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2018

Journal Article

EphA3 pay-loaded antibody therapeutics for the treatment of glioblastoma

Offenhäuser, Carolin, Al-Ejeh, Fares, Puttick, Simon, Ensbey, Kathleen, Bruce, Zara, Jamieson, Paul, Smith, Fiona, Stringer, Brett, Carrington, Benjamin, Fuchs, Adrian, Bell, Craig, Jeffree, Rosalind, Rose, Stephen, Thurecht, Kristofer, Boyd, Andrew and Day, Bryan (2018). EphA3 pay-loaded antibody therapeutics for the treatment of glioblastoma. Cancers, 10 (12) 519, 519. doi: 10.3390/cancers10120519

EphA3 pay-loaded antibody therapeutics for the treatment of glioblastoma

2018

Journal Article

Dependence of block copolymer domain spacing and morphology on the cation structure of ionic liquid additives

Bennett, Thomas M., Chambers, Lewis C., Thurecht, Kristofer J., Jack, Kevin S. and Blakey, Idriss (2018). Dependence of block copolymer domain spacing and morphology on the cation structure of ionic liquid additives. Macromolecules, 51 (21) acs.macromol.8b01953, 8979-8986. doi: 10.1021/acs.macromol.8b01953

Dependence of block copolymer domain spacing and morphology on the cation structure of ionic liquid additives

2018

Journal Article

Minimum information reporting in bio–nano experimental literature

Faria, Matthew, Björnmalm, Mattias, Thurecht, Kristofer J., Kent, Stephen J., Parton, Robert G., Kavallaris, Maria, Johnston, Angus P. R., Gooding, J. Justin, Corrie, Simon R., Boyd, Ben J., Thordarson, Pall, Whittaker, Andrew K., Stevens, Molly M., Prestidge, Clive A., Porter, Christopher J. H., Parak, Wolfgang J., Davis, Thomas P., Crampin, Edmund J. and Caruso, Frank (2018). Minimum information reporting in bio–nano experimental literature. Nature Nanotechnology, 13 (9), 777-785. doi: 10.1038/s41565-018-0246-4

Minimum information reporting in bio–nano experimental literature

2018

Journal Article

Influence of Charge on Hemocompatibility and Immunoreactivity of Polymeric Nanoparticles

Chen, Liyu, Glass, Joshua J., De Rose, Robert, Sperling, Claudia, Kent, Stephen J., Houston, Zachary H., Fletcher, Nicholas L., Rolfe, Barbara E. and Thurecht, Kristofer J. (2018). Influence of Charge on Hemocompatibility and Immunoreactivity of Polymeric Nanoparticles. ACS Applied Bio Materials, 1 (3) acsabm.8b00220, 756-767. doi: 10.1021/acsabm.8b00220

Influence of Charge on Hemocompatibility and Immunoreactivity of Polymeric Nanoparticles

2018

Journal Article

In vivo therapeutic evaluation of polymeric nanomedicines: effect of different targeting peptides on therapeutic efficacy against breast cancer

Zhao, Yongmei, Fletcher, Nicholas L., Liu, Tianqing, Gemmell, Anna C., Houston, Zachary H., Blakey, Idriss and Thurecht, Kristofer J. (2018). In vivo therapeutic evaluation of polymeric nanomedicines: effect of different targeting peptides on therapeutic efficacy against breast cancer. Nanotheranostics, 2 (4), 360-370. doi: 10.7150/ntno.27142

In vivo therapeutic evaluation of polymeric nanomedicines: effect of different targeting peptides on therapeutic efficacy against breast cancer

2018

Conference Publication

Targeted beta therapy of human prostate cancer in vivo with Lu-177 labelled MIL-38 antibody against glypican-1 (GPC-1)

Yeh, Mei-Chun, Tse, Brian W. C., Fletcher, Nicholas L., Huston, Zachary H., Stewart, Chelsea, Sokolowski, Kamil, Jeet, Varinder, Wissmueller, Sandra, Thurecht, Kristofer J., Campbell, Douglas H., Walsh, Bradley J., Nelson, Colleen C. and Russell, Pamela J. (2018). Targeted beta therapy of human prostate cancer in vivo with Lu-177 labelled MIL-38 antibody against glypican-1 (GPC-1). 19th Asia-Pacific Prostate Cancer Conference, Brisbane Australia, Aug 22-25, 2018. HOBOKEN: WILEY.

Targeted beta therapy of human prostate cancer in vivo with Lu-177 labelled MIL-38 antibody against glypican-1 (GPC-1)

2018

Conference Publication

EPHA3 a novel tumour specific therapeutic target for medulloblastoma

Offenhauser, Carolin, Carrington, Benjamin, Thurecht, Kris, Ensbey, Kathleen, Bruce, Zara, Jamieson, Paul, Lim, Yi Chieh, Akgul, Seckin, Li, Michelle, Stringer, Brett, Puttick, Simon, Fuchs, Adrian, Picard, Daniel, Ingram, Wendy, Hallahan, Andrew, Moore, Andrew, Johns, Terrance, Gottardo, Nicholas, Remke, Marc, Boyd, Andrew and Day, Bryan (2018). EPHA3 a novel tumour specific therapeutic target for medulloblastoma. 18th International Symposium on Pediatric Neuro-Oncology (ISPNO), Denver, CO USA, 30 June-3 July 2018. Cary, NC USA: Oxford University Press.

EPHA3 a novel tumour specific therapeutic target for medulloblastoma

2018

Journal Article

Confinement of therapeutic enzymes in selectively permeable polymer vesicles by Polymerization-Induced Self-Assembly (PISA) reduces antibody binding and proteolytic susceptibility

Blackman, Lewis D., Varlas, Spyridon, Arno, Maria C., Houston, Zachary H., Fletcher, Nicholas L., Thurecht, Kristofer J., Hasan, Muhammad, Gibson, Matthew I. and O’Reilly, Rachel K. (2018). Confinement of therapeutic enzymes in selectively permeable polymer vesicles by Polymerization-Induced Self-Assembly (PISA) reduces antibody binding and proteolytic susceptibility. ACS Central Science, 4 (6), 718-723. doi: 10.1021/acscentsci.8b00168

Confinement of therapeutic enzymes in selectively permeable polymer vesicles by Polymerization-Induced Self-Assembly (PISA) reduces antibody binding and proteolytic susceptibility

2018

Journal Article

Towards clinical translation of ligand-functionalized liposomes in targeted cancer therapy: challenges and opportunities

Belfiore, Lisa, Saunders, Darren N., Ranson, Marie, Thurecht, Kristofer J., Storm, Gert and Vine, Kara L. (2018). Towards clinical translation of ligand-functionalized liposomes in targeted cancer therapy: challenges and opportunities. Journal of Controlled Release, 277, 1-13. doi: 10.1016/j.jconrel.2018.02.040

Towards clinical translation of ligand-functionalized liposomes in targeted cancer therapy: challenges and opportunities

2018

Journal Article

Modified organosilica core-shell nanoparticles for stable pH sensing in biological solutions

Robinson, Kye J., Huynh, Gabriel T., Kouskousis, Betty P., Fletcher, Nicholas L., Houston, Zachary H., Thurecht, Kristofer J. and Corrie, Simon R. (2018). Modified organosilica core-shell nanoparticles for stable pH sensing in biological solutions. ACS Sensors, 3 (5), 967-975. doi: 10.1021/acssensors.8b00034

Modified organosilica core-shell nanoparticles for stable pH sensing in biological solutions

2018

Journal Article

Enhanced delivery of siRNA to triple negative breast cancer cells in vitro and in vivo through functionalizing lipid-coated calcium phosphate nanoparticles with dual target ligands

Tang, Jie, Howard, Christopher B., Mahler, Stephen M., Thurecht, Kristofer J., Huang, Leaf and Xu, Zhi Ping (2018). Enhanced delivery of siRNA to triple negative breast cancer cells in vitro and in vivo through functionalizing lipid-coated calcium phosphate nanoparticles with dual target ligands. Nanoscale, 10 (9), 4258-4266. doi: 10.1039/c7nr08644j

Enhanced delivery of siRNA to triple negative breast cancer cells in vitro and in vivo through functionalizing lipid-coated calcium phosphate nanoparticles with dual target ligands

2018

Journal Article

Bispecific antibody-functionalized upconversion nanoprobe

He, Hao, Howard, Christopher B., Chen, Yinghui, Wen, Shihui, Lin, Gungun, Zhou, Jiajia, Thurecht, Kristofer J. and Jin, Dayong (2018). Bispecific antibody-functionalized upconversion nanoprobe. Analytical Chemistry, 90 (5), 3024-3029. doi: 10.1021/acs.analchem.7b05341

Bispecific antibody-functionalized upconversion nanoprobe

2018

Journal Article

Recent advances in the generation of antibody-nanomaterial conjugates

Sivaram, Amal J, Wardiana, Andri, Howard, Christopher B, Mahler, Stephen M and Thurecht, Kristofer J (2018). Recent advances in the generation of antibody-nanomaterial conjugates. Advanced Healthcare Materials, 7 (1) 1700607. doi: 10.1002/adhm.201700607

Recent advances in the generation of antibody-nanomaterial conjugates

2018

Journal Article

Designed multifunctional polymeric nanomedicines: long-term biodistribution and tumour accumulation of aptamer-targeted nanomaterials

Fletcher, N. L., Houston, Z. H., Simpson, J. D., Veedu, R. N. and Thurecht, K. J. (2018). Designed multifunctional polymeric nanomedicines: long-term biodistribution and tumour accumulation of aptamer-targeted nanomaterials. Chemical Communications, 54 (82), 11538-11541. doi: 10.1039/c8cc05831h

Designed multifunctional polymeric nanomedicines: long-term biodistribution and tumour accumulation of aptamer-targeted nanomaterials

2018

Conference Publication

Development of polymeric MRI agents as theranostics

Thurecht, Kristofer, Fuchs, Adrian, Bapat, Abhijeet and Houston, Zachary (2018). Development of polymeric MRI agents as theranostics. 255th National Meeting and Exposition of the American-Chemical-Society (ACS) - Nexus of Food, Energy, and Water, New Orleans, LA United States, 18-22 March 2018. Washington, DC United States: American Chemical Society.

Development of polymeric MRI agents as theranostics

2018

Conference Publication

Design-led 3D visualization of nanomedicines in virtual reality

Lilja, Andrew R., Strong, Campbell W., Bailey, Benjamin J., Thurecht, Kristofer J., Houston, Zachary H., Fletcher, Nicholas L. and McGhee, John B. (2018). Design-led 3D visualization of nanomedicines in virtual reality. 24th ACM Symposium on Virtual Reality Software and Technology (ACM VRST), Tokyo, Japan, Nov 28- Dec 01 2018. New York, NY, United States: Association for Computing Machinery. doi: 10.1145/3281505.3281572

Design-led 3D visualization of nanomedicines in virtual reality

2018

Book Chapter

Hyperbranched polymers as nanocarriers

Houston, Zachary H., Bell, Craig A. and Thurecht, Kristofer J. (2018). Hyperbranched polymers as nanocarriers. Encyclopedia of polymer science and technology. (pp. 1-27) Hoboken, NJ USA: John Wiley & Sons. doi: 10.1002/0471440264.pst159.pub2

Hyperbranched polymers as nanocarriers

2018

Conference Publication

Development of polymer theranostics to probe the behaviour of nanomaterials in biology

Thurecht, Kristofer, Zhou, Yongmei, Fletcher, Nicholas and Houston, Zachary (2018). Development of polymer theranostics to probe the behaviour of nanomaterials in biology. 255th National Meeting and Exposition of the American-Chemical-Society (ACS) - Nexus of Food, Energy, and Water, New Orleans, LA United States, 18-22 March 2018. Washington, DC United States: American Chemical Society.

Development of polymer theranostics to probe the behaviour of nanomaterials in biology

2017

Journal Article

Gold Nanocluster-Mediated Cellular Death under Electromagnetic Radiation

Cifuentes-Rius, Anna, Ivask, Angela, Das, Shreya, Penya-Auladell, Nuria, Fabregas, Laura, Fletcher, Nicholas L., Houston, Zachary H., Thurecht, Kristofer J. and Voelcker, Nicolas H. (2017). Gold Nanocluster-Mediated Cellular Death under Electromagnetic Radiation. Acs Applied Materials & Interfaces, 9 (47), 41159-41167. doi: 10.1021/acsami.7b13100

Gold Nanocluster-Mediated Cellular Death under Electromagnetic Radiation

2017

Journal Article

Effects of Surface Charge of Hyperbranched Polymers on Cytotoxicity, Dynamic Cellular Uptake and Localization, Hemotoxicity, and Pharmacokinetics in Mice

Chen, Liyu, Simpson, Joshua D, Fuchs, Adrian V, Rolfe, Barbara E and Thurecht, Kristofer J (2017). Effects of Surface Charge of Hyperbranched Polymers on Cytotoxicity, Dynamic Cellular Uptake and Localization, Hemotoxicity, and Pharmacokinetics in Mice. Molecular pharmaceutics, 14 (12), 4485-4497. doi: 10.1021/acs.molpharmaceut.7b00611

Effects of Surface Charge of Hyperbranched Polymers on Cytotoxicity, Dynamic Cellular Uptake and Localization, Hemotoxicity, and Pharmacokinetics in Mice