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2024

Journal Article

The impact of extracorporeal support on antimicrobial pharmacokinetics in critically ill neonatal and paediatric patients: a systematic review

Cree, Michele L., Abdul-Aziz, Mohd Hafiz, Schlapbach, Luregn J., Roberts, Jason A. and Parker, Suzanne (2024). The impact of extracorporeal support on antimicrobial pharmacokinetics in critically ill neonatal and paediatric patients: a systematic review. International Journal of Antimicrobial Agents, 64 (4) 107311, 1-16. doi: 10.1016/j.ijantimicag.2024.107311

The impact of extracorporeal support on antimicrobial pharmacokinetics in critically ill neonatal and paediatric patients: a systematic review

2024

Journal Article

Continuous infusion of beta-lactam antibiotics in critically ill patients with sepsis: implementation considerations

Barton, Greg, Rickard, Claire M. and Roberts, Jason A. (2024). Continuous infusion of beta-lactam antibiotics in critically ill patients with sepsis: implementation considerations. Intensive Care Medicine. doi: 10.1007/s00134-024-07650-x

Continuous infusion of beta-lactam antibiotics in critically ill patients with sepsis: implementation considerations

2024

Journal Article

Population pharmacokinetics of unbound cefazolin in infected hospitalized patients requiring intermittent high-flux haemodialysis: can a three-times-weekly post-dialysis dosing regimen provide optimal treatment?

Duke, Carleigh, Parker, Suzanne L, Zam, Betty B, Chiong, Fabian, Sajiv, Cherian, Pawar, Basant, Ashok, Aadith, Cooper, Brynley P, Tong, Steven Y C, Janson, Sonja, Wallis, Steven C, Roberts, Jason A and Tsai, Danny (2024). Population pharmacokinetics of unbound cefazolin in infected hospitalized patients requiring intermittent high-flux haemodialysis: can a three-times-weekly post-dialysis dosing regimen provide optimal treatment?. Journal of Antimicrobial Chemotherapy. doi: 10.1093/jac/dkae318

Population pharmacokinetics of unbound cefazolin in infected hospitalized patients requiring intermittent high-flux haemodialysis: can a three-times-weekly post-dialysis dosing regimen provide optimal treatment?

2024

Journal Article

Is there evidence on the optimal duration of aminoglycoside therapy in beta-lactam/aminoglycoside combination regimens used for the treatment of Gram-negative bacterial infections? -A Systematic Review

Wale, Yalew M., Roberts, Jason A., Wolie, Zenaw T. and Sime, Fekade B. (2024). Is there evidence on the optimal duration of aminoglycoside therapy in beta-lactam/aminoglycoside combination regimens used for the treatment of Gram-negative bacterial infections? -A Systematic Review. International Journal of Antimicrobial Agents, 64 (4) 107297, 107297. doi: 10.1016/j.ijantimicag.2024.107297

Is there evidence on the optimal duration of aminoglycoside therapy in beta-lactam/aminoglycoside combination regimens used for the treatment of Gram-negative bacterial infections? -A Systematic Review

2024

Journal Article

Unraveling the impact of therapeutic drug monitoring via machine learning for patients with sepsis

Ates, H. Ceren, Alshanawani, Abdallah, Hagel, Stefan, Cotta, Menino O., Roberts, Jason A., Dincer, Can and Ates, Cihan (2024). Unraveling the impact of therapeutic drug monitoring via machine learning for patients with sepsis. Cell Reports Medicine, 5 (8) 101681, 101681. doi: 10.1016/j.xcrm.2024.101681

Unraveling the impact of therapeutic drug monitoring via machine learning for patients with sepsis

2024

Journal Article

Can capillary microsampling facilitate a clinical pharmacokinetics study of cefazolin in critically ill children?

Dorofaeff, Tavey, Valero, Yarmarly Guerra, Coulthard, Mark G, Wallis, Steven C, Chatfield, Mark D, Lister, Paula, Lipman, Jeffrey, Roberts, Jason A and Parker, Suzanne L (2024). Can capillary microsampling facilitate a clinical pharmacokinetics study of cefazolin in critically ill children?. Bioanalysis, ahead-of-print (ahead-of-print), 1-9. doi: 10.1080/17576180.2024.2377912

Can capillary microsampling facilitate a clinical pharmacokinetics study of cefazolin in critically ill children?

2024

Journal Article

Propofol does not alter the protein binding and unbound concentration of lidocaine at clinically targeted plasma concentrations in vitro – A short communication

Tognolini, Angela R, Roberts, Jason A, Pandey, Saurabh, Wallis, Steven C and Eley, Victoria A (2024). Propofol does not alter the protein binding and unbound concentration of lidocaine at clinically targeted plasma concentrations in vitro – A short communication. Anaesthesia Critical Care & Pain Medicine, 43 (5) 101419, 101419. doi: 10.1016/j.accpm.2024.101419

Propofol does not alter the protein binding and unbound concentration of lidocaine at clinically targeted plasma concentrations in vitro – A short communication

2024

Journal Article

A systematic review of the pharmacokinetics and pharmacodynamics of novel beta-lactams and beta-lactam with beta-lactamase inhibitor combinations for the treatment of pneumonia caused by carbapenem-resistant Gram-negative bacteria

Rando, Emanuele, Novy, Emmanuel, Sangiorgi, Flavio, De Pascale, Gennaro, Fantoni, Massimo, Murri, Rita, Roberts, Jason A. and Cotta, Menino Osbert (2024). A systematic review of the pharmacokinetics and pharmacodynamics of novel beta-lactams and beta-lactam with beta-lactamase inhibitor combinations for the treatment of pneumonia caused by carbapenem-resistant Gram-negative bacteria. International Journal of Antimicrobial Agents, 64 (3) 107266, 107266. doi: 10.1016/j.ijantimicag.2024.107266

A systematic review of the pharmacokinetics and pharmacodynamics of novel beta-lactams and beta-lactam with beta-lactamase inhibitor combinations for the treatment of pneumonia caused by carbapenem-resistant Gram-negative bacteria

2024

Journal Article

Safety and efficacy of outpatient parenteral antimicrobial therapy: a systematic review and meta-analysis of randomized clinical trials

Mohammed, Solomon Ahmed, Roberts, Jason A, Cotta, Menino Osbert, Rogers, Benjamin, Pollard, James, Assefa, Getnet Mengistu, Erku, Daniel and Sime, Fekade B (2024). Safety and efficacy of outpatient parenteral antimicrobial therapy: a systematic review and meta-analysis of randomized clinical trials. International Journal of Antimicrobial Agents, 64 (2) 107263, 107263. doi: 10.1016/j.ijantimicag.2024.107263

Safety and efficacy of outpatient parenteral antimicrobial therapy: a systematic review and meta-analysis of randomized clinical trials

2024

Journal Article

Demographic, clinical and molecular epidemiology of extended-spectrum beta-lactamase-producing Escherichia coli bloodstream infections in Central Australia

Langham, Freya, Tsai, Danny, Forde, Brian M., Camilleri, Shayne, Harris, Patrick N.A., Roberts, Jason A. and Chiong, Fabian (2024). Demographic, clinical and molecular epidemiology of extended-spectrum beta-lactamase-producing Escherichia coli bloodstream infections in Central Australia. Pathology. doi: 10.1016/j.pathol.2024.04.013

Demographic, clinical and molecular epidemiology of extended-spectrum beta-lactamase-producing Escherichia coli bloodstream infections in Central Australia

2024

Journal Article

Continuous vs intermittent β-lactam antibiotic infusions in critically ill patients with sepsis : The BLING III Randomized Clinical Trial

Dulhunty, Joel M., Brett, Stephen J., De Waele, Jan J., Rajbhandari, Dorrilyn, Billot, Laurent, Cotta, Menino O., Davis, Joshua S., Finfer, Simon, Hammond, Naomi E., Knowles, Serena, Liu, Xiaoqiu, McGuinness, Shay, Mysore, Jayanthi, Paterson, David L., Peake, Sandra, Rhodes, Andrew, Roberts, Jason A., Roger, Claire, Shirwadkar, Charudatt, Starr, Therese, Taylor, Colman, Myburgh, John A., Lipman, Jeffrey, Bellomo, Rinaldo, Eastwood, Glenn, Peck, Leah, Young, Helen, Cheng, Andrew, Lau, Luke ... for the BLING III Study Investigators (2024). Continuous vs intermittent β-lactam antibiotic infusions in critically ill patients with sepsis : The BLING III Randomized Clinical Trial. JAMA, 332 (8), 629. doi: 10.1001/jama.2024.9779

Continuous vs intermittent β-lactam antibiotic infusions in critically ill patients with sepsis : The BLING III Randomized Clinical Trial

2024

Journal Article

Prolonged vs intermittent infusions of β-lactam antibiotics in adults with sepsis or septic shock: a systematic review and meta-analysis

Abdul-Aziz, Mohd H., Hammond, Naomi E., Brett, Stephen J., Cotta, Menino O., De Waele, Jan J., Devaux, Anthony, Di Tanna, Gian Luca, Dulhunty, Joel M., Elkady, Hatem, Eriksson, Lars, Hasan, M Shahnaz, Khan, Ayesha Bibi, Lipman, Jeffrey, Liu, Xiaoqiu, Monti, Giacomo, Myburgh, John, Novy, Emmanuel, Omar, Shahed, Rajbhandari, Dorrilyn, Roger, Claire, Sjövall, Fredrik, Zaghi, Irene, Zangrillo, Alberto, Delaney, Anthony and Roberts, Jason A. (2024). Prolonged vs intermittent infusions of β-lactam antibiotics in adults with sepsis or septic shock: a systematic review and meta-analysis. JAMA, 332 (8), 638. doi: 10.1001/jama.2024.9803

Prolonged vs intermittent infusions of β-lactam antibiotics in adults with sepsis or septic shock: a systematic review and meta-analysis

2024

Journal Article

Clinical guidance for unfractionated heparin dosing and monitoring in critically ill patients

Samimi, May N., Hale, Andrew, Schults, Jessica, Fischer, Andreas, Roberts, Jason A. and Dhanani, Jayesh (2024). Clinical guidance for unfractionated heparin dosing and monitoring in critically ill patients. Expert Opinion on Pharmacotherapy, ahead-of-print (ahead-of-print), 1-13. doi: 10.1080/14656566.2024.2364057

Clinical guidance for unfractionated heparin dosing and monitoring in critically ill patients

2024

Journal Article

Current practices and challenges of outpatient parenteral antimicrobial therapy: a narrative review

Wolie, Zenaw T., Roberts, Jason A., Gilchrist, Mark, McCarthy, Kate and Sime, Fekade B. (2024). Current practices and challenges of outpatient parenteral antimicrobial therapy: a narrative review. Journal of Antimicrobial Chemotherapy, 79 (9), 2083-2102. doi: 10.1093/jac/dkae177

Current practices and challenges of outpatient parenteral antimicrobial therapy: a narrative review

2024

Journal Article

Population pharmacokinetics of prophylactic cefoxitin in elective bariatric surgery patients: a prospective monocentric study

Novy, Emmanuel, Liu, Xin, Hernandez-Mitre, Maria Patricia, Belveyre, Thibaut, Scala-Bertola, Julien, Roberts, Jason A. and Parker, Suzanne L. (2024). Population pharmacokinetics of prophylactic cefoxitin in elective bariatric surgery patients: a prospective monocentric study. Anaesthesia Critical Care and Pain Medicine, 43 (3) 101376, 1-8. doi: 10.1016/j.accpm.2024.101376

Population pharmacokinetics of prophylactic cefoxitin in elective bariatric surgery patients: a prospective monocentric study

2024

Journal Article

COVID-19 Drug Treatments Are Prone to Sequestration in Extracorporeal Membrane Oxygenation Circuits: An Ex Vivo Extracorporeal Membrane Oxygenation Study

Dhanani, Jayesh A., Shekar, Kiran, Parmar, Dinesh, Lipman, Jeffrey, Bristow, Debra, Wallis, Steven C., Won, Hayoung, Sumi, Chandra D., Abdul-Aziz, Mohd H. and Roberts, Jason A. (2024). COVID-19 Drug Treatments Are Prone to Sequestration in Extracorporeal Membrane Oxygenation Circuits: An Ex Vivo Extracorporeal Membrane Oxygenation Study. ASAIO journal (American Society for Artificial Internal Organs : 1992), 70 (6), 546-552. doi: 10.1097/MAT.0000000000002120

COVID-19 Drug Treatments Are Prone to Sequestration in Extracorporeal Membrane Oxygenation Circuits: An Ex Vivo Extracorporeal Membrane Oxygenation Study

2024

Journal Article

TMPRSS2 inhibitors for the treatment of COVID-19 in adults: a systematic review and meta-analysis of randomized clinical trials of nafamostat and camostat mesylate

Hernández-Mitre, María Patricia, Morpeth, Susan C., Venkatesh, Balasubramanian, Hills, Thomas E., Davis, Joshua, Mahar, Robert K., McPhee, Grace, Jones, Mark, Totterdell, James, Tong, Steven Y. C. and Roberts, Jason A. (2024). TMPRSS2 inhibitors for the treatment of COVID-19 in adults: a systematic review and meta-analysis of randomized clinical trials of nafamostat and camostat mesylate. Clinical Microbiology and Infection, 30 (6), 743-754. doi: 10.1016/j.cmi.2024.01.029

TMPRSS2 inhibitors for the treatment of COVID-19 in adults: a systematic review and meta-analysis of randomized clinical trials of nafamostat and camostat mesylate

2024

Journal Article

Pooled Population Pharmacokinetic Analysis and Dose Recommendations for Ciprofloxacin in Intensive Care Unit Patients with Obesity

van Rhee, Koen P., Brüggemann, Roger J.M., Roberts, Jason A., Sjövall, Fredrik, van Hest, Reinier M., Elbers, Paul W.G., Abdulla, Alan, van der Linden, Paul D. and Knibbe, Catherijne A.J. (2024). Pooled Population Pharmacokinetic Analysis and Dose Recommendations for Ciprofloxacin in Intensive Care Unit Patients with Obesity. The Journal of Clinical Pharmacology, 64 (9), 1165-1172. doi: 10.1002/jcph.2450

Pooled Population Pharmacokinetic Analysis and Dose Recommendations for Ciprofloxacin in Intensive Care Unit Patients with Obesity

2024

Journal Article

Nimodipine prophylaxis in aneurysmal subarachnoid hemorrhage, a question of tradition or evidence: A scoping review

Bellapart, Judith, Laupland, Kevin B., Malacova, Eva, Roberts, Jason A. and Paratz, Jennifer (2024). Nimodipine prophylaxis in aneurysmal subarachnoid hemorrhage, a question of tradition or evidence: A scoping review. Journal of Clinical Neuroscience, 123, 91-99. doi: 10.1016/j.jocn.2024.03.016

Nimodipine prophylaxis in aneurysmal subarachnoid hemorrhage, a question of tradition or evidence: A scoping review

2024

Journal Article

Antimicrobial Therapeutic Drug Monitoring in critically ill adult patients -an international perspective on access, utilisation, and barriers

Williams, Paul, Cotta, Menino Osbert, Tabah, Alexis, Sandaradura, Indy, Kanji, Salmaan, Scheetz, Marc H., Imani, Sahand, Elhadi, Muhammed, Pardos, Sònia Luque, Schellack, Natalie, Sanches, Cristina, Timsit, Jean Francois, Xie, Jiao, Farkas, Andras, Wilks, Kathryn and Roberts, Jason A. (2024). Antimicrobial Therapeutic Drug Monitoring in critically ill adult patients -an international perspective on access, utilisation, and barriers. International Journal of Antimicrobial Agents, 64 (2) 107192, 107192. doi: 10.1016/j.ijantimicag.2024.107192

Antimicrobial Therapeutic Drug Monitoring in critically ill adult patients -an international perspective on access, utilisation, and barriers