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2025 Journal Article Population Pharmacokinetic Modelling of Remdesivir and Its Metabolite GS-441524 in Hospitalised Patients with COVID-19Roberts, Darren M., Liu, Xin, Parker, Suzanne L., Burke, Andrew, Peek, Jenny, Carland, Jane E., Murnion, Bridin, Seah, Vincent, Wallis, Steven C., Sumi, Chandra D., Pandey, Saurabh, Buscher, Hergen, Byrne, Anthony, Sandaradura, Indy, Bowen, David, Holz, Simon, Stewart, Adam G., Hajkowicz, Krispin M. and Roberts, Jason A. (2025). Population Pharmacokinetic Modelling of Remdesivir and Its Metabolite GS-441524 in Hospitalised Patients with COVID-19. Clinical Pharmacokinetics, 64 (5) e0022222, 1-14. doi: 10.1007/s40262-025-01496-2 |
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2025 Journal Article Correction of posaconazole concentrations for hypoalbuminemiaNix, David E., Sime, Fekade and Roberts, Jason A. (2025). Correction of posaconazole concentrations for hypoalbuminemia. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy. doi: 10.1002/phar.70021 |
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2025 Journal Article A Systematic Review of Pharmacokinetic Studies of Colistin and Polymyxin B in Adult PopulationsZamri, Puteri Juanita, Lim, Sazlyna Mohd Sazlly, Sime, Fekade Bruck, Roberts, Jason A. and Abdul-Aziz, Mohd Hafiz (2025). A Systematic Review of Pharmacokinetic Studies of Colistin and Polymyxin B in Adult Populations. Clinical Pharmacokinetics, 64 (5) n71, 1-35. doi: 10.1007/s40262-025-01488-2 |
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2025 Journal Article The FUSION Study: compatibility of antibiotics with commonly used medication infusions in a paediatric intensive care unitTu, Quyen, Won, Hayoung, Sime, Fekade Bruck, Raman, Sainath, Cotta, Menino Osbert, Wallis, Steven C., Marjanovic, Dusan, Stacey, Sonya, Schlapbach, Luregn and Roberts, Jason A. (2025). The FUSION Study: compatibility of antibiotics with commonly used medication infusions in a paediatric intensive care unit. European Journal of Hospital Pharmacy ejhpharm-2024-004450, ejhpharm-2024. doi: 10.1136/ejhpharm-2024-004450 |
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2025 Journal Article Optimising peri-operative intravenous lidocaine dosing regimensTognolini, Angela, Roberts, Jason A. and Eley, Victoria A. (2025). Optimising peri-operative intravenous lidocaine dosing regimens. Anaesthesia. doi: 10.1111/anae.16611 |
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2025 Journal Article Pharmacokinetics of Metronidazole During Prolonged Intermittent Kidney Replacement TherapyXu, Jessica H., Cheng, Vesa, Rawlins, Matthew, Morgan, David, Won, Hayoung, Wu, Xiaolin, Dyer, John and Roberts, Jason A. (2025). Pharmacokinetics of Metronidazole During Prolonged Intermittent Kidney Replacement Therapy. Hemodialysis International. doi: 10.1111/hdi.13242 |
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2025 Journal Article Quantifying cost savings from outpatient parenteral antimicrobial therapy programme: a systematic review and meta-analysisMohammed, Solomon Ahmed, Roberts, Jason A., Mirón-Rubio, Manuel, López Cortés, Luis Eduardo, Assefa, Getnet Mengistu, Pollard, James, McCarthy, Kate, Gilchrist, Mark, Cotta, Menino and Sime, Fekade B. (2025). Quantifying cost savings from outpatient parenteral antimicrobial therapy programme: a systematic review and meta-analysis. JAC-Antimicrobial Resistance, 7 (2) dlaf049, 1-11. doi: 10.1093/jacamr/dlaf049 |
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2025 Journal Article Optimizing ICU antifungal therapy: overcoming pharmacokinetic limitations with combination strategies—author's replyHernández-Mitre, María Patricia, Roberts, Jason A. and Roger, Claire (2025). Optimizing ICU antifungal therapy: overcoming pharmacokinetic limitations with combination strategies—author's reply. Intensive Care Medicine, 51 (4), 1-2. doi: 10.1007/s00134-025-07872-7 |
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2025 Journal Article Cefazolin versus placebo for surgical antibiotic prophylaxis in low-risk cesarean delivery: a feasibility blinded randomized controlled trialEley, Victoria A., Navarro, Severine, Martin, Elizabeth, Amoako, Akwasi, Hartel, Gunter, Woods, Christine, Lu, Yan, Lipman, Jeffrey, Roberts, Jason, Tang, Mimi and Callaway, Leonie (2025). Cefazolin versus placebo for surgical antibiotic prophylaxis in low-risk cesarean delivery: a feasibility blinded randomized controlled trial. BMC Pregnancy and Childbirth, 25 (1) 353. doi: 10.1186/s12884-025-07484-5 |
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2025 Journal Article In reply to the Letter to Editor regarding ‘Renal function and its impact on the concentration of ceftazidime-avibactam: A cross-sectional study’Angelini, Jacopo, Giuliano, Simone, Lanini, Simone, Ferin, Sara, Martini, Luca, Cossettini, Stella, Roberts, Jason, Baraldo, Massimo and Tascini, Carlo (2025). In reply to the Letter to Editor regarding ‘Renal function and its impact on the concentration of ceftazidime-avibactam: A cross-sectional study’. International Journal of Antimicrobial Agents, 65 (6) 107480, 107480. doi: 10.1016/j.ijantimicag.2025.107480 |
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2025 Journal Article Statistical documentation for multi-disease, multi-domain platform trials: our experience with the Staphylococcus aureus Network Adaptive Platform trialMahar, Robert K., McGlothlin, Anna, Dymock, Michael, Barina, Lauren, Bonten, Marc, Bowen, Asha, Cheng, Matthew P., Daneman, Nick, Goodman, Anna L., Lee, Todd C., Lewis, Roger J., Lumley, Thomas, McLean, Alistair R. D., McQuilten, Zoe, Mora, Jocelyn, Paterson, David L., Price, David J., Roberts, Jason, Snelling, Tom, Tverring, Jonas, Webb, Steve A., Yahav, Dafna, Davis, Joshua S., Tong, Steven Y. C., Marsh, Julie A., on behalf of the SNAP Global Trial Steering Committee, Boyles, Tom, Cosgrove, Catherine, Heriot, George ... Whiteway, Lynda (2025). Statistical documentation for multi-disease, multi-domain platform trials: our experience with the Staphylococcus aureus Network Adaptive Platform trial. Trials, 26 (1) 49, 1-7. doi: 10.1186/s13063-024-08684-8 |
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2025 Journal Article Are contemporary antifungal doses sufficient for critically ill patients? Outcomes from an international, multicenter pharmacokinetics study for Screening Antifungal Exposure in Intensive Care Units—the SAFE-ICU studyRoberts, Jason A., Sime, Fekade B., Lipman, Jeffrey, Hernández-Mitre, María Patricia, Baptista, João Pedro, Brüggemann, Roger J., Darvall, Jai, De Waele, Jan J., Dimopoulos, George, Lefrant, Jean-Yves, Mat Nor, Mohd Basri, Rello, Jordi, Seoane, Leonardo, Slavin, Monica A., Valkonen, Miia, Venditti, Mario, Ceccarelli, Giancarlo, Wong, Wai Tat, Zeitlinger, Markus and Roger, Claire (2025). Are contemporary antifungal doses sufficient for critically ill patients? Outcomes from an international, multicenter pharmacokinetics study for Screening Antifungal Exposure in Intensive Care Units—the SAFE-ICU study. Intensive Care Medicine, 51 (2), 1-16. doi: 10.1007/s00134-025-07793-5 |
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2025 Journal Article Is it a case of higher, the worse, or are beta-lactam antibiotics the innocent bystanders?Heffernan, Aaron J. and Roberts, Jason A. (2025). Is it a case of higher, the worse, or are beta-lactam antibiotics the innocent bystanders?. Journal of Critical Care, 85 154934, 154934. doi: 10.1016/j.jcrc.2024.154934 |
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2025 Journal Article Population pharmacokinetics of caspofungin in critically ill patients receiving extracorporeal membrane oxygenation—an ASAP ECMO studyAbdul-Aziz, Mohd H., Diehl, Arne, Liu, Xin, Cheng, Vesa, Corley, Amanda, Gilder, Eileen, Levkovich, Bianca, McGuinness, Shay, Ordonez, Jenny, Parke, Rachael, Pellegrino, Vincent, Wallis, Steven C., Fraser, John F., Shekar, Kiran and Roberts, Jason A. (2025). Population pharmacokinetics of caspofungin in critically ill patients receiving extracorporeal membrane oxygenation—an ASAP ECMO study. Antimicrobial Agents and Chemotherapy, 69 (2) e0143524, 1-15. doi: 10.1128/aac.01435-24 |
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2025 Journal Article Safety, tolerability and pharmacokinetics of subcutaneous cefazolin as an alternative to intravenous administrationMurray, Fionnuala, Yoo, Okhee, Brophy-Williams, Samuel, Rawlins, Matthew, Wallis, Steven C., Roberts, Jason A., Raby, Edward, Salman, Sam and Manning, Laurens (2025). Safety, tolerability and pharmacokinetics of subcutaneous cefazolin as an alternative to intravenous administration. Journal of Antimicrobial Chemotherapy, 80 (2), 347-353. doi: 10.1093/jac/dkae397 |
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2025 Journal Article Ceftriaxone population pharmacokinetics in plasma and cerebrospinal fluid of neurocritical care patientsKumta, Nilesh, Heffernan, Aaron J., Liu, Xin, Parker, Suzanne L., Cotta, Menino Osbert, Wallis, Steven C., Livermore, Amelia, Starr, Therese, Wai, Wong Tat, Joynt, Gavin M., Lipman, Jeffrey and Roberts, Jason A. (2025). Ceftriaxone population pharmacokinetics in plasma and cerebrospinal fluid of neurocritical care patients. International Journal of Antimicrobial Agents, 65 (5) 107461, 107461-5. doi: 10.1016/j.ijantimicag.2025.107461 |
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2025 Journal Article 211. Defining Optimal Sampling Times for Cefepime Therapeutic Drug Monitoring in Clinical PracticeRhodes, Nathaniel J, Smith, Brandon, Shields, Ryan K, Pan, Samantha, Weslander, Erin, Galvin, Shannon, Hughes, Jasmine, Hughes, Maria-Stephanie, Sime, Fekade B, Roberts, Jason A, Kiel, Patrick J, Neely, Michael N and Scheetz, Marc H (2025). 211. Defining Optimal Sampling Times for Cefepime Therapeutic Drug Monitoring in Clinical Practice. Open Forum Infectious Diseases, 12 (Supplement_1). doi: 10.1093/ofid/ofae631.069 |
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2025 Journal Article Evaluation of ampicillin plus ceftobiprole combination therapy in treating Enterococcus faecalis infective endocarditis and bloodstream infectionGiuliano, Simone, Angelini, Jacopo, Campanile, Floriana, Conti, Paola, Flammini, Sarah, Pagotto, Alberto, Sbrana, Francesco, Martini, Luca, D'Elia, Denise, Abdul-Aziz, Mohd H., Cotta, Menino O., Roberts, Jason A., Bonomo, Robert A. and Tascini, Carlo (2025). Evaluation of ampicillin plus ceftobiprole combination therapy in treating Enterococcus faecalis infective endocarditis and bloodstream infection. Scientific Reports, 15 (1) 3519, 1-16. doi: 10.1038/s41598-025-87512-8 |
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2025 Journal Article A pharmacokinetic/pharmacodynamic analysis of intravenous tranexamic acid in adult patients undergoing elective total hip arthroplasty (ORACLE)Gurunathan, Usha, Medcalf, Robert L., Chiang, Lily, Liu, Zikou, Liu, Xin, Keragala, Charithani B., Hernandez-Mitre, Maria Patricia, Brady, Paul, Wallis, Steven C., Roberts, Jason A., Mullany, Daniel, Nandurkar, Harshal, Eley, Victoria and Parker, Suzanne L. (2025). A pharmacokinetic/pharmacodynamic analysis of intravenous tranexamic acid in adult patients undergoing elective total hip arthroplasty (ORACLE). British Journal of Anaesthesia. doi: 10.1016/j.bja.2024.12.004 |
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2025 Journal Article Dosing optimisation of intravenous lidocaine in patients with class 1–3 obesity by population pharmacokinetic analysisTognolini, Angela R., Liu, Xin, Pandey, Saurabh, Roberts, Jason A., Wallis, Steven C., Jackson, Dwane and Eley, Victoria A. (2025). Dosing optimisation of intravenous lidocaine in patients with class 1–3 obesity by population pharmacokinetic analysis. Anaesthesia, 80 (5), 511-521. doi: 10.1111/anae.16531 |
