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2025

Journal Article

The FUSION Study: compatibility of antibiotics with commonly used medication infusions in a paediatric intensive care unit

Tu, Quyen, Won, Hayoung, Sime, Fekade Bruck, Raman, Sainath, Cotta, Menino Osbert, Wallis, Steven C., Marjanovic, Dusan, Stacey, Sonya, Schlapbach, Luregn and Roberts, Jason A. (2025). The FUSION Study: compatibility of antibiotics with commonly used medication infusions in a paediatric intensive care unit. European Journal of Hospital Pharmacy ejhpharm-2024-004450. doi: 10.1136/ejhpharm-2024-004450

The FUSION Study: compatibility of antibiotics with commonly used medication infusions in a paediatric intensive care unit

2025

Journal Article

Optimising peri-operative intravenous lidocaine dosing regimens

Tognolini, Angela, Roberts, Jason A. and Eley, Victoria A. (2025). Optimising peri-operative intravenous lidocaine dosing regimens. Anaesthesia. doi: 10.1111/anae.16611

Optimising peri-operative intravenous lidocaine dosing regimens

2025

Journal Article

Pharmacokinetics of Metronidazole During Prolonged Intermittent Kidney Replacement Therapy

Xu, Jessica H., Cheng, Vesa, Rawlins, Matthew, Morgan, David, Won, Hayoung, Wu, Xiaolin, Dyer, John and Roberts, Jason A. (2025). Pharmacokinetics of Metronidazole During Prolonged Intermittent Kidney Replacement Therapy. Hemodialysis International. doi: 10.1111/hdi.13242

Pharmacokinetics of Metronidazole During Prolonged Intermittent Kidney Replacement Therapy

2025

Journal Article

Quantifying cost savings from outpatient parenteral antimicrobial therapy programme: a systematic review and meta-analysis

Mohammed, Solomon Ahmed, Roberts, Jason A., Mirón-Rubio, Manuel, López Cortés, Luis Eduardo, Assefa, Getnet Mengistu, Pollard, James, McCarthy, Kate, Gilchrist, Mark, Cotta, Menino and Sime, Fekade B. (2025). Quantifying cost savings from outpatient parenteral antimicrobial therapy programme: a systematic review and meta-analysis. JAC-Antimicrobial Resistance, 7 (2) dlaf049, 1-11. doi: 10.1093/jacamr/dlaf049

Quantifying cost savings from outpatient parenteral antimicrobial therapy programme: a systematic review and meta-analysis

2025

Journal Article

Optimizing ICU antifungal therapy: overcoming pharmacokinetic limitations with combination strategies—author's reply

Hernández-Mitre, María Patricia, Roberts, Jason A. and Roger, Claire (2025). Optimizing ICU antifungal therapy: overcoming pharmacokinetic limitations with combination strategies—author's reply. Intensive Care Medicine, 1-2. doi: 10.1007/s00134-025-07872-7

Optimizing ICU antifungal therapy: overcoming pharmacokinetic limitations with combination strategies—author's reply

2025

Journal Article

Cefazolin versus placebo for surgical antibiotic prophylaxis in low-risk cesarean delivery: a feasibility blinded randomized controlled trial

Eley, Victoria A., Navarro, Severine, Martin, Elizabeth, Amoako, Akwasi, Hartel, Gunter, Woods, Christine, Lu, Yan, Lipman, Jeffrey, Roberts, Jason, Tang, Mimi and Callaway, Leonie (2025). Cefazolin versus placebo for surgical antibiotic prophylaxis in low-risk cesarean delivery: a feasibility blinded randomized controlled trial. BMC Pregnancy and Childbirth, 25 (1) 353. doi: 10.1186/s12884-025-07484-5

Cefazolin versus placebo for surgical antibiotic prophylaxis in low-risk cesarean delivery: a feasibility blinded randomized controlled trial

2025

Journal Article

In reply to the Letter to Editor regarding ‘Renal function and its impact on the concentration of ceftazidime-avibactam: A cross-sectional study’

Angelini, Jacopo, Giuliano, Simone, Lanini, Simone, Ferin, Sara, Martini, Luca, Cossettini, Stella, Roberts, Jason, Baraldo, Massimo and Tascini, Carlo (2025). In reply to the Letter to Editor regarding ‘Renal function and its impact on the concentration of ceftazidime-avibactam: A cross-sectional study’. International Journal of Antimicrobial Agents, 65 (6) 107480, 107480. doi: 10.1016/j.ijantimicag.2025.107480

In reply to the Letter to Editor regarding ‘Renal function and its impact on the concentration of ceftazidime-avibactam: A cross-sectional study’

2025

Journal Article

Statistical documentation for multi-disease, multi-domain platform trials: our experience with the Staphylococcus aureus Network Adaptive Platform trial

Mahar, Robert K., McGlothlin, Anna, Dymock, Michael, Barina, Lauren, Bonten, Marc, Bowen, Asha, Cheng, Matthew P., Daneman, Nick, Goodman, Anna L., Lee, Todd C., Lewis, Roger J., Lumley, Thomas, McLean, Alistair R. D., McQuilten, Zoe, Mora, Jocelyn, Paterson, David L., Price, David J., Roberts, Jason, Snelling, Tom, Tverring, Jonas, Webb, Steve A., Yahav, Dafna, Davis, Joshua S., Tong, Steven Y. C., Marsh, Julie A., on behalf of the SNAP Global Trial Steering Committee, Boyles, Tom, Cosgrove, Catherine, Heriot, George ... Whiteway, Lynda (2025). Statistical documentation for multi-disease, multi-domain platform trials: our experience with the Staphylococcus aureus Network Adaptive Platform trial. Trials, 26 (1) 49, 1-7. doi: 10.1186/s13063-024-08684-8

Statistical documentation for multi-disease, multi-domain platform trials: our experience with the Staphylococcus aureus Network Adaptive Platform trial

2025

Journal Article

Are contemporary antifungal doses sufficient for critically ill patients? Outcomes from an international, multicenter pharmacokinetics study for Screening Antifungal Exposure in Intensive Care Units—the SAFE-ICU study

Roberts, Jason A., Sime, Fekade B., Lipman, Jeffrey, Hernández-Mitre, María Patricia, Baptista, João Pedro, Brüggemann, Roger J., Darvall, Jai, De Waele, Jan J., Dimopoulos, George, Lefrant, Jean-Yves, Mat Nor, Mohd Basri, Rello, Jordi, Seoane, Leonardo, Slavin, Monica A., Valkonen, Miia, Venditti, Mario, Ceccarelli, Giancarlo, Wong, Wai Tat, Zeitlinger, Markus and Roger, Claire (2025). Are contemporary antifungal doses sufficient for critically ill patients? Outcomes from an international, multicenter pharmacokinetics study for Screening Antifungal Exposure in Intensive Care Units—the SAFE-ICU study. Intensive Care Medicine, 51 (2), 1-16. doi: 10.1007/s00134-025-07793-5

Are contemporary antifungal doses sufficient for critically ill patients? Outcomes from an international, multicenter pharmacokinetics study for Screening Antifungal Exposure in Intensive Care Units—the SAFE-ICU study

2025

Journal Article

Population pharmacokinetics of caspofungin in critically ill patients receiving extracorporeal membrane oxygenation—an ASAP ECMO study

Abdul-Aziz, Mohd H., Diehl, Arne, Liu, Xin, Cheng, Vesa, Corley, Amanda, Gilder, Eileen, Levkovich, Bianca, McGuinness, Shay, Ordonez, Jenny, Parke, Rachael, Pellegrino, Vincent, Wallis, Steven C., Fraser, John F., Shekar, Kiran and Roberts, Jason A. (2025). Population pharmacokinetics of caspofungin in critically ill patients receiving extracorporeal membrane oxygenation—an ASAP ECMO study. Antimicrobial Agents and Chemotherapy, 69 (2) e0143524, 1-15. doi: 10.1128/aac.01435-24

Population pharmacokinetics of caspofungin in critically ill patients receiving extracorporeal membrane oxygenation—an ASAP ECMO study

2025

Journal Article

Ceftriaxone population pharmacokinetics in plasma and cerebrospinal fluid of neurocritical care patients

Kumta, Nilesh, Heffernan, Aaron J., Liu, Xin, Parker, Suzanne L., Cotta, Menino Osbert, Wallis, Steven C., Livermore, Amelia, Starr, Therese, Wai, Wong Tat, Joynt, Gavin M., Lipman, Jeffrey and Roberts, Jason A. (2025). Ceftriaxone population pharmacokinetics in plasma and cerebrospinal fluid of neurocritical care patients. International Journal of Antimicrobial Agents, 65 (5) 107461, 107461-5. doi: 10.1016/j.ijantimicag.2025.107461

Ceftriaxone population pharmacokinetics in plasma and cerebrospinal fluid of neurocritical care patients

2025

Journal Article

Safety, tolerability and pharmacokinetics of subcutaneous cefazolin as an alternative to intravenous administration

Murray, Fionnuala, Yoo, Okhee, Brophy-Williams, Samuel, Rawlins, Matthew, Wallis, Steven C., Roberts, Jason A., Raby, Edward, Salman, Sam and Manning, Laurens (2025). Safety, tolerability and pharmacokinetics of subcutaneous cefazolin as an alternative to intravenous administration. Journal of Antimicrobial Chemotherapy, 80 (2), 347-353. doi: 10.1093/jac/dkae397

Safety, tolerability and pharmacokinetics of subcutaneous cefazolin as an alternative to intravenous administration

2025

Journal Article

Is it a case of higher, the worse, or are beta-lactam antibiotics the innocent bystanders?

Heffernan, Aaron J. and Roberts, Jason A. (2025). Is it a case of higher, the worse, or are beta-lactam antibiotics the innocent bystanders?. Journal of Critical Care, 85 154934, 154934. doi: 10.1016/j.jcrc.2024.154934

Is it a case of higher, the worse, or are beta-lactam antibiotics the innocent bystanders?

2025

Journal Article

211. Defining Optimal Sampling Times for Cefepime Therapeutic Drug Monitoring in Clinical Practice

Rhodes, Nathaniel J, Smith, Brandon, Shields, Ryan K, Pan, Samantha, Weslander, Erin, Galvin, Shannon, Hughes, Jasmine, Hughes, Maria-Stephanie, Sime, Fekade B, Roberts, Jason A, Kiel, Patrick J, Neely, Michael N and Scheetz, Marc H (2025). 211. Defining Optimal Sampling Times for Cefepime Therapeutic Drug Monitoring in Clinical Practice. Open Forum Infectious Diseases, 12 (Supplement_1). doi: 10.1093/ofid/ofae631.069

211. Defining Optimal Sampling Times for Cefepime Therapeutic Drug Monitoring in Clinical Practice

2025

Journal Article

Evaluation of ampicillin plus ceftobiprole combination therapy in treating Enterococcus faecalis infective endocarditis and bloodstream infection

Giuliano, Simone, Angelini, Jacopo, Campanile, Floriana, Conti, Paola, Flammini, Sarah, Pagotto, Alberto, Sbrana, Francesco, Martini, Luca, D'Elia, Denise, Abdul-Aziz, Mohd H., Cotta, Menino O., Roberts, Jason A., Bonomo, Robert A. and Tascini, Carlo (2025). Evaluation of ampicillin plus ceftobiprole combination therapy in treating Enterococcus faecalis infective endocarditis and bloodstream infection. Scientific Reports, 15 (1) 3519, 1-16. doi: 10.1038/s41598-025-87512-8

Evaluation of ampicillin plus ceftobiprole combination therapy in treating Enterococcus faecalis infective endocarditis and bloodstream infection

2025

Journal Article

A pharmacokinetic/pharmacodynamic analysis of intravenous tranexamic acid in adult patients undergoing elective total hip arthroplasty (ORACLE)

Gurunathan, Usha, Medcalf, Robert L., Chiang, Lily, Liu, Zikou, Liu, Xin, Keragala, Charithani B., Hernandez-Mitre, Maria Patricia, Brady, Paul, Wallis, Steven C., Roberts, Jason A., Mullany, Daniel, Nandurkar, Harshal, Eley, Victoria and Parker, Suzanne L. (2025). A pharmacokinetic/pharmacodynamic analysis of intravenous tranexamic acid in adult patients undergoing elective total hip arthroplasty (ORACLE). British Journal of Anaesthesia. doi: 10.1016/j.bja.2024.12.004

A pharmacokinetic/pharmacodynamic analysis of intravenous tranexamic acid in adult patients undergoing elective total hip arthroplasty (ORACLE)

2025

Journal Article

Dosing optimisation of intravenous lidocaine in patients with class 1–3 obesity by population pharmacokinetic analysis

Tognolini, Angela R., Liu, Xin, Pandey, Saurabh, Roberts, Jason A., Wallis, Steven C., Jackson, Dwane and Eley, Victoria A. (2025). Dosing optimisation of intravenous lidocaine in patients with class 1–3 obesity by population pharmacokinetic analysis. Anaesthesia, 80 (5), 511-521. doi: 10.1111/anae.16531

Dosing optimisation of intravenous lidocaine in patients with class 1–3 obesity by population pharmacokinetic analysis

2025

Journal Article

Rezafungin acetate for the treatment of candidemia and invasive candidiasis: a pharmacokinetic evaluation

Bassetti, Matteo, Stewart, Adam, Bartalucci, Claudia, Vena, Antonio, Giacobbe, Daniele Roberto and Roberts, Jason (2025). Rezafungin acetate for the treatment of candidemia and invasive candidiasis: a pharmacokinetic evaluation. Expert Opinion On Drug Metabolism and Toxicology, 21 (2), 125-132. doi: 10.1080/17425255.2024.2424899

Rezafungin acetate for the treatment of candidemia and invasive candidiasis: a pharmacokinetic evaluation

2025

Journal Article

Nebulized aminoglycosides for ventilator-associated pneumonia: methodological considerations and lessons from experimental studies

Rouby, Jean-Jacques, Xia, Jing, Dhanani, Jayesh, Bassi, Gianluigi Li, Monsel, Antoine, Torres, Antoni, Arvaniti, Kostoula, Assefi, Mona, Bassetti, Matteo, Blot, Stijn, Boisson, Matthieu, Bouglé, Adrien, Constantin, Jean-Michel, Dimopoulos, George, Dugernier, Jonathan, Dureau, Pauline, Ehrmann, Stephan, Felton, Timothy, Kollef, Marin, Koutsoukou, Antonia, Kyriakoudi, Anna, Laterre, Pierre-François, Leone, Marc, Lepère, Victoria, Liao, Xuelian, Mishra, Shakti Bedanta, Mimoz, Olivier, Nair, Girish B, Niederman, Michael ... Zhu, Ying-gang (2025). Nebulized aminoglycosides for ventilator-associated pneumonia: methodological considerations and lessons from experimental studies. Journal of Intensive Medicine, 5 (1), 12-22. doi: 10.1016/j.jointm.2024.07.006

Nebulized aminoglycosides for ventilator-associated pneumonia: methodological considerations and lessons from experimental studies

2025

Journal Article

Development of Methods to Produce SARS CoV-2 Virus-Like Particles at Scale

Edeling, Melissa A., Earnest, Linda, Carrera Montoya, Julio, Yap, Ashley Huey Yiing, Mumford, Jamie, Roberts, Jason, Wong, Chinn Yi, Hans, Dhiraj, Grima, Joseph, Bisset, Nicole, Bodle, Jesse, Rockman, Steven and Torresi, Joseph (2025). Development of Methods to Produce SARS CoV-2 Virus-Like Particles at Scale. Biotechnology and Bioengineering, 122 (5), 1118-1129. doi: 10.1002/bit.28937

Development of Methods to Produce SARS CoV-2 Virus-Like Particles at Scale