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2017 Journal Article Murine HPV16 E7-expressing transgenic skin effectively emulates the cellular and molecular features of human high-grade squamous intraepithelial lesionsTuong, Z. K., Noske, K., Kuo, P., Bashaw, A. A., Teoh, S. M. and Frazer, I. H. (2017). Murine HPV16 E7-expressing transgenic skin effectively emulates the cellular and molecular features of human high-grade squamous intraepithelial lesions. Papillomavirus Research, 5, 6-20. doi: 10.1016/j.pvr.2017.10.001 |
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2017 Journal Article The overexpression of salivary cytokeratins as potential diagnostic biomarkers in head and neck squamous cell carcinomasTang, Kai Dun, Kenny, Liz, Perry, Chris, Frazer, Ian and Punyadeera, Chamindie (2017). The overexpression of salivary cytokeratins as potential diagnostic biomarkers in head and neck squamous cell carcinomas. Oncotarget, 8 (42), 72272-72280. doi: 10.18632/oncotarget.19731 |
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2017 Journal Article RNA-seq reveals more consistent reference genes for gene expression studies in human non-melanoma skin cancersHoang, Van L. T., Tom, Lisa N., Quek, Xiu-Cheng, Tan, Jean-Marie, Payne, Elizabeth J., Lin, Lynlee L., Sinnya, Sudipta, Raphael, Anthony P., Lambie, Duncan, Frazer, Ian H., Dinger, Marcel E., Soyer, H. Peter and Prow, Tarl W. (2017). RNA-seq reveals more consistent reference genes for gene expression studies in human non-melanoma skin cancers. Peerj, 2017 (8) 3631, e3631. doi: 10.7717/peerj.3631 |
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2017 Journal Article Defining the genetic susceptibility to cervical neoplasia-A genome-wide association studyLeo, Paul J., Madeleine, Margaret M., Wang, Sophia, Schwartz, Stephen M., Newell, Felicity, Pettersson-Kymmer, Ulrika, Hemminki, Kari, Hallmans, Goran, Tiews, Sven, Steinberg, Winfried, Rader, Janet S., Castro, Felipe, Safaeian, Mahboobeh, Franco, Eduardo L., Coutlee, Francois, Ohlsson, Claes, Cortes, Adrian, Marshall, Mhairi, Mukhopadhyay, Pamela, Cremin, Katie, Johnson, Lisa G., Garland, Suzanne, Tabrizi, Sepehr N., Wentzensen, Nicolas, Sitas, Freddy, Little, Julian, Cruickshank, Maggie, Frazer, Ian H., Hildesheim, Allan and Brown, Matthew A. (2017). Defining the genetic susceptibility to cervical neoplasia-A genome-wide association study. Plos Genetics, 13 (8) e1006866, e1006866. doi: 10.1371/journal.pgen.1006866 |
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2017 Journal Article CD4+CD8β+ double-positive T cells in skin-draining lymph nodes respond to inflammatory signals from the skinOvergaard, Nana H., Cruz, Jazmina L., Bridge, Jennifer A., Nel, Hendrik J., Frazer, Ian H., La Gruta, Nicole K., Blumenthal, Antje, Steptoe, Raymond J. and Wells, James W. (2017). CD4+CD8β+ double-positive T cells in skin-draining lymph nodes respond to inflammatory signals from the skin. Journal of Leukocyte Biology, 102 (3), 837-844. doi: 10.1189/jlb.1AB0217-065R |
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2017 Journal Article Interferon-gamma derived from cytotoxic lymphocytes directly enhances their motility and cytotoxicityBhat, Purnima, Leggatt, Graham, Waterhouse, Nigel and Frazer, Ian H. (2017). Interferon-gamma derived from cytotoxic lymphocytes directly enhances their motility and cytotoxicity. Cell Death and Disease, 8 (6) e2836, e2836.1-e2836.11. doi: 10.1038/cddis.2017.67 |
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2017 Journal Article HPV16-E7-specific activated CD8 T cells in E7 transgenic skin and skin graftsJazayeri, Seyed D., Kuo, Paula, Leggatt, Graham R. and Frazer, Ian (2017). HPV16-E7-specific activated CD8 T cells in E7 transgenic skin and skin grafts. Frontiers in Immunology, 8 (MAY) 524, 524. doi: 10.3389/fimmu.2017.00524 |
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2017 Journal Article Clinical development strategy for a candidate group A streptococcal vaccineSchödel, Florian, Moreland, Nicole J., Wittes, Janet T., Mulholland, Kim, Frazer, Ian, Steer, Andrew C., Fraser, John D. and Carapetis, Jonathan (2017). Clinical development strategy for a candidate group A streptococcal vaccine. Vaccine, 35 (16), 2007-2014. doi: 10.1016/j.vaccine.2017.02.060 |
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2017 Journal Article Sustained antibody responses 6 years following 1, 2, or 3 doses of quadrivalent Human Papillomavirus (HPV) vaccine in adolescent Fijian girls, and subsequent responses to a single dose of bivalent HPV vaccine: a prospective cohort studyToh, Zheng Quan, Russell, Fiona M., Reyburn, Rita, Fong, James, Tuivaga, Evelyn, Ratu, Tupou, Nguyen, Cattram D., Devi, Rachel, Kama, Mike, Matanitobua, Silivia, Tabrizi, Sepehr N., Garland, Suzanne M., Sinha, Rohit, Frazer, Ian, Tikoduadua, Lisi, Kado, Joseph, Rafai, Eric, Mulholland, Edward K. and Licciardi, Paul V. (2017). Sustained antibody responses 6 years following 1, 2, or 3 doses of quadrivalent Human Papillomavirus (HPV) vaccine in adolescent Fijian girls, and subsequent responses to a single dose of bivalent HPV vaccine: a prospective cohort study. Clinical Infectious Diseases, 64 (7), 852-859. doi: 10.1093/cid/ciw865 |
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2017 Journal Article A pilot study into the association between oral health status and human papillomavirus-16 infectionSun, Charles Xiaohang, Bennett, Nigel, Tran, Peter, Tang, Kai Dun, Lim, Yenkai, Frazer, Ian, Samaranayake, Lakshman and Punyadeera, Chamindie (2017). A pilot study into the association between oral health status and human papillomavirus-16 infection. Diagnostics, 7 (1) 11, 11. doi: 10.3390/diagnostics7010011 |
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2017 Journal Article DNA vaccine encoding HPV16 oncogenes E6 and E7 induces potent cell-mediated and humoral immunity which protects in tumor challenge and drives E7-expressing skin graft rejectionChandra, Janin, Dutton, Julie L., Li, Bo, Woo, Wai-Ping, Xu, Yan, Tolley, Lynn K., Yong, Michelle, Wells, James W., Leggatt, Graham R., Finlayson, Neil and Frazer, Ian H. (2017). DNA vaccine encoding HPV16 oncogenes E6 and E7 induces potent cell-mediated and humoral immunity which protects in tumor challenge and drives E7-expressing skin graft rejection. Journal of Immunotherapy, 40 (2), 62-70. doi: 10.1097/CJI.0000000000000156 |
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2016 Journal Article Batf3 selectively determines acquisition of CD8+ dendritic cell phenotype and functionChandra, Janin, Kuo, Paula T. Y., Hahn, Anne M., Belz, Gabrielle T. and Frazer, Ian H. (2016). Batf3 selectively determines acquisition of CD8+ dendritic cell phenotype and function. Immunology and Cell Biology, 95 (2), 215-223. doi: 10.1038/icb.2016.83 |
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2016 Journal Article An escalating dose study to assess the safety, tolerability and immunogenicity of a Herpes Simplex Virus DNA vaccine, COR-1Dutton, Julie L., Woo, Wai-Ping, Chandra, Janin, Xu, Yan, Li, Bo, Finlayson, Neil, Griffin, Paul and Frazer, Ian H. (2016). An escalating dose study to assess the safety, tolerability and immunogenicity of a Herpes Simplex Virus DNA vaccine, COR-1. Human Vaccines and Immunotherapeutics, 12 (12), 3079-3088. doi: 10.1080/21645515.2016.1221872 |
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2016 Journal Article A mouse model of hyperproliferative human epithelium validated by keratin profiling ahows an aberrant cytoskeletal response to injuryZhussupbekova, Samal, Sinha, Rohit, Kuo, Paula, Lambert, Paul F., Frazer, Ian H. and Tuong, Zewen K. (2016). A mouse model of hyperproliferative human epithelium validated by keratin profiling ahows an aberrant cytoskeletal response to injury. Ebiomedicine, 9, 314-323. doi: 10.1016/j.ebiom.2016.06.011 |
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2016 Journal Article Role of ultraviolet radiation in papillomavirus-induced diseaseUberoi, Aayushi, Yoshida, Satoshi, Frazer, Ian H., Pitot, Henry C. and Lambert, Paul F. (2016). Role of ultraviolet radiation in papillomavirus-induced disease. PLoS Pathogens, 12 (5) e1005664, e1005664. doi: 10.1371/journal.ppat.1005664 |
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2016 Journal Article Epithelium expressing the E7 oncoprotein of HPV16 attracts immune-modulatory dendritic cells to the skin and suppresses their antigen-processing capacityChandra, Janin, Miao, Yan, Romoff, Natasha and Frazer, Ian H. (2016). Epithelium expressing the E7 oncoprotein of HPV16 attracts immune-modulatory dendritic cells to the skin and suppresses their antigen-processing capacity. Plos One, 11 (3) e0152886, e0152886. doi: 10.1371/journal.pone.0152886 |
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2016 Journal Article A pilot study to compare the detection of HPV-16 biomarkers in salivary oral rinses with tumour p16(INK4a) expression in head and neck squamous cell carcinoma patientsChai, Ryan C., Lim, Yenkai, Frazer, Ian H., Wan, Yunxia, Perry, Christopher, Jones, Lee, Lambie, Duncan and Punyadeera, Chamindie (2016). A pilot study to compare the detection of HPV-16 biomarkers in salivary oral rinses with tumour p16(INK4a) expression in head and neck squamous cell carcinoma patients. Bmc Cancer, 16 (1) 178, 178. doi: 10.1186/s12885-016-2217-1 |
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2015 Journal Article Interleukin-17A promotes arginase-1 production and 2,4-dinitrochlorobenzene-induced acute hyperinflammation in human papillomavirus E7 oncoprotein-expressing skinTran, Le Son, Mittal, Deepak, Mattarollo, Stephen R. and Frazer, Ian H. (2015). Interleukin-17A promotes arginase-1 production and 2,4-dinitrochlorobenzene-induced acute hyperinflammation in human papillomavirus E7 oncoprotein-expressing skin. Journal of Innate Immunity, 7 (4), 392-404. doi: 10.1159/000374115 |
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2015 Journal Article Langerhans cell homeostasis and activation is altered in hyperplastic human papillomavirus type 16 E7 expressing epidermisAbd Warif, Nor Malia, Stoitzner, Patrizia, Leggatt, Graham R., Mattarollo, Stephen R., Frazer, Ian H. and Hibma, Merilyn H. (2015). Langerhans cell homeostasis and activation is altered in hyperplastic human papillomavirus type 16 E7 expressing epidermis. PLoS One, 10 (5) e0127155, e0127155-e0127155. doi: 10.1371/journal.pone.0127155 |
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2015 Journal Article Does the nature of residual immune function explain the differential risk of non-melanoma skin cancer development in immunosuppressed organ transplant recipients?Jung, Ji-Won, Overgaard, Nana H., Burke, Michael T., Isbel, Nicole, Frazer, Ian H., Simpson, Fiona and Wells, James W. (2015). Does the nature of residual immune function explain the differential risk of non-melanoma skin cancer development in immunosuppressed organ transplant recipients?. International Journal of Cancer, 138 (2), 281-292. doi: 10.1002/ijc.29450 |
