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2020

Journal Article

Investigation of the therapeutic potential of a synergistic delivery system through dual controlled release of camptothecin-doxorubicin

Zhao, Yongmei, Fletcher, Nicholas L., Gemmell, Anna, Houston, Zachary H., Howard, Christopher B., Blakey, Idriss, Liu, Tianqing and Thurecht, Kristofer J. (2020). Investigation of the therapeutic potential of a synergistic delivery system through dual controlled release of camptothecin-doxorubicin. Advanced Therapeutics, 3 (6) 1900202, 1900202. doi: 10.1002/adtp.201900202

Investigation of the therapeutic potential of a synergistic delivery system through dual controlled release of camptothecin-doxorubicin

2020

Journal Article

Oral delivery of multicompartment nanomedicines for colorectal cancer therapeutics: combining loco-regional delivery with cell-target specificity

Akhter, Dewan T., Simpson, Joshua D., Fletcher, Nicholas L., Houston, Zachary H., Fuchs, Adrian V., Bell, Craig A. and Thurecht, Kristofer J. (2020). Oral delivery of multicompartment nanomedicines for colorectal cancer therapeutics: combining loco-regional delivery with cell-target specificity. Advanced Therapeutics, 3 (2) 1900171, 1-13. doi: 10.1002/adtp.201900171

Oral delivery of multicompartment nanomedicines for colorectal cancer therapeutics: combining loco-regional delivery with cell-target specificity

2020

Journal Article

Targeted beta therapy of prostate cancer with 177Lu-labelled Miltuximab® antibody against glypican-1 (GPC-1)

Yeh, Mei-Chun, Tse, Brian W. C., Fletcher, Nicholas L., Houston, Zachary H., Lund, Maria, Volpert, Marianna, Stewart, Chelsea, Sokolowski, Kamil A., Jeet, Varinder, Thurecht, Kristofer J., Campbell, Douglas H., Walsh, Bradley J., Nelson, Colleen C. and Russell, Pamela J. (2020). Targeted beta therapy of prostate cancer with 177Lu-labelled Miltuximab® antibody against glypican-1 (GPC-1). EJNMMI Research, 10 (1) 46, 46. doi: 10.1186/s13550-020-00637-x

Targeted beta therapy of prostate cancer with 177Lu-labelled Miltuximab® antibody against glypican-1 (GPC-1)

2020

Journal Article

Targeted and modular architectural polymers employing bioorthogonal chemistry for quantitative therapeutic delivery

Ediriweera, Gayathri R., Simpson, Joshua D., Fuchs, Adrian V., Venkatachalam, Taracad K., Van De Walle, Matthias, Howard, Christopher B., Mahler, Stephen M., Blinco, James P., Fletcher, Nicholas L., Houston, Zachary H., Bell, Craig A. and Thurecht, Kristofer J. (2020). Targeted and modular architectural polymers employing bioorthogonal chemistry for quantitative therapeutic delivery. Chemical Science, 11 (12), 3268-3280. doi: 10.1039/d0sc00078g

Targeted and modular architectural polymers employing bioorthogonal chemistry for quantitative therapeutic delivery

2019

Journal Article

Poly(2-oxazoline) macromonomers as building blocks for functional and biocompatible polymer architectures

Pizzi, David, Humphries, James, Morrow, Joshua P., Fletcher, Nicholas L., Bell, Craig A., Thurecht, Kristofer J. and Kempe, Kristian (2019). Poly(2-oxazoline) macromonomers as building blocks for functional and biocompatible polymer architectures. European Polymer Journal, 121 109258, 109258. doi: 10.1016/j.eurpolymj.2019.109258

Poly(2-oxazoline) macromonomers as building blocks for functional and biocompatible polymer architectures

2019

Journal Article

Supramolecular fluorine magnetic resonance spectroscopy probe polymer based on Passerini bifunctional monomer

Couturaud, Benoit, Houston, Zachary H., Cowin, Gary J., Prokeš, Ivan, Foster, Jeffrey C., Thurecht, Kristofer J. and O'Reilly, Rachel K. (2019). Supramolecular fluorine magnetic resonance spectroscopy probe polymer based on Passerini bifunctional monomer. ACS Macro Letters, 8 (11), 1479-1483. doi: 10.1021/acsmacrolett.9b00626

Supramolecular fluorine magnetic resonance spectroscopy probe polymer based on Passerini bifunctional monomer

2019

Journal Article

Engineered polymeric materials for biological applications: overcoming challenges of the bio–nano interface

Simpson, Joshua D., Smith, Samuel A., Thurecht, Kristofer J. and Such, Georgina (2019). Engineered polymeric materials for biological applications: overcoming challenges of the bio–nano interface. Polymers, 11 (9) 1441, 1441. doi: 10.3390/polym11091441

Engineered polymeric materials for biological applications: overcoming challenges of the bio–nano interface

2019

Journal Article

Multifunctional lipid-coated calcium phosphate nanoplatforms for complete inhibition of large triple negative breast cancer via targeted combined therapy

Tang, Jie, Li, Bei, Howard, Christopher B., Mahler, Stephen M., Thurecht, Kristofer J., Wu, Yilun, Huang, Leaf and Xu, Zhi Ping (2019). Multifunctional lipid-coated calcium phosphate nanoplatforms for complete inhibition of large triple negative breast cancer via targeted combined therapy. Biomaterials, 216 119232, 119232. doi: 10.1016/j.biomaterials.2019.119232

Multifunctional lipid-coated calcium phosphate nanoplatforms for complete inhibition of large triple negative breast cancer via targeted combined therapy

2019

Journal Article

Polymer design and component selection contribute to uptake, distribution & trafficking behaviours of polyethylene glycol hyperbranched polymers in live MDA-MB-468 breast cancer cells

Simpson, Joshua D., Ediriweera, Gayathri R., Howard, Christopher B., Fletcher, Nicholas L., Bell, Craig A. and Thurecht, Kristofer J. (2019). Polymer design and component selection contribute to uptake, distribution & trafficking behaviours of polyethylene glycol hyperbranched polymers in live MDA-MB-468 breast cancer cells. Biomaterials Science, 7 (11), 4661-4674. doi: 10.1039/c9bm00957d

Polymer design and component selection contribute to uptake, distribution & trafficking behaviours of polyethylene glycol hyperbranched polymers in live MDA-MB-468 breast cancer cells

2019

Journal Article

Cellular targeting of bispecific antibody-functionalized poly(ethylene glycol) capsules: do shape and size matter?

Song, Danzi, Cui, Jiwei, Ju, Yi, Faria, Matthew, Sun, Huanli, Howard, Christopher B., Thurecht, Kristofer J. and Caruso, Frank (2019). Cellular targeting of bispecific antibody-functionalized poly(ethylene glycol) capsules: do shape and size matter?. ACS Applied Materials & Interfaces, 11 (32), 28720-28731. doi: 10.1021/acsami.9b10304

Cellular targeting of bispecific antibody-functionalized poly(ethylene glycol) capsules: do shape and size matter?

2019

Journal Article

Tagged Core-Satellite Nanoassemblies: Role of Assembling Sequence on Surface-Enhanced Raman Scattering (SERS) Performance

Dey, Priyanka, Thurecht, Kristofer J., Fredericks, Peter M. and Blakey, Idriss (2019). Tagged Core-Satellite Nanoassemblies: Role of Assembling Sequence on Surface-Enhanced Raman Scattering (SERS) Performance. Applied Spectroscopy, 73 (12), 000370281985666-1435. doi: 10.1177/0003702819856666

Tagged Core-Satellite Nanoassemblies: Role of Assembling Sequence on Surface-Enhanced Raman Scattering (SERS) Performance

2019

Journal Article

Dispersibility of phospholipids and their optimization for the efficient production of liposomes using supercritical fluid technology

Maqbool, Faheem, Moyle, Peter M., Thurecht, Kristofer J. and Falconer, James R. (2019). Dispersibility of phospholipids and their optimization for the efficient production of liposomes using supercritical fluid technology. International Journal of Pharmaceutics, 563, 174-183. doi: 10.1016/j.ijpharm.2019.03.053

Dispersibility of phospholipids and their optimization for the efficient production of liposomes using supercritical fluid technology

2019

Journal Article

Innovative therapeutic strategies for effective treatment of brain metastases

Lim, Malcolm, Puttick, Simon, Houston, Zachary H., Thurecht, Kristofer J., Kalita-de Croft, Priyakshi, Mahler, Stephen, Rose, Stephen E., Jeffree, Rosalind L., Mazzieri, Roberta, Dolcetti, Riccardo, Lakhani, Sunil R. and Saunus, Jodi M. (2019). Innovative therapeutic strategies for effective treatment of brain metastases. International Journal of Molecular Sciences, 20 (6) 1280, 1280. doi: 10.3390/ijms20061280

Innovative therapeutic strategies for effective treatment of brain metastases

2019

Journal Article

Modulating targeting of poly(ethylene glycol) particles to tumor cells using bispecific antibodies

Cui, Jiwei, Ju, Yi, Houston, Zachary H., Glass, Joshua J., Fletcher, Nicholas L., Alcantara, Sheilajen, Dai, Qiong, Howard, Christopher B., Mahler, Stephen M., Wheatley, Adam K., De Rose, Robert, Brannon, Paul T., Paterson, Brett M., Donnelly, Paul S., Thurecht, Kristofer J., Caruso, Frank and Kent, Stephen J. (2019). Modulating targeting of poly(ethylene glycol) particles to tumor cells using bispecific antibodies. Advanced Healthcare Materials, 8 (9) 1801607, e1801607. doi: 10.1002/adhm.201801607

Modulating targeting of poly(ethylene glycol) particles to tumor cells using bispecific antibodies

2019

Journal Article

Ultrasound-responsive nanobubbles for enhanced intravitreal drug migration: An ex vivo evaluation

Thakur, Sachin S., Chen, Ying-Shan, Houston, Zachary H., Fletcher, Nicholas, Barnett, Nigel L., Thurecht, Kristofer J., Rupenthal, Ilva D. and Parekh, Harendra S. (2019). Ultrasound-responsive nanobubbles for enhanced intravitreal drug migration: An ex vivo evaluation. European Journal of Pharmaceutics and Biopharmaceutics, 136, 102-107. doi: 10.1016/j.ejpb.2019.01.014

Ultrasound-responsive nanobubbles for enhanced intravitreal drug migration: An ex vivo evaluation

2019

Journal Article

Factorial design-assisted supercritical carbon-dioxide extraction of cytotoxic active principles from Carica papaya leaf juice

Khaw, Kooi-Yeong, Parat, Marie-Odile, Shaw, Paul Nicholas, Nguyen, Thao T. T., Pandey, Saurabh, Thurecht, Kristofer J. and Falconer, James Robert (2019). Factorial design-assisted supercritical carbon-dioxide extraction of cytotoxic active principles from Carica papaya leaf juice. Scientific Reports, 9 (1) 1716, 1716. doi: 10.1038/s41598-018-37171-9

Factorial design-assisted supercritical carbon-dioxide extraction of cytotoxic active principles from Carica papaya leaf juice

2019

Journal Article

Preparation of albendazole-loaded liposomes by supercritical carbon dioxide processing

Maqbool, Faheem, Moyle, Peter M., Tan, Madeleine S. A., Thurecht, Kristofer J. and Falconer, James R. (2019). Preparation of albendazole-loaded liposomes by supercritical carbon dioxide processing. Artificial Cells, Nanomedicine, and Biotechnology, 46 (sup3), 1-7. doi: 10.1080/21691401.2018.1536059

Preparation of albendazole-loaded liposomes by supercritical carbon dioxide processing

2019

Journal Article

Importance of polymer length in fructose-based polymeric micelles for an enhanced biological activity

Lu, Mingxia, Chen, Fan, Cao, Cheng, Garvey, Christopher J., Fletcher, Nicholas L., Houston, Zachary H., Lu, Hongxu, Lord, Megan S., Thurecht, Kristofer J. and Stenzel, Martina H. (2019). Importance of polymer length in fructose-based polymeric micelles for an enhanced biological activity. Macromolecules, 52 (2) acs.macromol.8b02381, 477-486. doi: 10.1021/acs.macromol.8b02381

Importance of polymer length in fructose-based polymeric micelles for an enhanced biological activity

2019

Conference Publication

Innovation in diagnosis and treatment of brain metastases using multifunctional nanomedicines

Saunus, J. M., Lim, M., Puttick, S., Croft, P. Kalita-de, Houston, Z. H., Jones, M. L., Latter, M. J., Campbell, L. C., Thomas, P., Jeffree, R. L., Rose, S. E., Mahler, S. M., Thurecht, K. J., Scott, A. M. and Lakhani, S. R. (2019). Innovation in diagnosis and treatment of brain metastases using multifunctional nanomedicines. San Antonio Breast Cancer Symposium, San Antonio, Texas, 4-8 December 2018. Philadelphia, PA, United States: American Association for Cancer Research. doi: 10.1158/1538-7445.SABCS18-P1-19-02

Innovation in diagnosis and treatment of brain metastases using multifunctional nanomedicines

2018

Journal Article

RNA interference to enhance radiation therapy: targeting the DNA damage response

Ratnayake, G., Bain, A. L., Fletcher, N., Howard, C. B., Khanna, K. K. and Thurecht, K. J. (2018). RNA interference to enhance radiation therapy: targeting the DNA damage response. Cancer Letters, 439, 14-23. doi: 10.1016/j.canlet.2018.09.011

RNA interference to enhance radiation therapy: targeting the DNA damage response