, Pie, Houston, Zachary H., Howard, Christopher B., Lund, Maria E., Lu, Yanling, Campbell, Douglas H., Walsh, Bradley J. and Thurecht, Kristofer J. (2023). Pharmacokinetics and Biodistribution of Zr-Miltuximab and Its Antibody Fragments as Glypican-1 Targeting Immuno-PET Agents in Glioblastoma. Molecular pharmaceutics, 20 (3), 1549-1563. doi: 10.1021/acs.molpharmaceut.2c00760 |
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2023 Journal Article Enhanced drug delivery to cancer cells through a pH-sensitive polycarbonate platformArno, Maria C., Simpson, Joshua D., Blackman, Lewis D., Brannigan, Ruairí P., Thurecht, Kristofer J. and Dove, Andrew P. (2023). Enhanced drug delivery to cancer cells through a pH-sensitive polycarbonate platform. Biomaterials Science, 11 (3), 908-915. doi: 10.1039/d2bm01626e |
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2022 Journal Article Utilizing PET and MALDI imaging for discovery of a targeted probe for brain endocannabinoid α/β-hydrolase domain 6 (ABHD6)Mardon, Karine, Patel, Jayendra Z., Savinainen, Juha R., Stimson, Damion H. R., Oyagawa, Caitlin R. M., Grimsey, Natasha L., Migotto, Mary-anne, Njiru, Grace F. M., Hamilton, Brett R., Cowin, Gary, Yli-Kauhaluoma, Jari, Vanduffel, Wim, Blakey, Idriss, Bhalla, Rajiv, Cawthorne, Christopher, Celen, Sofie, Bormans, Guy, Thurecht, Kristofer J and Ahamed, Muneer (2022). Utilizing PET and MALDI imaging for discovery of a targeted probe for brain endocannabinoid α/β-hydrolase domain 6 (ABHD6). Journal of Medicinal Chemistry, 66 (1), 538-552. doi: 10.1021/acs.jmedchem.2c01485 |
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2022 Journal Article Probing the biocompatibility and immune cell association of chiral, water-soluble, bottlebrush poly(2-oxazoline)sPizzi, David, Humphries, James, Morrow, Joshua P., Mahmoud, Ayaat M., Fletcher, Nicholas L., Sonderegger, Stefan E., Bell, Craig A., Thurecht, Kristofer J. and Kempe, Kristian (2022). Probing the biocompatibility and immune cell association of chiral, water-soluble, bottlebrush poly(2-oxazoline)s. Biomacromolecules, 24 (1), 246-257. doi: 10.1021/acs.biomac.2c01105 |
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2022 Journal Article Modulating macrophage clearance of nanoparticles: comparison of small-molecule and biologic drugs as pharmacokinetic modifiers of soft nanomaterialsMills, Jessica A., Humphries, James, Simpson, Joshua D., Sonderegger, Stefan E., Thurecht, Kristofer J. and Fletcher, Nicholas L. (2022). Modulating macrophage clearance of nanoparticles: comparison of small-molecule and biologic drugs as pharmacokinetic modifiers of soft nanomaterials. Molecular Pharmaceutics, 19 (11), 4080-4097. doi: 10.1021/acs.molpharmaceut.2c00528 |
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2022 Journal Article Modeling brain metastasis by internal carotid artery injection of cancer cellsLim, Malcolm, Fletcher, Nicholas, Reed, Amy Mccart, Flint, Melanie, Thurecht, Kristofer, Saunus, Jodi and Lakhani, Sunil R. (2022). Modeling brain metastasis by internal carotid artery injection of cancer cells. Journal of Visualized Experiments, 2022 (186) e64216. doi: 10.3791/64216 |
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2022 Journal Article Protected amine-functional initiators for the synthesis of α-amine homo- and heterotelechelic poly(2-ethyl-2-oxazoline)sMazrad, Zihnil A. I., Lai, May, Davis, Thomas P., Nicolazzo, Joseph A., Thurecht, Kristofer J., Leiske, Meike N. and Kempe, Kristian (2022). Protected amine-functional initiators for the synthesis of α-amine homo- and heterotelechelic poly(2-ethyl-2-oxazoline)s. Polymer Chemistry, 13 (30), 4436-4445. doi: 10.1039/d2py00649a |
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2022 Journal Article A novel lipidic peptide with potential to promote balanced effector-regulatory T cell responsesAgrez, Michael, Rzepecka, Justyna, Turner, Darryl, Knox, Gavin, Chandler, Christopher, Howard, Christopher B., Fletcher, Nicholas, Thurecht, Kristofer, Parker, Stephen, Gooding, Hayley and Gallagher, Laura (2022). A novel lipidic peptide with potential to promote balanced effector-regulatory T cell responses. Scientific Reports, 12 (1) 11185, 11185. doi: 10.1038/s41598-022-15455-5 |
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2022 Journal Article Confined microemulsion sono-polymerization of poly(ethylene glycol) nanoparticles for targeted deliveryGao, Zhiliang, Li, Xiaoyu, Zhao, Kaijie, Geng, Huimin, Zhang, Peiyu, Ju, Yi, Huda, Pie, Howard, Christopher B, Thurecht, Kristofer J, Ashokkumar, Muthupandian, Hao, Jingcheng and Cui, Jiwei (2022). Confined microemulsion sono-polymerization of poly(ethylene glycol) nanoparticles for targeted delivery. Chemical Communications, 58 (56), 7777-7780. doi: 10.1039/d2cc01874h |
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2022 Journal Article Pre-targeting of polymeric nanomaterials to balance tumour accumulation and clearanceFletcher, N. L., Prior, A., Choy, O., Humphries, J., Huda, P., Ghosh, S., Houston, Z. H., Bell, C. A. and Thurecht, K. J. (2022). Pre-targeting of polymeric nanomaterials to balance tumour accumulation and clearance. Chemical Communications, 58 (57), 7912-7915. doi: 10.1039/d2cc02443h |
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2022 Journal Article Development of targeted micelles and polymersomes prepared from degradable RAFT-based diblock copolymers and their potential role as nanocarriers for chemotherapeuticsAhmed, Salma E., Fletcher, Nicholas L., Prior, Amber R., Huda, Pie, Bell, Craig A. and Thurecht, Kristofer J. (2022). Development of targeted micelles and polymersomes prepared from degradable RAFT-based diblock copolymers and their potential role as nanocarriers for chemotherapeutics. Polymer Chemistry, 13 (27), 4004-4017. doi: 10.1039/d2py00257d |
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2022 Journal Article Investigation of a dual siRNA/chemotherapy delivery system for breast cancer therapyZhao, Yongmei, Liu, Tianqing, Ardana, Aditya, Fletcher, Nicholas L., Houston, Zachary H., Blakey, Idriss and Thurecht, Kristofer J. (2022). Investigation of a dual siRNA/chemotherapy delivery system for breast cancer therapy. ACS Omega, 7 (20), 17119-17127. doi: 10.1021/acsomega.2c00620 |
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2022 Journal Article Antibody-based formats to target glioblastoma: overcoming barriers to protein drug deliveryGhosh, Saikat, Huda, Pie, Fletcher, Nicholas L., Howard, Christopher B., Walsh, Bradley, Campbell, Douglas, Pinkham, Mark B. and Thurecht, Kristofer J. (2022). Antibody-based formats to target glioblastoma: overcoming barriers to protein drug delivery. Molecular Pharmaceutics, 19 (5), 1233-1247. doi: 10.1021/acs.molpharmaceut.1c00996 |
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2022 Journal Article Template-assisted antibody assembly: a versatile approach for engineering functional antibody nanoparticlesHu, Yingjie, Li, Jianhua, Ju, Yi, Houston, Zachary H., Fletcher, Nicholas L., De Rose, Robert, Fernandes, Soraia, Hagemeyer, Christoph E., Alt, Karen, Thurecht, Kristofer J., Cortez-Jugo, Christina and Caruso, Frank (2022). Template-assisted antibody assembly: a versatile approach for engineering functional antibody nanoparticles. Chemistry of Materials, 34 (8) acs.chemmater.1c04397, 3694-3704. doi: 10.1021/acs.chemmater.1c04397 |
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2022 Journal Article Understanding nanomedicine treatment in an aggressive spontaneous brain cancer model at the stage of early blood brain barrier disruptionJanowicz, Phillip W., Houston, Zachary H., Bunt, Jens, Fletcher, Nicholas L., Bell, Craig A., Cowin, Gary, Howard, Christopher B., Taslima, Dewan, Westra van Holthe, Nicholas, Prior, Amber, Soh, Vanessa, Ghosh, Saikat, Humphries, James, Huda, Pie, Mahler, Stephen M., Richards, Linda J. and Thurecht, Kristofer J. (2022). Understanding nanomedicine treatment in an aggressive spontaneous brain cancer model at the stage of early blood brain barrier disruption. Biomaterials, 283 121416, 121416. doi: 10.1016/j.biomaterials.2022.121416 |
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2022 Journal Article Simultaneous dual echo gadolinium enhanced MR-PET for evaluation of PET tracer delivery in altered pathophysiologyCowin, Gary J, Mardon, Karine, Houston, Zachary H., Bhalla, Rajiv, Stimson, Damion H. R., Thurecht, Kristofer J. and Brereton, Ian M. (2022). Simultaneous dual echo gadolinium enhanced MR-PET for evaluation of PET tracer delivery in altered pathophysiology. Frontiers in Physics, 10 759749. doi: 10.3389/fphy.2022.759749 |
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2022 Journal Article Clinical development of an anti-GPC-1 antibody for the treatment of cancerGhosh, Saikat, Huda, Pie, Fletcher, Nicholas, Campbell, Douglas, Thurecht, Kristofer J. and Walsh, Bradley (2022). Clinical development of an anti-GPC-1 antibody for the treatment of cancer. Expert Opinion on Biological Therapy, 22 (5), 603-613. doi: 10.1080/14712598.2022.2033204 |
