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2021

Journal Article

Dysfunction of the circadian clock in the kidney tubule leads to enhanced kidney gluconeogenesis and exacerbated hyperglycemia in diabetes

Ansermet, Camille, Centeno, Gabriel, Bignon, Yohan, Ortiz, Daniel, Pradervand, Sylvain, Garcia, Andy, Menin, Laure, Gachon, Frédéric, Yoshihara, Hikari AI. and Firsov, Dmitri (2021). Dysfunction of the circadian clock in the kidney tubule leads to enhanced kidney gluconeogenesis and exacerbated hyperglycemia in diabetes. Kidney International, 101 (3), 563-573. doi: 10.1016/j.kint.2021.11.016

Dysfunction of the circadian clock in the kidney tubule leads to enhanced kidney gluconeogenesis and exacerbated hyperglycemia in diabetes

2021

Journal Article

The Insulin/Insulin‐like Growth Factor signaling connects metabolism with sexual differentiation

Weger, Benjamin D. and Gachon, Frédéric (2021). The Insulin/Insulin‐like Growth Factor signaling connects metabolism with sexual differentiation. Acta Physiologica, 231 (3) e13576, e13576. doi: 10.1111/apha.13576

The Insulin/Insulin‐like Growth Factor signaling connects metabolism with sexual differentiation

2021

Journal Article

Systematic analysis of differential rhythmic liver gene expression mediated by the circadian clock and feeding rhythms

Weger, Benjamin D., Gobet, Cédric, David, Fabrice P. A., Atger, Florian, Martin, Eva, Phillips, Nicholas E., Charpagne, Aline, Weger, Meltem, Naef, Felix and Gachon, Frédéric (2021). Systematic analysis of differential rhythmic liver gene expression mediated by the circadian clock and feeding rhythms. Proceedings of the National Academy of Sciences, 118 (3) e2015803118, 1-12. doi: 10.1073/pnas.2015803118

Systematic analysis of differential rhythmic liver gene expression mediated by the circadian clock and feeding rhythms

2020

Journal Article

Neuronal activity regulates blood-brain barrier efflux transport through endothelial circadian genes

Pulido, Robert S., Munji, Roeben N., Chan, Tamara C., Quirk, Clare R., Weiner, Geoffrey A., Weger, Benjamin D., Rossi, Meghan J., Elmsaouri, Sara, Malfavon, Mario, Deng, Aaron, Profaci, Caterina P., Blanchette, Marie, Qian, Tongcheng, Foreman, Koji L., Shusta, Eric V., Gorman, Michael R., Gachon, Frédéric, Leutgeb, Stefan and Daneman, Richard (2020). Neuronal activity regulates blood-brain barrier efflux transport through endothelial circadian genes. Neuron, 108 (5), 937-952.e7. doi: 10.1016/j.neuron.2020.09.002

Neuronal activity regulates blood-brain barrier efflux transport through endothelial circadian genes

2020

Journal Article

Time to listen: circadian impact on auditory research

Cederroth, Christopher, Gachon, Frédéric and Canlon, Barbara (2020). Time to listen: circadian impact on auditory research. Current Opinion in Physiology, 18, 95-99. doi: 10.1016/j.cophys.2020.09.005

Time to listen: circadian impact on auditory research

2020

Journal Article

MondoA regulates gene expression in cholesterol biosynthesis-associated pathways required for zebrafish epiboly

Weger, Meltem, Weger, Benjamin D, Schink, Andrea, Takamiya, Masanari, Stegmaier, Johannes, Gobet, Cédric, Parisi, Alice, Kobitski, Andrei Yu, Mertes, Jonas, Krone, Nils, Strähle, Uwe, Nienhaus, Gerd Ulrich, Mikut, Ralf, Gachon, Frédéric, Gut, Philipp and Dickmeis, Thomas (2020). MondoA regulates gene expression in cholesterol biosynthesis-associated pathways required for zebrafish epiboly. eLife, 9 e57068, 1-35. doi: 10.7554/elife.57068

MondoA regulates gene expression in cholesterol biosynthesis-associated pathways required for zebrafish epiboly

2020

Journal Article

Proteomics in circadian biology

Mauvoisin, Daniel and Gachon, Frédéric (2020). Proteomics in circadian biology. Journal of Molecular Biology, 432 (12), 3565-3577. doi: 10.1016/j.jmb.2019.12.004

Proteomics in circadian biology

2020

Journal Article

Robust landscapes of ribosome dwell times and aminoacyl-tRNAs in response to nutrient stress in liver

Gobet, Cédric, Weger, Benjamin Dieter, Marquis, Julien, Martin, Eva, Neelagandan, Nagammal, Gachon, Frédéric and Naef, Felix (2020). Robust landscapes of ribosome dwell times and aminoacyl-tRNAs in response to nutrient stress in liver. Proceedings of the National Academy of Sciences, 117 (17), 9630-9641. doi: 10.1073/pnas.1918145117

Robust landscapes of ribosome dwell times and aminoacyl-tRNAs in response to nutrient stress in liver

2019

Journal Article

At the intersection of microbiota and circadian clock: are sexual dimorphism and growth hormones the missing link to pathology? Circadian clock and microbiota: potential egffect on growth hormone and sexual development

Weger, Benjamin D., Rawashdeh, Oliver and Gachon, Frédéric (2019). At the intersection of microbiota and circadian clock: are sexual dimorphism and growth hormones the missing link to pathology? Circadian clock and microbiota: potential egffect on growth hormone and sexual development. BioEssays, 41 (9) 1900059, e1900059. doi: 10.1002/bies.201900059

At the intersection of microbiota and circadian clock: are sexual dimorphism and growth hormones the missing link to pathology? Circadian clock and microbiota: potential egffect on growth hormone and sexual development

2019

Journal Article

Medicine in the Fourth Dimension

Cederroth, Christopher R., Albrecht, Urs, Bass, Joseph, Brown, Steven A., Dyhrfjeld-Johnsen, J., Gachon, Frederic, Green, Carla B., Hastings, Michael H., Helfrich-Förster, Charlotte, Hogenesch, John B., Lévi, Francis, Loudon, Andrew, Lundkvist, Gabriella B., Meijer, Johanna H., Rosbash, Michael, Takahashi, Joseph S., Young, Michael and Canlon, Barbara (2019). Medicine in the Fourth Dimension. Cell Metabolism, 30 (2), 238-250. doi: 10.1016/j.cmet.2019.06.019

Medicine in the Fourth Dimension

2019

Journal Article

Circadian regulation of cochlear sensitivity to noise by circulating glucocorticoids

Cederroth, Christopher R., Park, Jung-sub, Basinou, Vasiliki, Weger, Benjamin D., Tserga, Evangelia, Sarlus, Heela, Magnusson, Anna K., Kadri, Nadir, Gachon, Frédéric and Canlon, Barbara (2019). Circadian regulation of cochlear sensitivity to noise by circulating glucocorticoids. Current Biology, 29 (15), 2477-2487.e6. doi: 10.1016/j.cub.2019.06.057

Circadian regulation of cochlear sensitivity to noise by circulating glucocorticoids

2019

Journal Article

Microbiota and the clock: sexual dimorphism matters!

Weger, Benjamin D and Gachon, Frédéric (2019). Microbiota and the clock: sexual dimorphism matters!. Aging, 11 (12), 3893-3894. doi: 10.18632/aging.102051

Microbiota and the clock: sexual dimorphism matters!

2019

Journal Article

Protéomique circadienne

Gachon, Frédéric (2019). Protéomique circadienne. Biologie aujourd'hui, 212 (3-4), 55-59. doi: 10.1051/jbio/2018025

Protéomique circadienne

2019

Journal Article

The mouse microbiome is required for sex-specific diurnal rhythms of gene expression and metabolism

Weger, Benjamin D, Gobet, Cédric, Yeung, Jake, Martin, Eva, Jimenez, Sonia, Betrisey, Bertrand, Foata, Francis, Berger, Bernard, Balvay, Aurélie, Foussier, Anne, Charpagne, Aline, Boizet-Bonhoure, Brigitte, Chou, Chieh Jason, Naef, Felix and Gachon, Frédéric (2019). The mouse microbiome is required for sex-specific diurnal rhythms of gene expression and metabolism. Cell Metabolism, 29 (2), 362-382. doi: 10.1016/j.cmet.2018.09.023

The mouse microbiome is required for sex-specific diurnal rhythms of gene expression and metabolism

2018

Journal Article

Chronotype: implications for epidemiologic studies on chrono-nutrition and cardiometabolic health

Almoosawi, Suzana, Vingeliene, Snieguole, Gachon, Frederic, Voortman, Trudy, Palla, Luigi, Johnston, Jonathan D, Van Dam, Rob Martinus, Darimont, Christian and Karagounis, Leonidas G (2018). Chronotype: implications for epidemiologic studies on chrono-nutrition and cardiometabolic health. Advances in Nutrition , 10 (1), 30-42. doi: 10.1093/advances/nmy070

Chronotype: implications for epidemiologic studies on chrono-nutrition and cardiometabolic health

2018

Journal Article

Cross-regulatory circuits linking inflammation, high-fat diet, and the circadian clock

Gachon, Frederic, Yeung, Jake and Naef, Felix (2018). Cross-regulatory circuits linking inflammation, high-fat diet, and the circadian clock. Genes & Development, 32 (21-22), 1359-1360. doi: 10.1101/gad.320911.118

Cross-regulatory circuits linking inflammation, high-fat diet, and the circadian clock

2018

Journal Article

Transcriptomic analyses reveal rhythmic and CLOCK-driven pathways in human skeletal muscle

Perrin, Laurent, Loizides-Mangold, Ursula, Chanon, Stephanie, Gobet, Cedric, Hulo, Nicolas, Isenegger, Laura, Weger, Benjamin D., Migliavacca, Eugenia, Charpagne, Aline, Betts, James A., Walhin, Jean-Philippe, Templeman, Lain, Stokes, Keith, Thompson, Dylan, Tsintzas, Kostas, Robert, Maud, Howald, Cedric, Riezman, Howard, Feige, Jerome N., Karagounis, Leonidas G., Johnston, Jonathan D., Dermitzakis, Emmanouil T., Gachon, Frederic, Lefai, Etienne and Dibner, Charna (2018). Transcriptomic analyses reveal rhythmic and CLOCK-driven pathways in human skeletal muscle. eLife, 7 e34114. doi: 10.7554/eLife.34114

Transcriptomic analyses reveal rhythmic and CLOCK-driven pathways in human skeletal muscle

2018

Journal Article

Clock-dependent chromatin topology modulates circadian transcription and behavior

Mermet, Jérôme, Yeung, Jake, Hurni, Clémence, Mauvoisin, Daniel, Gustafson, Kyle, Jouffe, Céline, Nicolas, Damien, Emmenegger, Yann, Gobet, Cédric, Franken, Paul, Gachon, Frédéric and Naef, Félix (2018). Clock-dependent chromatin topology modulates circadian transcription and behavior. Genes & Development, 32 (5-6), 347-358. doi: 10.1101/gad.312397.118

Clock-dependent chromatin topology modulates circadian transcription and behavior

2017

Journal Article

Transcription factor activity rhythms and tissue-specific chromatin interactions explain circadian gene expression across organs

Yeung, Jake, Mermet, Jérôme, Jouffe, Céline, Marquis, Julien, Charpagne, Aline, Gachon, Frédéric and Naef, Felix (2017). Transcription factor activity rhythms and tissue-specific chromatin interactions explain circadian gene expression across organs. Genome Research, 28 (2), 182-191. doi: 10.1101/gr.222430.117

Transcription factor activity rhythms and tissue-specific chromatin interactions explain circadian gene expression across organs

2017

Journal Article

Diurnal liver mass is associated with ribosome biogenesis

Sinturel, Flore and Gachon, Frederic (2017). Diurnal liver mass is associated with ribosome biogenesis. Oncotarget, 8 (57), 96476-96477. doi: 10.18632/oncotarget.22255

Diurnal liver mass is associated with ribosome biogenesis