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2000 Conference Publication The biotransformation of tamoxifen by human vytochrome P450 enzymes leads to the production of potentially genotoxic metabolitesNotley, L., Crewe, K. H., Lennard, M. S. and Gillam, E. M. J. (2000). The biotransformation of tamoxifen by human vytochrome P450 enzymes leads to the production of potentially genotoxic metabolites. ASCEPT Annual Scientific Meeting 2000, Newcastle, Australia, 3 - 6 December, 2000. Sydney, Australia: ASCEPT. |
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2000 Conference Publication Examining tissue-specific bioactivation in vitro: Cytochrome P450 1B1 and other extrahepatic forms in the metabolism of carcinogensGillam, E. M. J., Notley, L., Guengerich, F. P., Shimada, T. and Lennard, M. S. (2000). Examining tissue-specific bioactivation in vitro: Cytochrome P450 1B1 and other extrahepatic forms in the metabolism of carcinogens. Pacifichem 2000 Proceedings, Honolulu, USA, 13 - 20 December, 2000. American Chemical Society. |
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1998 Conference Publication Expression of human cytochrome P4501B1 in bacteriaGuengerich, FP, Shimada, T, Gillam, EMJ, Sutter, TR and Wunsch, RM (1998). Expression of human cytochrome P4501B1 in bacteria. BETHESDA: FEDERATION AMER SOC EXP BIOL. |
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1998 Conference Publication Analysis of cytochrome P450 2D6 : substrate interactions by site-directed mutagenesisHanna, IH, Gillam, EMJ and Guengerich, FP (1998). Analysis of cytochrome P450 2D6 : substrate interactions by site-directed mutagenesis. BETHESDA: FEDERATION AMER SOC EXP BIOL. |
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1997 Conference Publication Comparison of reconstitution conditions for recombinant human P450 2C9 with systems containing P450S 1A1, 1A2, 2D6, 2E1, and 3A4. Effects of P450-P450 and P450-b(5) interactionsYamazaki, H, Gillam, EMJ, Dong, MS, Johnson, WW, Guengerich, FP and Shimada, T (1997). Comparison of reconstitution conditions for recombinant human P450 2C9 with systems containing P450S 1A1, 1A2, 2D6, 2E1, and 3A4. Effects of P450-P450 and P450-b(5) interactions. BETHESDA: FEDERATION AMER SOC EXP BIOL. |
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1997 Conference Publication Expression of P450 3A7 in Escherichia coli: Effects of 5' modification and catalytic characterization of the recombinant enzymeGillam, EMJ, Wunsch, RM, Ueng, YF, Shimada, T, Parikh, A, Kamataki, T and Guengerich, FP (1997). Expression of P450 3A7 in Escherichia coli: Effects of 5' modification and catalytic characterization of the recombinant enzyme. BETHESDA: FEDERATION AMER SOC EXP BIOL. |
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1995 Conference Publication Retention of N-Formylmethionine in Recombinant Bacterial Cytochrome-P450 Enzymes Containing the N-Terminal Sequence MalllavflDong, MS, Guo, Z, Philips, DR, Bell, LC, Howard, E, Blair, IA, Gillam, Emj, Baba, T, Waterman, MR and Guengerich, FP (1995). Retention of N-Formylmethionine in Recombinant Bacterial Cytochrome-P450 Enzymes Containing the N-Terminal Sequence Malllavfl. BETHESDA: FEDERATION AMER SOC EXP BIOL. |
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1994 Conference Publication Expression and Purification of Human Cytochrome-P450 Enzymes From Escherichia-ColiGuo, Z, Sandhu, P, Gillam, Emj, Martin, MV and Guengerich, FP (1994). Expression and Purification of Human Cytochrome-P450 Enzymes From Escherichia-Coli. BETHESDA: FEDERATION AMER SOC EXP BIOL. |
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1994 Conference Publication Mechanisms of Enhancement and Inhibition of Cytochrome-P450 Catalytic ActivitiesGuengerich, FP, Kim, BR, Gillam, Emj and Shimada, T (1994). Mechanisms of Enhancement and Inhibition of Cytochrome-P450 Catalytic Activities. 8th International Conference on Cytochrome P450: Biochemistry, Biophysics and Molecular Biology, Lisbon Portugal, Oct 24-28, 1993. MONTROUGE: JOHN LIBBEY EUROTEXT LTD. |
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1993 Conference Publication Expression of Human Cytochrome-P450 Enzymes in Escherichia-Coli, Purification, and Reconstitution of Catalytic ActivitySandhu, P, Gillam, Emj, Baba, T, Kim, BR and Guengerich, FP (1993). Expression of Human Cytochrome-P450 Enzymes in Escherichia-Coli, Purification, and Reconstitution of Catalytic Activity. BETHESDA: FEDERATION AMER SOC EXP BIOL. |
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1993 Conference Publication 3-Alpha-Hydroxylation and 8,9-Epoxidation of Aflatoxin-B(1) by Cytochrome-P450-3A4 - Evidence for Allosteric Behavior in Microsomal-Membranes and a Recombinant EnzymeKim, BR, Baba, T, Gillam, Emj and Guengerich, FP (1993). 3-Alpha-Hydroxylation and 8,9-Epoxidation of Aflatoxin-B(1) by Cytochrome-P450-3A4 - Evidence for Allosteric Behavior in Microsomal-Membranes and a Recombinant Enzyme. BETHESDA: FEDERATION AMER SOC EXP BIOL. |
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1992 Conference Publication Expression of Human Cytochrome-P-450-3A4 and Cytochrome-P450-2E1 in the Bacterium Escherichia-ColiGillam, Emj, Omori, S, Sandhu, P and Guengerich, FP (1992). Expression of Human Cytochrome-P-450-3A4 and Cytochrome-P450-2E1 in the Bacterium Escherichia-Coli. BETHESDA: FEDERATION AMER SOC EXP BIOL. |
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1991 Conference Publication Spectral Studies Investigating the Binding of Cyclosporine-A to Hepatic Cytochromes-P450Gillam, Emj and Harvey, DJ (1991). Spectral Studies Investigating the Binding of Cyclosporine-A to Hepatic Cytochromes-P450. 4Th International Symp On the Biological Oxidation of Nitrogen in Organic Molecules, Munich Fed Rep Ger, Sep 17-21, 1989. STUTTGART: GUSTAV FISCHER VERLAG. |
