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2014

Journal Article

Vancomycin-associated nephrotoxicity in the critically ill: a retrospective multivariate regression analysis

Hanrahan, Timothy P., Harlow, Georgina, Hutchinson, James, Dulhunty, Joel M., Lipman, Jeffrey, Whitehouse, Tony and Roberts, Jason A. (2014). Vancomycin-associated nephrotoxicity in the critically ill: a retrospective multivariate regression analysis. Critical Care Medicine, 42 (12), 2527-2536. doi: 10.1097/CCM.0000000000000514

Vancomycin-associated nephrotoxicity in the critically ill: a retrospective multivariate regression analysis

2014

Journal Article

Extended versus bolus infusion of meropenem and piperacillin: a pharmacolcinetic analysis

De Waele, J., Carlier, M., Hoste, E., Depuydt, P., Decruyenaere, J., Wallis, S. C., Lipman, J. and Roberts, J. A. (2014). Extended versus bolus infusion of meropenem and piperacillin: a pharmacolcinetic analysis. Minerva Anestesiologica, 80 (12), 1302-1309.

Extended versus bolus infusion of meropenem and piperacillin: a pharmacolcinetic analysis

2014

Journal Article

Consensus guidelines for optimising antifungal drug delivery and monitoring to avoid toxicity and improve outcomes in patients with haematological malignancy, 2014

Chau, M. M., Kong, D. C. M., van Hal, S. J., Urbancic, K., Trubiano, J. A., Cassumbhoy, M., Wilkes, J., Cooper, C. M., Roberts, J. A., Marriott, D. J. E. and Worth, L. J. (2014). Consensus guidelines for optimising antifungal drug delivery and monitoring to avoid toxicity and improve outcomes in patients with haematological malignancy, 2014. Internal Medicine Journal, 44 (12), 1364-1388. doi: 10.1111/imj.12600

Consensus guidelines for optimising antifungal drug delivery and monitoring to avoid toxicity and improve outcomes in patients with haematological malignancy, 2014

2014

Journal Article

Therapeutic drug monitoring of antibiotics – author's reply

Roberts, Jason A. (2014). Therapeutic drug monitoring of antibiotics – author's reply. Lancet Infectious Diseases, 14 (12), 1181-1181. doi: 10.1016/S1473-3099(14)71007-2

Therapeutic drug monitoring of antibiotics – author's reply

2014

Journal Article

Determining the mechanisms underlying augmented renal drug clearance in the critically ill: use of exogenous marker compounds

Udy, Andrew A., Jarrett, Paul, Stuart, Janine, Lassig-Smith, Melissa, Starr, Therese, Dunlop, Rachel, Wallis, Steven C., Roberts, Jason A. and Lipman, Jeffrey (2014). Determining the mechanisms underlying augmented renal drug clearance in the critically ill: use of exogenous marker compounds. Critical Care, 18 (657) 657, 1-9. doi: 10.1186/s13054-014-0657-z

Determining the mechanisms underlying augmented renal drug clearance in the critically ill: use of exogenous marker compounds

2014

Journal Article

How do we use therapeutic drug monitoring to improve outcomes from severe infections in critically ill patients?

Wong, Gloria, Sime, Fekade Bruck, Lipman, Jeffrey and Roberts, Jason A. (2014). How do we use therapeutic drug monitoring to improve outcomes from severe infections in critically ill patients?. BMC Infectious Diseases, 14 (288) 288, 1-11. doi: 10.1186/1471-2334-14-288

How do we use therapeutic drug monitoring to improve outcomes from severe infections in critically ill patients?

2014

Journal Article

Vancomycin population pharmacokinetics during extracorporeal membrane oxygenation therapy: a matched cohort study

Donadello, Katia, Roberts, Jason A., Cristallini, Stefano, Beumier, Marjorie, Shekar, Kiran, Jacobs, Frederique, Belhaj, Asmae, Vincent, Jean-Louis, de Backer, Daniel and Taccone, Fabio Silvio (2014). Vancomycin population pharmacokinetics during extracorporeal membrane oxygenation therapy: a matched cohort study. Critical Care, 18 (632) 632, 1-10. doi: 10.1186/s13054-014-0632-8

Vancomycin population pharmacokinetics during extracorporeal membrane oxygenation therapy: a matched cohort study

2014

Journal Article

Interethnic differences in pharmacokinetics of antibacterials

Tsai, Danny, Jamal, Janattul-Ain, Davis, Joshua S., Lipman, Jeffrey and Roberts, Jason A. (2014). Interethnic differences in pharmacokinetics of antibacterials. Clinical Pharmacokinetics, 54 (3), 243-260. doi: 10.1007/s40262-014-0209-3

Interethnic differences in pharmacokinetics of antibacterials

2014

Journal Article

Select critically ill patients at risk of augmented renal clearance: experience in a Malaysian intensive care unit

Adnan, S., Ratnam, S., Kumar, S., Paterson, D., Lipman, J., Roberts, J. and Udy, A. A. (2014). Select critically ill patients at risk of augmented renal clearance: experience in a Malaysian intensive care unit. Anaesthesia And Intensive Care, 42 (6), 715-722. doi: 10.1177/0310057X1404200606

Select critically ill patients at risk of augmented renal clearance: experience in a Malaysian intensive care unit

2014

Journal Article

Meeting the challenges of advanced drug delivery in critical illness

Roberts, Jason A. and Fraser, John F. (2014). Meeting the challenges of advanced drug delivery in critical illness. Advanced Drug Delivery Reviews, 77, 1-2. doi: 10.1016/j.addr.2014.11.002

Meeting the challenges of advanced drug delivery in critical illness

2014

Journal Article

Population pharmacokinetics and dosing simulations of cefuroxime in critically ill patients: non-standard dosing approaches are required to achieve therapeutic exposures

Carlier, Mieke, Noe, Michael, Roberts, Jason A., Stove, Veronique, Verstraete, Alain G., Lipman, Jeffrey and De Waele, Jan J. (2014). Population pharmacokinetics and dosing simulations of cefuroxime in critically ill patients: non-standard dosing approaches are required to achieve therapeutic exposures. Journal of Antimicrobial Chemotherapy, 69 (10), 2797-2803. doi: 10.1093/jac/dku195

Population pharmacokinetics and dosing simulations of cefuroxime in critically ill patients: non-standard dosing approaches are required to achieve therapeutic exposures

2014

Journal Article

Low flucloxacillin concentrations in a patient with central nervous system infection: the need for plasma and cerebrospinal fluid drug monitoring in the ICU

Abdul-Aziz, Mohd H., McDonald, Craig, McWhinney, Brett, Ungerer, Jacobus P. J., Lipman, Jeffrey and Roberts, Jason A. (2014). Low flucloxacillin concentrations in a patient with central nervous system infection: the need for plasma and cerebrospinal fluid drug monitoring in the ICU. Annals of Pharmacotherapy, 48 (10), 1380-1384. doi: 10.1177/1060028014540610

Low flucloxacillin concentrations in a patient with central nervous system infection: the need for plasma and cerebrospinal fluid drug monitoring in the ICU

2014

Journal Article

Impact of loading doses on the time to adequate predicted beta-lactam concentrations in prolonged and continuous infusion dosing schemes: reply to Rhodes et al

Roberts, Jason A., Paul, Sanjoy K., Akova, Murat, Bassetti, Matteo, De Waele, Jan J., Dimopoulos, George, Kaukonen, Kirsi-Maija, Koulenti, Despoina, Martin, Claude, Montravers, Philippe, Rello, Jordi, Rhodes, Andrew, Starr, Therese, Wallis, Steven C. and Lipman, Jeffrey (2014). Impact of loading doses on the time to adequate predicted beta-lactam concentrations in prolonged and continuous infusion dosing schemes: reply to Rhodes et al. Clinical Infectious Diseases, 59 (6), 907-908. doi: 10.1093/cid/ciu403

Impact of loading doses on the time to adequate predicted beta-lactam concentrations in prolonged and continuous infusion dosing schemes: reply to Rhodes et al

2014

Journal Article

Plasma and cerebrospinal fluid concentrations of linezolid in neurosurgical critically ill patients with proven or suspected central nervous system infections

Luque, S., Grau, S., Alvarez-Lerma, F., Ferrandez, O., Campillo, N., Horcajada, J.P., Basas, M., Lipman, J. and Roberts, J.A. (2014). Plasma and cerebrospinal fluid concentrations of linezolid in neurosurgical critically ill patients with proven or suspected central nervous system infections. International Journal of Antimicrobial Agents, 44 (5), 409-415. doi: 10.1016/j.ijantimicag.2014.07.001

Plasma and cerebrospinal fluid concentrations of linezolid in neurosurgical critically ill patients with proven or suspected central nervous system infections

2014

Journal Article

How severe is antibiotic pharmacokinetic variability in critically ill patients and what can be done about it?

Felton, T. W., Hope, W. W. and Roberts, J. A. (2014). How severe is antibiotic pharmacokinetic variability in critically ill patients and what can be done about it?. Diagnostic Microbiology and Infectious Disease, 79 (4), 441-447. doi: 10.1016/j.diagmicrobio.2014.04.007

How severe is antibiotic pharmacokinetic variability in critically ill patients and what can be done about it?

2014

Journal Article

Amikacin dosing in the ICU: we now know more, but still not enough ...

De Rosa, Francesco G. and Roberts, Jason A. (2014). Amikacin dosing in the ICU: we now know more, but still not enough .... Intensive Care Medicine, 40 (7), 1033-1035. doi: 10.1007/s00134-014-3308-6

Amikacin dosing in the ICU: we now know more, but still not enough ...

2014

Journal Article

The impact of variation in renal replacement therapy settings on piperacillin, meropenem, and vancomycin drug clearance in the critically ill: an analysis of published literature and dosing regimens

Jamal, Janattul-Ain, Udy, Andrew A., Lipman, Jeffrey and Roberts, Jason A. (2014). The impact of variation in renal replacement therapy settings on piperacillin, meropenem, and vancomycin drug clearance in the critically ill: an analysis of published literature and dosing regimens. Critical Care Medicine, 42 (7), 1640-1650. doi: 10.1097/CCM.0000000000000317

The impact of variation in renal replacement therapy settings on piperacillin, meropenem, and vancomycin drug clearance in the critically ill: an analysis of published literature and dosing regimens

2014

Journal Article

Simultaneous determination of seven β-lactam antibiotics in human plasma for therapeutic drug monitoring and pharmacokinetic studies

Sime, Fekade Bruck, Roberts, Michael S., Roberts, Jason A. and Robertson, Thomas A. (2014). Simultaneous determination of seven β-lactam antibiotics in human plasma for therapeutic drug monitoring and pharmacokinetic studies. Journal of Chromatography B, 960, 134-144. doi: 10.1016/j.jchromb.2014.04.029

Simultaneous determination of seven β-lactam antibiotics in human plasma for therapeutic drug monitoring and pharmacokinetic studies

2014

Journal Article

Micafungin pharmacokinetic/pharmacodynamic adequacy for the treatment of invasive candidiasis in critically ill patients on continuous venovenous haemofiltration

Maseda, Emilio, Grau, Santiago, Villagran, Maria-Jose, Hernandez-Gancedo, Carmen, Lopez-Tofino, Araceli, Roberts, Jason A., Aguilar, Lorenzo, Luque, Sonia, Sevillano, David, Gimenez, Maria-Jose and Gilsanz, Fernando (2014). Micafungin pharmacokinetic/pharmacodynamic adequacy for the treatment of invasive candidiasis in critically ill patients on continuous venovenous haemofiltration. Journal of Antimicrobial Chemotherapy, 69 (6), 1624-1632. doi: 10.1093/jac/dku013

Micafungin pharmacokinetic/pharmacodynamic adequacy for the treatment of invasive candidiasis in critically ill patients on continuous venovenous haemofiltration

2014

Journal Article

Variable ganciclovir concentrations in a critically ill patient receiving continuous renal replacement therapy and plasma exchange?

Nunez-Nunez, Maria, Bellapart, Judith, O’Donoghue, Steven, McWhinney, Brett, Ungerer, Jacobus P. J., Lipman, Jeffrey and Roberts, Jason A. (2014). Variable ganciclovir concentrations in a critically ill patient receiving continuous renal replacement therapy and plasma exchange?. International journal of antimicrobial agents, 43 (6), 572-573. doi: 10.1016/j.ijantimicag.2014.03.001

Variable ganciclovir concentrations in a critically ill patient receiving continuous renal replacement therapy and plasma exchange?