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2024

Journal Article

Estimation of kidney function for medication dosing in adult patients with chronic kidney disease: a practice update

Mirkov, Sanja, Scuderi, Carla, Lloyd, Jess, Coutsouvelis, John, O'Connor, Shaun, Potts, Simon, Newman, Suzanne and Roberts, Jason (2024). Estimation of kidney function for medication dosing in adult patients with chronic kidney disease: a practice update. Journal of Pharmacy Practice and Research, 54 (1), 94-106. doi: 10.1002/jppr.1884

Estimation of kidney function for medication dosing in adult patients with chronic kidney disease: a practice update

2024

Journal Article

Population pharmacokinetics and dosing simulations of total and unbound temocillin in the plasma and CSF of neurocritically ill patients with external ventricular drain-related cerebral ventriculitis

Ngougni Pokem, Perrin, Liu, Xin, Parker, Suzanne L., Verroken, Alexia, Collienne, Christine, Finet, Patrice, Wijnant, Gert-Jan, Laterre, Pierre-François, Roberts, Jason A., Van Bambeke, Françoise and Wittebole, Xavier (2024). Population pharmacokinetics and dosing simulations of total and unbound temocillin in the plasma and CSF of neurocritically ill patients with external ventricular drain-related cerebral ventriculitis. Journal of Antimicrobial Chemotherapy, 79 (2), 429-442. doi: 10.1093/jac/dkad398

Population pharmacokinetics and dosing simulations of total and unbound temocillin in the plasma and CSF of neurocritically ill patients with external ventricular drain-related cerebral ventriculitis

2024

Journal Article

Rapid nanopore sequencing and predictive susceptibility testing of positive blood cultures from intensive care patients with sepsis

Harris, Patrick N. A., Bauer, Michelle J., Lüftinger, Lukas, Beisken, Stephan, Forde, Brian M., Balch, Ross, Cotta, Menino, Schlapbach, Luregn, Raman, Sainath, Shekar, Kiran, Kruger, Peter, Lipman, Jeff, Bialasiewicz, Seweryn, Coin, Lachlan, Roberts, Jason A., Paterson, David L. and Irwin, Adam D. (2024). Rapid nanopore sequencing and predictive susceptibility testing of positive blood cultures from intensive care patients with sepsis. Microbiology Spectrum, 12 (2) e0306523, 1-16. doi: 10.1128/spectrum.03065-23

Rapid nanopore sequencing and predictive susceptibility testing of positive blood cultures from intensive care patients with sepsis

2024

Journal Article

The pharmacokinetics of ganciclovir during prolonged intermittent kidney replacement therapy in a cardiac transplant recipient

Carter, B., Salman, S., Rawlins, M. D. M., Allen, C. T., Morgan, D. J., Boan, P. and Roberts, J. A. (2024). The pharmacokinetics of ganciclovir during prolonged intermittent kidney replacement therapy in a cardiac transplant recipient. Journal of Chemotherapy, 1-4. doi: 10.1080/1120009X.2024.2395776

The pharmacokinetics of ganciclovir during prolonged intermittent kidney replacement therapy in a cardiac transplant recipient

2024

Journal Article

Antibiotic dose optimisation in the critically ill: targets, evidence and future strategies

Dyer, Christopher J., De Waele, Jan J. and Roberts, Jason A. (2024). Antibiotic dose optimisation in the critically ill: targets, evidence and future strategies. Current Opinion in Critical Care, 30 (5), 439-447. doi: 10.1097/MCC.0000000000001187

Antibiotic dose optimisation in the critically ill: targets, evidence and future strategies

2024

Journal Article

Effect of two hydration strategies on CapillarySodium concentrations in runners participating in 170-km trail race: The 2015 UltraTrail du Mont-Blanc experience

Coulomb, Rémy, Basset, Patrick, Mezzarobba, Myriam, Masseguin, Christophe, Lefrant, Jean-Yves, Mura, Thibault, Roberts, Jason A. and Mares, Olivier (2024). Effect of two hydration strategies on CapillarySodium concentrations in runners participating in 170-km trail race: The 2015 UltraTrail du Mont-Blanc experience. Clinical Journal of Sport Medicine. doi: 10.1097/JSM.0000000000001266

Effect of two hydration strategies on CapillarySodium concentrations in runners participating in 170-km trail race: The 2015 UltraTrail du Mont-Blanc experience

2023

Journal Article

Population pharmacokinetics of fluconazole in critically ill patients receiving extracorporeal membrane oxygenation and continuous renal replacement therapy: an ASAP ECMO study

Novy, Emmanuel, Abdul-Aziz, Mohd H., Cheng, Vesa, Burrows, Fay, Buscher, Hergen, Corley, Amanda, Diehl, Arne, Gilder, Eileen, Levkovich, Bianca J., McGuinness, Shay, Ordonez, Jenny, Parke, Rachael, Parker, Suzanne, Pellegrino, Vincent, Reynolds, Claire, Rudham, Sam, Wallis, Steven C., Welch, Susan A., Fraser, John F., Shekar, Kiran and Roberts, Jason A. (2023). Population pharmacokinetics of fluconazole in critically ill patients receiving extracorporeal membrane oxygenation and continuous renal replacement therapy: an ASAP ECMO study. Antimicrobial Agents and Chemotherapy, 68 (1) e0120123, e0120123. doi: 10.1128/aac.01201-23

Population pharmacokinetics of fluconazole in critically ill patients receiving extracorporeal membrane oxygenation and continuous renal replacement therapy: an ASAP ECMO study

2023

Journal Article

A phase I, randomized, double-blind, placebo-controlled, ascending single- and multiple-dose study of the pharmacokinetics, safety, and tolerability of oral ceftibuten in healthy adult subjects

Hernández-Mitre, María Patricia, Wallis, Steven C., Morgan, Elizabeth E., Dudley, Michael N., Loutit, Jeffery S., Griffith, David C. and Roberts, Jason A. (2023). A phase I, randomized, double-blind, placebo-controlled, ascending single- and multiple-dose study of the pharmacokinetics, safety, and tolerability of oral ceftibuten in healthy adult subjects. Antimicrobial Agents and Chemotherapy, 68 (1) e0109923, 1-12. doi: 10.1128/aac.01099-23

A phase I, randomized, double-blind, placebo-controlled, ascending single- and multiple-dose study of the pharmacokinetics, safety, and tolerability of oral ceftibuten in healthy adult subjects

2023

Journal Article

Efficiency of dosing software using Bayesian forecasting in achieving target antibiotic exposures in critically ill patients, a prospective cohort study

Chai, Ming G., Roberts, Jason A., Kelly, Christina F., Ungerer, Jacobus P.J., McWhinney, Brett C., Lipman, Jeffrey, Farkas, Andras and Cotta, Menino O. (2023). Efficiency of dosing software using Bayesian forecasting in achieving target antibiotic exposures in critically ill patients, a prospective cohort study. Anaesthesia Critical Care and Pain Medicine, 42 (6) 101296, 101296. doi: 10.1016/j.accpm.2023.101296

Efficiency of dosing software using Bayesian forecasting in achieving target antibiotic exposures in critically ill patients, a prospective cohort study

2023

Journal Article

AUC-based monitoring and model-informed precision dosing of vancomycin in critically ill patients: why and how?

Goutelle, Sylvain, Wallet, Florent, Thoma, Yann, Peclard, Jean-Rémi, Bourguignon, Laurent, Cohen, Sabine, Kipnis, Eric, Roberts, Jason, Allaouchiche, Bernard and Friggeri, Arnaud (2023). AUC-based monitoring and model-informed precision dosing of vancomycin in critically ill patients: why and how?. Anaesthesia Critical Care and Pain Medicine, 42 (6) 101286, 1-4. doi: 10.1016/j.accpm.2023.101286

AUC-based monitoring and model-informed precision dosing of vancomycin in critically ill patients: why and how?

2023

Journal Article

Comment: Is off-label medication use in the ICU a problem?

Cotta, Menino O., Roberts, Jason A. and Reade, Michael C. (2023). Comment: Is off-label medication use in the ICU a problem?. Critical Care, 27 (1) 288, 288. doi: 10.1186/s13054-023-04546-y

Comment: Is off-label medication use in the ICU a problem?

2023

Journal Article

Real-world experience of therapeutic drug monitoring and PK/PD achievement of ceftaroline administered by different infusion regimens in patients with confirmed infections caused by Gram-positive bacteria

Fresán, Daniel, Luque, Sonia, Benítez-Cano, Adela, Sorlí, Luisa, Montero, María Milagro, De-Antonio, Marta, Vega, Victoria, Roberts, Jason A., Horcajada, Juan P. and Grau, Santiago (2023). Real-world experience of therapeutic drug monitoring and PK/PD achievement of ceftaroline administered by different infusion regimens in patients with confirmed infections caused by Gram-positive bacteria. Journal of Antimicrobial Chemotherapy, 78 (12), 2810-2815. doi: 10.1093/jac/dkad296

Real-world experience of therapeutic drug monitoring and PK/PD achievement of ceftaroline administered by different infusion regimens in patients with confirmed infections caused by Gram-positive bacteria

2023

Journal Article

Flattening the biological age curve by improving metabolic health: to taurine or not to taurine, that’ s the question

Ho, Kwok M., Lee, Anna, Wu, William, Chan, Matthew T. V., Ling, Lowell, Lipman, Jeffrey, Roberts, Jason, Litton, Edward, Joynt, Gavin M. and Wong, Martin (2023). Flattening the biological age curve by improving metabolic health: to taurine or not to taurine, that’ s the question. Journal of Geriatric Cardiology, 20 (11), 813-823. doi: 10.26599/1671-5411.2023.11.004

Flattening the biological age curve by improving metabolic health: to taurine or not to taurine, that’ s the question

2023

Journal Article

Pharmacokinetic and pharmacodynamic considerations for antifungal therapy optimisation in the treatment of intra-abdominal candidiasis

Novy, Emmanuel, Roger, Claire, Roberts, Jason A. and Cotta, Menino Osbert (2023). Pharmacokinetic and pharmacodynamic considerations for antifungal therapy optimisation in the treatment of intra-abdominal candidiasis. Critical Care, 27 (1) 449, 1-17. doi: 10.1186/s13054-023-04742-w

Pharmacokinetic and pharmacodynamic considerations for antifungal therapy optimisation in the treatment of intra-abdominal candidiasis

2023

Journal Article

Performance of different body weights in the Cockcroft‐Gault equation in critically ill patients with and without augmented renal clearance: a multicenter cohort

Cucci, Michaelia D., Gerlach, Anthony T., Mangira, Caroline, Murphy, Claire V., Roberts, Jason A., Udy, Andrew A., Dowling, Thomas C. and Mullen, Chanda L. (2023). Performance of different body weights in the Cockcroft‐Gault equation in critically ill patients with and without augmented renal clearance: a multicenter cohort. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 43 (11), 1131-1138. doi: 10.1002/phar.2743

Performance of different body weights in the Cockcroft‐Gault equation in critically ill patients with and without augmented renal clearance: a multicenter cohort

2023

Journal Article

In silico evaluation of a beta‐lactam dosing guideline among adults with serious infections

Williams, Paul, Cotta, Menino Osbert, Abdul‐Aziz, Mohd H., Wilks, Kathryn, Farkas, Andras and Roberts, Jason A. (2023). In silico evaluation of a beta‐lactam dosing guideline among adults with serious infections. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 43 (11), 1121-1130. doi: 10.1002/phar.2753

In silico evaluation of a beta‐lactam dosing guideline among adults with serious infections

2023

Journal Article

Early oral antibiotic switch in Staphylococcus aureus bacteraemia: The Staphylococcus aureus Network Adaptive Platform (SNAP) Trial Early Oral Switch Protocol

de Kretser, Dana, Mora, Jocelyn, Bloomfield, Max, Campbell, Anita, Cheng, Matthew P., Guy, Stephen, Hensgens, Marjolein, Kalimuddin, Shirin, Lee, Todd C., Legg, Amy, Mahar, Robert K., Marks, Michael, Marsh, Julie, Mcglothin, Anna, Morpeth, Susan C., Sud, Archana, Ten Oever, Jaap, Yahav, Dafna, Bonten, Marc, Bowen, Asha C., Daneman, Nick, van Hal, Sebastiaan J., Heriot, George S., Lewis, Roger J., Lye, David C., Mcquilten, Zoe, Paterson, David L., Owen Robinson, J., Roberts, Jason A. ... Goodman, Anna L. (2023). Early oral antibiotic switch in Staphylococcus aureus bacteraemia: The Staphylococcus aureus Network Adaptive Platform (SNAP) Trial Early Oral Switch Protocol. Clinical Infectious Diseases, 79 (4), 871-887. doi: 10.1093/cid/ciad666

Early oral antibiotic switch in Staphylococcus aureus bacteraemia: The Staphylococcus aureus Network Adaptive Platform (SNAP) Trial Early Oral Switch Protocol

2023

Journal Article

A randomized trial of Nafamostat for Covid-19

Morpeth, Susan C., Venkatesh, Balasubramanian, Totterdell, James A., McPhee, Grace M., Mahar, Robert K., Jones, Mark, Bandara, Methma, Barina, Lauren A., Basnet, Bhupendra K., Bowen, Asha C., Burke, Andrew J., Cochrane, Belinda, Denholm, Justin T., Dhungana, Ashesh, Dore, Gregory J., Dotel, Ravindra, Duffy, Eamon, Dummer, Jack, Foo, Hong, Gilbey, Timothy L., Hammond, Naomi E., Hudson, Bernard J., Jha, Vivekanand, Jevaji, Purnima R., John, Oommen, Joshi, Rajesh, Kang, Gagandeep, Kaur, Baldeep, Kim, Seungtaek ... Tong, Steven Y.C. (2023). A randomized trial of Nafamostat for Covid-19. NEJM Evidence, 2 (11), EVIDoa2300132. doi: 10.1056/evidoa2300132

A randomized trial of Nafamostat for Covid-19

2023

Journal Article

Avoiding misclassification of acute kidney injury: timing is everything

Legg, Amy, Roberts, Jason A., Roberts, Matthew A., Cass, Alan, Davies, Jane, Tong, Steven Y. C. and Davis, Joshua S. (2023). Avoiding misclassification of acute kidney injury: timing is everything. Nephrology, 29 (2), 100-104. doi: 10.1111/nep.14246

Avoiding misclassification of acute kidney injury: timing is everything

2023

Journal Article

In vitro susceptibility testing of imipenem- relebactam and tedizolid against 102 Mycobacterium abscessus isolates

Burke, Andrew, Carter, Robyn, Tolson, Carla, Congdon, Jacob, Duplancic, Christine, Bursle, Evan, Bell, Scott C., Roberts, Jason A. and Thomson, Rachel (2023). In vitro susceptibility testing of imipenem- relebactam and tedizolid against 102 Mycobacterium abscessus isolates. International Journal of Antimicrobial Agents, 62 (4) 106938, 1-6. doi: 10.1016/j.ijantimicag.2023.106938

In vitro susceptibility testing of imipenem- relebactam and tedizolid against 102 Mycobacterium abscessus isolates