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2024

Conference Publication

Impact on chemotherapy induced peripheral neuropathy of nadunolimab, a first-in-class monoclonal antibody against IL1RAP, in patients with pancreatic cancer, with supportive mouse model data

Van Cutsem, Eric, Ochsenreither, Sebastian, Collignon, Joelle, Eefsen, Rikke Løvendahl, Ivanauskas, Audrius, Shatunova, Svetlana, Vetter, Irina, Gyllenbäck, Elin Jaensson, Skoog, Petter, Losic, Nedjad, Tersago, Dominique and Starobova, Hana (2024). Impact on chemotherapy induced peripheral neuropathy of nadunolimab, a first-in-class monoclonal antibody against IL1RAP, in patients with pancreatic cancer, with supportive mouse model data. 2024 ASCO Annual Meeting, Chicago, IL United States, 31 May - 4 June 2024. Alexandria, VA United States: American Society of Clinical Oncology. doi: 10.1200/jco.2024.42.16_suppl.4148

Impact on chemotherapy induced peripheral neuropathy of nadunolimab, a first-in-class monoclonal antibody against IL1RAP, in patients with pancreatic cancer, with supportive mouse model data

2024

Conference Publication

Impact on chemotherapy induced peripheral neuropathy of nadunolimab, a first-in-class monoclonal antibody against IL1RAP, in patients with pancreatic cancer, with supportive mouse model data

Van Cutsem, Eric, Ochsenreither, Sebastian, Collignon, Joelle, Eefsen, Rikke Lovendahl, Ivanauskas, Audrius, Shatunova, Svetlana, Vetter, Irina, Gyllenback, Elin Jaensson, Skoog, Petter, Losic, Nedjad, Tersago, Dominique and Starobova, Hana (2024). Impact on chemotherapy induced peripheral neuropathy of nadunolimab, a first-in-class monoclonal antibody against IL1RAP, in patients with pancreatic cancer, with supportive mouse model data. 2024 ASCO Annual Meeting Gastrointestinal Cancer—Gastroesophageal, Pancreatic, and Hepatobiliary, Chicago, IL, United States, 31 May - 4 June 2024. Alexandria, VA, United States: American Society of Clinical Oncology.

Impact on chemotherapy induced peripheral neuropathy of nadunolimab, a first-in-class monoclonal antibody against IL1RAP, in patients with pancreatic cancer, with supportive mouse model data

2021

Conference Publication

Subcutaneous analgesic actions and mode of action of binding of ω-conotoxins at Cav2.2

Hasan, Mahadhi, Abraham, Nikita, Cardoso, Fernanda C., Ragnarsson, Lotten, Starobova, Hana, Mueller, Alexander, Vetter, Irina and Lewis, Richard J. (2021). Subcutaneous analgesic actions and mode of action of binding of ω-conotoxins at Cav2.2. Venom to Drugs, Daydream Island, QLD Australia, 15 - 19 March 2021.

Subcutaneous analgesic actions and mode of action of binding of ω-conotoxins at Cav2.2

2020

Conference Publication

Convergent evolution of defensive venom components in spitting cobras

Kazandjian, Taline, Petras, Daniel, Robinson, Sam, Undheim, Eivind, Arbuckle, Kevin, Whiteley, Gareth, Albulescu, Laura-Oana, Ainsworth, Stuart, Wagstaff, Simon, Wuster, Wolfgang, Harrison, Robert, Vetter, Irina, Calvete, Juan and Casewell, Nicholas (2020). Convergent evolution of defensive venom components in spitting cobras. 20th World Congress of the International Society on Toxinology, Buenos Aires, Argentina, 8-13 September 2019. Oxford, United Kingdom: Elsevier . doi: 10.1016/j.toxicon.2019.12.059

Convergent evolution of defensive venom components in spitting cobras

2020

Conference Publication

Discovery and characterisation of novel peptides from Amazonian stinging ant venoms with antiparasitic activity

Nixon, Samantha, Agwa, Akello, Robinson, Sam, Walker, Andrew, Touchard, Axel, Schroeder, Christina, Vetter, Irina, Kotze, Andrew C., Herzig, Volker and King, Glenn F. (2020). Discovery and characterisation of novel peptides from Amazonian stinging ant venoms with antiparasitic activity. 20th World Congress of the International-Society-on-Toxinology, Buenos Aires, Argentina, 8-13 September 2019. Oxford, United Kingdom: Elsevier.

Discovery and characterisation of novel peptides from Amazonian stinging ant venoms with antiparasitic activity

2019

Conference Publication

Efficacy Of Voltage-Gated Sodium Channel Subtype Selective Compounds In A Novel Zebrafish Model For Dravet Syndrome

Weuring, W. J., Singh, S., Volkers, L., Rook, M., van't Slot, R. H., Inserra, M., Vetter, I., Verhoeven-Duif, N. M., Braun, K. P. J., Rivara, M. and Koeleman, B. P. C. (2019). Efficacy Of Voltage-Gated Sodium Channel Subtype Selective Compounds In A Novel Zebrafish Model For Dravet Syndrome. 33rd International Epilepsy Congress, Bangkok Thailand, Jun 22-26, 2019. HOBOKEN: WILEY.

Efficacy Of Voltage-Gated Sodium Channel Subtype Selective Compounds In A Novel Zebrafish Model For Dravet Syndrome

2019

Conference Publication

New insights in ω-conotoxin analgesic efficacy in postsurgical pain and oxaliplatin/cisplatin induced peripheral neuropathy

Hasan, Mahadhi, Mueller, Alexander, Starobova, Hana, Vetter, Irina, Cardoso, Fernanda C. and Lewis, Richard J. (2019). New insights in ω-conotoxin analgesic efficacy in postsurgical pain and oxaliplatin/cisplatin induced peripheral neuropathy. Brisbane Pain Research Symposium: Multidisciplinary Perspectives & Therapeutics 2019, Brisbane, QLD Australia, 29 November 2019.

New insights in ω-conotoxin analgesic efficacy in postsurgical pain and oxaliplatin/cisplatin induced peripheral neuropathy

2018

Conference Publication

Role of voltage-gated sodium channel isoforms in colon-innervating neurons in mice

Erickson, A., Garcia-Caraballo, S., Castro, J., Grundy, L., Rychkov, G., Vetter, I., Lewis, R., King, G. and Brierley, S. (2018). Role of voltage-gated sodium channel isoforms in colon-innervating neurons in mice. HOBOKEN: WILEY.

Role of voltage-gated sodium channel isoforms in colon-innervating neurons in mice

2018

Conference Publication

Jararhagin, a metalloproteinase from Bothrops jararaca venom, induces mechanical and thermal hyperalgesia through TRPV1 channel activation

Ferraz, C. R., Cardos, F. C., Clissa, P. B., Vetter, I., Verri Jr, W. A. and Lewis, R. J. (2018). Jararhagin, a metalloproteinase from Bothrops jararaca venom, induces mechanical and thermal hyperalgesia through TRPV1 channel activation. Brisbane Pain Research: Multidisciplinary Perspectives & Therapeutics 2018, Brisbane, QLD, Australia, 7 December 2018.

Jararhagin, a metalloproteinase from Bothrops jararaca venom, induces mechanical and thermal hyperalgesia through TRPV1 channel activation

2018

Conference Publication

The use of peptide-membrane interactions in the design of selective and potent sodium channel inhibitors

Schroeder, Christina, Agwa, Akello, Mueller, Alexander, Chow, Chun Yuen, Peigneur, Steve, Lawrence, Nicole, Deplazes, Evelyne, Mark, Alan, Craik, David, Tytgat, Jan, King, Glenn, Vetter, Irina and Henriques, Sonia Troeira (2018). The use of peptide-membrane interactions in the design of selective and potent sodium channel inhibitors. 35th European Peptide Symposium, Dublin City University, Ireland, 26-31 August 2018. Oxford, United Kingdom: John Wiley & Sons.

The use of peptide-membrane interactions in the design of selective and potent sodium channel inhibitors

2016

Conference Publication

Rational design and synthesis of a novel membrane binding NaV1.8 selective inhibitor with in vivo activity in pain models

Schroeder, Christina I., Deuis, Jennifer, Henriques, Sonia Troeria, Dekan, Zoltan, Inserra, Marco, Mobli, Mehdi and Vetter, Irina (2016). Rational design and synthesis of a novel membrane binding NaV1.8 selective inhibitor with in vivo activity in pain models. 60th Annual Meeting of the Biophysical Society, Los Angeles, CA, United States, 27 Feb - 2 Mar 2016. CAMBRIDGE: CELL PRESS. doi: 10.1016/j.bpj.2015.11.247

Rational design and synthesis of a novel membrane binding NaV1.8 selective inhibitor with in vivo activity in pain models

2016

Conference Publication

Miklos Bodanszky Award Lecture Probing the Functional Complexity of Ancient Oxytocin in Health and Disease

Muttenthaler, Markus, Andersson, Asa, Ragnarsson, Lotten, Vetter, Irina, Busnelli, Marta, Chini, Bice, Arrowsmith, Sarah, Wray, Susan, de Araujo, Aline Dantas, Dutertre, Sebastien, Mobli, Mehdi, Lewis, Richard J., Gruber, Christian W. and Alewood, Paul F. (2016). Miklos Bodanszky Award Lecture Probing the Functional Complexity of Ancient Oxytocin in Health and Disease. 34th European Peptide Symposium, Leipzig, Germany, 4‐9 September 2016. Hoboken, NJ United States: Wiley.

Miklos Bodanszky Award Lecture Probing the Functional Complexity of Ancient Oxytocin in Health and Disease

2016

Conference Publication

Study of the involvement of itch mediators in the neuropeptide release induced by Pacific-Ciguatoxin-2 in a co-culture model of sensory neurons and keratinocytes

L'herondelle, K., Philippe, R., Mignen, O., Vetter, I., Lewis, R. J., Misery, L. and Le Garrec, R. (2016). Study of the involvement of itch mediators in the neuropeptide release induced by Pacific-Ciguatoxin-2 in a co-culture model of sensory neurons and keratinocytes. 22nd Meeting of the French-Society-of-Toxinology (SFET), Paris, France, 10-11 December 2014. Kidlington, Oxford, United Kingdom: Pergamon Press. doi: 10.1016/j.toxicon.2016.01.007

Study of the involvement of itch mediators in the neuropeptide release induced by Pacific-Ciguatoxin-2 in a co-culture model of sensory neurons and keratinocytes

2015

Conference Publication

Rational development of novel analgesics for the treatment of chronic pain: Structure-Function studies of an engineered Nav1.7 blocker

Rahnama, S., Lachlan, R., Cardoso, F. C., Smith, J., Deuis, J., Vetter, I., King, G. F. and Mobli, M. (2015). Rational development of novel analgesics for the treatment of chronic pain: Structure-Function studies of an engineered Nav1.7 blocker. The 40th Lorne Conference on Protein Structure and Function, Lorne VIC, Australia, 8-12 February 2015.

Rational development of novel analgesics for the treatment of chronic pain: Structure-Function studies of an engineered Nav1.7 blocker

2014

Conference Publication

AMTB, an inhibitor of calcium permeable ion channel TRPM8 and its effect on breast cancer cells

Yapa, K., Peters, A. A., Vetter, I., Roberts-Thomson, S. J. and Monteith, G. R. (2014). AMTB, an inhibitor of calcium permeable ion channel TRPM8 and its effect on breast cancer cells. FEBS EMBO 2014 Conference, Paris, France, 30 August - 4 September 2014 . Chichester, West Sussex United Kingdom: Wiley-Blackwell.

AMTB, an inhibitor of calcium permeable ion channel TRPM8 and its effect on breast cancer cells

2014

Conference Publication

Effets de la ciguatoxine P-CTX-2 sur la liberation induite de neuropeptides dans un modele de co-culture keratinocytes-neurones sensoriels

L'herondelle, K., Philippe, R., Mignen, O., Vetter, I., Lewis, R. J., Misery, L. and Le Garrec, R. (2014). Effets de la ciguatoxine P-CTX-2 sur la liberation induite de neuropeptides dans un modele de co-culture keratinocytes-neurones sensoriels. 32e Congrès Annuel de Recherche Dermatologique (CARD), Océanopolis, Brest, France, 25-27 June, 2014. Issy les Moulineaux, France: Elsevier Masson. doi: 10.1016/j.annder.2014.04.154

Effets de la ciguatoxine P-CTX-2 sur la liberation induite de neuropeptides dans un modele de co-culture keratinocytes-neurones sensoriels

2014

Conference Publication

AMTB, a TRPM8 channel blocker also inhibits voltage gated sodium channels (Nav) in breast cancer cells

Yapa, Kunsala T.D.S, Peters, Amelia A., Vetter, Irina and Roberts-Thomson, Sarah J. (2014). AMTB, a TRPM8 channel blocker also inhibits voltage gated sodium channels (Nav) in breast cancer cells. ASCEPT-MPGPCR Joint Scientific Meeting, Melbourne, VIC, Australia, 7-11 December 2014.

AMTB, a TRPM8 channel blocker also inhibits voltage gated sodium channels (Nav) in breast cancer cells

2014

Conference Publication

Discovery of voltage-gated sodium channel inhibitors from tarantula venoms

Cardoso, F. C., Dekan, Z., Anangi, R., Rosengren, K. J., Erickson, A., Vetter, I., Herzig, V., Alewood, P., King, G. F. and Lewis, R. J. (2014). Discovery of voltage-gated sodium channel inhibitors from tarantula venoms. Venom to Drugs Conference 2014, Kingscliffe, NSW, Australia, 19-23 October 2014.

Discovery of voltage-gated sodium channel inhibitors from tarantula venoms

2013

Conference Publication

Ciguatoxin-Induced Release of Neuropeptides in a Sensory Neuron-Keratinocyte Coculture Model

Le Garrec, Raphaele, Vetter, Irina, Lewis, Richard J. and Misery, Laurent (2013). Ciguatoxin-Induced Release of Neuropeptides in a Sensory Neuron-Keratinocyte Coculture Model. World Congress on Itch (WCI), Boston, MA United States, 21–23 September 2013. UPPSALA: ACTA DERMATO-VENEREOLOGICA. doi: 10.2340/00015555-1701

Ciguatoxin-Induced Release of Neuropeptides in a Sensory Neuron-Keratinocyte Coculture Model

2012

Conference Publication

Development of high throughput calcium channel assays to accelerate the discovery of novel toxins targeting human cav2.2 channels

Sousa, Silmara R., Ragnarsson, Lotten, Vetter, Irina, Herzig, Volker, King, Glenn F. and Lewis, Richard J. (2012). Development of high throughput calcium channel assays to accelerate the discovery of novel toxins targeting human cav2.2 channels. 7th World Congress of the International Society on Toxinology & Venom Week 2012, 4th International Scientific Symposium on All Things Venomous, Honolulu, Hawaii, 8 - 13 July 2012. Oxford, United Kingdom: Pergamon. doi: 10.1016/j.toxicon.2012.04.033

Development of high throughput calcium channel assays to accelerate the discovery of novel toxins targeting human cav2.2 channels