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2024

Journal Article

Can capillary microsampling facilitate a clinical pharmacokinetics study of cefazolin in critically ill children?

Dorofaeff, Tavey, Valero, Yarmarly Guerra, Coulthard, Mark G., Wallis, Steven C., Chatfield, Mark D., Lister, Paula, Lipman, Jeffrey, Roberts, Jason A. and Parker, Suzanne L. (2024). Can capillary microsampling facilitate a clinical pharmacokinetics study of cefazolin in critically ill children?. Bioanalysis, 16 (16), 873-881. doi: 10.1080/17576180.2024.2377912

Can capillary microsampling facilitate a clinical pharmacokinetics study of cefazolin in critically ill children?

2024

Journal Article

Continuous vs intermittent β-lactam antibiotic infusions in critically ill patients with sepsis : The BLING III Randomized Clinical Trial

Dulhunty, Joel M., Brett, Stephen J., De Waele, Jan J., Rajbhandari, Dorrilyn, Billot, Laurent, Cotta, Menino O., Davis, Joshua S., Finfer, Simon, Hammond, Naomi E., Knowles, Serena, Liu, Xiaoqiu, McGuinness, Shay, Mysore, Jayanthi, Paterson, David L., Peake, Sandra, Rhodes, Andrew, Roberts, Jason A., Roger, Claire, Shirwadkar, Charudatt, Starr, Therese, Taylor, Colman, Myburgh, John A., Lipman, Jeffrey, Bellomo, Rinaldo, Eastwood, Glenn, Peck, Leah, Young, Helen, Cheng, Andrew, Lau, Luke ... for the BLING III Study Investigators (2024). Continuous vs intermittent β-lactam antibiotic infusions in critically ill patients with sepsis : The BLING III Randomized Clinical Trial. JAMA, 332 (8), 629-637. doi: 10.1001/jama.2024.9779

Continuous vs intermittent β-lactam antibiotic infusions in critically ill patients with sepsis : The BLING III Randomized Clinical Trial

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2024

Journal Article

Prolonged vs intermittent infusions of β-lactam antibiotics in adults with sepsis or septic shock: a systematic review and meta-analysis

Abdul-Aziz, Mohd H., Hammond, Naomi E., Brett, Stephen J., Cotta, Menino O., De Waele, Jan J., Devaux, Anthony, Di Tanna, Gian Luca, Dulhunty, Joel M., Elkady, Hatem, Eriksson, Lars, Hasan, M Shahnaz, Khan, Ayesha Bibi, Lipman, Jeffrey, Liu, Xiaoqiu, Monti, Giacomo, Myburgh, John, Novy, Emmanuel, Omar, Shahed, Rajbhandari, Dorrilyn, Roger, Claire, Sjövall, Fredrik, Zaghi, Irene, Zangrillo, Alberto, Delaney, Anthony and Roberts, Jason A. (2024). Prolonged vs intermittent infusions of β-lactam antibiotics in adults with sepsis or septic shock: a systematic review and meta-analysis. JAMA, 332 (8), 638-648. doi: 10.1001/jama.2024.9803

Prolonged vs intermittent infusions of β-lactam antibiotics in adults with sepsis or septic shock: a systematic review and meta-analysis

2024

Journal Article

Clinical guidance for unfractionated heparin dosing and monitoring in critically ill patients

Samimi, May N., Hale, Andrew, Schults, Jessica, Fischer, Andreas, Roberts, Jason A. and Dhanani, Jayesh (2024). Clinical guidance for unfractionated heparin dosing and monitoring in critically ill patients. Expert Opinion on Pharmacotherapy, 25 (8), 985-997. doi: 10.1080/14656566.2024.2364057

Clinical guidance for unfractionated heparin dosing and monitoring in critically ill patients

2024

Journal Article

Current practices and challenges of outpatient parenteral antimicrobial therapy: a narrative review

Wolie, Zenaw T., Roberts, Jason A., Gilchrist, Mark, McCarthy, Kate and Sime, Fekade B. (2024). Current practices and challenges of outpatient parenteral antimicrobial therapy: a narrative review. Journal of Antimicrobial Chemotherapy, 79 (9), 2083-2102. doi: 10.1093/jac/dkae177

Current practices and challenges of outpatient parenteral antimicrobial therapy: a narrative review

2024

Journal Article

TMPRSS2 inhibitors for the treatment of COVID-19 in adults: a systematic review and meta-analysis of randomized clinical trials of nafamostat and camostat mesylate

Hernández-Mitre, María Patricia, Morpeth, Susan C., Venkatesh, Balasubramanian, Hills, Thomas E., Davis, Joshua, Mahar, Robert K., McPhee, Grace, Jones, Mark, Totterdell, James, Tong, Steven Y. C. and Roberts, Jason A. (2024). TMPRSS2 inhibitors for the treatment of COVID-19 in adults: a systematic review and meta-analysis of randomized clinical trials of nafamostat and camostat mesylate. Clinical Microbiology and Infection, 30 (6), 743-754. doi: 10.1016/j.cmi.2024.01.029

TMPRSS2 inhibitors for the treatment of COVID-19 in adults: a systematic review and meta-analysis of randomized clinical trials of nafamostat and camostat mesylate

2024

Journal Article

Population pharmacokinetics of prophylactic cefoxitin in elective bariatric surgery patients: a prospective monocentric study

Novy, Emmanuel, Liu, Xin, Hernandez-Mitre, Maria Patricia, Belveyre, Thibaut, Scala-Bertola, Julien, Roberts, Jason A. and Parker, Suzanne L. (2024). Population pharmacokinetics of prophylactic cefoxitin in elective bariatric surgery patients: a prospective monocentric study. Anaesthesia Critical Care and Pain Medicine, 43 (3) 101376, 1-8. doi: 10.1016/j.accpm.2024.101376

Population pharmacokinetics of prophylactic cefoxitin in elective bariatric surgery patients: a prospective monocentric study

2024

Journal Article

COVID-19 drug treatments are prone to sequestration in extracorporeal membrane oxygenation circuits: an ex vivo extracorporeal membrane oxygenation study

Dhanani, Jayesh A., Shekar, Kiran, Parmar, Dinesh, Lipman, Jeffrey, Bristow, Debra, Wallis, Steven C., Won, Hayoung, Sumi, Chandra D., Abdul-Aziz, Mohd H. and Roberts, Jason A. (2024). COVID-19 drug treatments are prone to sequestration in extracorporeal membrane oxygenation circuits: an ex vivo extracorporeal membrane oxygenation study. ASAIO Journal, 70 (6), 546-552. doi: 10.1097/MAT.0000000000002120

COVID-19 drug treatments are prone to sequestration in extracorporeal membrane oxygenation circuits: an ex vivo extracorporeal membrane oxygenation study

2024

Journal Article

Pooled population pharmacokinetic analysis and dose recommendations for ciprofloxacin in intensive care unit patients with obesity

van Rhee, Koen P., Brüggemann, Roger J.M., Roberts, Jason A., Sjövall, Fredrik, van Hest, Reinier M., Elbers, Paul W.G., Abdulla, Alan, van der Linden, Paul D. and Knibbe, Catherijne A.J. (2024). Pooled population pharmacokinetic analysis and dose recommendations for ciprofloxacin in intensive care unit patients with obesity. The Journal of Clinical Pharmacology, 64 (9), 1165-1172. doi: 10.1002/jcph.2450

Pooled population pharmacokinetic analysis and dose recommendations for ciprofloxacin in intensive care unit patients with obesity

2024

Journal Article

Nimodipine prophylaxis in aneurysmal subarachnoid hemorrhage, a question of tradition or evidence: A scoping review

Bellapart, Judith, Laupland, Kevin B., Malacova, Eva, Roberts, Jason A. and Paratz, Jennifer (2024). Nimodipine prophylaxis in aneurysmal subarachnoid hemorrhage, a question of tradition or evidence: A scoping review. Journal of Clinical Neuroscience, 123, 91-99. doi: 10.1016/j.jocn.2024.03.016

Nimodipine prophylaxis in aneurysmal subarachnoid hemorrhage, a question of tradition or evidence: A scoping review

2024

Journal Article

Correction: achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsis

Chai, Ming G., Tu, Quyen, Cotta, Menino O., Bauer, Michelle J., Balch, Ross, Okafor, Charles, Comans, Tracy, Kruger, Peter, Meyer, Jason, Shekar, Kiran, Brady, Kara, Fourie, Cheryl, Sharp, Natalie, Vlad, Luminita, Whiley, David, Ungerer, Jacobus P. J., Mcwhinney, Brett C., Farkas, Andras, Paterson, David L., Clark, Julia E., Hajkowicz, Krispin, Raman, Sainath, Bialasiewicz, Seweryn, Lipman, Jeffrey, Forde, Brian M., Harris, Patrick N. A., Schlapbach, Luregn J., Coin, Lachlan, Roberts, Jason A. and Irwin, Adam D. (2024). Correction: achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsis. Intensive Care Medicine, 50 (5), 810-810. doi: 10.1007/s00134-024-07393-9

Correction: achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsis

2024

Journal Article

Evaluation of the stability of ceftazidime/avibactam in elastomeric infusion devices used for outpatient parenteral antimicrobial therapy utilizing a national stability protocol framework

Naicker, Saiyuri, Roberts, Jason A., Won, Hayoung, Wallis, Steven C., Unwin, Sean, Jamieson, Conor, Hills, Tim, Gilchrist, Mark, Santillo, Mark, Seaton, R. Andrew, Drummond, Felicity and Sime, Fekade B. (2024). Evaluation of the stability of ceftazidime/avibactam in elastomeric infusion devices used for outpatient parenteral antimicrobial therapy utilizing a national stability protocol framework. JAC-Antimicrobial Resistance, 6 (2) dlae056, 1-10. doi: 10.1093/jacamr/dlae056

Evaluation of the stability of ceftazidime/avibactam in elastomeric infusion devices used for outpatient parenteral antimicrobial therapy utilizing a national stability protocol framework

2024

Journal Article

Achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsis

Chai, Gene G., Tu, Quyen, Cotta, Menino O., Bauer, Michelle J., Balch, Ross, Okafor, Charles, Comans, Tracy, Kruger, Peter, Meyer, Jason, Shekar, Kiran, Brady, Kara, Fourie, Cheryl, Sharp, Natalie, Vlad, Luminita, Whiley, David, Ungerer, Jacobus P. J., McWhinney, Brett C., Farkas, Andras, Paterson, David L., Clark, Julia E., Hajkowicz, Krispin, Raman, Sainath, Bialasiewicz, Seweryn, Lipman, Jeffrey, Forde, Brian M., Harris, Patrick N. A., Schlapbach, Luregn J., Coin, Lachlan, Roberts, Jason A. and Irwin, Adam D. (2024). Achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsis. Intensive Care Medicine, 50 (4), 539-547. doi: 10.1007/s00134-024-07353-3

Achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsis

2024

Journal Article

What are the optimal pharmacokinetic/pharmacodynamic targets for β-lactamase inhibitors? A systematic review

Assefa, Getnet M, Roberts, Jason A, Mohammed, Solomon A and Sime, Fekade B (2024). What are the optimal pharmacokinetic/pharmacodynamic targets for β-lactamase inhibitors? A systematic review. Journal of Antimicrobial Chemotherapy, 79 (5) dkae058, 946-958. doi: 10.1093/jac/dkae058

What are the optimal pharmacokinetic/pharmacodynamic targets for β-lactamase inhibitors? A systematic review

2024

Journal Article

Factors Influencing Integration and Usability of Model-Informed Precision Dosing Software in the Intensive Care Unit

Chai, Ming G., Roberts, Natasha A., Dobbins, Chelsea, Roberts, Jason A. and Cotta, Menino O. (2024). Factors Influencing Integration and Usability of Model-Informed Precision Dosing Software in the Intensive Care Unit. Applied Clinical Informatics, 15 (2), 388-396. doi: 10.1055/s-0044-1786978

Factors Influencing Integration and Usability of Model-Informed Precision Dosing Software in the Intensive Care Unit

2024

Journal Article

Population pharmacokinetics of posaconazole in allogeneic haematopoietic stem cell transplant patients

Selby, Philip R., Heffernan, Aaron J., Yeung, David, Warner, Morgyn S., Peake, Sandra L., Hahn, Uwe, Westley, Ian, Shakib, Sepehr and Roberts, Jason A. (2024). Population pharmacokinetics of posaconazole in allogeneic haematopoietic stem cell transplant patients. Journal of Antimicrobial Chemotherapy, 79 (3), 567-577. doi: 10.1093/jac/dkae006

Population pharmacokinetics of posaconazole in allogeneic haematopoietic stem cell transplant patients

2024

Journal Article

Understanding the nebulisation of antibiotics: the key role of lung microdialysis studies

Dhanani, Jayesh, Roberts, Jason A., Monsel, Antoine, Torres, Antoni, Kollef, Marin, Rouby, Jean-Jacques, Arvaniti, Kostoula, Assefi, Mona, Bassetti, Matteo, Blot, Stijn, Boisson, Matthieu, Bouglé, Adrien, Constantin, Jean-Michel, Dhanani, Jayesh, Dimopoulos, George, Dugernier, Jonathan, Dureau, Pauline, Felton, Timothy, Kollef, Marin, Koutsoukou, Antonia, Kyriakoudi, Anna, Laterre, Pierre-François, Leone, Marc, Lepère, Victoria, Bassi, Gianluigi Li, Liao, Xuelian, Mimoz, Olivier, Monsel, Antoine, Nair, Girish B. ... the European Investigators Network for Nebulized Antibiotics in Ventilator-associated Pneumonia (2024). Understanding the nebulisation of antibiotics: the key role of lung microdialysis studies. Critical Care, 28 (1) 49, 49. doi: 10.1186/s13054-024-04828-z

Understanding the nebulisation of antibiotics: the key role of lung microdialysis studies

2024

Journal Article

The global epidemiology of ventilator-associated pneumonia caused by multi-drug resistant Pseudomonas aeruginosa: a systematic review and meta-analysis

Li, Yixuan, Roberts, Jason A., Walker, Mikaela M., Aslan, Abdullah Tarik, Harris, Patrick N. A. and Sime, Fekade (2024). The global epidemiology of ventilator-associated pneumonia caused by multi-drug resistant Pseudomonas aeruginosa: a systematic review and meta-analysis. International Journal of Infectious Diseases, 139, 78-85. doi: 10.1016/j.ijid.2023.11.023

The global epidemiology of ventilator-associated pneumonia caused by multi-drug resistant Pseudomonas aeruginosa: a systematic review and meta-analysis

2024

Journal Article

Population pharmacokinetics and dosing simulations of total and unbound temocillin in the plasma and CSF of neurocritically ill patients with external ventricular drain-related cerebral ventriculitis

Ngougni Pokem, Perrin, Liu, Xin, Parker, Suzanne L., Verroken, Alexia, Collienne, Christine, Finet, Patrice, Wijnant, Gert-Jan, Laterre, Pierre-François, Roberts, Jason A., Van Bambeke, Françoise and Wittebole, Xavier (2024). Population pharmacokinetics and dosing simulations of total and unbound temocillin in the plasma and CSF of neurocritically ill patients with external ventricular drain-related cerebral ventriculitis. Journal of Antimicrobial Chemotherapy, 79 (2), 429-442. doi: 10.1093/jac/dkad398

Population pharmacokinetics and dosing simulations of total and unbound temocillin in the plasma and CSF of neurocritically ill patients with external ventricular drain-related cerebral ventriculitis

2024

Journal Article

Estimation of kidney function for medication dosing in adult patients with chronic kidney disease: a practice update

Mirkov, Sanja, Scuderi, Carla, Lloyd, Jess, Coutsouvelis, John, O'Connor, Shaun, Potts, Simon, Newman, Suzanne and Roberts, Jason (2024). Estimation of kidney function for medication dosing in adult patients with chronic kidney disease: a practice update. Journal of Pharmacy Practice and Research, 54 (1), 94-106. doi: 10.1002/jppr.1884

Estimation of kidney function for medication dosing in adult patients with chronic kidney disease: a practice update