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2019

Journal Article

Innovative therapeutic strategies for effective treatment of brain metastases

Lim, Malcolm, Puttick, Simon, Houston, Zachary H., Thurecht, Kristofer J., Kalita-de Croft, Priyakshi, Mahler, Stephen, Rose, Stephen E., Jeffree, Rosalind L., Mazzieri, Roberta, Dolcetti, Riccardo, Lakhani, Sunil R. and Saunus, Jodi M. (2019). Innovative therapeutic strategies for effective treatment of brain metastases. International Journal of Molecular Sciences, 20 (6) 1280, 1280. doi: 10.3390/ijms20061280

Innovative therapeutic strategies for effective treatment of brain metastases

2019

Journal Article

Modulating targeting of poly(ethylene glycol) particles to tumor cells using bispecific antibodies

Cui, Jiwei, Ju, Yi, Houston, Zachary H., Glass, Joshua J., Fletcher, Nicholas L., Alcantara, Sheilajen, Dai, Qiong, Howard, Christopher B., Mahler, Stephen M., Wheatley, Adam K., De Rose, Robert, Brannon, Paul T., Paterson, Brett M., Donnelly, Paul S., Thurecht, Kristofer J., Caruso, Frank and Kent, Stephen J. (2019). Modulating targeting of poly(ethylene glycol) particles to tumor cells using bispecific antibodies. Advanced Healthcare Materials, 8 (9) 1801607, e1801607. doi: 10.1002/adhm.201801607

Modulating targeting of poly(ethylene glycol) particles to tumor cells using bispecific antibodies

2019

Journal Article

Ultrasound-responsive nanobubbles for enhanced intravitreal drug migration: An ex vivo evaluation

Thakur, Sachin S., Chen, Ying-Shan, Houston, Zachary H., Fletcher, Nicholas, Barnett, Nigel L., Thurecht, Kristofer J., Rupenthal, Ilva D. and Parekh, Harendra S. (2019). Ultrasound-responsive nanobubbles for enhanced intravitreal drug migration: An ex vivo evaluation. European Journal of Pharmaceutics and Biopharmaceutics, 136, 102-107. doi: 10.1016/j.ejpb.2019.01.014

Ultrasound-responsive nanobubbles for enhanced intravitreal drug migration: An ex vivo evaluation

2019

Journal Article

Factorial design-assisted supercritical carbon-dioxide extraction of cytotoxic active principles from Carica papaya leaf juice

Khaw, Kooi-Yeong, Parat, Marie-Odile, Shaw, Paul Nicholas, Nguyen, Thao T. T., Pandey, Saurabh, Thurecht, Kristofer J. and Falconer, James Robert (2019). Factorial design-assisted supercritical carbon-dioxide extraction of cytotoxic active principles from Carica papaya leaf juice. Scientific Reports, 9 (1) 1716, 1716. doi: 10.1038/s41598-018-37171-9

Factorial design-assisted supercritical carbon-dioxide extraction of cytotoxic active principles from Carica papaya leaf juice

2019

Journal Article

Preparation of albendazole-loaded liposomes by supercritical carbon dioxide processing

Maqbool, Faheem, Moyle, Peter M., Tan, Madeleine S. A., Thurecht, Kristofer J. and Falconer, James R. (2019). Preparation of albendazole-loaded liposomes by supercritical carbon dioxide processing. Artificial Cells, Nanomedicine, and Biotechnology, 46 (sup3), 1-7. doi: 10.1080/21691401.2018.1536059

Preparation of albendazole-loaded liposomes by supercritical carbon dioxide processing

2019

Journal Article

Importance of polymer length in fructose-based polymeric micelles for an enhanced biological activity

Lu, Mingxia, Chen, Fan, Cao, Cheng, Garvey, Christopher J., Fletcher, Nicholas L., Houston, Zachary H., Lu, Hongxu, Lord, Megan S., Thurecht, Kristofer J. and Stenzel, Martina H. (2019). Importance of polymer length in fructose-based polymeric micelles for an enhanced biological activity. Macromolecules, 52 (2) acs.macromol.8b02381, 477-486. doi: 10.1021/acs.macromol.8b02381

Importance of polymer length in fructose-based polymeric micelles for an enhanced biological activity

2018

Journal Article

RNA interference to enhance radiation therapy: targeting the DNA damage response

Ratnayake, G., Bain, A. L., Fletcher, N., Howard, C. B., Khanna, K. K. and Thurecht, K. J. (2018). RNA interference to enhance radiation therapy: targeting the DNA damage response. Cancer Letters, 439, 14-23. doi: 10.1016/j.canlet.2018.09.011

RNA interference to enhance radiation therapy: targeting the DNA damage response

2018

Journal Article

EphA3 pay-loaded antibody therapeutics for the treatment of glioblastoma

Offenhäuser, Carolin, Al-Ejeh, Fares, Puttick, Simon, Ensbey, Kathleen, Bruce, Zara, Jamieson, Paul, Smith, Fiona, Stringer, Brett, Carrington, Benjamin, Fuchs, Adrian, Bell, Craig, Jeffree, Rosalind, Rose, Stephen, Thurecht, Kristofer, Boyd, Andrew and Day, Bryan (2018). EphA3 pay-loaded antibody therapeutics for the treatment of glioblastoma. Cancers, 10 (12) 519, 519. doi: 10.3390/cancers10120519

EphA3 pay-loaded antibody therapeutics for the treatment of glioblastoma

2018

Journal Article

Dependence of block copolymer domain spacing and morphology on the cation structure of ionic liquid additives

Bennett, Thomas M., Chambers, Lewis C., Thurecht, Kristofer J., Jack, Kevin S. and Blakey, Idriss (2018). Dependence of block copolymer domain spacing and morphology on the cation structure of ionic liquid additives. Macromolecules, 51 (21) acs.macromol.8b01953, 8979-8986. doi: 10.1021/acs.macromol.8b01953

Dependence of block copolymer domain spacing and morphology on the cation structure of ionic liquid additives

2018

Journal Article

Minimum information reporting in bio–nano experimental literature

Faria, Matthew, Björnmalm, Mattias, Thurecht, Kristofer J., Kent, Stephen J., Parton, Robert G., Kavallaris, Maria, Johnston, Angus P. R., Gooding, J. Justin, Corrie, Simon R., Boyd, Ben J., Thordarson, Pall, Whittaker, Andrew K., Stevens, Molly M., Prestidge, Clive A., Porter, Christopher J. H., Parak, Wolfgang J., Davis, Thomas P., Crampin, Edmund J. and Caruso, Frank (2018). Minimum information reporting in bio–nano experimental literature. Nature Nanotechnology, 13 (9), 777-785. doi: 10.1038/s41565-018-0246-4

Minimum information reporting in bio–nano experimental literature

2018

Journal Article

Influence of Charge on Hemocompatibility and Immunoreactivity of Polymeric Nanoparticles

Chen, Liyu, Glass, Joshua J., De Rose, Robert, Sperling, Claudia, Kent, Stephen J., Houston, Zachary H., Fletcher, Nicholas L., Rolfe, Barbara E. and Thurecht, Kristofer J. (2018). Influence of Charge on Hemocompatibility and Immunoreactivity of Polymeric Nanoparticles. ACS Applied Bio Materials, 1 (3) acsabm.8b00220, 756-767. doi: 10.1021/acsabm.8b00220

Influence of Charge on Hemocompatibility and Immunoreactivity of Polymeric Nanoparticles

2018

Journal Article

In vivo therapeutic evaluation of polymeric nanomedicines: effect of different targeting peptides on therapeutic efficacy against breast cancer

Zhao, Yongmei, Fletcher, Nicholas L., Liu, Tianqing, Gemmell, Anna C., Houston, Zachary H., Blakey, Idriss and Thurecht, Kristofer J. (2018). In vivo therapeutic evaluation of polymeric nanomedicines: effect of different targeting peptides on therapeutic efficacy against breast cancer. Nanotheranostics, 2 (4), 360-370. doi: 10.7150/ntno.27142

In vivo therapeutic evaluation of polymeric nanomedicines: effect of different targeting peptides on therapeutic efficacy against breast cancer

2018

Journal Article

Confinement of therapeutic enzymes in selectively permeable polymer vesicles by Polymerization-Induced Self-Assembly (PISA) reduces antibody binding and proteolytic susceptibility

Blackman, Lewis D., Varlas, Spyridon, Arno, Maria C., Houston, Zachary H., Fletcher, Nicholas L., Thurecht, Kristofer J., Hasan, Muhammad, Gibson, Matthew I. and O’Reilly, Rachel K. (2018). Confinement of therapeutic enzymes in selectively permeable polymer vesicles by Polymerization-Induced Self-Assembly (PISA) reduces antibody binding and proteolytic susceptibility. ACS Central Science, 4 (6), 718-723. doi: 10.1021/acscentsci.8b00168

Confinement of therapeutic enzymes in selectively permeable polymer vesicles by Polymerization-Induced Self-Assembly (PISA) reduces antibody binding and proteolytic susceptibility

2018

Journal Article

Towards clinical translation of ligand-functionalized liposomes in targeted cancer therapy: challenges and opportunities

Belfiore, Lisa, Saunders, Darren N., Ranson, Marie, Thurecht, Kristofer J., Storm, Gert and Vine, Kara L. (2018). Towards clinical translation of ligand-functionalized liposomes in targeted cancer therapy: challenges and opportunities. Journal of Controlled Release, 277, 1-13. doi: 10.1016/j.jconrel.2018.02.040

Towards clinical translation of ligand-functionalized liposomes in targeted cancer therapy: challenges and opportunities

2018

Journal Article

Modified organosilica core-shell nanoparticles for stable pH sensing in biological solutions

Robinson, Kye J., Huynh, Gabriel T., Kouskousis, Betty P., Fletcher, Nicholas L., Houston, Zachary H., Thurecht, Kristofer J. and Corrie, Simon R. (2018). Modified organosilica core-shell nanoparticles for stable pH sensing in biological solutions. ACS Sensors, 3 (5), 967-975. doi: 10.1021/acssensors.8b00034

Modified organosilica core-shell nanoparticles for stable pH sensing in biological solutions

2018

Journal Article

Enhanced delivery of siRNA to triple negative breast cancer cells in vitro and in vivo through functionalizing lipid-coated calcium phosphate nanoparticles with dual target ligands

Tang, Jie, Howard, Christopher B., Mahler, Stephen M., Thurecht, Kristofer J., Huang, Leaf and Xu, Zhi Ping (2018). Enhanced delivery of siRNA to triple negative breast cancer cells in vitro and in vivo through functionalizing lipid-coated calcium phosphate nanoparticles with dual target ligands. Nanoscale, 10 (9), 4258-4266. doi: 10.1039/c7nr08644j

Enhanced delivery of siRNA to triple negative breast cancer cells in vitro and in vivo through functionalizing lipid-coated calcium phosphate nanoparticles with dual target ligands

2018

Journal Article

Bispecific antibody-functionalized upconversion nanoprobe

He, Hao, Howard, Christopher B., Chen, Yinghui, Wen, Shihui, Lin, Gungun, Zhou, Jiajia, Thurecht, Kristofer J. and Jin, Dayong (2018). Bispecific antibody-functionalized upconversion nanoprobe. Analytical Chemistry, 90 (5), 3024-3029. doi: 10.1021/acs.analchem.7b05341

Bispecific antibody-functionalized upconversion nanoprobe

2018

Journal Article

Designed multifunctional polymeric nanomedicines: long-term biodistribution and tumour accumulation of aptamer-targeted nanomaterials

Fletcher, N. L., Houston, Z. H., Simpson, J. D., Veedu, R. N. and Thurecht, K. J. (2018). Designed multifunctional polymeric nanomedicines: long-term biodistribution and tumour accumulation of aptamer-targeted nanomaterials. Chemical Communications, 54 (82), 11538-11541. doi: 10.1039/c8cc05831h

Designed multifunctional polymeric nanomedicines: long-term biodistribution and tumour accumulation of aptamer-targeted nanomaterials

2018

Journal Article

Recent advances in the generation of antibody-nanomaterial conjugates

Sivaram, Amal J, Wardiana, Andri, Howard, Christopher B, Mahler, Stephen M and Thurecht, Kristofer J (2018). Recent advances in the generation of antibody-nanomaterial conjugates. Advanced Healthcare Materials, 7 (1) 1700607. doi: 10.1002/adhm.201700607

Recent advances in the generation of antibody-nanomaterial conjugates

2017

Journal Article

Effects of Surface Charge of Hyperbranched Polymers on Cytotoxicity, Dynamic Cellular Uptake and Localization, Hemotoxicity, and Pharmacokinetics in Mice

Chen, Liyu, Simpson, Joshua D, Fuchs, Adrian V, Rolfe, Barbara E and Thurecht, Kristofer J (2017). Effects of Surface Charge of Hyperbranched Polymers on Cytotoxicity, Dynamic Cellular Uptake and Localization, Hemotoxicity, and Pharmacokinetics in Mice. Molecular pharmaceutics, 14 (12), 4485-4497. doi: 10.1021/acs.molpharmaceut.7b00611

Effects of Surface Charge of Hyperbranched Polymers on Cytotoxicity, Dynamic Cellular Uptake and Localization, Hemotoxicity, and Pharmacokinetics in Mice