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2020 Journal Article A phase 1, single centre, open label, escalating dose study to assess the safety, tolerability and immunogenicity of a therapeutic human papillomavirus (HPV) DNA vaccine (AMV002) for HPV-associated head and neck cancer (HNC)Chandra, J., Woo, W. P., Finlayson, N., Liu, H. Y., McGrath, M., Ladwa, R., Brauer, M., Xu, Y., Hanson, S., Panizza, B., Frazer, I. H. and Porceddu, Sandro V. (2020). A phase 1, single centre, open label, escalating dose study to assess the safety, tolerability and immunogenicity of a therapeutic human papillomavirus (HPV) DNA vaccine (AMV002) for HPV-associated head and neck cancer (HNC). Cancer Immunology, Immunotherapy, 70 (3), 743-753. doi: 10.1007/s00262-020-02720-7 |
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2020 Journal Article Oral HPV16 DNA as a screening tool to detect early oropharyngeal squamous cell carcinomaTang, Kai D., Vasani, Sarju, Menezes, Lilian, Taheri, Touraj, Walsh, Laurence J., Hughes, Brett G.M., Frazer, Ian H., Kenny, Liz, Scheper, Gert C. and Punyadeera, Chamindie (2020). Oral HPV16 DNA as a screening tool to detect early oropharyngeal squamous cell carcinoma. Cancer Science, 111 (10) cas.14585, 3854-3861. doi: 10.1111/cas.14585 |
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2020 Journal Article Dysregulation of stemness pathways in HPV mediated cervical malignant transformation identifies potential oncotherapy targetsBudhwani, Megha, Lukowski, Samuel W., Porceddu, Sandro V., Frazer, Ian H. and Chandra, Janin (2020). Dysregulation of stemness pathways in HPV mediated cervical malignant transformation identifies potential oncotherapy targets. Frontiers in Cellular and Infection Microbiology, 10 307, 307. doi: 10.3389/fcimb.2020.00307 |
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2020 Journal Article Collaboration in the war against viruses: a multidisciplinary international effortFrazer, Ian H. (2020). Collaboration in the war against viruses: a multidisciplinary international effort. The Innovation, 1 (1) 100011, 100011. doi: 10.1016/j.xinn.2020.04.011 |
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2020 Journal Article The Innovation: A Journal to See the Unseen and Change the UnchangedChen, Ke, Huang, Tao, Liu, Enke, Lu, Yuyuan, Huo, Zhigang, Mi, Lei, Zhang, Wei and Frazer, Ian (2020). The Innovation: A Journal to See the Unseen and Change the Unchanged. Innovation(China), 1 (1) 100014, 1-2. doi: 10.1016/j.xinn.2020.04.014 |
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2020 Journal Article Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating AntibodiesChew, Hui Yi, De Lima, Priscila O., Gonzalez Cruz, Jazmina L., Banushi, Blerida, Echejoh, Godwins, Hu, Lingbo, Joseph, Shannon R., Lum, Benedict, Rae, James, O'Donnell, Jake S., Merida de Long, Lilia, Okano, Satomi, King, Brigid, Barry, Rachael, Moi, Davide, Mazzieri, Roberta, Thomas, Ranjeny, Souza-Fonseca-Guimaraes, Fernando, Foote, Matthew, McCluskey, Adam, Robinson, Phillip J., Frazer, Ian H., Saunders, Nicholas A., Parton, Robert G., Dolcetti, Riccardo, Cuff, Katharine, Martin, Jennifer H., Panizza, Benedict, Walpole, Euan ... Simpson, Fiona (2020). Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating Antibodies. Cell, 180 (5), 895-914.e27. doi: 10.1016/j.cell.2020.02.019 |
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2020 Journal Article Antibody-free multiplex measurement of 23 human cytokines in primary cell culture secretome using targeted mass spectrometryKrueger, Annika, Stoll, Thomas, Shah, Alok K., Sinha, Rohit, Frazer, Ian H. and Hill, Michelle M. (2020). Antibody-free multiplex measurement of 23 human cytokines in primary cell culture secretome using targeted mass spectrometry. Analytical Chemistry, 92 (5), 3742-3750. doi: 10.1021/acs.analchem.9b05028 |
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2020 Journal Article Oral HPV16 prevalence in oral potentially malignant disorders and oral cavity cancersTang, Kai Dun, Menezes, Lilian, Baeten, Kurt, Walsh, Laurence J., Whitfield, Bernard C. S., Batstone, Martin D., Kenny, Liz, Frazer, Ian H., Scheper, Gert C. and Punyadeera, Chamindie (2020). Oral HPV16 prevalence in oral potentially malignant disorders and oral cavity cancers. Biomolecules, 10 (2) 223, 223. doi: 10.3390/biom10020223 |
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2020 Journal Article Importance of human papillomavirus infection in squamous cell carcinomas of the tongue in Guangdong Province, ChinaHuang, Kunsong, Ni, Guoying, Ma, Bowei, Chen, Shu, Luan, Yi, Wang, Tianfang, Walton, Shelley, Frazer, Ian, Liu, Xiaosong and Pan, Xuan (2020). Importance of human papillomavirus infection in squamous cell carcinomas of the tongue in Guangdong Province, China. The Journal of International Medical Research, 48 (1), 1-13. doi: 10.1177/0300060519897187 |
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2019 Journal Article Immune responses to a HSV-2 polynucleotide immunotherapy COR-1 in HSV-2 positive subjects: a randomized double blinded phase I/IIa trialChandra, Janin, Woo, Wai-Ping, Dutton, Julie L., Xu, Yan, Li, Bo, Kinrade, Sally, Druce, Julian, Finlayson, Neil, Griffin, Paul, Laing, Kerry J., Koelle, David M. and Frazer, Ian H. (2019). Immune responses to a HSV-2 polynucleotide immunotherapy COR-1 in HSV-2 positive subjects: a randomized double blinded phase I/IIa trial. PLoS One, 14 (12) e0226320, 1-20. doi: 10.1371/journal.pone.0226320 |
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2019 Journal Article HPV16 E7-driven epithelial hyperplasia promotes impaired antigen presentation and regulatory T cell developmentBashaw, Abate Assefa, Teoh, Siok M., Tuong, Zewen K., Leggatt, Graham R., Frazer, Ian H. and Chandra, Janin (2019). HPV16 E7-driven epithelial hyperplasia promotes impaired antigen presentation and regulatory T cell development. Journal of Investigative Dermatology, 139 (12), 2467-2476.e3. doi: 10.1016/j.jid.2019.03.1162 |
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2019 Journal Article Cytokine/chemokine profiles in squamous cell carcinoma correlate with precancerous and cancerous disease stageTuong, Zewen, Lewandowski, Andrew, Bridge, Jennifer, Gonzalez-Cruz, Jazmina, Yamada, Miko, Lambie, Duncan, Lewandowski, Richard, Steptoe, Raymond, Leggatt, Graham, Simpson, Fiona, Frazer, Ian, Soyer, Peter and Wells, James W. (2019). Cytokine/chemokine profiles in squamous cell carcinoma correlate with precancerous and cancerous disease stage. Scientific Reports, 9 (1) 17754, 17754. doi: 10.1038/s41598-019-54435-0 |
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2019 Journal Article Immunotherapy for HPV associated cancerFrazer, Ian H. and Chandra, Janin (2019). Immunotherapy for HPV associated cancer. Papillomavirus Research, 8 100176, 100176. doi: 10.1016/j.pvr.2019.100176 |
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2019 Journal Article Acute exercise does not improve immune response to HPV vaccination series in adolescentsBohn-Goldbaum, E., Lee, Vivian Y., Skinner, S. Rachel, Frazer, I. H., Khan, Burhan A., Booy, Robert and Edwards, Kate M. (2019). Acute exercise does not improve immune response to HPV vaccination series in adolescents. Papillomavirus Research, 8 100178, 100178. doi: 10.1016/j.pvr.2019.100178 |
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2019 Journal Article Selective persistence of HPV cross-neutralising antibodies following reduced-dose HPV vaccine schedulesToh, Zheng Quan, Kosasih, Jennie, Russell, Fiona M., Reyburn, Rita, Fong, James, Tuivaga, Evelyn, Ratu, Felisita T., Nguyen, Cattram D., Matanitobua, Silivia, Do, Lien Anh Ha, Menheniott, Trevelyan, Frazer, Ian H., Garland, Suzanne M., Mulholland, Edward Kim and Licciardi, Paul V. (2019). Selective persistence of HPV cross-neutralising antibodies following reduced-dose HPV vaccine schedules. Vaccines, 7 (4) 200, 200. doi: 10.3390/vaccines7040200 |
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2019 Journal Article Single-cell RNA sequencing reveals cell type-specific HPV expression in hyperplastic skin lesionsDevitt, Katharina, Hanson, Sarah J., Tuong, Zewen K., McMeniman, Erin, Soyer, H. Peter, Frazer, Ian H. and Lukowski, Samuel W. (2019). Single-cell RNA sequencing reveals cell type-specific HPV expression in hyperplastic skin lesions. Virology, 537, 14-19. doi: 10.1016/j.virol.2019.08.007 |
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2019 Journal Article Microprojection arrays applied to skin generate mechanical stress, induce an inflammatory transcriptome and cell death, and improve vaccine-induced immune responsesNg, Hwee-Ing, Tuong, Zewen K., Fernando, Germain J. P., Depelsenaire, Alexandra C. I., Meliga, Stefano C., Frazer, Ian H. and Kendall, Mark A. F. (2019). Microprojection arrays applied to skin generate mechanical stress, induce an inflammatory transcriptome and cell death, and improve vaccine-induced immune responses. npj Vaccines, 4 (1) 41, 41. doi: 10.1038/s41541-019-0134-4 |
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2019 Journal Article Human papillomavirus infection among head and neck squamous cell carcinomas in southern ChinaNi, Guoying, Huang, Kunsong, Luan, Yi, Cao, Zaizai, Chen, Shu, Ma, Bowei, Yuan, Jianwei, Wu, Xiaolian, Chen, Guoqiang, Wang, Tianfang, Li, Hejie, Walton, Shelley, Liu, Fang, Chen, Bobei, Wang, Yuejian, Pan, Xuan, Liu, Xiaosong and Frazer, Ian H. (2019). Human papillomavirus infection among head and neck squamous cell carcinomas in southern China. PLoS ONE, 14 (9) e0221045, e0221045. doi: 10.1371/journal.pone.0221045 |
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2019 Journal Article Papillomavirus immune evasion strategies target the infected cell and the local immune systemZhou, Chenhao, Tuong, Zewen Kelvin and Frazer, Ian Hector (2019). Papillomavirus immune evasion strategies target the infected cell and the local immune system. Frontiers in Oncology, 9 682, 682. doi: 10.3389/fonc.2019.00682 |
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2019 Journal Article The HPV vaccine storyFrazer, Ian H. (2019). The HPV vaccine story. ACS Pharmacology and Translational Science, 2 (3) acsptsci.9b00032, 210-212. doi: 10.1021/acsptsci.9b00032 |
