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2024 Journal Article Hi1a improves sensorimotor deficit following endothelin-1-induced stroke in rats but does not improve functional outcomes following filament-induced stroke in miceKnezic, Adriana, Budusan, Elena, Saez, Natalie J., Broughton, Brad R. S., Rash, Lachlan D., King, Glenn F., Widdop, Robert E. and McCarthy, Claudia A. (2024). Hi1a improves sensorimotor deficit following endothelin-1-induced stroke in rats but does not improve functional outcomes following filament-induced stroke in mice. ACS Pharmacology and Translational Science, 7 (4), 1043-1054. doi: 10.1021/acsptsci.3c00328 |
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2024 Book Chapter Targeting acid-sensing ion channels in diseaseSenescall, Victor, Budusan, Elena, Knezic, Adriana, Waqar, Maleeha, Butcher, Neville, Khan, Nemat, McCarthy, Claudia, Widopp, Robert, Karatt-Vellat, Aneesh and Rash, Lachlan D. (2024). Targeting acid-sensing ion channels in disease. Ion channels as targets in drug discovery. (pp. 303-355) edited by Gary Stephens and Edward Stevens. Cham, Switzerland: Springer. doi: 10.1007/978-3-031-52197-3_10 |
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2023 Journal Article The Concise Guide to PHARMACOLOGY 2023/24: Ion channelsAlexander, Stephen P. H., Mathie, Alistair A., Peters, John A., Veale, Emma L., Striessnig, Jörg, Kelly, Eamonn, Armstrong, Jane F., Faccenda, Elena, Harding, Simon D., Davies, Jamie A., Aldrich, Richard W., Attali, Bernard, Baggetta, Austin M., Becirovic, Elvir, Biel, Martin, Bill, Roslyn M., Caceres, Ana I., Catterall, William A., Conner, Alex C., Davies, Paul, De Clerq, Katrien, Delling, Markus, Di Virgilio, Francesco, Falzoni, Simonetta, Fenske, Stefanie, Fortuny‐Gomez, Anna, Fountain, Samuel, George, Chandy, Goldstein, Steve A. N. ... Zhu, Michael (2023). The Concise Guide to PHARMACOLOGY 2023/24: Ion channels. British Journal of Pharmacology, 180 (S2), S145-S222. doi: 10.1111/bph.16178 |
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2023 Journal Article Evaluation of peptide ligation strategies for the synthesis of the bivalent acid-sensing ion channel inhibitor Hi1aTran, Hue N. T., Budusan, Elena, Saez, Natalie J., Norman, Alexander, Tucker, Isaac J., King, Glenn F., Payne, Richard J., Rash, Lachlan D., Vetter, Irina and Schroeder, Christina I. (2023). Evaluation of peptide ligation strategies for the synthesis of the bivalent acid-sensing ion channel inhibitor Hi1a. Organic Letters, 25 (24), 4439-4444. doi: 10.1021/acs.orglett.3c01346 |
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2023 Journal Article Pain-causing stinging nettle toxins target TMEM233 to modulate NaV1.7 functionJami, Sina, Deuis, Jennifer R., Klasfauseweh, Tabea, Cheng, Xiaoyang, Kurdyukov, Sergey, Chung, Felicity, Okorokov, Andrei L., Li, Shengnan, Zhang, Jiangtao, Cristofori-Armstrong, Ben, Israel, Mathilde R., Ju, Robert J., Robinson, Samuel D., Zhao, Peng, Ragnarsson, Lotten, Andersson, Åsa, Tran, Poanna, Schendel, Vanessa, McMahon, Kirsten L., Tran, Hue N. T., Chin, Yanni K.-Y., Zhu, Yifei, Liu, Junyu, Crawford, Theo, Purushothamvasan, Saipriyaa, Habib, Abdella M., Andersson, David A., Rash, Lachlan D., Wood, John N. ... Vetter, Irina (2023). Pain-causing stinging nettle toxins target TMEM233 to modulate NaV1.7 function. Nature Communications, 14 (1) 2442. doi: 10.1038/s41467-023-37963-2 |
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2023 Journal Article Acid-sensing (proton-gated) ion channels (ASICs) in GtoPdb v.2023.1Kellenberger, Stephan and Rash, Lachlan D. (2023). Acid-sensing (proton-gated) ion channels (ASICs) in GtoPdb v.2023.1. IUPHAR/BPS Guide to Pharmacology CITE, 2023 (1). doi: 10.2218/gtopdb/f118/2023.1 |
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2022 Journal Article Multitarget nociceptor sensitization by a promiscuous peptide from the venom of the King Baboon spiderFinol-Urdaneta, Rocio K., Ziegman, Rebekah, Dekan, Zoltan, McArthur, Jeffrey R., Heitmann, Stewart, Luna-Ramirez, Karen, Tae, Han-Shen, Mueller, Alexander, Starobova, Hana, Chin, Yanni K.-Y., Wingerd, Joshua S., Undheim, Eivind A. B., Cristofori-Armstrong, Ben, Hill, Adam P., Herzig, Volker, King, Glenn F., Vetter, Irina, Rash, Lachlan D., Adams, David J. and Alewood, Paul F. (2022). Multitarget nociceptor sensitization by a promiscuous peptide from the venom of the King Baboon spider. Proceedings of the National Academy of Sciences, 119 (5) e2110932119. doi: 10.1073/pnas.2110932119 |
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2021 Journal Article Total synthesis of the spider-venom peptide Hi1aDuggan, Nisharnthi M., Saez, Natalie J., Clayton, Daniel, Budusan, Elena, Watson, Emma E., Tucker, Isaac J., Rash, Lachlan D., King, Glenn F. and Payne, Richard J. (2021). Total synthesis of the spider-venom peptide Hi1a. Organic Letters, 23 (21) acs.orglett.1c03112, 8375-8379. doi: 10.1021/acs.orglett.1c03112 |
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2021 Journal Article The concise guide to pharmacology 2021/22: ion channelsAlexander, Stephen PH, Mathie, Alistair, Peters, John A, Veale, Emma L, Striessnig, Jörg, Kelly, Eamonn, Armstrong, Jane F, Faccenda, Elena, Harding, Simon D, Pawson, Adam J, Southan, Christopher, Davies, Jamie A, Aldrich, Richard W., Attali, Bernard, Baggetta, Austin M, Becirovic, Elvir, Biel, Martin, Bill, Roslyn M., Catterall, William A., Conner, Alex C., Davies, Paul, Delling, Markus, Virgilio, Francesco Di, Falzoni, Simonetta, Fenske, Stefanie, George, Chandy, Goldstein, Steve A. N., Grissmer, Stephan, Ha, Kotdaji ... Zhu, Michael (2021). The concise guide to pharmacology 2021/22: ion channels. British Journal of Pharmacology, 178 (S1), S157-S245. doi: 10.1111/bph.15539 |
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2021 Journal Article Acid-Sensing Ion Channels: Expression and Function in Resident and Infiltrating Immune Cells in the Central Nervous SystemFoster, Victoria S., Rash, Lachlan D., King, Glenn F. and Rank, Michelle M. (2021). Acid-Sensing Ion Channels: Expression and Function in Resident and Infiltrating Immune Cells in the Central Nervous System. Frontiers in cellular neuroscience, 15 738043, 1-16. doi: 10.3389/fncel.2021.738043 |
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2021 Journal Article Acid-sensing (proton-gated) ion channels (ASICs) in GtoPdb v.2021.3Kellenberger, Stephan and Rash, Lachlan D. (2021). Acid-sensing (proton-gated) ion channels (ASICs) in GtoPdb v.2021.3. IUPHAR/BPS Guide to Pharmacology CITE, 2021 (3). doi: 10.2218/gtopdb/f118/2021.3 |
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2021 Journal Article Mambalgin-3 potentiates human acid-sensing ion channel 1b under mild to moderate acidosis: implications as an analgesic leadCristofori-Armstrong, Ben, Budusan, Elena and Rash, Lachlan D. (2021). Mambalgin-3 potentiates human acid-sensing ion channel 1b under mild to moderate acidosis: implications as an analgesic lead. Proceedings of the National Academy of Sciences, 118 (8) e2021581118, 1-3. doi: 10.1073/pnas.2021581118 |
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2021 Other Outputs Neuroprotective agents derived from spider venom peptidesKing, Glenn , Rash, Lachlan Douglas, Chassagnon, Irene, Pineda Gonzalez, Sandy Steffany, Widdop, Robert Edward and Ireland, Claudia Ann (2021). Neuroprotective agents derived from spider venom peptides. 10881712. |
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2020 Journal Article Acid-sensing (proton-gated) ion channels (ASICs) (version 2020.5) in the IUPHAR/BPS Guide to Pharmacology DatabaseKellenberger, Stephan and Rash, Lachlan D. (2020). Acid-sensing (proton-gated) ion channels (ASICs) (version 2020.5) in the IUPHAR/BPS Guide to Pharmacology Database. IUPHAR/BPS Guide to Pharmacology CITE, 2020 (5). doi: 10.2218/gtopdb/f118/2020.5 |
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2019 Journal Article The diversity of venom: the importance of behavior and venom system morphology in understanding its ecology and evolutionSchendel, Vanessa, Rash, Lachlan D., Jenner, Ronald A. and Undheim, Eivind A. B. (2019). The diversity of venom: the importance of behavior and venom system morphology in understanding its ecology and evolution. Toxins, 11 (11) 666, 666. doi: 10.3390/toxins11110666 |
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2019 Journal Article The Concise Guide to Pharmacology 2019/20: Ion channelsAlexander, Stephen P.H., Mathie, Alistair, Peters, John A., Veale, Emma L., Striessnig, Jörg, Kelly, Eamonn, Armstrong, Jane F., Faccenda, Elena, Harding, Simon D., Pawson, Adam J., Sharman, Joanna L., Southan, Christopher, Davies, Jamie A., Aldrich, Richard W., Becirovic, Elvir, Biel, Martin, Catterall, William A., Conner, Alex C., Davies, Paul, Delling, Markus, Virgilio, Francesco Di, Falzoni, Simonetta, George, Chandy, Goldstein, Steve A.N., Grissmer, Stephan, Ha, Kotdaji, Hammelmann, Verena, Hanukoglu, Israel, Jarvis, Mike ... Zhu, Michael (2019). The Concise Guide to Pharmacology 2019/20: Ion channels. British Journal of Pharmacology, 176 (S1), S142-S228. doi: 10.1111/bph.14749 |
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2019 Journal Article Acid-sensing (proton-gated) ion channels (ASICs) (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology DatabaseKellenberger, Stephan, Rash, Lachlan D. and Schild, Laurent (2019). Acid-sensing (proton-gated) ion channels (ASICs) (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database. IUPHAR/BPS Guide to Pharmacology CITE, 2019 (4). doi: 10.2218/gtopdb/f118/2019.4 |
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2019 Journal Article The modulation of acid-sensing ion channel 1 by PcTx1 is pH-, subtype- and species-dependent: importance of interactions at the channel subunit interface and potential for engineering selective analoguesCristofori-Armstrong, Ben, Saez, Natalie J., Chassagnon, Irène R., King, Glenn F. and Rash, Lachlan D. (2019). The modulation of acid-sensing ion channel 1 by PcTx1 is pH-, subtype- and species-dependent: importance of interactions at the channel subunit interface and potential for engineering selective analogues. Biochemical Pharmacology, 163, 381-390. doi: 10.1016/j.bcp.2019.03.004 |
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2019 Journal Article D. russelii venom mediates vasodilatation of resistance like arteries via activation of Kv and KCa ChannelsKakumanu, Rahini, Kuruppu, Sanjaya, Rash, Lachlan, Isbister, Geoffrey, Hodgson, Wayne and Kemp-Harper, Barbara (2019). D. russelii venom mediates vasodilatation of resistance like arteries via activation of Kv and KCa Channels. Toxins, 11 (4) 197, 197. doi: 10.3390/toxins11040197 |
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2019 Journal Article Novel conorfamides from Conus austini venom modulate both nicotinic acetylcholine receptors and acid-sensing ion channelsJin, Ai-hua, Cristofori-Armstrong, Ben, Rash, Lachlan D., Román González, Sergio Agustín, Espinosa, Roberto Arreguín, Lewis, Richard J., Alewood, Paul F. and Vetter, Irina (2019). Novel conorfamides from Conus austini venom modulate both nicotinic acetylcholine receptors and acid-sensing ion channels. Biochemical Pharmacology, 164, 342-348. doi: 10.1016/j.bcp.2019.04.025 |
