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2026

Journal Article

Pharmacokinetics of intravenous ciprofloxacin for Legionella pneumonia during prolonged intermittent kidney replacement therapy: a case report and literature review

Scott, Donna, Salman, Sam, Ingram, Paul, McWhinney, Brett, Ungerer, Jacobus, Morgan, David, Roberts, Jason A. and Rawlins, Matthew (2026). Pharmacokinetics of intravenous ciprofloxacin for Legionella pneumonia during prolonged intermittent kidney replacement therapy: a case report and literature review. Renal Replacement Therapy, 12 (1) 39. doi: 10.1186/s41100-026-00738-8

Pharmacokinetics of intravenous ciprofloxacin for Legionella pneumonia during prolonged intermittent kidney replacement therapy: a case report and literature review

2026

Journal Article

Antimicrobial prophylaxis regimens in joint replacement surgery: susceptibility and PK/PD target attainment

Rivera, Alba, Luque, Sonia, Mur, Isabel, Puig-Verdié, Lluís, Gállego, Anna, Crusi, Xavier, Sorlí, Luisa, González, José Carlos, Horcajada, Juan Pablo, Navarro, Ferran, Roberts, Jason A. and Benito, Natividad (2026). Antimicrobial prophylaxis regimens in joint replacement surgery: susceptibility and PK/PD target attainment. International Journal of Antimicrobial Agents, 67 (11) 107947. doi: 10.1016/j.ijantimicag.2026.107947

Antimicrobial prophylaxis regimens in joint replacement surgery: susceptibility and PK/PD target attainment

2026

Journal Article

Population pharmacokinetics of piperacillin/tazobactam in critically ill pediatric patients

Dorofaeff, Tavey, Hernández-Mitre, María Patricia, Liu, Xin, Guerra Valero, Yarmarly C., Coulthard, Mark G., Lipman, Jeffrey, Wallis, Steven C., Maresco-Pennisi, Diane L., Parker, Suzane L. and Roberts, Jason A. (2026). Population pharmacokinetics of piperacillin/tazobactam in critically ill pediatric patients. Antimicrobial Agents and Chemotherapy e00272-26. doi: 10.1128/aac.00272-26

Population pharmacokinetics of piperacillin/tazobactam in critically ill pediatric patients

2026

Journal Article

Protein binding determination of cefepime, flucloxacillin, meropenem, piperacillin and tazobactam by ultrafiltration in critically ill patients: the choice of device matters

Gregoire, Matthieu, Wallis, Steven C., Williams, Paul G., Won, Hayoung, Hernández-Mitre, María Patricia, Abdul-Aziz, Mohd H. and Roberts, Jason A. (2026). Protein binding determination of cefepime, flucloxacillin, meropenem, piperacillin and tazobactam by ultrafiltration in critically ill patients: the choice of device matters. Clinical Pharmacokinetics, 1-12. doi: 10.1007/s40262-026-01659-9

Protein binding determination of cefepime, flucloxacillin, meropenem, piperacillin and tazobactam by ultrafiltration in critically ill patients: the choice of device matters

2026

Journal Article

The effects of continuous venovenous hemofiltration on immunosuppressive drug concentrations in an ex-vivo model of the critically Ill Adult: (CITRIC) study

Chumas, Lucy A., Wallis, Steven C., Sumi, Chandra, Abdul-Aziz, Mohd Hafiz, McWhinney, Brett C., Ungerer, Jacobus P. J., Coyer, Fiona, Ranganathan, Dwarakanathan, Roberts, Jason A. and Dhanani, Jayesh (2026). The effects of continuous venovenous hemofiltration on immunosuppressive drug concentrations in an ex-vivo model of the critically Ill Adult: (CITRIC) study. Artificial Organs aor.70211. doi: 10.1111/aor.70211

The effects of continuous venovenous hemofiltration on immunosuppressive drug concentrations in an ex-vivo model of the critically Ill Adult: (CITRIC) study

2026

Journal Article

Focused Update to International Consensus Recommendations for the Use of Prolonged‐Infusion Beta‐Lactam Antibiotics Among Severely Ill Adult Patients: Endorsed by the American College of Clinical Pharmacy, British Society for Antimicrobial Chemotherapy, Cystic Fibrosis Foundation, European Society of Clinical Microbiology and Infectious Diseases, Infectious Diseases Society of America, Society of Critical Care Medicine, and Society of Infectious Diseases Pharmacists

Hong, Lisa T., FakhriRavari, Alireza, Ulldemolins, Marta, Roberts, Jason A., Bonomo, Robert A., Scheetz, Marc H. and the Prolonged‐Infusion Beta‐Lactam Consensus Panel (2026). Focused Update to International Consensus Recommendations for the Use of Prolonged‐Infusion Beta‐Lactam Antibiotics Among Severely Ill Adult Patients: Endorsed by the American College of Clinical Pharmacy, British Society for Antimicrobial Chemotherapy, Cystic Fibrosis Foundation, European Society of Clinical Microbiology and Infectious Diseases, Infectious Diseases Society of America, Society of Critical Care Medicine, and Society of Infectious Diseases Pharmacists. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 46 (9) e70188, e70188-e70188. doi: 10.1002/phar.70188

Focused Update to International Consensus Recommendations for the Use of Prolonged‐Infusion Beta‐Lactam Antibiotics Among Severely Ill Adult Patients: Endorsed by the American College of Clinical Pharmacy, British Society for Antimicrobial Chemotherapy, Cystic Fibrosis Foundation, European Society of Clinical Microbiology and Infectious Diseases, Infectious Diseases Society of America, Society of Critical Care Medicine, and Society of Infectious Diseases Pharmacists

2026

Journal Article

Physiological determinants of piperacillin and cefazolin clearance in septic and trauma patients

Ulldemolins, Marta, Abdul-Aziz, Mohd Hafiz, Hernández-Mitre, María Patricia, Mohd Sazlly Lim, Sazlyna, Udy, Andrew A., Colmenero, Manuel, Kruger, Peter, Kirkpatrick, Carl M. J., Roberts, Michael S., Wallis, Steven C., Paterson, David L., Lipman, Jeffrey and Roberts, Jason A. (2026). Physiological determinants of piperacillin and cefazolin clearance in septic and trauma patients. Critical Care. doi: 10.1186/s13054-026-06239-8

Physiological determinants of piperacillin and cefazolin clearance in septic and trauma patients

2026

Journal Article

Determinants of levofloxacin prophylaxis failure in high-risk haematology patients: a prospective study integrating resistant colonization and pharmacokinetic/pharmacodynamic target attainment

Boşnak, Cemre, Metan, Gökhan, Zarakolu, Pınar, Karakulak, Elifcan Aladağ, Pınar, Aslı, Göker, Hakan, Roberts, Jason A, Hernandez-Mitre, Maria Patricia and Akova, Murat (2026). Determinants of levofloxacin prophylaxis failure in high-risk haematology patients: a prospective study integrating resistant colonization and pharmacokinetic/pharmacodynamic target attainment. Journal of Antimicrobial Chemotherapy, 81 (9) dkag284. doi: 10.1093/jac/dkag284

Determinants of levofloxacin prophylaxis failure in high-risk haematology patients: a prospective study integrating resistant colonization and pharmacokinetic/pharmacodynamic target attainment

2026

Journal Article

Vancomycin optimised dosing regimens for critically ill patients receiving renal replacement therapy

Ulldemolins, Marta, Lipman, Jeffrey, Liu, Xin, Abdul-Aziz, Mohd-Hafiz, Baptista, João P., Bilgrami, Irma, Bitker, Laurent, Boidin, Clement, Brinkmann, Alexander, Cheng, Vesa, Choi, Gordon, Cole, C. Louise, De Waele, Jan J., Deans, Renae, Eastwood, Glenn M., Escobar, Leslie, Frey, Otto R., Garreau, Romain, Goutelle, Sylvain, Gresham, Rebecca, Hernandez-Mitre, Maria Patricia, Jamal, Janattul Ain, Joynt, Gavin M., Kanji, Salmaan, Kielstein, Jan T., Kluge, Stefan, König, Christina, Koulouras, Vasilios P., Lassig-Smith, Melissa ... and the ESCMID PK/PD of Anti-Infectives Study Group (EPASG) (2026). Vancomycin optimised dosing regimens for critically ill patients receiving renal replacement therapy. Critical Care. doi: 10.1186/s13054-026-06226-z

Vancomycin optimised dosing regimens for critically ill patients receiving renal replacement therapy

2026

Journal Article

Pharmacokinetic and pharmacokinetic/pharmacodynamic (PK/PD) considerations of ceftaroline and ceftobiprole for the treatment of Staphylococcus aureus infections: a systematic review

Genovese, Camilla, Colaneri, Marta, Sguazzini, Enrico, Maddalena, Donatella, Abdul-Aziz, Mohd-Hafiz, Sime, Fekade B., Soriano, Alex, Gori, Andrea, Roberts, Jason A. and Ulldemolins, Marta (2026). Pharmacokinetic and pharmacokinetic/pharmacodynamic (PK/PD) considerations of ceftaroline and ceftobiprole for the treatment of Staphylococcus aureus infections: a systematic review. International Journal of Antimicrobial Agents 107959, 107959-107959. doi: 10.1016/j.ijantimicag.2026.107959

Pharmacokinetic and pharmacokinetic/pharmacodynamic (PK/PD) considerations of ceftaroline and ceftobiprole for the treatment of Staphylococcus aureus infections: a systematic review

2026

Journal Article

Population pharmacokinetics of total and free ceftriaxone in critically ill and non-critically ill hospitalised adult patients

Setiawan, Eko, Gonzalez, Alvaro, Wölky, Saskia A., Cotta, Menino Osbert, Liu, Xin, Sosilya, Hernycane, Maresco-Pennisi, Diane, Novy, Emmanuel, Ordonez, Jenny, Lukas, Dwi Lily, Wallis, Steven C., Xie, Jiao, Roberts, Jason A. and Abdul-Aziz, Mohd H. (2026). Population pharmacokinetics of total and free ceftriaxone in critically ill and non-critically ill hospitalised adult patients. International Journal of Antimicrobial Agents, 67 (8) 107817, 1-11. doi: 10.1016/j.ijantimicag.2026.107817

Population pharmacokinetics of total and free ceftriaxone in critically ill and non-critically ill hospitalised adult patients

2026

Journal Article

Consensus Guidance for Beta‐Lactam Antibiotic Dose Individualization in Acutely Ill Patients: Endorsed by the American College of Clinical Pharmacy, European Society of Clinical Microbiology and Infectious Diseases, European Society of Clinical Microbiology and Infectious Diseases PK/PD of Anti‐Infectives Study Group, Infectious Diseases Society of America, International Association of Therapeutic Drug Monitoring and Clinical Toxicology, Society of Critical Care Medicine, and the Society of Infectious Diseases Pharmacists

Barreto, Erin F., McCreary, Erin K., Pai Mangalore, Rekha, Tang Girdwood, Sonya, Arriola, Rebecca, Bens, Cynthia, Bonomo, Robert A., Edginton, Andrea N., Hong, Lisa T., Huttner, Angela, Koch, Birgit C. P., Maranchick, Nicole, Neely, Michael N., Peloquin, Charles R., Rao, Gauri G., Roberts, Jason A., Röhr, Anka C., Scheetz, Marc H., Schuetz, Audrey N., Yarnold, Paul R., Zuluaga, Andres and Rhodes, Nathaniel J. (2026). Consensus Guidance for Beta‐Lactam Antibiotic Dose Individualization in Acutely Ill Patients: Endorsed by the American College of Clinical Pharmacy, European Society of Clinical Microbiology and Infectious Diseases, European Society of Clinical Microbiology and Infectious Diseases PK/PD of Anti‐Infectives Study Group, Infectious Diseases Society of America, International Association of Therapeutic Drug Monitoring and Clinical Toxicology, Society of Critical Care Medicine, and the Society of Infectious Diseases Pharmacists. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 46 (8) e70181, e70181-e70181. doi: 10.1002/phar.70181

Consensus Guidance for Beta‐Lactam Antibiotic Dose Individualization in Acutely Ill Patients: Endorsed by the American College of Clinical Pharmacy, European Society of Clinical Microbiology and Infectious Diseases, European Society of Clinical Microbiology and Infectious Diseases PK/PD of Anti‐Infectives Study Group, Infectious Diseases Society of America, International Association of Therapeutic Drug Monitoring and Clinical Toxicology, Society of Critical Care Medicine, and the Society of Infectious Diseases Pharmacists

2026

Journal Article

Evaluation of short versus long course of tobramycin combined with piperacillin/tazobactam against antibiotic-resistant Pseudomonas aeruginosa in a hollow fibre infection model

Wale, Yalew M., Roberts, Jason A., Won, Hayoung, Reghu, Sheethal, Marjanovic, Dusan, Assefa, Getnet M., Permana, Budi, Ford, Brian and Sime, Fekade B. (2026). Evaluation of short versus long course of tobramycin combined with piperacillin/tazobactam against antibiotic-resistant Pseudomonas aeruginosa in a hollow fibre infection model. Antibiotics, 15 (7) 685. doi: 10.3390/antibiotics15070685

Evaluation of short versus long course of tobramycin combined with piperacillin/tazobactam against antibiotic-resistant Pseudomonas aeruginosa in a hollow fibre infection model

2026

Journal Article

Flucloxacillin plasma and urinary concentrations with and without probenecid and urinary biomarker profiles in healthy volunteers

Legg, Amy, Boast, Alison, Piera, Kim, Liu, Xin, Wallis, Steven C., McCarthy, James, Davis, Joshua S., Tong, Steven Y. C., Gwee, Amanda and Roberts, Jason A. (2026). Flucloxacillin plasma and urinary concentrations with and without probenecid and urinary biomarker profiles in healthy volunteers. British Journal of Clinical Pharmacology bcp.70663. doi: 10.1002/bcp.70663

Flucloxacillin plasma and urinary concentrations with and without probenecid and urinary biomarker profiles in healthy volunteers

2026

Journal Article

Predictive performance of an antibiotic precision dosing software program in critically ill adults with infection

Williams, Paul, Cotta, Menino Osbert, Wilks, Kathryn, Farkas, Andras, Spelman, Tim and Roberts, Jason A (2026). Predictive performance of an antibiotic precision dosing software program in critically ill adults with infection. Journal of Antimicrobial Chemotherapy, 81 (8) dkag234. doi: 10.1093/jac/dkag234

Predictive performance of an antibiotic precision dosing software program in critically ill adults with infection

2026

Journal Article

Optimizing intravenous amoxicillin for outpatient parenteral antimicrobial therapy

Wolie, Zenaw T, Roberts, Jason A, Wallis, Steven C, Assefa, Getnet M, Seaton, R Andrew, Gilchrist, Mark and Sime, Fekade B (2026). Optimizing intravenous amoxicillin for outpatient parenteral antimicrobial therapy. JAC-Antimicrobial Resistance, 8 (4) dlag165. doi: 10.1093/jacamr/dlag165

Optimizing intravenous amoxicillin for outpatient parenteral antimicrobial therapy

2026

Journal Article

External validation of a model informed precision dosing software for cefotaxime for treating critical ill infants and children

Tu, Quyen, Raman, Sainath, Cotta, Menino Osbert, Schlapbach, Luregn, Dorofaeff, Tavey, Farkas, Andras and Roberts, Jason A (2026). External validation of a model informed precision dosing software for cefotaxime for treating critical ill infants and children. Journal of Antimicrobial Chemotherapy, 81 (8) dkag235. doi: 10.1093/jac/dkag235

External validation of a model informed precision dosing software for cefotaxime for treating critical ill infants and children

2026

Journal Article

The impact of an ex vivo paediatric renal replacement therapy circuit on antimicrobial concentrations

Cree, Michele L., Abdul-Aziz, Mohd Hafiz, Wallis, Steven C., Won, Hayoung, Sumi, Chandra D., Marjanovic, Dusan, Ordonez, Jenny L., Schlapbach, Luregn J. and Roberts, Jason A. (2026). The impact of an ex vivo paediatric renal replacement therapy circuit on antimicrobial concentrations. Journal of Antimicrobial Chemotherapy, 81 (7) dkag189, 1-11. doi: 10.1093/jac/dkag189

The impact of an ex vivo paediatric renal replacement therapy circuit on antimicrobial concentrations

2026

Journal Article

Population pharmacokinetics of polymyxin B in critically ill patients with multidrug-resistant (MDR) Acinetobacter baumannii and Pseudomonas aeruginosa infections

Zamri, Puteri Juanita, Wölky, Saskia A., Hernandez-Mitre, Maria P., Liu, Xin, Hasan, M. Shahnaz, Shariff, Izyani Md, Sulaiman, Helmi, Wallis, Steven C., Sumi, Chandra Datta, Parker, Suzanne L., Sime, Fekade Bruck, Roberts, Jason A. and Abdul-Aziz, Mohd Hafiz (2026). Population pharmacokinetics of polymyxin B in critically ill patients with multidrug-resistant (MDR) Acinetobacter baumannii and Pseudomonas aeruginosa infections. International Journal of Antimicrobial Agents, 67 (7) 107816, 1-11. doi: 10.1016/j.ijantimicag.2026.107816

Population pharmacokinetics of polymyxin B in critically ill patients with multidrug-resistant (MDR) Acinetobacter baumannii and Pseudomonas aeruginosa infections

2026

Journal Article

A multicentre evaluation of pharmacokinetic/pharmacodynamic target attainment of piperacillin and tazobactam and the association with clinical outcomes in critically ill patients with sepsis and septic shock

Sulaiman, Helmi, Wölky, Saskia A., Rozali, Muhammad Azrai, Adiraju, Santosh K. S., Hasan, M. Shahnaz, Hernandez-Mitre, Maria Patricia, Liu, Xin, Mat-Nor, Mohd-Basri, Mazlan, Mohd Zulfakar, Salmuna, Zeti Norfidiyati, Wallis, Steven C., Xie, Jiao, Roberts, Jason A. and Abdul-Aziz, Mohd H. (2026). A multicentre evaluation of pharmacokinetic/pharmacodynamic target attainment of piperacillin and tazobactam and the association with clinical outcomes in critically ill patients with sepsis and septic shock. The Journal of Antimicrobial Chemotherapy, 81 (7) dkag199. doi: 10.1093/jac/dkag199

A multicentre evaluation of pharmacokinetic/pharmacodynamic target attainment of piperacillin and tazobactam and the association with clinical outcomes in critically ill patients with sepsis and septic shock