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2024 Journal Article Sulfated bile acid is a host-derived ligand for MAIT cellsIto, Emi, Inuki, Shinsuke, Izumi, Yoshihiro, Takahashi, Masatomo, Dambayashi, Yuki, Ciacchi, Lisa, Awad, Wael, Takeyama, Ami, Shibata, Kensuke, Mori, Shotaro, Mak, Jeffrey Y. W., Fairlie, David P., Bamba, Takeshi, Ishikawa, Eri, Nagae, Masamichi, Rossjohn, Jamie and Yamasaki, Sho (2024). Sulfated bile acid is a host-derived ligand for MAIT cells. Science Immunology, 9 (91) eade6924, eade6924. doi: 10.1126/sciimmunol.ade6924 |
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2023 Journal Article Synthetic 5-amino-6-D-ribitylaminouracil paired with inflammatory stimuli facilitates MAIT cell expansion in vivoNelson, Adam G., Wang, Huimeng, Dewar, Phoebe M., Eddy, Eleanor M., Li, Songyi, Lim, Xin Yi, Patton, Timothy, Zhou, Yuchen, Pediongco, Troi J., Meehan, Lucy J., Meehan, Bronwyn S., Mak, Jeffrey Y. W., Fairlie, David P., Stent, Andrew W., Kjer-Nielsen, Lars, McCluskey, James, Eckle, Sidonia B. G., Corbett, Alexandra J., Souter, Michael N. T. and Chen, Zhenjun (2023). Synthetic 5-amino-6-D-ribitylaminouracil paired with inflammatory stimuli facilitates MAIT cell expansion in vivo. Frontiers in Immunology, 14 1109759, 1-15. doi: 10.3389/fimmu.2023.1109759 |
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2023 Journal Article Histone deacetylase 7: a signalling hub controlling development, inflammation, metabolism and diseaseWang, Yizhuo, Abrol, Rishika, Mak, Jeffrey Y. W., Das Gupta, Kaustav, Ramnath, Divya, Karunakaran, Denuja, Fairlie, David P. and Sweet, Matthew J. (2023). Histone deacetylase 7: a signalling hub controlling development, inflammation, metabolism and disease. The FEBS Journal, 290 (11), 2805-2832. doi: 10.1111/febs.16437 |
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2022 Journal Article Quantitative affinity measurement of small molecule ligand binding to Major Histocompatibility Complex class-I related protein 1 MR1Wang, Carl J.H., Awad, Wael, Liu, Ligong, Mak, Jeffrey Y.W., Veerapen, Natacha, Illing, Patricia T., Purcell, Anthony W., Eckle, Sidonia B.G., McCluskey, James, Besra, Gurdyal S., Fairlie, David P., Rossjohn, Jamie and Le Nours, Jérôme (2022). Quantitative affinity measurement of small molecule ligand binding to Major Histocompatibility Complex class-I related protein 1 MR1. Journal of Biological Chemistry, 298 (12) 102714, 1-12. doi: 10.1016/j.jbc.2022.102714 |
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2022 Journal Article A specialized tyrosine-based endocytosis signal in MR1 controls antigen presentation to MAIT cellsLim, Hui Jing, Wubben, Jacinta M., Garcia, Cristian Pinero, Cruz-Gomez, Sebastian, Deng, Jieru, Mak, Jeffrey Y.W., Hachani, Abderrahman, Anderson, Regan J., Painter, Gavin F., Goyette, Jesse, Amarasinghe, Shanika L., Ritchie, Matthew E., Roquilly, Antoine, Fairlie, David P., Gaus, Katharina, Rossjohn, Jamie, Villadangos, Jose A. and McWilliam, Hamish E.G. (2022). A specialized tyrosine-based endocytosis signal in MR1 controls antigen presentation to MAIT cells. Journal of Cell Biology, 221 (12) e202110125. doi: 10.1083/jcb.202110125 |
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2022 Journal Article CD8 coreceptor engagement of MR1 enhances antigen responsiveness by human MAIT and other MR1-reactive T cellsSouter, Michael N.T., Awad, Wael, Li, Shihan, Pediongco, Troi J., Meehan, Bronwyn S., Meehan, Lucy J., Tian, Zehua, Zhao, Zhe, Wang, Huimeng, Nelson, Adam, Le Nours, Jérôme, Khandokar, Yogesh, Praveena, T., Wubben, Jacinta, Lin, Jie, Sullivan, Lucy C., Lovrecz, George O., Mak, Jeffrey Y.W., Liu, Ligong, Kostenko, Lyudmila, Kedzierska, Katherine, Corbett, Alexandra J., Fairlie, David P., Brooks, Andrew G., Gherardin, Nicholas A., Uldrich, Adam P., Chen, Zhenjun, Rossjohn, Jamie, Godfrey, Dale I. ... Eckle, Sidonia B.G. (2022). CD8 coreceptor engagement of MR1 enhances antigen responsiveness by human MAIT and other MR1-reactive T cells. Journal of Experimental Medicine, 219 (9) e20210828, 1-30. doi: 10.1084/jem.20210828 |
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2022 Journal Article Tuning electrostatic and hydrophobic surfaces of aromatic rings to enhance membrane association and cell uptake of peptidesde Araujo, Aline Dantes, Hoang, Huy N., Lim, Junxian, Mak, Jeffrey and Fairlie, David P. (2022). Tuning electrostatic and hydrophobic surfaces of aromatic rings to enhance membrane association and cell uptake of peptides. Angewandte Chemie International Edition, 61 (29) e202203995, e202203995. doi: 10.1002/anie.202203995 |
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2022 Journal Article The balance of IL ‐12 and IL ‐23 determines the bias of MAIT1 versus MAIT17 responses during bacterial infectionWang, Huimeng, Nelson, Adam G., Wang, Bingjie, Zhao, Zhe, Lim, Xin Yi, Shi, Mai, Meehan, Lucy J., Jia, Xiaoxiao, Kedzierska, Katherine, Meehan, Bronwyn S., Eckle, Sidonia B. G., Souter, Michael N. T., Pediongco, Troi J., Mak, Jeffrey Y. W., Fairlie, David P., McCluskey, James, Wang, Zhongfang, Corbett, Alexandra J. and Chen, Zhenjun (2022). The balance of IL ‐12 and IL ‐23 determines the bias of MAIT1 versus MAIT17 responses during bacterial infection. Immunology & Cell Biology, 100 (7), 547-561. doi: 10.1111/imcb.12556 |
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2022 Journal Article Differential location of NKT and MAIT cells within lymphoid tissueJohnson, Darryl N., Ruan, Zheng, Petley, Emma V., Devi, Sapna, Holz, Lauren E., Uldrich, Adam P., Mak, Jeffrey Y. W., Hor, Jyh Liang, Mueller, Scott N., McCluskey, James, Fairlie, David P., Darcy, Phillip K., Beavis, Paul A., Heath, William R. and Godfrey, Dale I. (2022). Differential location of NKT and MAIT cells within lymphoid tissue. Scientific Reports, 12 (1) 4034, 4034. doi: 10.1038/s41598-022-07704-4 |
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2022 Journal Article Inhibition of the master regulator of Listeria monocytogenes virulence enables bacterial clearance from spacious replication vacuoles in infected macrophagesTran, Thao Thanh, Mathmann, Carmen D., Gatica-Andrades, Marcela, Rollo, Rachel F., Oelker, Melanie, Ljungberg, Johanna K., Nguyen, Tam T. K., Zamoshnikova, Alina, Kummari, Lalith K., Wyer, Orry J. K., Irvine, Katharine M., Melo-Bolívar, Javier, Gross, Annette, Brown, Darren, Mak, Jeffrey Y. W., Fairlie, David P., Hansford, Karl A., Cooper, Matthew A., Giri, Rabina, Schreiber, Veronika, Joseph, Shannon R., Simpson, Fiona, Barnett, Timothy C., Johansson, Jörgen, Dankers, Wendy, Harris, James, Wells, Timothy J., Kapetanovic, Ronan, Sweet, Matthew J. ... Blumenthal, Antje (2022). Inhibition of the master regulator of Listeria monocytogenes virulence enables bacterial clearance from spacious replication vacuoles in infected macrophages. PLoS Pathogens, 18 (1) e1010166, e1010166. doi: 10.1371/journal.ppat.1010166 |
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2021 Journal Article Human MAIT cells respond to and suppress HIV-1Phetsouphanh, Chansavath, Phalora, Prabhjeet, Hackstein, Carl-Philipp, Thornhill, John, Munier, Mee Ling, Meyerowitz, Jodi, Murray, Lyle, VanVuuren, Cloete, Goedhals, Dominique, Drexhage, Linnea, Moore, Rebecca, Sattentau, Quentin J, Mak, Jeffrey YW, Fairlie, David P, Fidler, Sarah, Kelleher, Anthony, Frater, John and Klenerman, Paul (2021). Human MAIT cells respond to and suppress HIV-1. eLife, 10 e50324. doi: 10.7554/elife.50324 |
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2021 Journal Article MAIT cells regulate NK cell-mediated tumor immunityPetley, Emma V., Koay, Hui-Fern, Henderson, Melissa A., Sek, Kevin, Todd, Kirsten L., Keam, Simon P., Lai, Junyun, House, Imran G., Li, Jasmine, Zethoven, Magnus, Chen, Amanda X. Y., Oliver, Amanda J., Michie, Jessica, Freeman, Andrew J., Giuffrida, Lauren, Chan, Jack D., Pizzolla, Angela, Mak, Jeffrey Y. W., McCulloch, Timothy R., Souza-Fonseca-Guimaraes, Fernando, Kearney, Conor J., Millen, Rosemary, Ramsay, Robert G., Huntington, Nicholas D., McCluskey, James, Oliaro, Jane, Fairlie, David P., Neeson, Paul J., Godfrey, Dale I. ... Darcy, Phillip K. (2021). MAIT cells regulate NK cell-mediated tumor immunity. Nature Communications, 12 (1) 4746, 1-15. doi: 10.1038/s41467-021-25009-4 |
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2021 Journal Article Francisella tularensis induces Th1 like MAIT cells conferring protection against systemic and local infectionZhao, Zhe, Wang, Huimeng, Shi, Mai, Zhu, Tianyuan, Pediongco, Troi, Lim, Xin Yi, Meehan, Bronwyn S., Nelson, Adam G., Fairlie, David P., Mak, Jeffrey Y. W., Eckle, Sidonia B. G., de Lima Moreira, Marcela, Tumpach, Carolin, Bramhall, Michael, Williams, Cameron G., Lee, Hyun Jae, Haque, Ashraful, Evrard, Maximilien, Rossjohn, Jamie, McCluskey, James, Corbett, Alexandra J. and Chen, Zhenjun (2021). Francisella tularensis induces Th1 like MAIT cells conferring protection against systemic and local infection. Nature Communications, 12 (1) 4355, 1-15. doi: 10.1038/s41467-021-24570-2 |
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2021 Journal Article Identification and phenotype of MAIT cells in cattle and their response to bacterial infectionsEdmans, Matthew D., Connelley, Timothy K., Jayaraman, Siddharth, Vrettou, Christina, Vordermeier, Martin, Mak, Jeffrey Y. W., Liu, Ligong, Fairlie, David P., Maze, Emmanuel Atangana, Chrun, Tiphany, Klenerman, Paul, Eckle, Sidonia B. G., Tchilian, Elma and Benedictus, Lindert (2021). Identification and phenotype of MAIT cells in cattle and their response to bacterial infections. Frontiers in Immunology, 12 627173, 627173. doi: 10.3389/fimmu.2021.627173 |
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2021 Journal Article Mucosal-associated invariant t cell effector function is an intrinsic cell property that can be augmented by the metabolic cofactor α-ketoglutarateHowson, Lauren J., Li, Jasmine, von Borstel, Anouk, Barugahare, Adele, Mak, Jeffrey Y. W., Fairlie, David P., McCluskey, James, Turner, Stephen J., Davey, Martin S. and Rossjohn, Jamie (2021). Mucosal-associated invariant t cell effector function is an intrinsic cell property that can be augmented by the metabolic cofactor α-ketoglutarate. The Journal of Immunology, 206 (7) ji2001048, 1425-1435. doi: 10.4049/jimmunol.2001048 |
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2021 Journal Article Determination of sample concentrations by PULCON NMR spectroscopyMak, Jeffrey Y. W. (2021). Determination of sample concentrations by PULCON NMR spectroscopy. Australian Journal of Chemistry, 75 (2), 160-164. doi: 10.1071/ch21149 |
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2020 Journal Article MR1-restricted T cells with MAIT-like characteristics are functionally conserved in the Pteropid Bat Pteropus alectoLeeansyah, Edwin, Hey, Ying Ying, Sia, Wan Rong, Ng, Justin Han Jia, Gulam, Muhammad Yaaseen, Boulouis, Caroline, Zhu, Feng, Ahn, Matae, Mak, Jeffrey Y.W., Fairlie, David P., Kwa, Andrea Lay Hoon, Sandberg, Johan K. and Wang, Lin-Fa (2020). MR1-restricted T cells with MAIT-like characteristics are functionally conserved in the Pteropid Bat Pteropus alecto. iScience, 23 (12) 101876, 101876. doi: 10.1016/j.isci.2020.101876 |
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2020 Journal Article Artificially induced MAIT cells inhibit M. bovis BCG but not M. tuberculosis during in vivo pulmonary infectionYu, Huifeng, Yang, Amy, Derrick, Steven, Mak, Jeffrey Y. W., Liu, Ligong, Fairlie, David P. and Cowley, Siobhan (2020). Artificially induced MAIT cells inhibit M. bovis BCG but not M. tuberculosis during in vivo pulmonary infection. Scientific Reports, 10 (1) 13579, 13579. doi: 10.1038/s41598-020-70615-9 |
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2020 Journal Article CXCL16 stimulates antigen-induced MAIT cell accumulation but trafficking during lung infection is CXCR6-independentYu, Huifeng, Yang, Amy, Liu, Ligong, Mak, Jeffrey Y. W., Fairlie, David P. and Cowley, Siobhan (2020). CXCL16 stimulates antigen-induced MAIT cell accumulation but trafficking during lung infection is CXCR6-independent. Frontiers in Immunology, 11 1773, 1773. doi: 10.3389/fimmu.2020.01773 |
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2020 Journal Article Absence of mucosal-associated invariant T cells in a person with a homozygous point mutation in MR1Howson, Lauren J., Awad, Wael, von Borstel, Anouk, Lim, Hui Jing, McWilliam, Hamish E. G., Sandoval-Romero, Maria L., Majumdar, Shamik, Hamzeh, Abdul Rezzak, Andrews, Thomas D., McDermott, David H., Murphy, Philip M., Le Nours, Jérôme, Mak, Jeffrey Y. W., Liu, Ligong, Fairlie, David P., McCluskey, James, Villadangos, Jose A., Cook, Matthew C., Turner, Stephen J., Davey, Martin S., Ojaimi, Samar and Rossjohn, Jamie (2020). Absence of mucosal-associated invariant T cells in a person with a homozygous point mutation in MR1. Science Immunology, 5 (49) 9492, eabc9492. doi: 10.1126/sciimmunol.abc9492 |
