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2017

Journal Article

Transcriptional regulatory logic of the diurnal cycle in the mouse liver

Sobel, Jonathan Aryeh, Krier, Irina, Andersin, Teemu, Raghav, Sunil, Canella, Donatella, Gilardi, Federica, Kalantzi, Alexandra Styliani, Rey, Guillaume, Weger, Benjamin, Gachon, Frederic, Dal Peraro, Matteo, Hernandez, Nouria, Schibler, Ueli, Deplancke, Bart and Naef, Felix (2017). Transcriptional regulatory logic of the diurnal cycle in the mouse liver. Plos Biology, 15 (4) e2001069, e2001069. doi: 10.1371/journal.pbio.2001069

Transcriptional regulatory logic of the diurnal cycle in the mouse liver

2017

Journal Article

Regulation of mammalian physiology by interconnected circadian and feeding rhythms

Atger, Florian, Mauvoisin, Daniel, Weger, Benjamin, Gobet, Cedric and Gachon, Frederic (2017). Regulation of mammalian physiology by interconnected circadian and feeding rhythms. Frontiers in Endocrinology, 8 (MAR) 42. doi: 10.3389/fendo.2017.00042

Regulation of mammalian physiology by interconnected circadian and feeding rhythms

2017

Journal Article

Pancreatic alpha- and beta-cellular clocks have distinct molecular properties and impact on islet hormone secretion and gene expression

Petrenko, Volodymyr, Saini, Camille, Giovannoni, Laurianne, Gobet, Cedric, Sage, Daniel, Unser, Michael, Masson, Mounia Heddad, Gu, Guoqiang, Bosco, Domenico, Gachon, Frederic, Philippe, Jacques and Dibner, Charna (2017). Pancreatic alpha- and beta-cellular clocks have distinct molecular properties and impact on islet hormone secretion and gene expression. Genes and Development, 31 (4), 383-398. doi: 10.1101/gad.290379.116

Pancreatic alpha- and beta-cellular clocks have distinct molecular properties and impact on islet hormone secretion and gene expression

2017

Journal Article

Nuclear proteomics uncovers diurnal regulatory landscapes in mouse liver

Wang, Jingkui, Mauvoisin, Daniel, Martin, Eva, Atger, Florian, Galindo, Antonio Nunez, Dayon, Loic, Sizzano, Federico, Palini, Alessio, Kussmann, Martin, Waridel, Patrice, Quadroni, Manfredo, Dulic, Vjekoslav, Naef, Felix and Gachon, Frederic (2017). Nuclear proteomics uncovers diurnal regulatory landscapes in mouse liver. Cell Metabolism, 25 (1), 102-117. doi: 10.1016/j.cmet.2016.10.003

Nuclear proteomics uncovers diurnal regulatory landscapes in mouse liver

2016

Journal Article

Extensive regulation of diurnal transcription and metabolism by glucocorticoids

Weger, Benjamin D., Weger, Meltem, Goerling, Benjamin, Schink, Andrea, Gobet, Cedric, Keime, Celine, Poschet, Gernot, Jost, Bernard, Krone, Nils, Hell, Ruediger, Gachon, Frederic, Luy, Burkhard and Dickmeis, Thomas (2016). Extensive regulation of diurnal transcription and metabolism by glucocorticoids. PLoS Genetics, 12 (12) e1006512, e1006512. doi: 10.1371/journal.pgen.1006512

Extensive regulation of diurnal transcription and metabolism by glucocorticoids

2016

Journal Article

Perturbed rhythmic activation of signaling pathways in mice deficient for Sterol Carrier Protein 2-dependent diurnal lipid transport and metabolism

Jouffe, Celine, Gobet, Cedric, Martin, Eva, Metairon, Sylviane, Morin-Rivron, Delphine, Masoodi, Mojgan and Gachon, Frederic (2016). Perturbed rhythmic activation of signaling pathways in mice deficient for Sterol Carrier Protein 2-dependent diurnal lipid transport and metabolism. Scientific Reports, 6 (1) 24631. doi: 10.1038/srep24631

Perturbed rhythmic activation of signaling pathways in mice deficient for Sterol Carrier Protein 2-dependent diurnal lipid transport and metabolism

2016

Journal Article

USP2-45 is a circadian clock output effector regulating calcium absorption at the post-translational level

Pouly, Daniel, Chenaux, Sebastien, Martin, Virginie, Babis, Maja, Koch, Rafael, Nagoshi, Emi, Katanaev, Vladimir L., Gachon, Frederic and Staub, Olivier (2016). USP2-45 is a circadian clock output effector regulating calcium absorption at the post-translational level. Plos One, 11 (1) e0145155, e0145155. doi: 10.1371/journal.pone.0145155

USP2-45 is a circadian clock output effector regulating calcium absorption at the post-translational level

2015

Journal Article

Circadian and feeding rhythms differentially affect rhythmic mRNA transcription and translation in mouse liver

Atger, Florian, Gobet, Cedric, Marquis, Julien, Martin, Eva, Wang, Jingkui, Weger, Benjamin, Lefebvre, Gregory, Descombes, Patrick, Naef, Felix and Gachon, Frederic (2015). Circadian and feeding rhythms differentially affect rhythmic mRNA transcription and translation in mouse liver. Proceedings of the National Academy of Sciences of the United States of America, 112 (47), E6579-E6588. doi: 10.1073/pnas.1515308112

Circadian and feeding rhythms differentially affect rhythmic mRNA transcription and translation in mouse liver

2015

Journal Article

Circadian dysfunction and obesity: is leptin the missing link?

Dibner, Charna and Gachon, Frederic (2015). Circadian dysfunction and obesity: is leptin the missing link?. Cell Metabolism, 22 (3), 359-360. doi: 10.1016/j.cmet.2015.08.008

Circadian dysfunction and obesity: is leptin the missing link?

2015

Journal Article

Proteomics and circadian rhythms: it's all about signaling!

Mauvoisin, Daniel, Dayon, Loic, Gachon, Frederic and Kussmann, Martin (2015). Proteomics and circadian rhythms: it's all about signaling!. Proteomics, 15 (2-3), 310-317. doi: 10.1002/pmic.201400187

Proteomics and circadian rhythms: it's all about signaling!

2014

Journal Article

Local renal circadian clocks control fluid-electrolyte homeostasis and BP

Tokonami, Natsuko, Mordasini, David, Pradervand, Sylvain, Centeno, Gabriel, Jouffe, Celine, Maillard, Marc, Bonny, Olivier, Gachon, Frederic, Gomez, R. Ariel, Sequeira-Lopez, Maria Luisa S. and Firsov, Dmitri (2014). Local renal circadian clocks control fluid-electrolyte homeostasis and BP. Journal of the American Society of Nephrology, 25 (7), 1430-1439. doi: 10.1681/ASN.2013060641

Local renal circadian clocks control fluid-electrolyte homeostasis and BP

2014

Journal Article

Circadian clock-dependent and -independent rhythmic proteomes implement distinct diurnal functions in mouse liver

Mauvoisin, Daniel, Wang, Jingkui, Jouffe, Celine, Martin, Eva, Atger, Florian, Waridel, Patrice, Quadroni, Manfredo, Gachon, Frederic and Naef, Felix (2014). Circadian clock-dependent and -independent rhythmic proteomes implement distinct diurnal functions in mouse liver. Proceedings of the National Academy of Sciences of the United States of America, 111 (1), 167-172. doi: 10.1073/pnas.1314066111

Circadian clock-dependent and -independent rhythmic proteomes implement distinct diurnal functions in mouse liver

2014

Journal Article

Chronopharmacology: new insights and therapeutic implications

Dallmann, Robert, Brown, Steven A. and Gachon, Frederic (2014). Chronopharmacology: new insights and therapeutic implications. Annual Review of Pharmacology and Toxicology, 54 (1), 339-361. doi: 10.1146/annurev-pharmtox-011613-135923

Chronopharmacology: new insights and therapeutic implications

2013

Journal Article

The circadian clock coordinates ribosome biogenesis

Jouffe, Celine, Cretenet, Gaspard, Symul, Laura, Martin, Eva, Atger, Florian, Naef, Felix and Gachon, Frederic (2013). The circadian clock coordinates ribosome biogenesis. Plos Biology, 11 (1) e1001455, e1001455. doi: 10.1371/journal.pbio.1001455

The circadian clock coordinates ribosome biogenesis

2011

Journal Article

Proline- and acidic amino acid-rich basic leucine zipper proteins modulate peroxisome proliferator-activated receptor alpha (PPAR alpha) activity

Gachon, Frederic, Leuenberger, Nicolas, Claudel, Thierry, Gos, Pascal, Jouffe, Celine, Olela, Fabienne Fleury, du Jeu, Xavier de Mollerat, Wahli, Walter and Schibler, Ueli (2011). Proline- and acidic amino acid-rich basic leucine zipper proteins modulate peroxisome proliferator-activated receptor alpha (PPAR alpha) activity. Proceedings of the National Academy of Sciences of the United States of America, 108 (12), 4794-4799. doi: 10.1073/pnas.1002862108

Proline- and acidic amino acid-rich basic leucine zipper proteins modulate peroxisome proliferator-activated receptor alpha (PPAR alpha) activity

2011

Journal Article

The role of circadian timing system on drug metabolism and detoxification

Gachon, Frederic and Firsov, Dmitri (2011). The role of circadian timing system on drug metabolism and detoxification. Expert Opinion On Drug Metabolism and Toxicology, 7 (2), 147-158. doi: 10.1517/17425255.2011.544251

The role of circadian timing system on drug metabolism and detoxification

2010

Journal Article

Cardiac hypertrophy, low blood pressure, and low aldosterone levels in mice devoid of the three circadian PAR bZip transcription factors DBP, HLF, and TEF

Wang, Qing, Maillard, Marc, Schibler, Ueli, Burnier, Michel and Gachon, Frederic (2010). Cardiac hypertrophy, low blood pressure, and low aldosterone levels in mice devoid of the three circadian PAR bZip transcription factors DBP, HLF, and TEF. American Journal of Physiology-Regulatory Integrative and Comparative Physiology, 299 (4), R1013-R1019. doi: 10.1152/ajpregu.00241.2010

Cardiac hypertrophy, low blood pressure, and low aldosterone levels in mice devoid of the three circadian PAR bZip transcription factors DBP, HLF, and TEF

2010

Journal Article

Circadian clock-coordinated hepatic lipid metabolism: only transcriptional regulation?

Gachon, Frederic and Bonnefont, Xavier (2010). Circadian clock-coordinated hepatic lipid metabolism: only transcriptional regulation?. Aging, 2 (2), 101-106. doi: 10.18632/aging.100123

Circadian clock-coordinated hepatic lipid metabolism: only transcriptional regulation?

2010

Journal Article

Circadian clock-coordinated 12 hr period rhythmic activation of the IRE1 alpha pathway controls lipid metabolism in mouse liver

Cretenet, Gaspard, Le Clech, Mikael and Gachon, Frederic (2010). Circadian clock-coordinated 12 hr period rhythmic activation of the IRE1 alpha pathway controls lipid metabolism in mouse liver. Cell Metabolism, 11 (1), 47-57. doi: 10.1016/j.cmet.2009.11.002

Circadian clock-coordinated 12 hr period rhythmic activation of the IRE1 alpha pathway controls lipid metabolism in mouse liver

2007

Journal Article

Crosstalk between xenobiotics metabolism and circadian clock

Claudel, Thierry, Cretenet, Gaspard, Saumet, Anne and Gachon, Frederic (2007). Crosstalk between xenobiotics metabolism and circadian clock. Febs Letters, 581 (19), 3626-3633. doi: 10.1016/j.febslet.2007.04.009

Crosstalk between xenobiotics metabolism and circadian clock