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2022

Book Chapter

Using the evolutionary history of proteins to engineer insertion-deletion mutants from robust, ancestral templates using Graphical Representation of Ancestral Sequence Predictions (GRASP)

Ross, Connie M., Foley, Gabriel, Boden, Mikael and Gillam, Elizabeth M. J. (2022). Using the evolutionary history of proteins to engineer insertion-deletion mutants from robust, ancestral templates using Graphical Representation of Ancestral Sequence Predictions (GRASP). Enzyme engineering. (pp. 85-110) edited by Francesca Magnani, Chiara Marabelli and Francesca Paradisi. New York, NY, United States: Humana Press. doi: 10.1007/978-1-0716-1826-4_6

Using the evolutionary history of proteins to engineer insertion-deletion mutants from robust, ancestral templates using Graphical Representation of Ancestral Sequence Predictions (GRASP)

2022

Book Chapter

Use of engineered cytochromes P450 for accelerating drug discovery and development

Thomson, Raine E.S., D'Cunha, Stephlina A., Hayes, Martin A. and Gillam, Elizabeth M.J. (2022). Use of engineered cytochromes P450 for accelerating drug discovery and development. Pharmacology and toxicology of cytochrome P450 – 60th anniversary. (pp. 195-252) edited by Hiroshi Yamazaki. Cambridge, MA, United States: Academic Press. doi: 10.1016/bs.apha.2022.06.001

Use of engineered cytochromes P450 for accelerating drug discovery and development

2020

Book Chapter

Directed evolution of enzymes

Jackson, Colin J., Gillam, Elizabeth M.J. and Ollis, David L. (2020). Directed evolution of enzymes. Comprehensive Natural Products III: Chemistry and biology. (pp. 654-673) London, United Kingdom: Elsevier. doi: 10.1016/B978-008045382-8.00675-4

Directed evolution of enzymes

2014

Book Chapter

Computational tools for directed evolution: a comparison of prospective and retrospective strategies

Zaugg, Julian, Gumulya, Yosephine, Gillam, Elizabeth M. J. and Bodén, Mikael (2014). Computational tools for directed evolution: a comparison of prospective and retrospective strategies. Directed evolution library creation: methods and protocols. (pp. 315-333) edited by Elizabeth M. J. Gillam, Janine N. Copp and David F. Ackerley. New York, NY, United States: Humana Press. doi: 10.1007/978-1-4939-1053-3_21

Computational tools for directed evolution: a comparison of prospective and retrospective strategies

2014

Book Chapter

Preface

Gillam, Elizabeth M. J., Copp, Janine N. and Ackerley, David F. (2014). Preface. Directed evolution library creation: methods and protocols. (pp. v-vi) edited by Elizabeth M.J. Gillam, Janine N. Copp and David Ackerley. New York, NY United States: Humana Press.

Preface

2013

Book Chapter

Measurement of P450 difference spectra using intact cells

Johnston, Wayne A. and Gillam, Elizabeth M. J. (2013). Measurement of P450 difference spectra using intact cells. Cytochrome P450 protocols. (pp. 189-204) edited by Ian R. Phillips, Elizabeth A. Shepherd and Paul R. Ortiz de Montellano. New York, NY, United States: Humana Press. doi: 10.1007/978-1-62703-321-3_17

Measurement of P450 difference spectra using intact cells

2013

Book Chapter

DNA shuffling of cytochrome P450 enzymes

Behrendorff, James B. Y. H., Johnston, Wayne A. and Gillam, Elizabeth M. J. (2013). DNA shuffling of cytochrome P450 enzymes. Cytochrome P450 protocols. (pp. 177-188) edited by Ian R. Phillips, Elizabeth A. Shepherd and Paul R. Ortiz de Montellano. New York, NY, United States: Humana Press. doi: 10.1007/978-1-62703-321-3_16

DNA shuffling of cytochrome P450 enzymes

2010

Book Chapter

Directed evolution of enzymes

Jackson, Colin J., Gillam, Elizabeth M. J. and Ollis, David L. (2010). Directed evolution of enzymes. Comprehensive natural products II chemistry and biology. (pp. 723-749) edited by Lewis Mander and Hung-Wen Liu. Oxford, England, Unied Kingdom: Elsevier.

Directed evolution of enzymes

2007

Book Chapter

Chemical Defence and Exploitation: Biotransformation of Xenobiotics by Cytochrome P450 Enzymes

Gillam, E. M. J. and Hunter, D. J. B. (2007). Chemical Defence and Exploitation: Biotransformation of Xenobiotics by Cytochrome P450 Enzymes. Metal Ions in Life Sciences. (pp. 477-560) edited by Astrid Sigel, Helmut Sigel and Roland K. O. Sigel. West Sussex: John Wiley and sons. doi: 10.1002/9780470028155.ch15

Chemical Defence and Exploitation: Biotransformation of Xenobiotics by Cytochrome P450 Enzymes