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2018

Journal Article

Pain-causing venom peptides: insights into sensory neuron pharmacology

Jami, Sina, Erickson, Andelain, Brierley, Stuart M and Vetter, Irina (2018). Pain-causing venom peptides: insights into sensory neuron pharmacology. Toxins, 10 (1) 15, 15. doi: 10.3390/toxins10010015

Pain-causing venom peptides: insights into sensory neuron pharmacology

2017

Journal Article

Subtle modifications to oxytocin produce ligands that retain potency and improved selectivity across species

Muttenthaler, Markus, Andersson, Asa, Vetter, Irina, Menon, Rohit, Busnelli, Marta, Ragnarsson, Lotten, Bergmayr, Christian, Arrowsmith, Sarah, Deuis, Jennifer R., Chiu, Han Sheng, Palpant, Nathan J., O'Brien, Margaret, Smith, Terry J., Wray, Susan, Neumann, Inga D., Gruber, Christian W., Lewis, Richard J. and Alewood, Paul F. (2017). Subtle modifications to oxytocin produce ligands that retain potency and improved selectivity across species. Science Signaling, 10 (508) eaan3398, 1-13. doi: 10.1126/scisignal.aan3398

Subtle modifications to oxytocin produce ligands that retain potency and improved selectivity across species

2017

Journal Article

Conotoxin Φ-MiXXVIIA from the superfamily G2 employs a novel cysteine framework that mimics granulin and displays anti-apoptotic activity

Jin, Ai-Hua, Dekan, Zoltan, Smout, Michael J., Wilson, David, Dutertre, Sébastien, Vetter, Irina, Lewis, Richard J., Loukas, Alex, Daly, Norelle L. and Alewood, Paul F. (2017). Conotoxin Φ-MiXXVIIA from the superfamily G2 employs a novel cysteine framework that mimics granulin and displays anti-apoptotic activity. Angewandte Chemie, 129 (47), 15169-15172. doi: 10.1002/ange.201708927

Conotoxin Φ-MiXXVIIA from the superfamily G2 employs a novel cysteine framework that mimics granulin and displays anti-apoptotic activity

2017

Journal Article

Toxins in neurobiology: new tools from old molecules

Vetter, Irina (2017). Toxins in neurobiology: new tools from old molecules. Neuroscience Letters, 679, 1-3. doi: 10.1016/j.neulet.2017.11.002

Toxins in neurobiology: new tools from old molecules

2017

Journal Article

Conotoxin Φ-MiXXVIIA from the Superfamily G2 Employs a Novel Cysteine Framework that Mimics Granulin and Displays Anti-Apoptotic Activity

Jin, Ai-Hua, Dekan, Zoltan, Smout, Michael J., Wilson, David, Dutertre, Sébastien, Vetter, Irina, Lewis, Richard J., Loukas, Alex, Daly, Norelle L. and Alewood, Paul F. (2017). Conotoxin Φ-MiXXVIIA from the Superfamily G2 Employs a Novel Cysteine Framework that Mimics Granulin and Displays Anti-Apoptotic Activity. Angewandte Chemie (International ed. in English), 56 (47), 14973-14976. doi: 10.1002/anie.201708927

Conotoxin Φ-MiXXVIIA from the Superfamily G2 Employs a Novel Cysteine Framework that Mimics Granulin and Displays Anti-Apoptotic Activity

2017

Journal Article

Burn pain: a systematic and critical review of epidemiology, pathophysiology, and treatment

Morgan, Michael, Deuis, Jennifer R., Frøsig-Jørgensen, Majbrit, Lewis, Richard J., Cabot, Peter J., Gray, Paul D. and Vetter, Irina (2017). Burn pain: a systematic and critical review of epidemiology, pathophysiology, and treatment. Pain Medicine, 19 (4), 708-734. doi: 10.1093/pm/pnx228

Burn pain: a systematic and critical review of epidemiology, pathophysiology, and treatment

2017

Journal Article

Discovery and mode of action of a novel analgesic β-toxin from the African spider Ceratogyrus darlingi

Sousa, Silmara R., Wingerd, Joshua S., Brust, Andreas, Bladen, Christopher, Ragnarsson, Lotten, Herzig, Volker, Deuis, Jennifer R., Dutertre, Sebastien, Vetter, Irina, Zamponi, Gerald W., King, Glenn F., Alewood, Paul F. and Lewis, Richard J. (2017). Discovery and mode of action of a novel analgesic β-toxin from the African spider Ceratogyrus darlingi. PLoS One, 12 (9) e0182848, e0182848. doi: 10.1371/journal.pone.0182848

Discovery and mode of action of a novel analgesic β-toxin from the African spider Ceratogyrus darlingi

2017

Journal Article

Methods used to evaluate pain behaviors in rodents

Deuis, Jennifer R., Dvorakova, Lucie S. and Vetter, Irina (2017). Methods used to evaluate pain behaviors in rodents. Frontiers in Molecular Neuroscience, 10 284, 284. doi: 10.3389/fnmol.2017.00284

Methods used to evaluate pain behaviors in rodents

2017

Journal Article

Optimization and in vivo profiling of a refined rat model of Walker 256 breast cancer cell-induced bone pain using behavioral, radiological, histological, immunohistochemical and pharmacological methods

Shenoy, Priyank, Kuo, Andy, Vetter, Irina and Smith, Maree T. (2017). Optimization and in vivo profiling of a refined rat model of Walker 256 breast cancer cell-induced bone pain using behavioral, radiological, histological, immunohistochemical and pharmacological methods. Frontiers in Pharmacology, 8 (JUL) 442, 442. doi: 10.3389/fphar.2017.00442

Optimization and in vivo profiling of a refined rat model of Walker 256 breast cancer cell-induced bone pain using behavioral, radiological, histological, immunohistochemical and pharmacological methods

2017

Journal Article

Δ-Myrtoxin-Mp1a is a helical heterodimer from the venom of the jack jumper ant that has antimicrobial, membrane-disrupting, and nociceptive activities

Dekan, Zoltan, Headey, Stephen J., Scanlon, Martin, Baldo, Brian A., Lee, Tzong-Hsien, Aguilar, Marie-Isabel, Deuis, Jennifer R., Vetter, Irina, Elliott, Alysha G., Amado, Maite, Cooper, Matthew A., Alewood, Dianne and Alewood, Paul F. (2017). Δ-Myrtoxin-Mp1a is a helical heterodimer from the venom of the jack jumper ant that has antimicrobial, membrane-disrupting, and nociceptive activities. Angewandte Chemie, 56 (29), 8495-8499. doi: 10.1002/anie.201703360

Δ-Myrtoxin-Mp1a is a helical heterodimer from the venom of the jack jumper ant that has antimicrobial, membrane-disrupting, and nociceptive activities

2017

Journal Article

Pathophysiology of chemotherapy-induced peripheral neuropathy

Starobova, Hana and Vetter, Irina (2017). Pathophysiology of chemotherapy-induced peripheral neuropathy. Frontiers in Molecular Neuroscience, 10 174. doi: 10.3389/fnmol.2017.00174

Pathophysiology of chemotherapy-induced peripheral neuropathy

2017

Journal Article

Corrigendum: Pharmacological characterisation of the highly Na v 1.7 selective spider venom peptide Pn3a (Scientific Reports (2017) 7 (40883)

Deuis, Jennifer R., Dekan, Zoltan, Wingerd, Joshua S., Smith, Jennifer J., Munasinghe, Nehan R., Bhola, Rebecca F., Imlach, Wendy L., Herzig, Volker, Armstrong, David A., Rosengren, K. Johan, Bosmans, Frank, Waxman, Stephen G., Dib-Hajj, Sulayman D., Escoubas, Pierre, Minett, Michael S., Christie, Macdonald J., King, Glenn F., Alewood, Paul F., Lewis, Richard J., Wood, John N. and Vetter, Irina (2017). Corrigendum: Pharmacological characterisation of the highly Na v 1.7 selective spider venom peptide Pn3a (Scientific Reports (2017) 7 (40883). Scientific Reports, 7 (1) 46816, 46816. doi: 10.1038/srep46816

Corrigendum: Pharmacological characterisation of the highly Na v 1.7 selective spider venom peptide Pn3a (Scientific Reports (2017) 7 (40883)

2017

Journal Article

Modulatory features of the novel spider toxin μ-TRTX-Df1a isolated from the venom of the spider Davus fasciatus

Cardoso, Fernanda Caldas, Dekan, Zoltan, Smith, Jennifer J., Deuis, Jennifer R., Vetter, Irina, Herzig, Volker, Alewood, Paul F., King, Glenn F and Lewis, Richard J. (2017). Modulatory features of the novel spider toxin μ-TRTX-Df1a isolated from the venom of the spider Davus fasciatus. British Journal of Pharmacology, 174 (15), 2528-2544. doi: 10.1111/bph.13865

Modulatory features of the novel spider toxin μ-TRTX-Df1a isolated from the venom of the spider Davus fasciatus

2017

Journal Article

The Evolution of Fangs, Venom, and Mimicry Systems in Blenny Fishes (vol 27, pg 1184, 2017)

Casewell, Nicholas R., Visser, Jeroen C., Baumann, Kate, Dobson, James, Han, Han, Kuruppu, Sanjaya, Morgan, Michael, Romilio, Anthony, Weisbecker, Vera, Mardon, Karine, Ali, Syed A., Debono, Jordan, Koludarov, Ivan, Que, Ivo, Bird, Gregory C., Cooke, Gavan M., Nouwens, Amanda, Hodgson, Wayne C., Wagstaff, Simon C., Cheney, Karen L., Vetter, Irina, van der Weerd, Louise, Richardson, Michael K. and Fry, Bryan G. (2017). The Evolution of Fangs, Venom, and Mimicry Systems in Blenny Fishes (vol 27, pg 1184, 2017). Current Biology, 27 (10), 1549-1550. doi: 10.1016/j.cub.2017.05.009

The Evolution of Fangs, Venom, and Mimicry Systems in Blenny Fishes (vol 27, pg 1184, 2017)

2017

Journal Article

The pharmacology of voltage-gated sodium channel activators

Deuis, Jennifer R., Mueller, Alexander, Israel, Mathilde R. and Vetter, Irina (2017). The pharmacology of voltage-gated sodium channel activators. Neuropharmacology, 127, 87-108. doi: 10.1016/j.neuropharm.2017.04.014

The pharmacology of voltage-gated sodium channel activators

2017

Journal Article

Lethal effects of an insecticidal spider venom peptide involve positive allosteric modulation of insect nicotinic acetylcholine receptors

Windley, Monique J., Vetter, Irina, Lewis, Richard J. and Nicholson, Graham M. (2017). Lethal effects of an insecticidal spider venom peptide involve positive allosteric modulation of insect nicotinic acetylcholine receptors. Neuropharmacology, 127, 224-242. doi: 10.1016/j.neuropharm.2017.04.008

Lethal effects of an insecticidal spider venom peptide involve positive allosteric modulation of insect nicotinic acetylcholine receptors

2017

Journal Article

Sodium Channels and Venom Peptide Pharmacology

Israel, Mathilde R., Tay, Bryan, Deuis, Jennifer R. and Vetter, Irina (2017). Sodium Channels and Venom Peptide Pharmacology. Advances in Pharmacology, 79, 67-116. doi: 10.1016/bs.apha.2017.01.004

Sodium Channels and Venom Peptide Pharmacology

2017

Journal Article

Pharmacological screening technologies for venom peptide discovery

Prashanth, Jutty Rajan, Hasaballah, Nojod and Vetter, Irina (2017). Pharmacological screening technologies for venom peptide discovery. Neuropharmacology, 127, 4-19. doi: 10.1016/j.neuropharm.2017.03.038

Pharmacological screening technologies for venom peptide discovery

2017

Journal Article

The evolution of fangs, venom, and mimicry systems in blenny fishes

Casewell, Nicholas R., Visser, Jeroen C., Baumann, Kate, Dobson, James, Han, Han, Kuruppu, Sanjaya, Morgan, Michael, Romilio, Anthony, Weisbecker, Vera, Ali, Syed A., Debono, Jordan, Koludarov, Ivan, Que, Ivo, Bird, Gregory C., Cooke, Gavan M., Nouwens, Amanda, Hodgson, Wayne C., Wagstaff, Simon C., Cheney, Karen L., Vetter, Irina, van der Weerd, Louise, Richardson, Michael K. and Fry, Bryan G. (2017). The evolution of fangs, venom, and mimicry systems in blenny fishes. Current Biology, 27 (8), 1184-1191. doi: 10.1016/j.cub.2017.02.067

The evolution of fangs, venom, and mimicry systems in blenny fishes

2017

Journal Article

The structure, dynamics and selectivity profile of a NaV 1.7 potency-optimised huwentoxin-IV variant

Rahnama, Sassan, Deuis, Jennifer R., Cardoso, Fernanda C., Ramanujam, Venkatraman, Lewis, Richard J., Rash, Lachlan D., King, Glenn F., Vetter, Irina and Mobli, Mehdi (2017). The structure, dynamics and selectivity profile of a NaV 1.7 potency-optimised huwentoxin-IV variant. PLoS One, 12 (3) e0173551, e0173551. doi: 10.1371/journal.pone.0173551

The structure, dynamics and selectivity profile of a NaV 1.7 potency-optimised huwentoxin-IV variant