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2025

Journal Article

Safety, tolerability and pharmacokinetics of subcutaneous cefazolin as an alternative to intravenous administration

Murray, Fionnuala, Yoo, Okhee, Brophy-Williams, Samuel, Rawlins, Matthew, Wallis, Steven C., Roberts, Jason A., Raby, Edward, Salman, Sam and Manning, Laurens (2025). Safety, tolerability and pharmacokinetics of subcutaneous cefazolin as an alternative to intravenous administration. Journal of Antimicrobial Chemotherapy, 80 (2), 347-353. doi: 10.1093/jac/dkae397

Safety, tolerability and pharmacokinetics of subcutaneous cefazolin as an alternative to intravenous administration

2025

Conference Publication

Defining Optimal Sampling Times for Cefepime Therapeutic Drug Monitoring in Clinical Practice

Rhodes, Nathaniel J., Smith, Brandon, Shields, Ryan K., Pan, Samantha, Weslander, Erin, Galvin, Shannon, Hughes, Jasmine, Hughes, Maria-Stephanie, Sime, Fekade B., Roberts, Jason A., Kiel, Patrick J., Neely, Michael N. and Scheetz, Marc H. (2025). Defining Optimal Sampling Times for Cefepime Therapeutic Drug Monitoring in Clinical Practice. IDWeek 2024, Los Angeles, CA United States, 16-19 October 2024. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/ofid/ofae631.069

Defining Optimal Sampling Times for Cefepime Therapeutic Drug Monitoring in Clinical Practice

2025

Journal Article

Evaluation of ampicillin plus ceftobiprole combination therapy in treating Enterococcus faecalis infective endocarditis and bloodstream infection

Giuliano, Simone, Angelini, Jacopo, Campanile, Floriana, Conti, Paola, Flammini, Sarah, Pagotto, Alberto, Sbrana, Francesco, Martini, Luca, D'Elia, Denise, Abdul-Aziz, Mohd H., Cotta, Menino O., Roberts, Jason A., Bonomo, Robert A. and Tascini, Carlo (2025). Evaluation of ampicillin plus ceftobiprole combination therapy in treating Enterococcus faecalis infective endocarditis and bloodstream infection. Scientific Reports, 15 (1) 3519, 1-16. doi: 10.1038/s41598-025-87512-8

Evaluation of ampicillin plus ceftobiprole combination therapy in treating Enterococcus faecalis infective endocarditis and bloodstream infection

2025

Journal Article

A pharmacokinetic/pharmacodynamic analysis of intravenous tranexamic acid in adult patients undergoing elective total hip arthroplasty (ORACLE)

Gurunathan, Usha, Medcalf, Robert L., Chiang, Lily, Liu, Zikou, Liu, Xin, Keragala, Charithani B., Hernandez-Mitre, Maria Patricia, Brady, Paul, Wallis, Steven C., Roberts, Jason A., Mullany, Daniel, Nandurkar, Harshal, Eley, Victoria and Parker, Suzanne L. (2025). A pharmacokinetic/pharmacodynamic analysis of intravenous tranexamic acid in adult patients undergoing elective total hip arthroplasty (ORACLE). British Journal of Anaesthesia. doi: 10.1016/j.bja.2024.12.004

A pharmacokinetic/pharmacodynamic analysis of intravenous tranexamic acid in adult patients undergoing elective total hip arthroplasty (ORACLE)

2025

Journal Article

Nebulized aminoglycosides for ventilator-associated pneumonia: methodological considerations and lessons from experimental studies

Rouby, Jean-Jacques, Xia, Jing, Dhanani, Jayesh, Bassi, Gianluigi Li, Monsel, Antoine, Torres, Antoni, Arvaniti, Kostoula, Assefi, Mona, Bassetti, Matteo, Blot, Stijn, Boisson, Matthieu, Bouglé, Adrien, Constantin, Jean-Michel, Dimopoulos, George, Dugernier, Jonathan, Dureau, Pauline, Ehrmann, Stephan, Felton, Timothy, Kollef, Marin, Koutsoukou, Antonia, Kyriakoudi, Anna, Laterre, Pierre-François, Leone, Marc, Lepère, Victoria, Liao, Xuelian, Mishra, Shakti Bedanta, Mimoz, Olivier, Nair, Girish B, Niederman, Michael ... Zhu, Ying-gang (2025). Nebulized aminoglycosides for ventilator-associated pneumonia: methodological considerations and lessons from experimental studies. Journal of Intensive Medicine, 5 (1), 12-22. doi: 10.1016/j.jointm.2024.07.006

Nebulized aminoglycosides for ventilator-associated pneumonia: methodological considerations and lessons from experimental studies

2025

Journal Article

Rezafungin acetate for the treatment of candidemia and invasive candidiasis: a pharmacokinetic evaluation

Bassetti, Matteo, Stewart, Adam, Bartalucci, Claudia, Vena, Antonio, Giacobbe, Daniele Roberto and Roberts, Jason (2025). Rezafungin acetate for the treatment of candidemia and invasive candidiasis: a pharmacokinetic evaluation. Expert Opinion On Drug Metabolism and Toxicology, 21 (2), 125-132. doi: 10.1080/17425255.2024.2424899

Rezafungin acetate for the treatment of candidemia and invasive candidiasis: a pharmacokinetic evaluation

2025

Journal Article

Evaluation of the stability of aciclovir in elastomeric infusion devices used for outpatient parenteral antimicrobial therapy

Sime, Fekade Bruck, Wallis, Steven, Jamieson, Conor, Hills, Tim, Gilchrist, Mark, Santillo, Mark, Seaton, R Andrew, Drummond, Felicity and Roberts, Jason (2025). Evaluation of the stability of aciclovir in elastomeric infusion devices used for outpatient parenteral antimicrobial therapy. European Journal of Hospital Pharmacy, 32 (3), 272-277. doi: 10.1136/ejhpharm-2023-003784

Evaluation of the stability of aciclovir in elastomeric infusion devices used for outpatient parenteral antimicrobial therapy

2025

Journal Article

Erratum to ‘TMPRSS2 inhibitors for the treatment of COVID-19 in adults: a systematic review and meta-analysis of randomized clinical trials of nafamostat and camostat mesylate’ [Clin Microbiol Infect (30) (2024) 743–754, (S1198743X24000557), (10.1016/j.cmi.2024.01.029)]

Hernández-Mitre, María Patricia, Morpeth, Susan C., Venkatesh, Balasubramanian, Hills, Thomas E., Davis, Joshua, Mahar, Robert K., McPhee, Grace, Jones, Mark, Totterdell, James, Tong, Steven Y.C. and Roberts, Jason A. (2025). Erratum to ‘TMPRSS2 inhibitors for the treatment of COVID-19 in adults: a systematic review and meta-analysis of randomized clinical trials of nafamostat and camostat mesylate’ [Clin Microbiol Infect (30) (2024) 743–754, (S1198743X24000557), (10.1016/j.cmi.2024.01.029)]. Clinical Microbiology and Infection, 31 (1) 141, 141-141. doi: 10.1016/j.cmi.2024.08.005

Erratum to ‘TMPRSS2 inhibitors for the treatment of COVID-19 in adults: a systematic review and meta-analysis of randomized clinical trials of nafamostat and camostat mesylate’ [Clin Microbiol Infect (30) (2024) 743–754, (S1198743X24000557), (10.1016/j.cmi.2024.01.029)]

2025

Journal Article

The pharmacokinetics of antibiotics in patients with obesity: a systematic review and consensus guidelines for dose adjustments

Märtson, Anne-Grete, Barber, Katie E, Crass, Ryan L, Hites, Maya, Kloft, Charlotte, Kuti, Joseph L, Nielsen, Elisabet I, Pai, Manjunath P, Zeitlinger, Markus, Roberts, Jason A and Tängdén, Thomas (2025). The pharmacokinetics of antibiotics in patients with obesity: a systematic review and consensus guidelines for dose adjustments. The Lancet Infectious Diseases, 25 (Pharmacology 31 1985), e504-e515. doi: 10.1016/S1473-3099(25)00155-0

The pharmacokinetics of antibiotics in patients with obesity: a systematic review and consensus guidelines for dose adjustments

2025

Journal Article

A fluconazole population pharmacokinetics study to improve target attainment in critically ill patients

Vuong, My-Luong, Elkayal, Omar, Van Daele, Ruth, Alffenaar, Jan-Willem C., Stocker, Sophie L., Roberts, Jason A., Debaveye, Yves, Wauters, Joost, Mertens, Beatrijs, Boonstra, Jasper M., Sandaradura, Indy, Marriott, Deborah J. E., Brüggemann, Roger J., Schouten, Jeroen A., Bergner, Raoul, Buijk, Steven, Spriet, Isabel and Dreesen, Erwin (2025). A fluconazole population pharmacokinetics study to improve target attainment in critically ill patients. Infection. doi: 10.1007/s15010-025-02663-0

A fluconazole population pharmacokinetics study to improve target attainment in critically ill patients

2025

Journal Article

Safety, tolerability and pharmacokinetics of subcutaneous meropenem as an alternative to intravenous administration

Murray, Fionnuala, Yoo, Okhee, Brophy-Williams, Samuel, Rawlins, Matthew, Wallis, Steven C., Roberts, Jason A., Raby, Edward, Salman, Sam and Manning, Laurens (2025). Safety, tolerability and pharmacokinetics of subcutaneous meropenem as an alternative to intravenous administration. Journal of Antimicrobial Chemotherapy, 80 (1), 209-215. doi: 10.1093/jac/dkae398

Safety, tolerability and pharmacokinetics of subcutaneous meropenem as an alternative to intravenous administration

2025

Journal Article

The changing epidemiology of Candida species in Asia Pacific and evidence for optimizing antifungal dosing in challenging clinical scenarios

Chen, Yee-Chun, Dhillon, Sohita, Adomakoh, Nicholas and Roberts, Jason A. (2025). The changing epidemiology of Candida species in Asia Pacific and evidence for optimizing antifungal dosing in challenging clinical scenarios. Expert Review of Anti-Infective Therapy, 1-15. doi: 10.1080/14787210.2025.2539427

The changing epidemiology of Candida species in Asia Pacific and evidence for optimizing antifungal dosing in challenging clinical scenarios

2024

Journal Article

Prolonged vs intermittent infusions of β-lactam antibiotics-reply

Roberts, Jason A., Devaux, Anthony and Abdul-Aziz, Mohd H. (2024). Prolonged vs intermittent infusions of β-lactam antibiotics-reply. JAMA-Journal of the American Medical Association, 333 (3), 259. doi: 10.1001/jama.2024.23728

Prolonged vs intermittent infusions of β-lactam antibiotics-reply

2024

Journal Article

A pooled pharmacokinetic analysis for piperacillin/tazobactam across different patient populations: From premature infants to the elderly

Kong, Daming, Roberts, Jason A., Lipman, Jeffrey, Taccone, Fabio Silvio, Cohen-Wolkowiez, Michael, Sime, Fekade B., Tsai, Danny, De Cock, Pieter A. J. G., Jaruratanasirikul, Sutep, Dhaese, Sofie A. M., Udy, Andrew A., Felton, Timothy W., Michelet, Robin, Thibault, Celine, Koomen, Jeroen V., Eleveld, Douglas J., Struys, Michel M. R. F., De Waele, Jan J., Colin, Pieter J., Damen, Caroline and PIP/TAZ Consortium (2024). A pooled pharmacokinetic analysis for piperacillin/tazobactam across different patient populations: From premature infants to the elderly. Clinical Pharmacokinetics, 64 (1) 769329, 107-126. doi: 10.1007/s40262-024-01460-6

A pooled pharmacokinetic analysis for piperacillin/tazobactam across different patient populations: From premature infants to the elderly

2024

Journal Article

Population pharmacokinetics of piperacillin-tazobactam in the plasma and cerebrospinal fluid of critically ill patients

Kumta, Nilesh, Heffernan, Aaron J., Cotta, Menino Osbert, Liu, Xin, Parker, Suzanne, Wallis, Steven, Livermore, Amelia, Starr, Therese, Wong, Wai Tat, Joynt, Gavin M., Lipman, Jeffrey and Roberts, Jason A. (2024). Population pharmacokinetics of piperacillin-tazobactam in the plasma and cerebrospinal fluid of critically ill patients. Antimicrobial Agents and Chemotherapy, 69 (2), e0060124. doi: 10.1128/aac.00601-24

Population pharmacokinetics of piperacillin-tazobactam in the plasma and cerebrospinal fluid of critically ill patients

2024

Journal Article

A systematic review and individual bacterial species level meta-analysis of in vitro studies on the efficacy of ceftazidime/avibactam combined with other antimicrobials against carbapenem-resistant Gram-negative bacteria

Assefa, Getnet M., Roberts, Jason A., Aslan, Abdullah T., Mohammed, Solomon A. and Sime, Fekade B. (2024). A systematic review and individual bacterial species level meta-analysis of in vitro studies on the efficacy of ceftazidime/avibactam combined with other antimicrobials against carbapenem-resistant Gram-negative bacteria. Journal of Antimicrobial Chemotherapy, 80 (2), 334-346. doi: 10.1093/jac/dkae451

A systematic review and individual bacterial species level meta-analysis of in vitro studies on the efficacy of ceftazidime/avibactam combined with other antimicrobials against carbapenem-resistant Gram-negative bacteria

2024

Journal Article

Continuous vs intermittent β-lactam antibiotic infusions for sepsis-Reply

Dulhunty, Joel M., Roberts, Jason A. and Lipman, Jeffrey (2024). Continuous vs intermittent β-lactam antibiotic infusions for sepsis-Reply. JAMA: The Journal of the American Medical Association, 333 (2), 174-175. doi: 10.1001/jama.2024.23275

Continuous vs intermittent β-lactam antibiotic infusions for sepsis-Reply

2024

Journal Article

Considerations for β-lactam antimicrobial continuous infusion. Authors’ reply to Massart et al. and Marzaroli et al

Barton, Greg, Rickard, Claire M. and Roberts, Jason A. (2024). Considerations for β-lactam antimicrobial continuous infusion. Authors’ reply to Massart et al. and Marzaroli et al. Intensive Care Medicine, 51 (1), 230-231. doi: 10.1007/s00134-024-07724-w

Considerations for β-lactam antimicrobial continuous infusion. Authors’ reply to Massart et al. and Marzaroli et al

2024

Journal Article

Dynamic in vitro PK/PD infection models for the development and optimisation of antimicrobial regimens: A narrative review

Wale, Yalew M., Roberts, Jason A. and Sime, Fekade B. (2024). Dynamic in vitro PK/PD infection models for the development and optimisation of antimicrobial regimens: A narrative review. Antibiotics, 13 (12) 1201, 1-23. doi: 10.3390/antibiotics13121201

Dynamic in vitro PK/PD infection models for the development and optimisation of antimicrobial regimens: A narrative review

2024

Journal Article

Demographic, clinical and molecular epidemiology of extended-spectrum beta-lactamase-producing Escherichia coli bloodstream infections in Central Australia

Langham, Freya, Tsai, Danny, Forde, Brian M., Camilleri, Shayne, Harris, Patrick N.A., Roberts, Jason A. and Chiong, Fabian (2024). Demographic, clinical and molecular epidemiology of extended-spectrum beta-lactamase-producing Escherichia coli bloodstream infections in Central Australia. Pathology, 56 (7), 1012-1020. doi: 10.1016/j.pathol.2024.04.013

Demographic, clinical and molecular epidemiology of extended-spectrum beta-lactamase-producing Escherichia coli bloodstream infections in Central Australia