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2014 Journal Article Mollemycin A: an antimalarial and antibacterial glyco-hexadepsipeptide-polyketide from an Australian marine-derived Streptomyces sp. (CMB-M0244)Raju, Ritesh, Khalil, Zeinab G., Piggott, Andrew M., Blumenthal, Antje, Gardiner, Donald L., Skinner-Adams, Tina S. and Capon, Robert J. (2014). Mollemycin A: an antimalarial and antibacterial glyco-hexadepsipeptide-polyketide from an Australian marine-derived Streptomyces sp. (CMB-M0244). Organic Letters, 16 (6), 1716-1719. doi: 10.1021/ol5003913 |
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2014 Journal Article A promoter-level mammalian expression atlasForest, Alistair R. R., Kawaji, Hideya, Rehli, Michael, Baillie, J. Kenneth, De Hoon, Michael J. L., Haberle, Vanja, Lassmann, Timo, Kulakovskiy, Ivan V., Lizio, Marina, Itoh, Masayoshi, Andersson, Robin, Mungall, Christopher J., Meehan, Terrence F., Schmeier, Sebastian, Bertin, Nicholas, Jorgensen, Mette, Dimont, Emmanuel, Arner, Erik, Schmidl, Christian, Schaefer, Ulf, Medvedeva, Yulia A., Plessy, Charles, Vitezic, Morana, Severin, Jessica, Semple, Colin A., Ishizu, Yuri, Young, Robert S., Francescatto, Margherita, Altschuler, Intikhab ... Hayashizaki, Yoshihide (2014). A promoter-level mammalian expression atlas. Nature, 507 (7493), 462-470. doi: 10.1038/nature13182 |
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2014 Journal Article Recombinant Wnt3a and Wnt5a elicit macrophage cytokine production and tolerization to microbial stimulation via Toll-like receptor 4Yu, C.-H., Nguyen, T.T.K., Irvine, K.M., Sweet, M.J., Frazer, I.H. and Blumenthal, A. (2014). Recombinant Wnt3a and Wnt5a elicit macrophage cytokine production and tolerization to microbial stimulation via Toll-like receptor 4. European Journal of Immunology, 44 (5), 1480-1490. doi: 10.1002/eji.201343959 |
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2013 Journal Article Indoleamine 2,3-dioxygenase activity contributes to local immune suppression in the skin expressing human papillomavirus oncoprotein E7Mittal, Deepak, Kassianos, Andrew. J, Tran, Lee S., Bergot, Anne-Sophie, Gosmann, Christina, Hofmann, Janin, Blumenthal, Antje, Leggatt, Graham R. and Frazer, Ian H. (2013). Indoleamine 2,3-dioxygenase activity contributes to local immune suppression in the skin expressing human papillomavirus oncoprotein E7. Journal of Investigative Dermatology, 133 (12), 2686-2694. doi: 10.1038/jid.2013.222 |
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2013 Journal Article Efficient biodistribution and gene silencing in the lung epithelium via intravenous liposomal delivery of siRNAMcCaskill, Jana, Singhania, Richa, Burgess, Melinda, Allavena, Rachel, Wu, Sherry, Blumenthal, Antje and McMillan, Nigel A. J. (2013). Efficient biodistribution and gene silencing in the lung epithelium via intravenous liposomal delivery of siRNA. Molecular Therapy - Nucleic Acid, 2 (1) e96, e96. doi: 10.1038/mtna.2013.22 |
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2012 Journal Article Generation of a genome scale lentiviral vector library for EF1α promoter-driven expression of hman ORFs and identification of human genes affecting viral titerSkalamera, Dubravka, Dahmer, Mareike, Purdon, Amy S., Wilson, Benjamin M., Ranall, Max V., Blumenthal, Antje, Gabrielli, Brian and Gonda, Thomas J. (2012). Generation of a genome scale lentiviral vector library for EF1α promoter-driven expression of hman ORFs and identification of human genes affecting viral titer. PloS One, 7 (12) e51733, e51733.1-e51733.15. doi: 10.1371/journal.pone.0051733 |
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2012 Journal Article M. tuberculosis induces potent activation of IDO-1, but this is not essential for the immunological control of infectionBlumenthal, Antje, Nagalingam, Gayathri, Huch, Jennifer H., Walker, Lara, Guillemin, Gilles J., Smythe, George A., Ehrt, Sabine, Britton, Warwick J. and Saunders, Bernadette M. (2012). M. tuberculosis induces potent activation of IDO-1, but this is not essential for the immunological control of infection. PloS One, 7 (5) e37314, e37314.1-e37314.11. doi: 10.1371/journal.pone.0037314 |
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2011 Journal Article Evaluating the sensitivity of Mycobacterium tuberculosis to biotin deprivation using regulated gene expressionPark, Sae Woong, Klotzsche, Marcus, Wilson, Daniel J., Boshoff, Helena I., Eoh, Hyungjin, Manjunatha, Ujjini, Blumenthal, Antje, Rhee, Kyu, Barry III, Clifton E., Aldrich, Courtney C., Ehrt, Sabine and Schnappinger, Dirk (2011). Evaluating the sensitivity of Mycobacterium tuberculosis to biotin deprivation using regulated gene expression. PLoS Pathogens, 7 (9) e1002264, e1002264.1-e1002264.10. doi: 10.1371/journal.ppat.1002264 |
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2010 Journal Article Simultaneous analysis of multiple mycobacterium tuberculosis knockdown mutants in vitro and in vivoBlumenthal, Antje, Trujillo, Carolina, Ehrt, Sabine and Schnappinger, Dirk (2010). Simultaneous analysis of multiple mycobacterium tuberculosis knockdown mutants in vitro and in vivo. PLoS One, 5 (12) e15667, e15667-1-e15667-12. doi: 10.1371/journal.pone.0015667 |
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2010 Journal Article Induction of ER stress in macrophages of tuberculosis granulomasSeimon, Tracie A., Kim, Mi-Jeong, Blumenthal, Antje, Koo, Jovanka, Ehrt, Sabine, Wainwright, Helen, Bekker, Linda-Gail, Kaplan, Gilla, Nathan, Carl, Tabas, Ira and Russell, David G. (2010). Induction of ER stress in macrophages of tuberculosis granulomas. PLoS One, 5 (9) e12772, e12772.1-e12772.12. doi: 10.1371/journal.pone.0012772 |
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2009 Journal Article Tuberculosis and host metabolism: ancient associations, fresh insightsBlumenthal, Antje, Isovski, Flonza and Rhee, Kyu Y. (2009). Tuberculosis and host metabolism: ancient associations, fresh insights. Translational Research, 154 (1), 7-14. doi: 10.1016/j.trsl.2009.04.004 |
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2009 Journal Article RP105 Facilitates Macrophage Activation by Mycobacterium tuberculosis LipoproteinsBlumenthal, A., Kobayashi, Toshihiko, Pierini, Lynda M., Banaei, Niaz, Ernst, Joel D., Miyake, Kensuke and Ehrt, Sabine (2009). RP105 Facilitates Macrophage Activation by Mycobacterium tuberculosis Lipoproteins. Cell Host and Microbe, 5 (1), 35-46. doi: 10.1016/j.chom.2008.12.002 |
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2006 Journal Article The wingless homolog WNT5A and its receptor Frizzled-5 regulate inflammatory responses of human mononuclear cells induced by microbial stimulationBlumenthal, Antje, Ehlers, Stefan, Lauber, Jörg, Buer, Jan, Lange, Christoph, Goldmann, Torsten, Heine, Holger, Brandt, Ernst and Reiling, Norbert (2006). The wingless homolog WNT5A and its receptor Frizzled-5 regulate inflammatory responses of human mononuclear cells induced by microbial stimulation. Blood, 108 (3), 965-973. doi: 10.1182/blood-2005-12-5046 |
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2005 Journal Article Expression of many immunologically important genes in Mycobacterium tuberculosis-infected macrophages is independent of both TLR2 and TLR4 but dependent on IFN-alpha beta receptor and STAT1Shi, Shuangping, Blumenthal, Antje, Hickey, Christopher M., Gandotra, Sheetal, Levy, David and Ehrt, Sabine (2005). Expression of many immunologically important genes in Mycobacterium tuberculosis-infected macrophages is independent of both TLR2 and TLR4 but dependent on IFN-alpha beta receptor and STAT1. Journal of Immunology, 175 (5), 3318-3328. doi: 10.4049/jimmunol.175.5.3318 |
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2005 Journal Article Common and unique gene expression signatures of human macrophages in response to four strains of Mycobacterium avium that differ in their growth and persistence characteristicsBlumenthal, Antje, Lauber, Jorg, Hoffmann, Reinhard, Ernst, Martin, Keller, Christine, Buer, Jan, Ehlers, Stefan and Reiling, Norbert (2005). Common and unique gene expression signatures of human macrophages in response to four strains of Mycobacterium avium that differ in their growth and persistence characteristics. Infection and Immunity, 73 (6), 3330-3341. doi: 10.1128/IAI.73.6.3330-3341.2005 |
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2004 Journal Article Detection of the 4977 bp deletion of mitochondrial DNA in different human blood cellsMohamed, S. A., Wesch, D., Blumenthal, A., Bruse, P., Windler, K., Ernst, M., Kabelitz, D., Oehmichen, M. and Meissner, C. (2004). Detection of the 4977 bp deletion of mitochondrial DNA in different human blood cells. Experimental Gerontology, 39 (2), 181-188. doi: 10.1016/j.exger.2003.10.011 |
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2004 Journal Article Resistance and susceptibility to tuberculosis analysed at the transcriptome level: Lessons from mouse macrophagesKeller, Christopher, Lauber, Joerg, Blumenthal, Antje, Buer, Jan and Ehlers, Stefan (2004). Resistance and susceptibility to tuberculosis analysed at the transcriptome level: Lessons from mouse macrophages. Tuberculosis, 84 (3-4), 144-158. doi: 10.1016/j.tube.2003.12.003 |
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2003 Journal Article Construction of a deep-rough mutant of Burkholderia cepacia ATCC 25416 and characterization of its chemical and biological propertiesGronow, Sabine, Noah, Christian, Blumenthal, Antje, Lindner, Buko and Brade, Helmut (2003). Construction of a deep-rough mutant of Burkholderia cepacia ATCC 25416 and characterization of its chemical and biological properties. Journal of Biological Chemistry, 278 (3), 1647-1655. doi: 10.1074/jbc.M206942200 |
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2002 Journal Article Control of mycobacterial replication in human macrophages: Roles of extracellular signal-regulated kinases 1 and 2 and p38 mitogen-activated protein kinase pathwaysBlumenthal, Antje, Ehlers, Stefan, Ernst, Martin, Flad, Hans-Dieter and Reiling, Norbert (2002). Control of mycobacterial replication in human macrophages: Roles of extracellular signal-regulated kinases 1 and 2 and p38 mitogen-activated protein kinase pathways. Infection and Immunity, 70 (9), 4961-4967. doi: 10.1128/IAI.70.9.4961-4967.2002 |
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2001 Journal Article Mycobacteria-induced TNF-alpha and IL-10 formation by human macrophages is differentially regulated at the level of mitogen-activated protein kinase activityReiling, N., Blumenthal, A., Flad, H. D., Ernst, M. and Ehlers, S. (2001). Mycobacteria-induced TNF-alpha and IL-10 formation by human macrophages is differentially regulated at the level of mitogen-activated protein kinase activity. Journal of Immunology, 167 (6), 3339-3345. doi: 10.4049/jimmunol.167.6.3339 |
