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2016

Journal Article

Nanoparticle-based medicines: a review of FDA-approved materials and clinical trials to date

Bobo, Daniel, Robinson, Kye J., Islam, Jiaul, Thurecht, Kristofer J. and Corrie, Simon R. (2016). Nanoparticle-based medicines: a review of FDA-approved materials and clinical trials to date. Pharmaceutical Research, 33 (10), 2373-2387. doi: 10.1007/s11095-016-1958-5

Nanoparticle-based medicines: a review of FDA-approved materials and clinical trials to date

2016

Journal Article

Targeted nanomaterials: overcoming instability of antibody-nanomaterial conjugates: next generation targeted nanomedicines using bispecific antibodies (Adv. Healthcare Mater. 16/2016)

Howard, Christopher B., Fletcher, Nicholas, Houston, Zachary H., Fuchs, Adrian V., Boase, Nathan R. B., Simpson, Joshua D., Raftery, Lyndon J., Ruder, Tim, Jones, Martina L., de Bakker, Christopher J., Mahler, Stephen M. and Thurecht, Kristofer J. (2016). Targeted nanomaterials: overcoming instability of antibody-nanomaterial conjugates: next generation targeted nanomedicines using bispecific antibodies (Adv. Healthcare Mater. 16/2016). Advanced Healthcare Materials, 5 (16), 1994-1994. doi: 10.1002/adhm.201670084

Targeted nanomaterials: overcoming instability of antibody-nanomaterial conjugates: next generation targeted nanomedicines using bispecific antibodies (Adv. Healthcare Mater. 16/2016)

2016

Journal Article

Bioerodable PLGA-based microparticles for producing sustained-release drug formulations and strategies for improving drug loading

Han, Felicity Y., Thurecht, Kristofer J., Whittaker, Andrew K. and Smith, Maree T. (2016). Bioerodable PLGA-based microparticles for producing sustained-release drug formulations and strategies for improving drug loading. Frontiers in Pharmacology, 7 (JUN) 185, 1-11. doi: 10.3389/fphar.2016.00185

Bioerodable PLGA-based microparticles for producing sustained-release drug formulations and strategies for improving drug loading

2016

Journal Article

Overcoming Instability of Antibody-Nanomaterial Conjugates: Next Generation Targeted Nanomedicines Using Bispecific Antibodies

Howard, Christopher B., Fletcher, Nicholas, Houston, Zachary H., Fuchs, Adrian V., Boase, Nathan R. B., Simpson, Joshua D., Raftery, Lyndon J., Ruder, Tim, Jones, Martina L., de Bakker, Christopher J., Mahler, Stephen M. and Thurecht, Kristofer J. (2016). Overcoming Instability of Antibody-Nanomaterial Conjugates: Next Generation Targeted Nanomedicines Using Bispecific Antibodies. Advanced Healthcare Materials, 5 (16), 2055-2068. doi: 10.1002/adhm.201600263

Overcoming Instability of Antibody-Nanomaterial Conjugates: Next Generation Targeted Nanomedicines Using Bispecific Antibodies

2016

Journal Article

Targeting Nanomedicines to Prostate Cancer: Evaluation of Specificity of Ligands to Two Different Receptors In Vivo

Pearce, Amanda K., Fuchs, Adrian V., Fletcher, Nicholas L. and Thurecht, Kristofer J. (2016). Targeting Nanomedicines to Prostate Cancer: Evaluation of Specificity of Ligands to Two Different Receptors In Vivo. Pharmaceutical Research, 33 (10), 1-12. doi: 10.1007/s11095-016-1945-x

Targeting Nanomedicines to Prostate Cancer: Evaluation of Specificity of Ligands to Two Different Receptors In Vivo

2016

Journal Article

Fluorinated POSS-star polymers for 19F MRI

Wang, Kewei, Peng, Hui, Thurecht, Kristofer J. and Whittaker, Andrew K. (2016). Fluorinated POSS-star polymers for 19F MRI. Macromolecular Chemistry and Physics, 217 (20), 2262-2274. doi: 10.1002/macp.201600084

Fluorinated POSS-star polymers for 19F MRI

2016

Journal Article

Biosensing made easy with PEG-targeted bi-specific antibodies

Raftery, Lyndon J., Grewal, Yadveer S., Howard, Christopher B., Jones, Martina L., Shiddiky, Muhammad J. A., Carrascosa, Laura G., Thurecht, Kristofer J., Mahler, Stephen M. and Trau, Matt (2016). Biosensing made easy with PEG-targeted bi-specific antibodies. Chemical Communications, 52 (33), 5730-5733. doi: 10.1039/C6CC01916A

Biosensing made easy with PEG-targeted bi-specific antibodies

2016

Journal Article

Synthesis, characterization and biological activities of semicarbazones and their copper complexes

Venkatachalam, Taracad K., Bernhardt, Paul V., Noble, Chris J., Fletcher, Nicholas, Pierens, Gregory K., Thurecht, Kris J. and Reutens, David C. (2016). Synthesis, characterization and biological activities of semicarbazones and their copper complexes. Journal of Inorganic Biochemistry, 162, 295-308. doi: 10.1016/j.jinorgbio.2016.04.006

Synthesis, characterization and biological activities of semicarbazones and their copper complexes

2016

Journal Article

Synthesis of 19F nucleic acid-polymer conjugates as real-time MRI probes of biorecognition

Sicilia, Giovanna, Davis, Adrienne L., Spain, Sebastian G., Magnusson, Johannes P., Boase, Nathan R. B., Thurecht, Kristofer J. and Alexander, Cameron (2016). Synthesis of 19F nucleic acid-polymer conjugates as real-time MRI probes of biorecognition. Polymer Chemistry, 7 (12), 2180-2191. doi: 10.1039/c5py01883h

Synthesis of 19F nucleic acid-polymer conjugates as real-time MRI probes of biorecognition

2016

Journal Article

Perturbation of the experimental phase diagram of a diblock copolymer by blending with an ionic liquid

Bennett, Thomas M., Jack, Kevin S., Thurecht, Kristofer J. and Blakey, Idriss (2016). Perturbation of the experimental phase diagram of a diblock copolymer by blending with an ionic liquid. Macromolecules, 49 (1), 205-214. doi: 10.1021/acs.macromol.5b02041

Perturbation of the experimental phase diagram of a diblock copolymer by blending with an ionic liquid

2016

Conference Publication

MILGa-01-a first in human study assessing the safety and tolerability of chMIL-38 in prostate cancer

Sabanathan, Dhanusha, Gurney, Howard, Gillatt, David, Trifunovic, Marko, Magnussen, John, Poursoultan, Pirooz, Shon, Kevin H. O., Walsh, Bradley J., Mazure, Hubert, Velonas, Vicki, Thurecht, Kris, Quach Truong, Wissmueller, Sandra and Campbell, Douglas (2016). MILGa-01-a first in human study assessing the safety and tolerability of chMIL-38 in prostate cancer. 17th Asia-Pacific Prostate Cancer Conference, Melbourne Australia, August 31 - September 3 2016. United Kingdom: Wiley-Blackwell.

MILGa-01-a first in human study assessing the safety and tolerability of chMIL-38 in prostate cancer

2016

Journal Article

Spectral normalisation by error minimisation for prediction of conversion in solvent-free catalytic chain transfer polymerisations

Richardson, Samuel J., Blakey, Idriss, Thurecht, Kristofer J., Irvine, Derek J. and Whittaker, Andrew K. (2016). Spectral normalisation by error minimisation for prediction of conversion in solvent-free catalytic chain transfer polymerisations. RSC Advances, 6 (73), 69484-69491. doi: 10.1039/c6ra06462k

Spectral normalisation by error minimisation for prediction of conversion in solvent-free catalytic chain transfer polymerisations

2016

Conference Publication

EphA receptor tyrosine kinases as targets for therapy in paediatric medulloblastoma

Carrington, Benjamin, Al-Ejeh, Fares, Lim, Yi Chieh, Ensbey, Kathleen, Bruce, Zara, Jamieson, Paul, Fuchs, Adrian, Thurecht, Kristofer, Stringer, Brett, Boyd, Andrew and Day, Bryan (2016). EphA receptor tyrosine kinases as targets for therapy in paediatric medulloblastoma. 21st Annual Scientific Meeting and Education Day of the Society-for-Neuro-Oncology, Scottsdale, AZ, United States, 17-20 November 2016. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/neuonc/now212.638

EphA receptor tyrosine kinases as targets for therapy in paediatric medulloblastoma

2016

Conference Publication

Evaluation of the in vivo fate of ultrapure alginate in mice model

Anitha, A., Fletcher, Nicholas, Houston, Zachary, Thurecht, Kristofer and Grondahl, Lisbeth (2016). Evaluation of the in vivo fate of ultrapure alginate in mice model. 10th World Biomaterials Congress, Montréal, Canada, 17 May - 22 May 2016. Lausanne, Switzerland: Frontiers Research Foundation. doi: 10.3389/conf.FBIOE.2016.01.02237

Evaluation of the in vivo fate of ultrapure alginate in mice model

2016

Journal Article

Multifunctional hyperbranched polymers for CT/19F MRI bimodal molecular imaging

Wang, Kewei, Peng, Hui, Thurecht, Kristofer J., Puttick, Simon and Whittaker, Andrew K. (2016). Multifunctional hyperbranched polymers for CT/19F MRI bimodal molecular imaging. Polymer Chemistry, 7 (5), 1059-1069. doi: 10.1039/c5py01707f

Multifunctional hyperbranched polymers for CT/19F MRI bimodal molecular imaging

2016

Conference Publication

Targeted multimodal hyperbranched polymers for imaging and therapy of prostate cancer

Tse, Brian W-C, Pearce, Amanda, Fuchs, Adrian V., Simpson, Joshua D., Yeh, Mei-Chun, Huang, Steve S., Heston, Warren D. W., Williams, Elizabeth D., Whittaker, Andrew K., Thurecht, Kristofer J. and Russell, Pamela J. (2016). Targeted multimodal hyperbranched polymers for imaging and therapy of prostate cancer. 17th Asia-Pacific Prostate Cancer Conference, Melbourne Australia, August 31-September 3 2016. United Kingdom: Wiley-Blackwell.

Targeted multimodal hyperbranched polymers for imaging and therapy of prostate cancer

2016

Book Chapter

Molecular imaging utilizing aptamer-targeted probes

Fletcher, Nicholas and Thurechta, Kristofer (2016). Molecular imaging utilizing aptamer-targeted probes. Aptamers: tools for nanotherapy and molecular imaging. (pp. 287-317) edited by Rakesh N. Veedu. Singapore: Pan Stanford Publishing. doi: 10.1201/b20047-11

Molecular imaging utilizing aptamer-targeted probes

2015

Journal Article

Comparison between polyethylene glycol and zwitterionic polymers as antifouling coatings on wearable devices for selective antigen capture from biological tissue

Robinson, Kye J., Coffey, Jacob W., Muller, David A., Young, Paul R., Kendall, Mark A., Thurecht, Kristofer J., Grøndahl, Lisbeth and Corrie, Simon R. (2015). Comparison between polyethylene glycol and zwitterionic polymers as antifouling coatings on wearable devices for selective antigen capture from biological tissue. Biointerphases, 10 (4) 04A305, 04A305.1-04A305.11. doi: 10.1116/1.4932055

Comparison between polyethylene glycol and zwitterionic polymers as antifouling coatings on wearable devices for selective antigen capture from biological tissue

2015

Journal Article

Evaluation of polymeric nanomedicines targeted to PSMA: effect of ligand on targeting efficiency

Fuchs, Adrian V., Tse, Brian W.C., Pearce, Amanda. K., Yeh, Mei-Chun, Fletcher, Nicholas L., Huang, Steve S., Heston, Warren D., Whittaker, Andrew K., Russell, Pamela J. and Thurecht, Kristofer J. (2015). Evaluation of polymeric nanomedicines targeted to PSMA: effect of ligand on targeting efficiency. Biomacromolecules, 16 (10), 3235-3247. doi: 10.1021/acs.biomac.5b00913

Evaluation of polymeric nanomedicines targeted to PSMA: effect of ligand on targeting efficiency

2015

Journal Article

The in vivo fate of nanoparticles and nanoparticle-loaded microcapsules after oral administration in mice: evaluation of their potential for colon-specific delivery

Ma, Yiming, Fuchs, Adrian V., Boase, Nathan R. B., Rolfe, Barbara E., Coombes, Allan G. A. and Thurecht, Kristofer J. (2015). The in vivo fate of nanoparticles and nanoparticle-loaded microcapsules after oral administration in mice: evaluation of their potential for colon-specific delivery. European Journal of Pharmaceutics and Biopharmaceutics, 94, 393-403. doi: 10.1016/j.ejpb.2015.06.014

The in vivo fate of nanoparticles and nanoparticle-loaded microcapsules after oral administration in mice: evaluation of their potential for colon-specific delivery