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2026

Journal Article

External validation of a model informed precision dosing software for cefotaxime for treating critical ill infants and children

Tu, Quyen, Raman, Sainath, Cotta, Menino Osbert, Schlapbach, Luregn, Dorofaeff, Tavey, Farkas, Andras and Roberts, Jason A (2026). External validation of a model informed precision dosing software for cefotaxime for treating critical ill infants and children. Journal of Antimicrobial Chemotherapy, 81 (8) dkag235. doi: 10.1093/jac/dkag235

External validation of a model informed precision dosing software for cefotaxime for treating critical ill infants and children

2026

Journal Article

Consensus Guidance for Beta‐Lactam Antibiotic Dose Individualization in Acutely Ill Patients: Endorsed by the American College of Clinical Pharmacy, European Society of Clinical Microbiology and Infectious Diseases, European Society of Clinical Microbiology and Infectious Diseases PK/PD of Anti‐Infectives Study Group, Infectious Diseases Society of America, International Association of Therapeutic Drug Monitoring and Clinical Toxicology, Society of Critical Care Medicine, and the Society of Infectious Diseases Pharmacists

Barreto, Erin F., McCreary, Erin K., Pai Mangalore, Rekha, Tang Girdwood, Sonya, Arriola, Rebecca, Bens, Cynthia, Bonomo, Robert A., Edginton, Andrea N., Hong, Lisa T., Huttner, Angela, Koch, Birgit C. P., Maranchick, Nicole, Neely, Michael N., Peloquin, Charles R., Rao, Gauri G., Roberts, Jason A., Röhr, Anka C., Scheetz, Marc H., Schuetz, Audrey N., Yarnold, Paul R., Zuluaga, Andres and Rhodes, Nathaniel J. (2026). Consensus Guidance for Beta‐Lactam Antibiotic Dose Individualization in Acutely Ill Patients: Endorsed by the American College of Clinical Pharmacy, European Society of Clinical Microbiology and Infectious Diseases, European Society of Clinical Microbiology and Infectious Diseases PK/PD of Anti‐Infectives Study Group, Infectious Diseases Society of America, International Association of Therapeutic Drug Monitoring and Clinical Toxicology, Society of Critical Care Medicine, and the Society of Infectious Diseases Pharmacists. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 46 (8) e70181, e70181-e70181. doi: 10.1002/phar.70181

Consensus Guidance for Beta‐Lactam Antibiotic Dose Individualization in Acutely Ill Patients: Endorsed by the American College of Clinical Pharmacy, European Society of Clinical Microbiology and Infectious Diseases, European Society of Clinical Microbiology and Infectious Diseases PK/PD of Anti‐Infectives Study Group, Infectious Diseases Society of America, International Association of Therapeutic Drug Monitoring and Clinical Toxicology, Society of Critical Care Medicine, and the Society of Infectious Diseases Pharmacists

2026

Journal Article

Evaluation of short versus long course of tobramycin combined with piperacillin/tazobactam against antibiotic-resistant Pseudomonas aeruginosa in a hollow fibre infection model

Wale, Yalew M., Roberts, Jason A., Won, Hayoung, Reghu, Sheethal, Marjanovic, Dusan, Assefa, Getnet M., Permana, Budi, Ford, Brian and Sime, Fekade B. (2026). Evaluation of short versus long course of tobramycin combined with piperacillin/tazobactam against antibiotic-resistant Pseudomonas aeruginosa in a hollow fibre infection model. Antibiotics, 15 (7) 685. doi: 10.3390/antibiotics15070685

Evaluation of short versus long course of tobramycin combined with piperacillin/tazobactam against antibiotic-resistant Pseudomonas aeruginosa in a hollow fibre infection model

2026

Journal Article

Flucloxacillin plasma and urinary concentrations with and without probenecid and urinary biomarker profiles in healthy volunteers

Legg, Amy, Boast, Alison, Piera, Kim, Liu, Xin, Wallis, Steven C., McCarthy, James, Davis, Joshua S., Tong, Steven Y. C., Gwee, Amanda and Roberts, Jason A. (2026). Flucloxacillin plasma and urinary concentrations with and without probenecid and urinary biomarker profiles in healthy volunteers. British Journal of Clinical Pharmacology bcp.70663. doi: 10.1002/bcp.70663

Flucloxacillin plasma and urinary concentrations with and without probenecid and urinary biomarker profiles in healthy volunteers

2026

Journal Article

The impact of an ex vivo paediatric renal replacement therapy circuit on antimicrobial concentrations

Cree, Michele L., Abdul-Aziz, Mohd Hafiz, Wallis, Steven C., Won, Hayoung, Sumi, Chandra D., Marjanovic, Dusan, Ordonez, Jenny L., Schlapbach, Luregn J. and Roberts, Jason A. (2026). The impact of an ex vivo paediatric renal replacement therapy circuit on antimicrobial concentrations. Journal of Antimicrobial Chemotherapy, 81 (7) dkag189, 1-11. doi: 10.1093/jac/dkag189

The impact of an ex vivo paediatric renal replacement therapy circuit on antimicrobial concentrations

2026

Journal Article

Population pharmacokinetics of polymyxin B in critically ill patients with multidrug-resistant (MDR) Acinetobacter baumannii and Pseudomonas aeruginosa infections

Zamri, Puteri Juanita, Wölky, Saskia A., Hernandez-Mitre, Maria P., Liu, Xin, Hasan, M. Shahnaz, Shariff, Izyani Md, Sulaiman, Helmi, Wallis, Steven C., Sumi, Chandra Datta, Parker, Suzanne L., Sime, Fekade Bruck, Roberts, Jason A. and Abdul-Aziz, Mohd Hafiz (2026). Population pharmacokinetics of polymyxin B in critically ill patients with multidrug-resistant (MDR) Acinetobacter baumannii and Pseudomonas aeruginosa infections. International Journal of Antimicrobial Agents, 67 (7) 107816, 1-11. doi: 10.1016/j.ijantimicag.2026.107816

Population pharmacokinetics of polymyxin B in critically ill patients with multidrug-resistant (MDR) Acinetobacter baumannii and Pseudomonas aeruginosa infections

2026

Journal Article

A multicentre evaluation of pharmacokinetic/pharmacodynamic target attainment of piperacillin and tazobactam and the association with clinical outcomes in critically ill patients with sepsis and septic shock

Sulaiman, Helmi, Wölky, Saskia A., Rozali, Muhammad Azrai, Adiraju, Santosh K. S., Hasan, M. Shahnaz, Hernandez-Mitre, Maria Patricia, Liu, Xin, Mat-Nor, Mohd-Basri, Mazlan, Mohd Zulfakar, Salmuna, Zeti Norfidiyati, Wallis, Steven C., Xie, Jiao, Roberts, Jason A. and Abdul-Aziz, Mohd H. (2026). A multicentre evaluation of pharmacokinetic/pharmacodynamic target attainment of piperacillin and tazobactam and the association with clinical outcomes in critically ill patients with sepsis and septic shock. The Journal of Antimicrobial Chemotherapy, 81 (7) dkag199. doi: 10.1093/jac/dkag199

A multicentre evaluation of pharmacokinetic/pharmacodynamic target attainment of piperacillin and tazobactam and the association with clinical outcomes in critically ill patients with sepsis and septic shock

2026

Journal Article

Benzylpenicillin Concentrations in Intrapartum Group B Streptococcus Prevention Guidelines; A Systematic Review of the Evidence

Deegan, Brian, Gourlay, Ashley, Eriksson, Lars, Roberts, Jason, Amoako, Akwasi and Eley, Victoria (2026). Benzylpenicillin Concentrations in Intrapartum Group B Streptococcus Prevention Guidelines; A Systematic Review of the Evidence. Australian and New Zealand Journal of Obstetrics and Gynaecology, 66 (4) e70153, 1-8. doi: 10.1111/ajo.70153

Benzylpenicillin Concentrations in Intrapartum Group B Streptococcus Prevention Guidelines; A Systematic Review of the Evidence

2026

Journal Article

Optimising therapeutic target attainment in vancomycin therapy for patients requiring intermittent haemodialysis

Tsai, Danny, Hernández-Mitre, María Patricia, Legg, Amy, Martin, Jacqueline, Sajiv, Cherian, Kodgire, Sachin, Naughton, William, Janson, Sonja, Hughes, Jaquelyne T., Liu, Xin and Roberts, Jason A. (2026). Optimising Therapeutic Target Attainment in Vancomycin Therapy for Patients Requiring Intermittent Haemodialysis. Nephrology, 31 (7) e70239, e70239-e70239. doi: 10.1111/nep.70239

Optimising therapeutic target attainment in vancomycin therapy for patients requiring intermittent haemodialysis

2026

Journal Article

Population pharmacokinetics of intravenous vitamin C in adults with sepsis: a sub-study of the LOVIT trial

Kanji, Salmaan, Hernandez-Mitre, Maria Patricia, Blain, Hugues, Adhikari, Neill K. J., Lamontagne, Francois, Battista, Marie-Claude, Menard, Julie, Sprague, Sheila, Masse, Marie-Helene, Roberts, Jason A. and LOVIT Investigators, (2026). Population Pharmacokinetics of Intravenous Vitamin C in Adults with Sepsis: A Sub-study of the LOVIT Trial. Clinical Pharmacokinetics, 65 (8), 1-12. doi: 10.1007/s40262-026-01648-y

Population pharmacokinetics of intravenous vitamin C in adults with sepsis: a sub-study of the LOVIT trial

2026

Journal Article

Cefazolin for Methicillin-Susceptible <i>Staphylococcus aureus</i> Bacteremia

Lee, Todd C., Barina, Lauren A., Walls, Genevieve, Goodman, Anna L., Yahav, Dafna, Cheng, Matthew P., Bonten, Marc, Bowen, Asha C., Boyles, Tom, Daneman, Nick, Ekkelenkamp, Miquel B., Ghanem-Zoubi, Nesrin, Hensgens, Marjolein P. M., Jager, Nynke G. L., Kaasch, Achim J., Kouijzer, Ilse J. E., Lewis, Roger J., Lumley, Thomas, Lye, David C., McDonald, Emily G., Mckew, Genevieve, McLean, Alistair R. D., McMullan, Brendan J., McQuilten, Zoe K., Morpeth, Susan C., Paterson, David L., Roberts, Jason A., Robinson, J. Owen, Saito, Hiroki ... Tong, Steven Y. C. (2026). Cefazolin for Methicillin-Susceptible Staphylococcus aureus Bacteremia. New England Journal of Medicine, 394 (23), 2329-2339. doi: 10.1056/nejmoa2506905

Cefazolin for Methicillin-Susceptible <i>Staphylococcus aureus</i> Bacteremia

2026

Journal Article

Direct oral challenge for penicillin allergy: a hospital implementation evaluation via the International Network of Antibiotic Allergy Nations (iNAAN) Study

Mitri, Elise A., Vogrin, Sara, Paynter, Camille, Fletcher, Luke R., Peter, Jonny, Powell, Neil, Barnes, Sara, Li, Philip H., Copaescu, Ana Maria, Turner, Nicholas A., James, Fiona, Sullivan, Richard, Masoum, Maryam Sherkat, Rawlins, Matthew, Mackay, Geoff, Smith, Benjamin J., Kilfoyle, Patricia, Forster, Daniel, Rose, Morgan, Cowan, Raquel, Alcorn, Kylie, Brischetto, Anna, Mahony, Andrew, Redmond, Andrew, Chakravorty, Arindam, Meher-Homji, Zaal, Yuson, Chino, Crawford, Simeon, Weeks, Greg ... Abdelaziz, Wisam (2026). Direct oral challenge for penicillin allergy: a hospital implementation evaluation via the International Network of Antibiotic Allergy Nations (iNAAN) Study. Clinical Infectious Diseases, 82 (6) ciag083, e1163-e1170. doi: 10.1093/cid/ciag083

Direct oral challenge for penicillin allergy: a hospital implementation evaluation via the International Network of Antibiotic Allergy Nations (iNAAN) Study

2026

Journal Article

Controversies on dosing of prophylactic nimodipine in subarachnoid haemorrhage, a narrative review

Bellapart, Judith, Hernández-Mitre, María Patricia, Yates, Charles, Paratz, Jennifer and Roberts, Jason A. (2026). Controversies on Dosing of Prophylactic Nimodipine in Subarachnoid Haemorrhage, a Narrative Review. Current Neuropharmacology, 24. doi: 10.2174/011570159x392453260415201526

Controversies on dosing of prophylactic nimodipine in subarachnoid haemorrhage, a narrative review

2026

Journal Article

Direct oral challenge for penicillin allergy: the International Network of Antibiotic Allergy Nations (iNAAN) Study

Mitri, Elise A., Fletcher, Luke R., Vogrin, Sara, Barnes, Sara, Powell, Neil, Peter, Jonny, Li, Philip H., Copaescu, Ana Maria, Turner, Nicholas A., James, Fiona, Paynter, Camille, Sullivan, Richard, Masoum, Maryam Sherkat, Rawlins, Matthew, Mackay, Geoff, Smith, Benjamin J., Kilfoyle, Patricia, Forster, Daniel, Rose, Morgan, Cowan, Raquel, Alcorn, Kylie, Brischetto, Anna, Mahony, Andrew, Redmond, Andrew, Chakravorty, Arindam, Meher-Homji, Zaal, Yuson, Chino, Crawford, Simeon, Weeks, Greg ... Abdelaziz, Wisam (2026). Direct oral challenge for penicillin allergy: the International Network of Antibiotic Allergy Nations (iNAAN) Study. Clinical Infectious Diseases, 82 (6) ciag082, e1148-e1162. doi: 10.1093/cid/ciag082

Direct oral challenge for penicillin allergy: the International Network of Antibiotic Allergy Nations (iNAAN) Study

2026

Journal Article

A novel meropenem dosing strategy for Outpatient Parenteral Antimicrobial Therapy (OPAT): a pilot pharmacokinetic/pharmacodynamic study in non-critically ill patients

Briquet, Caroline, Ngougni Pokem, Perrin, Liu, Xin, Wijnant, Gert-Jan, Cornu, Olivier, Yildiz, Halil, Verroken, Alexia, Roberts, Jason A., Yombi, Jean Cyr and Van Bambeke, Françoise (2026). A novel meropenem dosing strategy for Outpatient Parenteral Antimicrobial Therapy (OPAT): a pilot pharmacokinetic/pharmacodynamic study in non-critically ill patients. Antimicrobial Agents and Chemotherapy, 70 (7) e00372-26, 1-14. doi: 10.1128/aac.00372-26

A novel meropenem dosing strategy for Outpatient Parenteral Antimicrobial Therapy (OPAT): a pilot pharmacokinetic/pharmacodynamic study in non-critically ill patients

2026

Journal Article

Prospective evaluation of therapeutic target attainment with a beta-lactam dosing nomogram in critically ill adult patients

Williams, Paul, Cotta, Menino Osbert, Abdul-Aziz, Mohd H., Wilks, Kathryn, Murray, Lauren, Wallis, Steven C., Beall, Gareth and Roberts, Jason A. (2026). Prospective evaluation of therapeutic target attainment with a beta-lactam dosing nomogram in critically ill adult patients. International Journal of Antimicrobial Agents, 67 (9) 107883, 1-6. doi: 10.1016/j.ijantimicag.2026.107883

Prospective evaluation of therapeutic target attainment with a beta-lactam dosing nomogram in critically ill adult patients

2026

Journal Article

Defining optimal sampling strategies for cefepime model-informed precision dosing

Valadez, Adrian, Smith, Brandon J., Shields, Ryan K., Pan, Samantha, Weslander, Erin, Galvin, Shannon R., Hughes, Jasmine H., Hughes, Maria-Stephanie A., Sime, Fekade B., Roberts, Jason A., Kiel, Patrick J., Neely, Michael N., Scheetz, Marc H. and Rhodes, Nathaniel J. (2026). Defining Optimal Sampling Strategies for Cefepime Model-Informed Precision Dosing. Therapeutic Drug Monitoring. doi: 10.1097/ftd.0000000000001483

Defining optimal sampling strategies for cefepime model-informed precision dosing

2026

Journal Article

Evaluating the efficacy of ceftazidime/avibactam plus amikacin combination therapy as a carbapenem-sparing agent against ceftazidime/avibactam-resistant Escherichia coli using a hollow fiber infection model: a proof-of-concept study

Walker, Mikaela M., Roberts, Jason A., Li, Yixuan, Naicker, Saiyuri, Wallis, Steven C., Ordonez, Jenny L., Won, Hayoung, Forde, Brian M. and Sime, Fekade B. (2026). Evaluating the efficacy of ceftazidime/avibactam plus amikacin combination therapy as a carbapenem-sparing agent against ceftazidime/avibactam-resistant Escherichia coli using a hollow fiber infection model: a proof-of-concept study. Antimicrobial Agents and Chemotherapy, 70 (6) e01377-25, 1-12. doi: 10.1128/aac.01377-25

Evaluating the efficacy of ceftazidime/avibactam plus amikacin combination therapy as a carbapenem-sparing agent against ceftazidime/avibactam-resistant Escherichia coli using a hollow fiber infection model: a proof-of-concept study

2026

Journal Article

Impact of appropriate antimicrobial therapy on patient outcomes and antimicrobial use: a sub analysis of the DIANA Study Dataset

Cidade, José Pedro, Póvoa, Pedro, Depuydt, Pieter, Dhaese, Sofie, De Smet, Ken, Tabah, Alexis, Akova, Murat, Cotta, Menino Osbert, De Pascale, Gennaro, Dimopoulos, George, Fujitani, Shigeki, Garnacho-Montero, Jose, Leone, Marc, Lipman, Jeffrey, Ostermann, Marlies, Paiva, José-Artur, Schouten, Jeroen, Sjövall, Fredrik, Timsit, Jean-François, Roberts, Jason A., Zahar, Jean Ralph, Zand, Farid, Zirpe, Kapil, De Waele, Jan J., De Bus, Liesbet, Desai, Devashish, Laudanski, Krzysztof, Hatton, Kevin W., Hall, Anna ... Rios, Fernando (2026). Impact of appropriate antimicrobial therapy on patient outcomes and antimicrobial use: a sub analysis of the DIANA Study Dataset. Intensive Care Medicine, 52 (6), 1196-1209. doi: 10.1007/s00134-026-08448-9

Impact of appropriate antimicrobial therapy on patient outcomes and antimicrobial use: a sub analysis of the DIANA Study Dataset

2026

Journal Article

Early adequate linezolid concentrations and clinical outcomes in confirmed Gram-positive infections: the role of therapeutic drug monitoring

Fresán, Daniel, Sorlí, Luisa, Barceló-Vidal, Jaume, Rodrigo-Moreno, Ana, Muñoz, Rosana, Gracia, Maria Pilar, Subirana, Isaac, Ramos, Isabel, Cerro, Álvaro, Lucas, Álvaro, Roberts, Jason, Juanes, Ana Maria, Benítez-Cano, Adela and Luque, Sonia (2026). Early adequate linezolid concentrations and clinical outcomes in confirmed Gram-positive infections: the role of therapeutic drug monitoring. Journal of Antimicrobial Chemotherapy, 81 (6) dkag137. doi: 10.1093/jac/dkag137

Early adequate linezolid concentrations and clinical outcomes in confirmed Gram-positive infections: the role of therapeutic drug monitoring