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2013 Journal Article ASIC3: first the heartache, now a migraine!Rash, Lachlan D. (2013). ASIC3: first the heartache, now a migraine!. Headache, 53 (8), 1204-1206. doi: 10.1111/head.12170 |
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2013 Journal Article Production of recombinant disulfide-rich venom peptides for structural and functional analysis via expression in the periplasm of E. coliKlint, Julie K., Senff, Sebastian, Saez, Natalie J., Seshadri, Radha, Lau, Ho Yee, Bende, Nira J., Undheim, Eivind A. B., Rash, Lachlan D., Mobli, Mehdi and King, Glenn F. (2013). Production of recombinant disulfide-rich venom peptides for structural and functional analysis via expression in the periplasm of E. coli. PLoS One, 8 (5) e63865, e63865.1-e63865.12. doi: 10.1371/journal.pone.0063865 |
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2012 Journal Article Functional expression in Escherichia coli of the disulfide-rich sea anemone peptide APETx2, a potent blocker of acid-sensing ion channel 3Anangi, Raveendra, Rash, Lachlan D., Mobli, Mehdi and King, Glenn F. (2012). Functional expression in Escherichia coli of the disulfide-rich sea anemone peptide APETx2, a potent blocker of acid-sensing ion channel 3. Marine Drugs, 10 (7), 1605-1618. doi: 10.3390/md10071605 |
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2012 Journal Article Cyclisation increases the stability of the sea anemone peptide APETx2 but decreases its activity at acid-sensing ion channel 3Jensen, Jonas E., Mobli, Mehdi, Brust, Andreas, Alewood, Paul F., King, Glenn F. and Rash, Lachlan D. (2012). Cyclisation increases the stability of the sea anemone peptide APETx2 but decreases its activity at acid-sensing ion channel 3. Marine Drugs, 10 (7), 1511-1527. doi: 10.3390/md10071511 |
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2012 Journal Article Inhibition of voltage-gated Na+ currents in sensory neurons by the sea anemone toxin APETx2Blanchard, Maxime G., Rash, Lachlan D. and Kellenberger, Stephan (2012). Inhibition of voltage-gated Na+ currents in sensory neurons by the sea anemone toxin APETx2. British Journal of Pharmacology, 165 (7), 2167-2177. doi: 10.1111/j.1476-5381.2011.01674.x |
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2012 Conference Publication Structure activity studies and therapeutic potential of venom peptides that target acid-sensing ion channelsRash, Lachlan D. (2012). Structure activity studies and therapeutic potential of venom peptides that target acid-sensing ion channels. Joint ASCEPT-APSA 2012 Conference, Sydney, Australia, 2-5 December 2012. |
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2012 Conference Publication Inhibition of voltage-gated Na+ currents in sensory neurons by the sea anemone toxin APETx2Blanchard, Maxime, Rash, Lachlan D. and Kellenberger, Stephan (2012). Inhibition of voltage-gated Na+ currents in sensory neurons by the sea anemone toxin APETx2. 41st Annual Meeting of the Society for Neuroscience (Neuroscience 2011), Washington, United States, 12-16 November 2011. St. Louis, MO, United States: Cell Press. doi: 10.1016/j.bpj.2011.11.1780 |
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2011 Journal Article A dynamic pharmacophore drives the interaction between psalmotoxin-1 and the putative drug target acid-sensing ion channel 1aSaez, Natalie J., Mobli, Mehdi, Bieri, Michael, Chassagnon, Irene R., Malde, Alpeshkumar K., Gamsjaeger, Roland, Mark, Alan E., Gooley, Paul R., Rash. Lachlan D. and King, Glenn F. (2011). A dynamic pharmacophore drives the interaction between psalmotoxin-1 and the putative drug target acid-sensing ion channel 1a. Molecular Pharmacology, 80 (5), 796-808. doi: 10.1124/mol.111.072207 |
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2011 Journal Article De novo sequencing of peptides from the parotid secretion of the cane toad, Bufo marinus (Rhinella marina)Rash, Lachlan D., Morales, Rodrigo A.V., Vink, Simone and Alewood, Paul F. (2011). De novo sequencing of peptides from the parotid secretion of the cane toad, Bufo marinus (Rhinella marina). Toxicon, 57 (2), 208-216. doi: 10.1016/j.toxicon.2010.11.012 |
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2011 Conference Publication Actions of ASIC1a and ASIC3 inhibitors in rat chronic pain modelsMozar, C. A., Sun, T., Rash, L. D., King, G. F. and Christie, M. J. (2011). Actions of ASIC1a and ASIC3 inhibitors in rat chronic pain models. 41st Annual Meeting of the Society for Neuroscience (Neuroscience 2011), Washington, United States, 12-16 November 2011. |
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2011 Journal Article Venomics: A new paradigm for natural products-based drug discoveryVetter, Irina, Davis, Jasmine L., Rash, Lachlan D., Anangi, Raveendra, Mobli, Mehdi, Alewood, Paul F., Lewis, Richard J. and King, Glenn F. (2011). Venomics: A new paradigm for natural products-based drug discovery. Amino Acids, 40 (1), 15-28. doi: 10.1007/s00726-010-0516-4 |
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2010 Journal Article Spider-venom peptides as therapeuticsSeaz, Natalie J., Senff, Sebastian, Jensen, Jonas E., Er, Sing Yan, Herzig, Volker, Rash, Lachlan D. and King, Glenn F. (2010). Spider-venom peptides as therapeutics. Toxins, 2 (12), 2851-2871. doi: 10.3390/toxins2122851 |
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2009 Journal Article Chemical synthesis and folding of APETx2, a potent and selective inhibitor of acid sensing ion channel 3Jensen, J. E., Durek, T, Alewood, P. F., Adams, D. J., King, G. F. and Rash, L. D. (2009). Chemical synthesis and folding of APETx2, a potent and selective inhibitor of acid sensing ion channel 3. TOXICON, 54 (1), 56-61. doi: 10.1016/j.toxicon.2009.03.014 |
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2006 Journal Article Neurotoxicity and Other Pharmacological Activities of the Snake Venom Phospholipase A2 OS2: The N-Terminal Region Is More Important Than Enzymatic ActivityRouault, Morgane, Rash, Lachlan D., Escoubas, Pierre, Boilard, Eric, Bollinger, James, Lomonte, Bruno, Maurin, Thomas, Guillaume, Carole, Canaan, Stéphane, Deregnaucourt, Christiane, Schrével, Joseph, Doglio, Alain, Gutiérrez, José María, Lazdunski, Michel, Gelb, Michael H. and Lambeau, Gérard (2006). Neurotoxicity and Other Pharmacological Activities of the Snake Venom Phospholipase A2 OS2: The N-Terminal Region Is More Important Than Enzymatic Activity. Biochemistry, 45 (18), 5800-5816. doi: 10.1021/bi060217r |
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2006 Journal Article Four Novel Tarantula Toxins as Selective Modulators of Voltage-Gated Sodium Channel SubtypesBosmans, Frank, Rash, Lachlan, Zhu, Shunyi, Diochot, Sylvie, Lazdunski, Michel, Escoubas, Pierre and Tytgat, Jan (2006). Four Novel Tarantula Toxins as Selective Modulators of Voltage-Gated Sodium Channel Subtypes. Molecular Pharmacology, 69 (2), 419-429. doi: 10.1124/mol.105.015941 |
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2006 Journal Article The receptor site of the spider toxin PcTx1 on the proton-gated cation channel ASIC1aSalinas, Miguel, Rash, Lachlan D., Baron, Anne, Lambeau, Gerard, Escoubas, Pierre and Lazdunski, Michel (2006). The receptor site of the spider toxin PcTx1 on the proton-gated cation channel ASIC1a. Journal of Physiology, 570 (2), 339-354. doi: 10.1113/jphysiol.2005.095810 |
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2004 Journal Article A new sea anemone peptide, APETx2, inhibits ASIC3, a major acid-sensitive channel in sensory neuronsDiochot, Sylvie, Baron, Anne, Rash, Lachlan D., Deval, Emmanuel, Escoubas, Pierre, Scarzello, Sabine, Salinas, Miguel and Lazdunsk, Michel (2004). A new sea anemone peptide, APETx2, inhibits ASIC3, a major acid-sensitive channel in sensory neurons. The EMBO journal, 23 (7), 1516-1525. doi: 10.1038/sj.emboj.7600177 |
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2004 Journal Article Tarantulas: eight-legged pharmacists and combinatorial chemistsEscoubas, Pierre and Rash, Lachlan (2004). Tarantulas: eight-legged pharmacists and combinatorial chemists. Toxicon, 43 (5), 555-574. doi: 10.1016/j.toxicon.2004.02.007 |
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2002 Journal Article Pharmacology and biochemistry of spider venomsRash, Lachlan D. and Hodgson, Wayne C. (2002). Pharmacology and biochemistry of spider venoms. Toxicon, 40 (3), 225-254. doi: 10.1016/S0041-0101(01)00199-4 |
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2002 Journal Article Synthesis of Some Nefopam Analogues as Potential AnalgesicsRosamilla, Anthony E., Mayes, Penelope A., Papadopoulos, Roslyn, Campi, Eva M., Jackson, W. Roy, Rash, Lachlan and Jarrott, Bevyn (2002). Synthesis of Some Nefopam Analogues as Potential Analgesics. Australian Journal of Chemistry, 55 (9), 577-585. doi: 10.1071/CH02097 |
