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2017 Journal Article Gaq proteins: molecular pharmacology and therapeutic potentialKamato, Danielle, Mitra, Partha, Davis, Felicity, Osman, Narin, Chaplin, Rebecca, Cabot, Peter J., Afroz, Rizwana, Thomas, Walter, Zheng, Wenhua, Kaur, Harveen, Brimble, Margaret and Little, Peter J. (2017). Gaq proteins: molecular pharmacology and therapeutic potential. Cellular and Molecular Life Sciences, 74 (8), 1379-1390. doi: 10.1007/s00018-016-2405-9 |
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2017 Journal Article Transactivation of the epidermal growth factor receptor in responses to myocardial stress and cardioprotectionReichelt, Melissa E., O'Brien, Shannon, Thomas, Walter G. and Headrick, John P. (2017). Transactivation of the epidermal growth factor receptor in responses to myocardial stress and cardioprotection. International Journal of Biochemistry and Cell Biology, 83, 97-110. doi: 10.1016/j.biocel.2016.12.014 |
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2017 Journal Article CRIM1 is necessary for coronary vascular endothelial cell development and homeostasisIyer, Swati, Chhabra, Yash, Harvey, Tracey J., Wang, Richard, Chiu, Han Sheng, Smith, A. G., Thomas, Walter G., Pennisi, David J. and Piper, Michael (2017). CRIM1 is necessary for coronary vascular endothelial cell development and homeostasis. Journal of Molecular Histology, 48 (1), 53-61. doi: 10.1007/s10735-016-9702-3 |
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2016 Journal Article Integrating the GPCR transactivation-dependent and biased signalling paradigms in the context of PAR1 signallingLittle, P. J., Hollenberg, M. D, Kamato, D., Thomas, W., Chen, J., Wang, T., Zheng, W. and Osman, N. (2016). Integrating the GPCR transactivation-dependent and biased signalling paradigms in the context of PAR1 signalling. British Journal of Pharmacology, 173 (20), 2992-3000. doi: 10.1111/bph.13398 |
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2016 Journal Article Crim1 has cell-autonomous and paracrine roles during embryonic heart developmentIyer, Swati, Chou, Fang Yu, Wang, Richard, Chiu, Han Sheng, Raju, Vinay K. Sundar, Little, Melissa H., Thomas, Walter G., Piper, Michael and Pennisi, David J. (2016). Crim1 has cell-autonomous and paracrine roles during embryonic heart development. Scientific Reports, 6 (1) 19832, 19832 .1-19832 .15. doi: 10.1038/srep19832 |
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2016 Journal Article Epidermal growth factor receptor transactivation: mechanisms, pathophysiology, and potential therapies in the cardiovascular systemForrester, Steven J., Kawai, Tatsuo, O'Brien, Shannon, Thomas, Walter, Harris, Raymond C. and Eguchi, Satoru (2016). Epidermal growth factor receptor transactivation: mechanisms, pathophysiology, and potential therapies in the cardiovascular system. Annual Review of Pharmacology and Toxicology, 56 (1), 627-653. doi: 10.1146/annurev-pharmtox-070115-095427 |
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2016 Journal Article Taste and hypertension in humans: targeting cardiovascular diseaseRoura, Eugeni, Foster, Simon, Winklebach, Anja, Navarro, Marta, Thomas, Walter, Campbell, Katrina and Stowasser, Michael (2016). Taste and hypertension in humans: targeting cardiovascular disease. Current Pharmaceutical Design, 22 (15), 2290-2305. doi: 10.2174/1381612822666160216151545 |
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2015 Journal Article Angiotensin receptors: Interpreters of pathophysiological angiotensinergic stimulisKarnik, Sadashiva S., Unal, Hamiyet, Kemp, Jacqueline R., Tirupula, Kalyan C., Eguchi, Satoru, Vanderheyden, Patrick M. L. and Thomas, Walter G. (2015). Angiotensin receptors: Interpreters of pathophysiological angiotensinergic stimulis. Pharmacological Reviews, 67 (4), 754-819. doi: 10.1124/pr.114.010454 |
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2015 Journal Article Variability in human bitter taste sensitivity to chemically diverse compounds can be accounted for by differential TAS2R activationRoura, Eugeni, Aldayyani, Asya, Thavaraj, Pridhuvi, Prakash, Sangeeta, Greenway, Delma, Thomas, Walter G., Meyerhof, Wolfgang, Roudnitzky, Natacha and Foster, Simon R. (2015). Variability in human bitter taste sensitivity to chemically diverse compounds can be accounted for by differential TAS2R activation. Chemical Senses, 40 (6), 427-435. doi: 10.1093/chemse/bjv024 |
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2015 Journal Article Helix 8 of the angiotensin- II type 1A receptor interacts with phosphatidylinositol phosphates and modulates membrane insertionHirst, Daniel J., Lee, Tzong-Hsien, Pattenden, Leonard K., Thomas, Walter G. and Aguilar, Marie-Isabel (2015). Helix 8 of the angiotensin- II type 1A receptor interacts with phosphatidylinositol phosphates and modulates membrane insertion. Scientific Reports, 5 (1) 9972, 1-14. doi: 10.1038/srep09972 |
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2015 Journal Article Cardiac gene expression data and in silico analysis provide novel insights into human and mouse taste receptor gene regulationFoster, Simon R., Porrello, Enzo R., Stefani, Maurizio, Smith, Nicola J., Molenaar, Peter, Dos Remedios, Cristobal G., Thomas, Walter G. and Ramialison, Mirana (2015). Cardiac gene expression data and in silico analysis provide novel insights into human and mouse taste receptor gene regulation. Naunyn-Schmiedeberg's Archives of Pharmacology, 388 (10) 1118, 1009-1027. doi: 10.1007/s00210-015-1118-1 |
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2015 Journal Article Structural determinants for binding to angiotensin converting enzyme 2 (ACE2) and angiotensin receptors 1 and 2Clayton, Daniel, Hanchapola, Iresha, Thomas, Walter G., Widdop, Robert E., Smith, Alexander I., Perlmutter, Patrick and Aguilar, Marie-Isabel (2015). Structural determinants for binding to angiotensin converting enzyme 2 (ACE2) and angiotensin receptors 1 and 2. Frontiers in Pharmacology, 6 (JAN) 05, 5.1-5.9. doi: 10.3389/fphar.2015.00005 |
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2015 Journal Article G protein-coupled receptors in cardiac biology: old and new receptorsFoster, Simon R, Roura, Eugeni, Molenaar, Peter and Thomas, Walter G. (2015). G protein-coupled receptors in cardiac biology: old and new receptors. Biophysical Reviews, 7 (1), 77-89. doi: 10.1007/s12551-014-0154-2 |
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2015 Journal Article Extracellular surface residues of theα1b-adrenoceptor critical for g protein -coupled receptor functionsRagnarsson, Lotten, Andersson, Åsa, Thomas, Walter G. and Lewis, Richard J. (2015). Extracellular surface residues of theα1b-adrenoceptor critical for g protein -coupled receptor functions. Molecular Pharmacology, 87 (1), 121-129. doi: 10.1124/mol.114.094557 |
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2014 Journal Article Bitter taste receptor agonists elicit G-protein-dependent negative inotropy in the murine heartFoster, Simon R., Blank, Kristina, See Hoe, Louise E., Behrens, Maik, Meyerhof, Wolfgang, Peart, Jason N. and Thomas, Walter G. (2014). Bitter taste receptor agonists elicit G-protein-dependent negative inotropy in the murine heart. FASEB Journal, 28 (10), 4497-4508. doi: 10.1096/fj.14-256305 |
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2014 Journal Article Extrasensory perception: odorant and taste receptors beyond the nose and mouthFoster, Simon R., Roura, Eugeni and Thomas, Walter G. (2014). Extrasensory perception: odorant and taste receptors beyond the nose and mouth. Pharmacology and Therapeutics, 142 (1), 41-61. doi: 10.1016/j.pharmthera.2013.11.004 |
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2013 Journal Article A functional siRNA screen identifies genes modulating angiotensin II-mediated EGFR transactivationGeorge, Amee J., Purdue, Brooke W., Gould, Cathryn M., Thomas, Daniel W., Handoko, Yanny, Qian, Hongwei, Quaife-Ryan, Gregory A., Morgan, Kylie A., Simpson, Kaylene J., Thomas, Walter G. and Hannan, Ross D. (2013). A functional siRNA screen identifies genes modulating angiotensin II-mediated EGFR transactivation. Journal of Cell Science, 126 (23), 5377-5390. doi: 10.1242/jcs.128280 |
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2013 Journal Article Expression, Regulation and Putative Nutrient-Sensing Function of Taste GPCRs in the HeartFoster, Simon R., Porrello, Enzo R., Purdue, Brooke, Chan, Hsiu-Wen, Voigt, Anja, Frenzel, Sabine, Hannan, Ross D., Moritz, Karen M., Simmons, David G., Molenaar, Peter, Roura, Eugeni, Boehm, Ulrich, Meyerhof, Wolfgang and Thomas, Walter G. (2013). Expression, Regulation and Putative Nutrient-Sensing Function of Taste GPCRs in the Heart. PLoS ONE, 8 (5) e64579, e64579-1-e64579-10. doi: 10.1371/journal.pone.0064579 |
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2013 Journal Article PAQR3 modulates insulin signaling by shunting phosphoinositide 3-kinase p110α to the Golgi apparatusWang, Xiao, Wang, Lingdi, Zhu, Lu, Pan, Yi, Xiao, Fei, Liu, Weizhong, Wang, Zhenzhen, Guo, Feifan, Liu, Yong, Thomas, Walter G. and Chen, Yan (2013). PAQR3 modulates insulin signaling by shunting phosphoinositide 3-kinase p110α to the Golgi apparatus. Diabetes, 62 (2), 444-456. doi: 10.2337/db12-0244 |
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2012 Journal Article Angiotensin 1A receptors transfected into caudal ventrolateral medulla inhibit baroreflex gain and stress responsesPalma-Rigo, Kesia, Bassi, Jaspreet K., Nguyen-Huu, Thu-Phuc, Jackson, Kristy L., Davern, Pamela J., Chen, Daian, Elghozi, Jean-Luc, Thomas, Walter G., Allen, Andrew M. and Head, Geoffrey A. (2012). Angiotensin 1A receptors transfected into caudal ventrolateral medulla inhibit baroreflex gain and stress responses. Cardiovascular Research, 96 (2), 330-339. doi: 10.1093/cvr/cvs252 |
