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2021

Journal Article

Fluorophore selection and incorporation contribute to permeation and distribution behaviors of hyperbranched polymers in multi-cellular tumor spheroids and xenograft tumor models

Simpson, Joshua D., Monteiro, Patrícia F., Ediriweera, Gayathri R., Prior, Amber R., Sonderegger, Stefan E., Bell, Craig A., Fletcher, Nicholas L., Alexander, Cameron and Thurecht, Kristofer J. (2021). Fluorophore selection and incorporation contribute to permeation and distribution behaviors of hyperbranched polymers in multi-cellular tumor spheroids and xenograft tumor models. ACS Applied Bio Materials, 4 (3) acsabm.0c01616, 2675-2685. doi: 10.1021/acsabm.0c01616

Fluorophore selection and incorporation contribute to permeation and distribution behaviors of hyperbranched polymers in multi-cellular tumor spheroids and xenograft tumor models

2021

Journal Article

Characterization of the biodistribution of a silica vesicle Nanovaccine carrying a Rhipicephalus (Boophilus) microplus protective antigen with in vivo live animal imaging

Mody, Karishma T., Zhang, Bing, Li, Xun, Fletcher, Nicholas L., Akhter, Dewan T., Jarrett, Sandy, Zhang, Jun, Yu, Chengzhong, Thurecht, Kristofer J., Mahony, Timothy J and Mitter, Neena (2021). Characterization of the biodistribution of a silica vesicle Nanovaccine carrying a Rhipicephalus (Boophilus) microplus protective antigen with in vivo live animal imaging. Frontiers in Bioengineering and Biotechnology, 8 606652, 1-11. doi: 10.3389/fbioe.2020.606652

Characterization of the biodistribution of a silica vesicle Nanovaccine carrying a Rhipicephalus (Boophilus) microplus protective antigen with in vivo live animal imaging

2021

Journal Article

Curcumin chemoprevention reduces the incidence of Braf mutant colorectal cancer in a preclinical study

Kane, Alexandra M., Liu, Cheng, Akhter, Dewan T., McKeone, Diane M., Bell, Craig A., Thurecht, Kristofer J., Leggett, Barbara A. and Whitehall, Vicki L. J. (2021). Curcumin chemoprevention reduces the incidence of Braf mutant colorectal cancer in a preclinical study. Digestive Diseases and Sciences, 66 (12), 4326-4332. doi: 10.1007/s10620-020-06752-y

Curcumin chemoprevention reduces the incidence of Braf mutant colorectal cancer in a preclinical study

2021

Journal Article

Understanding the role of colon-specific microparticles based on retrograded starch/pectin in the delivery of chitosan nanoparticles along the gastrointestinal tract

dos Santos, Aline Martins, Meneguin, Andréia Bagliotti, Akhter, Dewan Taslima, Fletcher, Nicholas, Houston, Zachary H., Bell, Craig, Thurecht, Kristofer J. and Gremião, Maria Palmira Daflon (2021). Understanding the role of colon-specific microparticles based on retrograded starch/pectin in the delivery of chitosan nanoparticles along the gastrointestinal tract. European Journal of Pharmaceutics and Biopharmaceutics, 158, 371-378. doi: 10.1016/j.ejpb.2020.12.004

Understanding the role of colon-specific microparticles based on retrograded starch/pectin in the delivery of chitosan nanoparticles along the gastrointestinal tract

2020

Journal Article

Engineering fluorescent gold nanoclusters using xanthate-functionalized hydrophilic polymers: toward enhanced monodispersity and stability

Deepagan, Veerasikku Gopal, Leiske, Meike N., Fletcher, Nicholas L., Rudd, David, Tieu, Terence, Kirkwood, Nicholas, Thurecht, Kristofer J., Kempe, Kristian, Voelcker, Nicolas H. and Cifuentes-Rius, Anna (2020). Engineering fluorescent gold nanoclusters using xanthate-functionalized hydrophilic polymers: toward enhanced monodispersity and stability. Nano Letters, 21 (1) acs.nanolett.0c03930, 476-484. doi: 10.1021/acs.nanolett.0c03930

Engineering fluorescent gold nanoclusters using xanthate-functionalized hydrophilic polymers: toward enhanced monodispersity and stability

2020

Journal Article

A bispecific T cell engager targeting Glypican-1 redirects T cell cytolytic activity to kill prostate cancer cells

Lund, Maria E., Howard, Christopher B., Thurecht, Kristofer J., Campbell, Douglas H., Mahler, Stephen M. and Walsh, Bradley J. (2020). A bispecific T cell engager targeting Glypican-1 redirects T cell cytolytic activity to kill prostate cancer cells. BMC Cancer, 20 (1) 1214, 1214. doi: 10.1186/s12885-020-07562-1

A bispecific T cell engager targeting Glypican-1 redirects T cell cytolytic activity to kill prostate cancer cells

2020

Journal Article

The impact of polymer size and cleavability on the intravenous pharmacokinetics of PEG-based hyperbranched polymers in rats

Marasini, Nirmal, Fu, Changkui, Fletcher, Nicholas L., Subasic, Christopher, Er, Gerald, Mardon, Karine, Thurecht, Kristofer J., Whittaker, Andrew K. and Kaminskas, Lisa M. (2020). The impact of polymer size and cleavability on the intravenous pharmacokinetics of PEG-based hyperbranched polymers in rats. Nanomaterials, 10 (12) 2452, 1-16. doi: 10.3390/nano10122452

The impact of polymer size and cleavability on the intravenous pharmacokinetics of PEG-based hyperbranched polymers in rats

2020

Journal Article

Effect of chain‐end chemistries on the efficiency of coupling antibodies to polymers using unnatural amino acids

Sivaram, Amal J., Wardiana, Andri, Preethi, S. S. Hema, Fuchs, Adrian V., Howard, Christopher B., Fletcher, Nicholas L., Bell, Craig A. and Thurecht, Kristofer J. (2020). Effect of chain‐end chemistries on the efficiency of coupling antibodies to polymers using unnatural amino acids. Macromolecular Rapid Communications, 41 (21) 2000294, e2000294. doi: 10.1002/marc.202000294

Effect of chain‐end chemistries on the efficiency of coupling antibodies to polymers using unnatural amino acids

2020

Journal Article

Person-specific biomolecular coronas modulate nanoparticle interactions with immune cells in human blood

Ju, Yi, Kelly, Hannah G., Dagley, Laura F., Reynaldi, Arnold, Schlub, Timothy E., Spall, Sukhdeep K., Bell, Craig A., Cui, Jiwei, Mitchell, Andrew J., Lin, Zhixing, Wheatley, Adam K., Thurecht, Kristofer J., Davenport, Miles P., Webb, Andrew I., Caruso, Frank and Kent, Stephen J. (2020). Person-specific biomolecular coronas modulate nanoparticle interactions with immune cells in human blood. ACS Nano, 14 (11) acsnano.0c06679, 15723-15737. doi: 10.1021/acsnano.0c06679

Person-specific biomolecular coronas modulate nanoparticle interactions with immune cells in human blood

2020

Journal Article

Nanobody-displaying porous silicon nanoparticles for the co-delivery of siRNA and doxorubicin

Tieu, Terence, Wojnilowicz, Marcin, Huda, Pie, Thurecht, Kristofer J., Thissen, Helmut, Voelcker, Nicolas H. and Cifuentes-Rius, Anna (2020). Nanobody-displaying porous silicon nanoparticles for the co-delivery of siRNA and doxorubicin. Biomaterials Science, 9 (1), 133-147. doi: 10.1039/d0bm01335h

Nanobody-displaying porous silicon nanoparticles for the co-delivery of siRNA and doxorubicin

2020

Journal Article

Controlling the biological fate of micellar nanoparticles: balancing stealth and targeting

Sivaram, Amal J., Wardiana, Andri, Alcantara, Sheilajen, Sonderegger, Stefan E., Fletcher, Nicholas L., Houston, Zachary H., Howard, Christopher B., Mahler, Stephen M., Alexander, Cameron, Kent, Stephen J., Bell, Craig A. and Thurecht, Kristofer J. (2020). Controlling the biological fate of micellar nanoparticles: balancing stealth and targeting. ACS Nano, 14 (10) acsnano.0c06033, 13739-13753. doi: 10.1021/acsnano.0c06033

Controlling the biological fate of micellar nanoparticles: balancing stealth and targeting

2020

Journal Article

The Evolving Landscape of Polymer Science and Engineering in Australia

Kempe, Kristian and Thurecht, Kristofer J. (2020). The Evolving Landscape of Polymer Science and Engineering in Australia. Macromolecular Rapid Communications, 41 (18) 2000414, 1-2. doi: 10.1002/marc.202000414

The Evolving Landscape of Polymer Science and Engineering in Australia

2020

Journal Article

Stepwise like supramolecular polymerization of plasmonic nanoparticle building blocks through complementary interactions

Dey, Priyanka, Thurecht, Kristofer J., Fredericks, Peter M. and Blakey, Idriss (2020). Stepwise like supramolecular polymerization of plasmonic nanoparticle building blocks through complementary interactions. Macromolecules, 53 (17) acs.macromol.0c01149, 7469-7478. doi: 10.1021/acs.macromol.0c01149

Stepwise like supramolecular polymerization of plasmonic nanoparticle building blocks through complementary interactions

2020

Journal Article

Next‐generation polymeric nanomedicines for oncology: perspectives and future directions

Fletcher, Nicholas L., Kempe, Kristian and Thurecht, Kristofer J. (2020). Next‐generation polymeric nanomedicines for oncology: perspectives and future directions. Macromolecular Rapid Communications, 41 (18) 2000319, 2000319. doi: 10.1002/marc.202000319

Next‐generation polymeric nanomedicines for oncology: perspectives and future directions

2020

Journal Article

Hyperbranched Poly(2-oxazoline)s and Poly(ethylene glycol): A structure–activity comparison of biodistribution

Humphries, James, Pizzi, David, Sonderegger, Stefan E., Fletcher, Nicholas L., Houston, Zachary H., Bell, Craig A., Kempe, Kristian and Thurecht, Kristofer J. (2020). Hyperbranched Poly(2-oxazoline)s and Poly(ethylene glycol): A structure–activity comparison of biodistribution. Biomacromolecules, 21 (8) acs.biomac.0c00765, 3318-3331. doi: 10.1021/acs.biomac.0c00765

Hyperbranched Poly(2-oxazoline)s and Poly(ethylene glycol): A structure–activity comparison of biodistribution

2020

Journal Article

Surface polymer imprinted optical fibre sensor for dose detection of dabrafenib

He, Chenyang, Ledezma, Ulises Hernandez, Gurnani, Pratik, Albelha, Thais, Thurecht, Kristofer J., Correia, Ricardo, Morgan, Stephen P., Patel, Poulam, Alexander, Cameron and Korposh, Sergiy (2020). Surface polymer imprinted optical fibre sensor for dose detection of dabrafenib. Analyst, 145 (13), 4504-4511. doi: 10.1039/d0an00434k

Surface polymer imprinted optical fibre sensor for dose detection of dabrafenib

2020

Conference Publication

Canine PET/CT imaging with 64Cu-nanomedicines

Daniel, Sarah, Houston, Zachary, Fletcher, Nicholas, Bell, Craig, Atcheson, Nicole, Al-Najjar, Aiman, Howard, Christopher, Mahler, Stephen, Straw, Rod and Thurecht, Kristofer (2020). Canine PET/CT imaging with 64Cu-nanomedicines. SNMMI Annual Meeting, Online, 11-14 July, 2020. Reston, VA, United States: Society of Nuclear Medicine.

Canine PET/CT imaging with 64Cu-nanomedicines

2020

Journal Article

Understanding the uptake of nanomedicines at different stages of brain cancer using a modular nanocarrier platform and precision bispecific antibodies

Houston, Zachary H., Bunt, Jens, Chen, Kok-Siong, Puttick, Simon, Howard, Christopher B., Fletcher, Nicholas L., Fuchs, Adrian V., Cui, Jiwei, Ju, Yi, Cowin, Gary, Song, Xin, Boyd, Andrew W., Mahler, Stephen M., Richards, Linda J., Caruso, Frank and Thurecht, Kristofer J. (2020). Understanding the uptake of nanomedicines at different stages of brain cancer using a modular nanocarrier platform and precision bispecific antibodies. ACS Central Science, 6 (5) acscentsci.9b01299, 727-738. doi: 10.1021/acscentsci.9b01299

Understanding the uptake of nanomedicines at different stages of brain cancer using a modular nanocarrier platform and precision bispecific antibodies

2020

Journal Article

Direct comparison of poly(ethylene glycol) and phosphorylcholine drug-loaded nanoparticles in vitro and in vivo

Noy, Janina-Miriam, Chen, Fan, Akhter, Dewan T., Houston, Zachary H., Fletcher, Nicholas L., Thurecht, Kristofer J. and Stenzel, Martina H. (2020). Direct comparison of poly(ethylene glycol) and phosphorylcholine drug-loaded nanoparticles in vitro and in vivo. Biomacromolecules, 21 (6) acs.biomac.0c00257, 2320-2333. doi: 10.1021/acs.biomac.0c00257

Direct comparison of poly(ethylene glycol) and phosphorylcholine drug-loaded nanoparticles in vitro and in vivo

2020

Journal Article

Synthesis of biscarboxylic acid functionalised EDTA mimicking polymers and their ability to form Zr(iv) chelation mediated nanostructures

Leiske, Meike N., Walker, Julia A., Zia, Aadarash, Fletcher, Nicholas L., Thurecht, Kristofer J., Davis, Thomas P. and Kempe, Kristian (2020). Synthesis of biscarboxylic acid functionalised EDTA mimicking polymers and their ability to form Zr(iv) chelation mediated nanostructures. Polymer Chemistry, 11 (16), 2799-2810. doi: 10.1039/d0py00304b

Synthesis of biscarboxylic acid functionalised EDTA mimicking polymers and their ability to form Zr(iv) chelation mediated nanostructures